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Massachusetts Institute of Technology


MIT reports new twist in microRNA biology

Researchers identified two microRNA pairs in fruit fly and eight more in mouse where both DNA strands encode RNA products, which fold into hairpins that are processed into mature microRNAs. This discovery builds on earlier findings about microRNA regulation using computational tools to investigate genomes of multiple species.

SourceMassachusetts Institute of Technology·JournalGenes & Development·DateJan 11, 2008

MIT sculpts 3-D particles with light

Researchers at MIT have developed a method to create three-dimensional microparticles using ultraviolet light, offering unprecedented control over size, shape, and texture. The particles can be designed with specific chemical properties, such as porosity, making them suitable for use in medical diagnostics and tissue engineering.

SourceMassachusetts Institute of Technology·JournalAngewandte Chemie·DateDec 3, 2007

MIT gel changes color on demand

The team developed a structured gel with tunable optical properties that can rapidly change color in fractions of a second. The gel's color shift is limited to one dimension due to its one-dimensional periodic stack structure, resulting in a dramatic improvement over earlier color-changing gels.

SourceMassachusetts Institute of Technology·JournalNature Materials·DateOct 21, 2007

MIT IDs binocular vision gene

Researchers from the Picower Institute at MIT have identified the gene Ten_m3 as crucial for creating matched projections from both eyes in the brain. In mice with this gene knocked out, visual deficits persisted even when one eye was covered, but blocking the output of one eye restored vision.

SourceMassachusetts Institute of Technology·JournalPLOS Biology·DateSep 13, 2007

MIT creates 3-D images of living cell

Researchers at MIT have developed a technique to create 3D images of living cells, revealing internal structures and enabling the study of cellular function in its native state. The method uses interferometry and refractive index properties, producing high-resolution images with resolutions as low as 150 nanometers.

SourceMassachusetts Institute of Technology·JournalNature Methods·DateAug 12, 2007

MIT IDs link between brain tumor proteins

MIT scientists have discovered a connection between two proteins found in brain tumors that could help treat glioblastoma multiforme (GBM), the most aggressive form of brain cancer. Attacking both EGFRvIII and c-Met simultaneously is more effective than targeting either protein alone, offering new hope for treating this deadly disease.

SourceMassachusetts Institute of Technology·JournalProceedings of the National Academy of Sciences·DateJul 19, 2007

MIT IDs mechanism behind fear

Researchers at MIT's Picower Institute have discovered a molecular mechanism that governs the formation of fears stemming from traumatic events. Inhibiting a kinase called Cdk5 facilitates the extinction of fear, while increased activity persists fear learned in a particular context.

SourceMassachusetts Institute of Technology·JournalNature Neuroscience·DateJul 15, 2007