A recent survey of 202 neonatologists and pediatricians found that the US healthcare system does not place enough emphasis on or dedicate sufficient resources to preventive healthcare for preterm infants. The survey also revealed key differences in care practices among doctors with varying levels of experience.
Dr. Elizabeth Blackburn, a UCSF biologist, has been awarded the L'Oreal-UNESCO prize for her pioneering work on telomere and telomerase research, which has led to a better understanding of cell aging and cancer. Her research aims to improve human well-being by developing interventions to prevent common diseases.
A recent survey found that nearly half of respondents would choose an endodontist for their root canal procedure. The American Association of Endodontists reports that endodontists perform an average of 25 root canals per week, significantly more than general dentists who perform about two a week.
A study by Kaiser Permanente and Harvard Medical School found that new mothers who slept five hours or less per day had a threefold higher risk for substantial weight retention (11 pounds or more) at their baby’s first birthday. Getting enough sleep, even just two hours more, may be as important as a healthy diet and exercise for new m...
LymphoStat-B achieved a sustained improvement in disease activity across multiple clinical measures and decreased the frequency of disease flares over time. The study also showed that LymphoStat-B was well-tolerated through 2.5 years on treatment, with comparable incidence rates of adverse events to placebo.
The Phase 2b study demonstrated that Albuferon achieved at least comparable efficacy and safety to peginterferon alfa-2a with a dosing regimen requiring half as many injections. Additionally, Albuferon showed less impairment of health-related quality of life on treatment.
The Phase 2b trial shows that Albuferon significantly reduces missed work days and improves health-related quality of life compared to peginterferon alfa-2a. Patients in the Albuferon treatment groups reported fewer days of missed work and less impairment of physical and mental health.
Synagis, a monoclonal antibody, is the standard of care for preventing severe RSV infections in high-risk infants. The new analysis found that preventing RSV early in life makes economic sense by reducing potential costs of future complications and improving quality of life.
MedImmune will present three abstracts at the AAP National Conference & Exhibition, including cost-effectiveness data for palivizumab prophylaxis among preterm infants. The company's surveillance program aims to track RSV activity nationwide and inform improved prevention guidelines.
A recent study presented at TCT symposium showed that the vast majority of patients who underwent MitraClip procedure did not need surgery three years later and experienced improved left ventricle function. The device also reduced mitral regurgitation severity and promoted reverse remodeling, leading to better patient outcomes.
A new research study found that chewing gum before an afternoon snack can significantly reduce calorie intake from snacks by 25 calories. Nutritionists say even small changes in calories can have a long-term impact on weight management.
MedImmune presents Phase 2 safety data for its anti-RSV antibody, motavizumab, in young children with a history of prematurity. The company also releases national RSV surveillance results showing regional variability of the virus in the southern United States.
The Phase II EPOC study found that ZD4054, an endothelin A receptor antagonist, showed no difference in progression-free survival but reported encouraging overall survival data. The compound may have potential to increase median overall survival time for men with asymptomatic or mildly symptomatic metastatic HRPC.
A survey of 543 breast cancer survivors found that women's knowledge about actions to reduce recurrence is low, despite being optimistic about their future. The majority reported feeling stronger and more hopeful after diagnosis.
A clinical trial is underway to assess the safety and efficacy of intravenous carbamazepine in adult patients with epilepsy. The new treatment aims to provide an alternative to oral therapy during hospitalization or when oral administration is not feasible.
New data from the Women's Health Initiative study show that women aged 50-59 taking oral estrogen therapy have significantly less coronary artery calcification compared to those taking placebo. This finding supports the initiation of estrogen therapy in these younger menopausal women to reduce bone loss and alleviate symptoms.
A $1.7 million grant will help improve and standardize hormone measurements, specifically testosterone, among laboratories nationwide. The project aims to better diagnose and manage hormone-related diseases like hypogonadism in men.
Almac Diagnostics plans to develop and clear its In Vitro Diagnostic for colorectal cancer using the 510(k) approach, accelerating regulatory submission. The company's prognostic gene signature was developed from FFPE samples and aims to help clinicians determine cancer recurrence risk in stage II CRC patients.
The Novo-TTF device has been shown to disrupt tumor growth by interfering with cell division of cancerous cells, causing them to stop proliferating and die off. In a pilot trial, 10 patients with recurring GBM experienced improved survival rates, with median overall survival doubling compared to historical data.
The 2007 L’Oréal USA Fellows are recognized for their innovative research in earth science, neuroscience, oceanography, physical chemistry, and biomedical engineering. Their work tackles key scientific issues and has the potential to shape the future of science and address global challenges.
Researchers found that adult men and postmenopausal women require significantly higher amounts of choline to prevent fatty liver and muscle damage. Eggs are an excellent source of this essential nutrient, providing nearly half the recommended daily supply per serving.
Two studies found that eating eggs for breakfast can lead to significant weight loss and improved energy levels. Additionally, eggs are an excellent source of choline, essential for brain function and development, and may help close the nutrient consumption gap among pregnant women and older adults.
The L'Oréal-UNESCO Award For Women in Science recognizes five outstanding female researchers, including Dr. Mildred Dresselhaus, who pioneered carbon nanotube research at MIT's School of Engineering. The award honors their contributions to various fields, including medicinal chemistry and bio-medical applications.
The International AIDS Vaccine Initiative proposes new scientific and policy initiatives to accelerate AIDS vaccine development, fostering capacity building in developing countries. The Blueprint highlights the need for a dynamic global research and development program with clear spending targets and equitable financial burden-sharing.
The L'Oréal USA Fellowships for Women In Science program recognizes young women in groundbreaking research, focusing on cell biology, organic chemistry, conservation, optics, and cellular biophysics. The program aims to support their careers and build networks, encouraging a diverse range of scientific advancements.
The study demonstrated a statistically significant benefit of FOLFIRI in patients with metastatic colorectal cancer, improving progression-free survival and overall survival. Adding bevacizumab to FOLFIRI also showed improved outcomes, with a higher percentage of patients alive after one year.
Early breast cancer patients switching from tamoxifen to Aromasin experience a 17% lower chance of dying and a 25% lower risk of breast cancer recurrence. The study's findings also suggest long-term safety benefits, with no clinically meaningful changes in the side effect profile.
A phase 3 clinical study found that nearly half of patients with advanced illness experienced laxation within four hours of receiving methylnaltrexone, and over 70% responded by the end of the first week. The treatment also showed no diminishment of analgesia due to medication.
A recent study conducted by the UCLA School of Medicine found that testosterone replacement therapy does not negatively affect the prostate or its tissues in hypogonadal men. The six-month trial involved 41 men with low testosterone levels and showed no changes in prostate tissue, PSA, or DHT levels.
Astellas Pharma US, Inc. has been recognized by the American Urological Association for its continued support of education and research initiatives in urology. The company's commitment to improving urologic care through innovative pharmaceutical products is being acknowledged by the AUA.
A study found that adults and teens who eat beans have lower body weights, smaller waist sizes, and higher fiber intake than those who don't eat beans. Adult bean eaters also consume less total and saturated fat, reducing their risk of obesity by 22%.
The CYPHER stent demonstrated significant lower rates of target vessel failure, repeat revascularization, and major adverse cardiac events compared to bare metal stents. Patients at high-risk for re-blockage also showed improved outcomes without 'late catch-up' in restenosis.
The study demonstrates that carotid artery stenting with formalized training has outcomes comparable to the pivotal SAPPHIRE trial. Preliminary data indicates a low stroke rate of 3.6% at 30 days for patients treated by trained physicians.
Gliadel Wafer demonstrates long-term survival benefit for patients with high-grade malignant glioma, increasing median survival to 13.9 months from 11.6 months. The treatment also shows a significant reduction in risk of death over the study period, with a 27% lower risk compared to placebo.
The L'ORÉAL-UNESCO awards recognize pioneering work in immunology, molecular pathology, and genetic disorders. The laureates will receive a $100K prize and international recognition for their contributions to human health.
The CYPHER Stent showed reduced restenosis and TLR rates compared to the Taxus stent. Exponential growth in 2005, driven by positive trial results, solidified its position as the leading drug-eluting stent globally.
A new blood test has been developed to identify individuals at high risk for ischemic stroke in middle-aged adults. The PLAC test measures Lp-PLA2 and CRP levels, finding an 11-fold increased risk of stroke associated with elevated lipoprotein-associated phospholipase A2 and C-Reactive Protein.
A Lancet study found that Pfizer's Vfend is an effective alternative to a two-drug candidemia regimen, with comparable efficacy but fewer serious side effects. The treatment was found to be more tolerable, particularly in reducing renal toxicity and visual disturbances.
A retrospective analysis of patients with invasive aspergillosis showed that those who initially received Pfizer's antifungal agent VFEND had better survival rates and were less likely to need salvage therapy than those on amphotericin B. The study found that patients who started on VFEND also had higher success rates in switching to o...
A new study found that drug-eluting stents like CYPHER are cheaper than open-heart surgery, saving patients and the healthcare system $6,487 on average over a year. The research also shows improved patient outcomes with stent treatment.
A meta-analysis of seven head-to-head drug-eluting stent trials found that the CYPHER Stent reduces the need for re-treatment by about 30% compared to Taxus Stent-treated patients, regardless of patient and lesion types. The CYPHER Stent's strong clinical performance is established through rigorous analysis.
The PRISON II trial found that CYPHER Stent patients experienced lower rates of in-stent restenosis and target vessel failure compared to bare metal stents. This study provides new clinical evidence for the use of CYPHER Stent in complex patient cases.
The SAPPHIRE and US carotid feasibility trials demonstrated the durability of carotid stenting, showing low incidence of stroke and comparable target lesion revascularization (TLR) rates between CAS and CEA. Emboli protection with ANGIOGUARD also showed effectiveness in preventing major strokes during carotid stenting.
A large multicenter randomized study involving 384 patients found the CYPHER Stent to have a superior safety profile compared to intravascular brachytherapy. The study showed lower incidence of target vessel failure and major adverse cardiac events with the CYPHER Stent at nine-month follow-up.
A retrospective study found that patients treated with oral ZYVOX had lower healthcare resource utilization and costs compared to those treated with vancomycin. The average total cost per patient was $4,630 less for ZYVOX patients.
A phase III study found that GARDASIL vaccine prevented 100% of high-grade cervical pre-cancers and non-invasive cancer cases in women infected with HPV types 16 and 18. The vaccine reduced the risk of developing these cancers by 97%, significantly reducing cervical cancer-related deaths worldwide.
A protein-rich diet combined with exercise leads to greater weight loss and fat reduction compared to a high-carbohydrate, lower-protein diet. This study found that dieters on the protein-rich diet lost almost 100% of their weight in fat, while those on the low-protein diet lost 25-30% of their weight as muscle.
The need for consensus on IVIG dosing and frequency arises as its use expands, with infusion nurses playing a crucial role in achieving best results from therapy. The article highlights the importance of developing guidelines that maximize patient benefit and minimize risk, given the unique response to different IVIG products.
Researchers discover KDI tri-peptide can block glutamate's damage in degenerative brain diseases, potentially leading to paralysis reversal and nerve regeneration. Human clinical trials expected to begin next year, with no toxic side effects seen so far.
A cross-sectional study of 2,162 men found that 38.7% had low testosterone levels and 23% had a history of diabetes. Men with diabetes and low T were 2.09 times more likely to have hypogonadism, a condition characterized by low testosterone production.