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Mayo Clinic


Mayo Clinic study finds prophylactic mastectomy reduces breast cancer risk in highest-risk group of women — carriers of BRCA1 and BRCA2 mutations

A Mayo Clinic study found that prophylactic mastectomy reduced the risk of breast cancer in women with BRCA1 and BRCA2 mutations by 89.5% to 100%. The study followed 26 high-risk women for 13.4 years without developing breast cancer, despite predicted risks of 6-9 cases.

SourceMayo Clinic·JournalJNCI Journal of the National Cancer Institute·DateNov 6, 2001

New study from the United Nations Food and Agricultural Organization and Mayo Clinic sets the stage for future nutritional research throughout the world

A new study from the United Nations Food and Agricultural Organization and Mayo Clinic found that women in western Africa need more energy than men based on their work burden. The research determined that women worked two to three hours more per day than men, resulting in a 30% increase in energy needs.

SourceMayo Clinic·JournalScience·DateOct 25, 2001

Study finds older patients benefit as much from chemotherapy after surgery for colon cancer as younger patients

A new study published in New England Journal of Medicine found that age alone should not determine whether an older patient is offered chemotherapy after surgery for treatment of stage II and III colon cancer. The study showed a significant reduction in death risk and improved survival rates among patients over 70 with the disease.

SourceMayo Clinic·JournalNew England Journal of Medicine·DateOct 10, 2001

Tobacco-industry sponsored research misled

Researchers from Mayo Clinic and University of Minnesota found that tobacco industry sponsored research misled the public about the health risks of secondhand smoke. The study analyzed over 1.5 million pages of internal documents, revealing a campaign by the industry to deny health risks and preserve profits.

SourceMayo Clinic·JournalAmerican Journal of Public Health·DateSep 27, 2001

August news briefs

A Mayo Clinic study published in Cancer journal reveals that daily alcohol consumption by women whose mothers, sisters or daughters have breast cancer may increase their risk for getting the cancer. The study found an increased risk among first-degree relatives of women with breast cancer, but less evidence among second-degree relatives.

SourceMayo Clinic·JournalCancer·DateAug 10, 2001

New Mayo Clinic study questions benefit of smoking reduction

A new Mayo Clinic study found that heavy smokers who cut back their smoking rate may not see health benefits, contradicting the assumption that reducing smoking can lead to better health. The study of 23 heavy smokers over nine weeks showed mixed results, with some biomarkers improving and others worsening.

SourceMayo Clinic·JournalNicotine & Tobacco Research·DateDec 21, 2000

In an animal study, Mayo clinic researchers identify ways to delay and increase survival from Lou Gehrig’s disease

Researchers discovered a modified antioxidant enzyme that delayed onset and increased survival of mice with familial amyotrophic lateral sclerosis (ALS or Lou Gehrig's disease). The study found that the polyamine-modified catalase better penetrated the blood-brain barrier, reducing levels of hydrogen peroxide and nitric oxide.

SourceMayo Clinic·JournalAnnals of Neurology·DateDec 17, 2000

Less radical surgery for kidney cancer is equally effective to radical alternativve and less likely to cause failure to other kidney

A Mayo Clinic study finds that less radical surgery for kidney cancer is equally effective to radical alternative and less likely to cause failure in the second kidney. Long-term survival rates between the two procedures were identical, but patients undergoing less radical surgery had a lower risk of developing renal failure.

SourceMayo Clinic·JournalMayo Clinic Proceedings·DateDec 13, 2000

The jury's still out on soy

The Mayo Clinic report concludes that the available data are insufficient to draw definitive conclusions about the use of soy isoflavones as an alternative to estrogen for hormone replacement in postmenopausal women. Randomized, placebo-controlled clinical trials are necessary to address the potential benefits and risks of isoflavone use.

SourceMayo Clinic·JournalMayo Clinic Proceedings·DateNov 15, 2000

Mayo Clinic researchers develop new antibody

Mayo Clinic researchers have developed a new antibody test to help diagnose autonomic disorders caused by the immune system. The test detects antibodies that bind to an important protein on autonomic nerve cells, helping physicians evaluate patients with autonomic failure.

SourceMayo Clinic·JournalNew England Journal of Medicine·DateSep 19, 2000

Blood pressure during sleep may be important too

A Mayo Clinic study found that blood pressure levels differ equally between day and night, potentially increasing the risk of heart disease and stroke. The researchers monitored 240 healthy people for 20 consecutive hours, revealing significant variations in blood pressure during sleep.

SourceMayo Clinic·JournalAmerican Journal of Hypertension·DateMar 8, 2000

Encouraging results reported for new breast cancer therapy

A new treatment combination of paclitaxel and carboplatin has shown encouraging results in a clinical trial, achieving a 62% response rate and a projected 72% one-year survival rate. The treatment, which is compatible with prior anthracycline therapy, offers additional benefits for women with metastatic breast cancer.

SourceMayo Clinic·JournalCancer·DateFeb 7, 2000