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Duke University


Duke chemists synthesize promising anti-cancer product

Researchers at Duke University have synthesized largazole, a marine algae extract with potential as an anti-cancer agent. The team's efficient synthetic route enables the production of gram-sized quantities, paving the way for further study and potential treatment of various cancers.

SourceDuke University·JournalJournal of the American Chemical Society·DateAug 20, 2008

Little teeth suggest big jump in primate timeline

The discovery of tiny fossilized teeth from India pushes the primate timeline back by almost 10 million years, revealing a new genus and species of anthropoid primates. The findings suggest these early primates lived on a fruit and insect diet and were no larger than modern dwarf lemurs.

SourceDuke University·JournalProceedings of the National Academy of Sciences·DateAug 4, 2008

Scattered light reveals size and shape of the nucleus

Researchers at Duke University have developed a new method to measure the size and shape of the nucleus in living cells, using angle-resolved low coherence interferometry (a/LCI). This technique allows for rapid and accurate measurements, enabling scientists to better understand how changes in nucleus shape influence gene expression.

SourceDuke University·JournalBiophysical Journal·DateMay 29, 2008

Small primate ancestors had a leg up

Researchers found that smaller primates have an evolutionary edge due to their ability to climb with minimal energy expenditure. This discovery challenges the longstanding assumption that climbing is energetically expensive for all primates.

SourceDuke University·JournalScience·DateMay 15, 2008

Genetic 'tag team' keeps cells on cycle

Researchers at Duke University have discovered a genetic 'tag team' that regulates the cell cycle, finding that nearly 70% of periodic genes continue to turn on and off without cyclins. The study suggests a new understanding of gene regulation in mammalian cells.

SourceDuke University·JournalNature·DateMay 7, 2008

First steps toward autonomous robot surgeries

Researchers at Duke University have made significant advancements in autonomous robot surgeries, demonstrating the feasibility of robots performing complex procedures under real-time 3-D ultrasound guidance. The technology has the potential to improve patient safety by reducing radiation exposure and enhancing surgeon precision.

New 3-D ultrasound could improve stroke diagnosis, care

Researchers at Duke University have developed a new 3-D ultrasound technology that can see in real-time the arteries within the brain, improving stroke diagnosis and care. The technology uses advanced imaging techniques to compensate for the thickness and unevenness of the skull, allowing for faster and more accurate diagnoses.

SourceDuke University·JournalUltrasound in Medicine & Biology·DateApr 24, 2008

Nanotubes grown straight in large numbers

Researchers have successfully grown aligned and straight single-walled carbon nanotubes in large numbers using a quartz surface as a template. The achievement marks a significant step forward for the development of nano-scale electronics, which could enable the creation of ultra-tiny chips with improved performance.

SourceDuke University·JournalJournal of the American Chemical Society·DateApr 23, 2008

Slowly-developing primates definitely not dim-witted

A new study by Duke University researchers found that big-brained primates, such as humans and chimpanzees, live longer and have more complex social skills due to their larger brain size. This extended life span allows them to reproduce for a longer period, increasing their chances of survival and passing on their genes.

SourceDuke University·JournalJournal of Human Evolution·DateApr 16, 2008

Novel living system recreates predator-prey interaction

Researchers created a living system using genetically altered bacteria to study the dynamics of interacting populations. The system, which consists of two distinct populations of bacteria that control each other's survival rates, provides a unique model for exploring population changes in a predictable manner.

SourceDuke University·JournalMolecular Systems Biology·DateApr 14, 2008

Findings could improve fuel cell efficiency

Researchers at Duke University have developed a ceramic membrane that allows fuel cells to operate at low humidity and higher temperatures, potentially improving efficiency. This new membrane could address current limitations in fuel cell technology and attract investment for its commercialization.

SourceDuke University·JournalJournal of Membrane Science·DateMar 19, 2008

Costly placebo works better than cheap one

A provocative study by Dan Ariely found that a 10-cent pill is less effective at killing pain than a $2.50 pill, even when they are identical placebos. The study suggests that patients' subjective ratings of pain are influenced by the perceived quality and cost of medications.

Why juniper trees can live on less water

Junipers' adaptation to avoid 'cavitation' allows them to withstand dry conditions, while their low specific leaf area enables them to conserve water. This study reveals the key structural features behind juniper trees' exceptional drought tolerance.

SourceDuke University·JournalAmerican Journal of Botany·DateFeb 27, 2008

Defining cancer's genetic 'support network'

Researchers at Duke University have developed a new method to model the genetic pathways underlying cancer, identifying connections between gene sets. The study reveals that specific gene sets work together to support cancer development and progression.

SourceDuke University·JournalPLOS Computational Biology·DateFeb 14, 2008

Heavy marijuana use linked to gum disease

A recent study has found that heavy marijuana use is associated with an increased risk of developing periodontal disease. The study, which tracked over 900 individuals, found that frequent cannabis use since age 18 was linked to more than one-third of new cases of gum disease between ages 26 and 32.

SourceDuke University·JournalJournal of the American Medical Association·DateFeb 5, 2008

Lower transmission increases dengue deaths

Researchers found that lower transmission rates increase dengue deaths by reducing the development of immunity to new strains during a critical cross-immunity period. This allows the virus to gain entry into cells and cause more severe infections.

SourceDuke University·JournalProceedings of the National Academy of Sciences·DateFeb 4, 2008

Baboon dads have surprising influence on daughters' fitness

Scientists have found that polygamous baboon fathers who spend time with their children during juvenile years can influence their daughters' fitness. The study, led by Duke University professor Susan Alberts, suggests that fatherly presence can give offspring a jump-start on reproduction, especially among females.

SourceDuke University·JournalProceedings of the National Academy of Sciences·DateFeb 4, 2008

Earth's soils bear unmistakable footprints of humans

A new global overview by Duke University soil scientist Daniel Richter emphasizes the need to address soil health due to increased cultivation, grazing, and logging. The study highlights the importance of long-term observation and analysis to understand how to sustain soils and minimize adverse effects on the environment.

SourceDuke University·JournalSoil Science·DateJan 25, 2008

'Invisibility cloaks' could break sound barriers

Researchers at Duke University have successfully created a three-dimensional sound cloak in theory, allowing sound waves to travel around it undistorted. This breakthrough could lead to improved acoustics in concert halls and hidden submarines from sonar detection.

SourceDuke University·JournalPhysical Review Letters·DateJan 9, 2008

High-energy ultrasound sharpens view of liver tumors

Researchers at Duke University developed a high-energy form of ultrasound imaging that produces clearer images of liver tumors. The Acoustic Radiation Force Impulse (ARFI) method uses sound waves to push on tissues, capturing their elasticity and stiffness, which can help distinguish between hard and soft tumors.

SourceDuke University·JournalPhysics in Medicine and Biology·DateJan 7, 2008

Reversible data transfers from light to sound

A team of researchers at Duke University has successfully transferred encoded information from a laser beam to sound waves and back again, opening the door for ultra-fast optical communications networks. The new method uses stimulated Brillouin scattering to create acoustic vibrations that can retain data for brief intervals.

SourceDuke University·JournalScience·DateDec 13, 2007

When to have a child? A new approach to the decision

Researchers developed a logical decision model to help women weigh the benefits of motherhood against its effects on career and social interests. The model suggests that having a child at a younger age may be better for women in their early careers, as taking a maternity leave has less impact on future career prospects.

SourceDuke University·JournalDecision Analysis·DateNov 7, 2007

Gene governs IQ boost from breastfeeding

A study of over 3,000 breastfed infants found that having the FADS2 gene variant increased intelligence by an average of nearly 7 IQ points. The researchers suggest that breastfeeding may account for these differences in intelligence due to the presence of certain fatty acids.

SourceDuke University·JournalProceedings of the National Academy of Sciences·DateNov 5, 2007

Screeners' hands quicker than eyes

Researchers found that screeners are more accurate in visual searches when allowed to correct their choices, but errors rise for rare targets. The study suggests improving airport security and cancer screening by addressing execution errors and perception issues separately.

SourceDuke University·JournalPsychological Science·DateOct 24, 2007

New paper examines dams' effects on California salmon

Researchers at Duke University warn that dams in California's Central Valley are harming spring-run Chinook salmon populations by blocking access to habitat and fragmenting these populations. The study suggests removing dams could help alleviate water shortages and aid fish species.

SourceDuke University·JournalJournal of Applied Ecology·DateSep 24, 2007

Separating the brain's 'bad' from 'good' iron

Researchers have created 'pro-chelators' that can selectively bind to potentially destructive forms of iron in the brain, reducing oxidative stress and cell damage associated with these diseases. The iron-binding agents are designed to target only harmful iron species, allowing benign forms to carry out vital functions.