Researchers visualize radiation-induced breakage of specific chemical bonds in protein, revealing a highly specific phenomenon. The findings have direct implications for improving data collection using X-ray crystallography and developing pharmacological means to protect against radiation damage.
Researchers have made significant breakthroughs in functional MRI technology, enabling accurate mapping of cortical columns, the brain's microprocessors. This advancement will greatly improve our understanding of human perception and higher cognitive functions.
Researchers discovered diverse types of inhibitory neurons that filter messages to neighbors, enabling precise control over brain activity. This design principle allows for complex and fine-grained inhibition, potentially leading to novel treatments for neurological disorders.
Researchers at Weizmann Institute have discovered the 3-D interaction between galanthamine and brain enzyme acetylcholinesterase (AChE), which breaks down neurotransmitter acetylcholine in Alzheimer's disease. This finding may lead to a new family of drugs with reduced side effects.
Researchers have deciphered part of the cellular events underlying apoptosis, providing insights into cancer pathologies and potential cures. The cooperation between c-Abl and p73 leads to cell death, highlighting their roles in safeguarding the cell against DNA damage.
Weizmann Institute researchers find a family of amino acid analogues that effectively regulate glucose levels in diabetic laboratory animals. The new compounds have greater antidiabetic potency than vanadium alone, offering a promising treatment option for type II diabetes.
Researchers at the Weizmann Institute developed a molecule that allows blood stem cells to multiply without differentiation in the test tube, improving bone marrow transplantation and gene therapy research. This breakthrough could enable scientists to insert genes into human stem cells for treating genetic disorders.
Researchers at the Weizmann Institute have developed a new treatment for a myasthenia gravis-like disease in rats by administering genetically engineered receptor fragments through the nose. The approach may serve as a basis for treating this autoimmune disease in humans, where symptoms can be life-threatening.
Scientists at the Weizmann Institute discovered that bacterial DNA forms a crystalline organization when exposed to stress, providing effective protection against oxidative agents and starvation. This finding may lead to the development of more efficient methods to fight bacterial diseases.
Researchers have discovered that specialized proteins in the nose called olfactory receptors can bind with multiple odor molecules, creating a unique 'fingerprint' that the brain understands as a particular smell. This discovery could lead to new fragrances and flavors, as well as artificial smell sensors.
In an experiment, Weizmann Institute scientists succeeded in measuring the smallest electronic charge, equal to one-fifth the charge of a single electron. This measurement was made using a different electronic system, proving that it refers solely to the electronic charge itself.
A team of scientists has discovered that a type of experimental semiconductor can repair itself after damage, thanks to its unique ability to move atomic bonds back into place. This 'self-healing' property could lead to the creation of more stable and effective solar cells.
Researchers found elevated TGase activity in postmortem brain tissue of HD patients, linking it to htt aggregation and nuclear inclusion formation. This novel finding appears to counter previous findings on amyloid protein deposits and the 'protein zipper' hypothesis.
Researchers have found a link between beta-catenin and cyclin D1 in colon cancer cells, leading to uncontrolled cell growth and tumor formation. This discovery may lead to new therapies for colon cancer and potentially other types of cancer.
Weizmann Institute scientists develop a heat-shock protein-based vaccine that triggers high-performance antibodies against bacterial infections, providing nearly complete protection against lethal doses. The new approach may lead to improved vaccines for various diseases and potentially cancer therapy.
Researchers at Weizmann Institute identify protein IL-18BP, which blocks production of interferon-gamma in T cells, a major substance released by immune cells under the influence of interleukin 18. This discovery may lead to new treatments for autoimmune diseases and organ transplants.
Researchers discovered that human stem cells use a specific receptor, CXCR4, to migrate to bone marrow. Treating stem cells with growth factors increased their ability to express this receptor and migrate successfully, improving transplant success rates from 25% to over 90%.
Prof. Michal Schwartz's research reveals a unique relationship between the central nervous system and immune system, showing that immune cells can aid in healing damaged nerves. This discovery may lead to new treatments for nerve damage and autoimmune diseases like multiple sclerosis.
A study by Weizmann Institute of Science and Perugia University in Italy has found that mismatched bone marrow transplants can be as effective as fully matched transplants, overcoming key obstacles such as graft failure and immunological reaction. The method, which uses extremely large doses of donor marrow, has raised hopes for increa...
Weizmann Institute scientists have created a new class of magnetic materials made of clusters of inorganic molecules, opening up research possibilities for the microelectronics industry. The new magnets display an unusual combination of properties that make them suitable for miniaturization and potential industrial applications.
Researchers at the Weizmann Institute created a 2D system to study fire propagation, revealing that flame dynamics follow simple laws governing penetration of liquids into porous materials. This breakthrough provides a low-cost alternative to studying fire in space and could aid in detecting slow-moving flames in aircraft.
A research team led by Prof. Yitzhak Maron has developed a method to definitively determine how electricity flows through hot and dense plasmas. By measuring the electric current and its distribution in the plasma, scientists can gain crucial information on how to condense plasma more effectively for controlled fusion.
Researchers at the Weizmann Institute of Science have revealed the molecular repair mechanism known as S.O.S. repair, which fixes DNA damage and introduces random genetic material to create a beneficial mutation. This discovery provides new insights into diseases like cancer and bacterial resistance to antibiotics.
A 2,000-year-old climate warming event was discovered in East Africa by analyzing sediment cores from a high-altitude lake. This study suggests that the climate can warm up suddenly without human activity, providing new insights into past climate fluctuations and potentially informing predictions about future climate change.
Weizmann Institute scientists develop a novel approach to heal damaged spinal cords in rats, regaining partial motor activity and movement. The treatment promotes the animal's own self-repair mechanism, paving the way for further research on human applications.
Scientists have discovered that antibodies can recognize the orientation of amino acids, allowing them to bind only with specific handedness. This ability may be key to developing new, effective pharmaceuticals by identifying and sorting out left- and right-handed molecules.
A new method for clustering data on computers has been developed by Prof. Eytan Domany, enabling the analysis of vast amounts of information without prior knowledge of its structure or categories. The algorithm mimics human intuition and can automatically identify clusters in various types of data.
Researchers found that at high temperatures, a phenomenon called the surface barrier slows down columns of dynamic magnetic fields, allowing current to flow along the edge. This discovery throws new light on superconductor properties and may lead to advanced materials with improved properties.
Researchers at the Weizmann Institute of Science demonstrate that observing electrons alters their behavior, changing from wave-like to particle-like behavior. The study shows that increasing detection can weaken interference patterns, while reducing detection strengthens them.
Professors Michael Sela and Ruth Arnon have made significant contributions to the field of immunology with their development of synthetic vaccines and peptides. Their work has led to safer and more effective treatments for infectious diseases and autoimmune disorders.
Researchers have developed new 'green' materials derived from chlorophyll, which can be used to overcome limitations of photodynamic therapy (PDT) for treating bulky solid tumors. These materials can kill cancer cells in tissue culture and mice while minimizing side effects.
A new study reveals that insulin resistance, a precursor to diabetes, is caused by a cellular 'short circuit' triggered by excessive protein phosphorylation and TNF secretion, potentially explaining the link between obesity and insulin resistance.
A new study reveals that adjusting the structural orientation of a soluble catalyst's molecules can dramatically improve its catalytic efficiency and selectivity. The researchers found that neatly arranged molecules are more efficient and easier to control chemical reactions.
Researchers outline three unique features that may distinguish strange stars from neutron stars, including higher X-ray energy and pulse emissions. The discovery of a strange star could prove the existence of quark matter, a form of matter made up of quarks.
A new study using optical imaging reveals that brain cells engaged in different tasks form mosaics with remarkable order and elegance. The research may assist in the development of artificial vision systems.
A new method using tiny Micro-Tom tomatoes enables scientists to identify and use commercially valuable genes in plants, cutting the time necessary for mutations by half. This allows for large-scale analysis of plant genomes and customization of fruits and vegetables.
Researchers found that imagining visual stimuli activates short-term memory, lowering the threshold of brightness for visual perception. This phenomenon suggests separate neural mechanisms control short- and long-term visual memory, with imagination enhancing visual abilities.
A new delivery system may allow for more precise control over where new genes are inserted into an organism's chromosomes, improving gene therapy. The approach uses parvoviruses to target specific locations on the chromosomes, reducing the risk of genes causing harm or functioning poorly.
A study by Weizmann researchers suggests that a cell-suicide gene called DAP-kinase can prevent metastasis in cancer. The gene's proper functioning is essential for cells to die during different stages of metastasis, and its loss or malfunction can lead to unwanted cell proliferation and tumor development.
Two repair proteins, Fpg and UvrA, have been found to 'block the road' to replication by physically attaching themselves to damaged DNA, preventing mutations. This discovery offers new insights into natural DNA repair mechanisms and potential avenues for cancer prevention.
A new study reveals that adult-onset diabetics may be suffering from an 'imbalancing act' caused by a key enzyme called PFK, which regulates glucose metabolism. The researchers found that mice with abnormally high levels of the PFK-L sub-unit developed symptoms of Type II diabetes.
Researchers at Weizmann Institute of Science find that muscle and tendon cells communicate through a molecular dialogue to complete their differentiation process. They isolated a gene that produces a growth factor inducing tendon cell differentiation, potentially helping understand human embryonic muscle development.
Researchers studied how garlic works at the molecular level, finding allicin disables dysentery-causing amoebas by blocking enzymes. This discovery supports garlic as a broad-spectrum antimicrobial drug with potential implications for fighting bacterial resistance and preventing heart disease.
Research at the Weizmann Institute found that the brain uses a frequency modulation (FM) receiver-like mechanism to decode sensory information gathered through touch. This discovery provides a possible new explanation for how the brain processes sensory input, and could lead to advances in understanding the neural code.
Researchers at the Weizmann Institute of Science have confirmed the existence of fractional electric charges, one-third that of an electron, in a groundbreaking experiment. The team measured the charge using sophisticated equipment to eliminate noise and detected ripples proportional to the unit of electric charge.
A new approach to math education, developed by Dr. Alex Friedlander, focuses on investigative experiences that motivate children to discover mathematical principles. This method encourages creative problem-solving and allows advanced students to learn at their own pace.
Researchers developed a molecular radar system to track signaling enzymes inside cells, allowing them to map the exact progress of intercellular messengers during embryonic development. This achievement has valuable implications for understanding how signals are transferred inside cells and how they go awry in diseases like cancer.
A Weizmann Institute study suggests that master-key antibodies interact with proline on proteins and protein fragments to escort them out of the body. This research provides scientific basis for theory that these antibodies may remove broad range of unneeded proteins without affecting beneficial ones.
Scientists at the Weizmann Institute successfully created uniformly oriented crystals of varying sizes by fine-tuning the small remaining mismatch between two materials. The method, using a technique called electrodeposition, holds promise for developing tiny semiconductors with new optoelectronic properties.
Researchers successfully controlled El Nino's behavior in a complex prediction model by altering values for deep ocean waves. This achievement may help improve El Nino event predictions, leading to measures that reduce global damage.