According to the study, the nasal endoscopic approach was successful in treating cerebrospinal fluid rhinorrhea, with 92% of patients experiencing long-term success. The procedure involves using small cameras and monitors to operate with minimal trauma, reducing the risk of complications.
Researchers are using genetically engineered 'mighty mice' to study the relationship between muscle and bone health. They hope to find a way to build bone and avoid osteoporosis in young people. Early evidence suggests that exercise may not have as much of an impact on bone density as previously thought.
The green tea gum helps eliminate free radicals that can damage DNA and lead to cancer. It also protects healthy cells by targeting cancer cells for destruction.
Researchers at Medical College of Georgia have discovered a new category of multi-potent cells called VENT cells, which play a critical role in development and contribute to the formation of various human tissues. The discovery challenges long-held notions about what type of cells form specific types of tissue.
Researchers at Medical College of Georgia are using an animal model of cerebral palsy to identify the most effective way to transplant stem cells. They aim to determine whether transplanted stem cells work best when injected directly into the brain along with natural chemicals called chemokines.
A team of MCG students has discovered a vegetarian alternative to chicken liver for diagnostic imaging, utilizing Carborite Pancake Mix. The product's binding rate is 97-98%, comparable to that of chicken liver.
Researchers found that removing a diseased thyroid from under the arm provides a cosmetic incision and inconspicuous scars. This approach may become a new standard for thyroid surgery in the US as minimally invasive techniques gain popularity.
A new study suggests that a stroke-prevention strategy for kids pioneered at MCG is working. The program, which involves regular blood transfusions and screening using transcranial Doppler, has led to an 80% decline in strokes among California children with sickle cell disease.
Researchers have identified a way to exploit the body's natural protective mechanisms used by tumors to evade the immune system. By targeting an immunosuppressive enzyme called IDO, scientists may be able to create new cancer treatments that make tumors more vulnerable to the immune response.
Researchers found a natural mutation of the SUMO-4 gene, which regulates immune system activity, to be a major contributor to type 1 diabetes. The mutation increases the immune system's reactivity to environmental triggers, leading to an autoimmune response that attacks the patient's own tissue.
A new HPV vaccine study is underway in women aged 24-45 to prevent cervical cancer and genital warts. The quadrivalent vaccine protects against four common strains of human papillomavirus virus, including two that cause cervical cancer and two that cause genital warts.
Researchers at the Medical College of Georgia have identified a gene called Indy that plays a critical role in delivering energy to cells, which may contribute to aging. By altering the activity level of this gene, they found that tiny worms lived longer and were thinner, raising hopes for potential human benefits.
Researchers found three to four times more antibodies in Alzheimer's patients than healthy individuals, indicating a possible autoimmunity component to the disease. This discovery may lead to an early diagnostic test and more targeted treatments.
Researchers discovered that choroid plexus cells can stimulate stem cell production and release neurotrophic factors after a stroke, reducing damage in animal models. The study suggests potential for new therapy to supplement the natural healing response of this tissue.
A new study has found a significant link between caffeine consumption and increased blood pressure in black adolescents. Adolescents who drank the most caffeinated beverages had higher systolic pressures, with black adolescents showing a greater impact. The researchers suggest that further research is needed to explore this relationship.
Researchers investigate protein regulators of inflammation and hypertension, aiming to find direct cause-and-effect relationship between the two. The study could lead to new targets for treating high blood pressure, a major risk factor for heart disease.
A Medical College of Georgia study aims to identify specific protein markers in the blood that indicate how ovarian cancer responds to therapy. By analyzing changes in protein expression over time, researchers hope to develop a better understanding of the disease process and create more effective screening tests.
A study found that 156 inner-city black adolescents who practiced transcendental meditation twice daily for four months lowered their daytime blood pressures, with an average drop of 3.5 millimeters in systolic pressure and 3.4 millimeters in diastolic pressure.
A researcher is studying how diabetes affects ganglion cells and developing a potential treatment using sigma receptor ligands. The goal is to prevent ganglion cell death and the growth of new blood vessels that obstruct vision.
Researchers found that 9-11 attacks had a significant impact on black adolescents, with 28% feeling pessimistic about their future and 22% losing faith in government protection. The Iraq War study showed military youth experiencing higher blood pressures, heart rates, and anxiety symptoms.
SLC5A8 transporter enables the colon to absorb short-chain fatty acids, produced by bacteria fermenting plant cell walls, for energy. This finding supports eating vegetables to limit antibiotic use and promotes a healthy gut microbiome.
A new clinical study examines whether restoring good bacteria in intensive-care patients can help prevent infections. The study, led by Dr. Robert G. Martindale, aims to enroll 400 patients and assess the effectiveness of probiotics in reducing infections.
A recent study provides new hope for understanding autoimmune diseases like pemphigus foliaceus by identifying an inexpensive blood test that can detect antibodies and intervene to halt disease progression. Environmental factors, including mercury exposure, ultraviolet radiation, and female hormones, are also being investigated as pote...
Researchers at MCG are studying Campylobacter jejuni to understand its effects on the human body. They aim to develop a vaccine and improve prevention methods for this bacterial infection, which causes bloody diarrhea, fever, and abdominal pain in millions of Americans each year.
A national expert panel updated widely used criteria for potentially harmful medications in older adults. The 1997 Beers Criteria has identified 48 medications to avoid, including estrogen and Benadryl, due to increased risk of adverse drug events such as depression and bleeding.
Researchers at the Medical College of Georgia found that glycerin helps skin cells mature properly, which can aid in treating diseases like psoriasis and non-melanoma skin cancers. Glycerol was shown to produce a signal that directs normal skin cell maturation, and its absence may lead to hyper-proliferative, thick skin.
A study led by Dr. Lawrence C. Layman aims to identify genetic mutations contributing to delayed puberty, which may lead to better infertility treatment and birth control options. By analyzing the function of hundreds of genes, researchers hope to uncover potential treatments for this condition, which affects about 1% of the population.
A nicotine metabolite, cotinine, may improve memory and protect brain cells from diseases like Alzheimer's and Parkinson's. Cotinine also displays antipsychotic properties, potentially offering a safer alternative to existing therapies.
Researchers found that overweight boys experience greater increases in blood pressure during stress, but their ability to restore normal pressures is impaired. In contrast, overweight girls have a more effective natural mechanism for reducing blood pressure, which may be attributed to the effects of estrogen.
Researchers are studying the effects of low doses of radiation on zebrafish embryos to understand DNA damage and repair mechanisms. The study aims to determine the threshold for damage and whether certain genes and proteins can prevent or repair damage, with potential implications for human health.
The JAK2 enzyme plays a dual role, protecting brain cells from Alzheimer's disease and blocking cell death pathways. However, it also causes damage to blood vessels in diabetics, leading to hypertension, kidney failure, and other age-related diseases.
Researchers at Medical College of Georgia discover a molecule, HLA-G, that helps keep immune cells immature and tolerant during pregnancy. This mechanism may be replicated to preserve transplanted organs and reduce rejection rates.
A major axis within bone cells regulates bone production and loss, providing a potential new target for treating debilitating osteoporosis. Local regulation of bone mass is now believed to occur primarily in the bone, not in the brain as previously thought.
A collaborative study between UGA and MCG investigated the cognitive effects of long-term use of newer schizophrenia drugs. The researchers found that while atypical antipsychotics cause fewer problems with movement disorders, their long-term impact on cognitive function is still unclear.
Researchers investigate how excess fat contributes to hypertension by increasing blood volume, as opposed to constricting it. Studies show impaired sodium handling mechanisms lead to prolonged elevated pressures in obese individuals.
Scientists have discovered that cells can adapt to survive without oxygen, a key finding that could lead to new treatments for cancer, heart attack, and stroke. Researchers are tracing the signaling pathways for cell injury and death, with hopes of identifying therapeutic tools to switch cellular behavior.
Researchers have identified a small subset of dendritic cells that can suppress T-cell responses, potentially treating tumors and autoimmune diseases. Experimental immunosuppressive agents are being explored for their ability to target this subset, offering new hope for patients with transplanted organs and autoimmune conditions.
Scientists have identified a signal that triggers half of the stem cells in the developing brain to commit suicide at a certain point in development. This finding may one day help victims of devastating brain diseases such as Alzheimer's, Parkinson's, and stroke by understanding cell death and potential recovery mechanisms.
Scientists have identified a new cell type, VENT cells, that migrate to the developing inner ear and mix with epidermal cells, contributing to the formation of complex tissues. The discovery, made by Dr. Paul Sohal, could explain how single cells give rise to distinct systems.
A recent study by Dr. Wieslaw E. Kozak found that nitric oxide has a distinct role in fever regulation, involving three different enzymes: neuronal nitric oxide synthase, inducible nitric oxide synthase, and endothelial nitric oxide synthase. The researchers used knockout mice to study the impact of these enzymes on fever response.
Researchers have found that green tea polyphenol EGCG can reactivate dying skin cells, accelerating their growth and differentiation. This could lead to new treatments for skin diseases and wounds, such as aphthous ulcers and psoriasis.
Researchers have found that red blood cells cannot repair tears in their surfaces due to the lack of internal membranes, confirming a decade-old hypothesis. In contrast, muscle cells can rapidly repair tears by sealing them with a large internal membrane.
A study published in Pediatrics found that many male residents don't perform regular testicular self-exams and teach the technique to their patients. The most common reason cited was a lack of time, with only 29% of residents performing monthly self-exams.
A researcher is studying how tumors pirate angiogenesis, the formation of new blood vessels, to survive. Dr. Motamed focuses on protein SPARC, which regulates growth factors and has multiple roles in cancer and new blood vessel formation.
A researcher has found a new cell type, VENT cells, that can give rise to all four major types of human tissue. This discovery challenges the existing understanding of human development and opens up new avenues for research into diseases such as Hirschsprung's disease and esophageal reflux disease.
A gene involved in forming blood vessels has been identified as a key player in DiGeorge syndrome, a chromosomal abnormality causing devastating birth defects. The study found that abnormalities in VEGF lead to the syndrome, which affects the heart, thymus, parathyroid gland, and mental retardation.
Researchers investigate how pregnancy affects medication levels in the blood, suggesting that placenta's organic cation transporter plays a crucial role. The study aims to inform safe dosing practices for pregnant women taking common medications, potentially improving treatment outcomes and reducing risks.
A $3.3 million NIH-funded grant will test whether changing the afternoon environment can increase physical activity, improve diets, and reduce body fat in third-graders.
Researchers have found that delta opioid peptide may help protect brain cells from the ravages of Parkinson's disease by inducing a state of suspended animation. The compound was shown to reduce brain damage and neurological deficits in animal models of stroke, suggesting potential benefits for patients.
A study found that children exposed to dogs and cats in the home have a significantly reduced risk of developing common allergies, with exposure levels reducing allergy rates by up to 45%. The research suggests that early exposure to endotoxins from pets may help the immune system develop a different response, making it less likely for...