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Massachusetts Institute of Technology


Team probes mysteries of oceanic bacteria

A team of MIT researchers has devised a new method to analyze gene expression in complex microbial populations, providing insights into the role of oceanic bacteria in regulating Earth's natural cycles. The technique has yielded surprising discoveries, including the identification of previously unknown bacterial genes and their functions.

SourceMassachusetts Institute of Technology·JournalProceedings of the National Academy of Sciences·DateMar 3, 2008

MIT explains spread of 1918 flu

Researchers discovered two mutations in the H1N1 avian flu virus's hemagglutinin molecule enable it to bind tightly to human upper respiratory tract receptors. This binding affinity is crucial for viral transmission and explains why certain strains are more infectious than others.

SourceMassachusetts Institute of Technology·JournalProceedings of the National Academy of Sciences·DateFeb 18, 2008

Team IDs weakness in anthrax bacteria

Researchers have discovered a weakness in the defenses of the anthrax bacterium that could be exploited to produce new antibiotics. Nitric oxide is a critical part of Bacillus anthracis's defense against the immune response, and disrupting this system could make it vulnerable to attack by macrophages.

SourceMassachusetts Institute of Technology·JournalProceedings of the National Academy of Sciences·DateJan 24, 2008

MIT reports new twist in microRNA biology

Researchers identified two microRNA pairs in fruit fly and eight more in mouse where both DNA strands encode RNA products, which fold into hairpins that are processed into mature microRNAs. This discovery builds on earlier findings about microRNA regulation using computational tools to investigate genomes of multiple species.

SourceMassachusetts Institute of Technology·JournalGenes & Development·DateJan 11, 2008

MIT sculpts 3-D particles with light

Researchers at MIT have developed a method to create three-dimensional microparticles using ultraviolet light, offering unprecedented control over size, shape, and texture. The particles can be designed with specific chemical properties, such as porosity, making them suitable for use in medical diagnostics and tissue engineering.

SourceMassachusetts Institute of Technology·JournalAngewandte Chemie·DateDec 3, 2007