Women's stroke symptoms differ from men's, often non-traditional and less specific. The study found that women were more likely to report non-traditional symptoms like pain and changes in consciousness.
Researchers have discovered a novel compound that kills bad immune cells while leaving healthy ones intact, offering hope for safer and more effective treatments for lupus. The compound, Bz-423, targets a protein in immune cells' mitochondria, showing promise in treating autoimmune diseases and potentially some types of cancer.
Researchers found that EZH2 expression was significantly higher in metastatic prostate cancer tissue compared to localized prostate cancer. A future test for high levels of EZH2 protein could serve as a red flag for physicians to identify men with the most aggressive form of the disease.
A recent study published in the Journal of the American Medical Association found that patients taking losartan had a significantly lower combined rate of cardiovascular death, stroke, and heart attack compared to those taking atenolol. The results showed a 40% reduction in stroke risk and a lower overall mortality rate.
A genetic mutation common among Ashkenazi Jews can double the risk of colorectal cancer. Researchers discovered this relationship through an international study analyzing DNA from nearly 3,100 individuals.
Researchers discovered tetrathiomolybdate (TM) inhibits tumor angiogenesis by reducing copper levels and blocking NFkB signaling pathway. TM suppressed tumor growth in mice with aggressive breast cancer, prevented blood vessel formation, and induced disease-free survival.
Researchers have made significant strides in artificial liver technology, with 20 patients using the albumin dialysis approach in a phase I trial. The system has shown promise in reducing blood toxins and reversing coma and shock, offering hope to those waiting for liver transplants.
Researchers have identified a new human hearing loss gene, TMIE, in deaf mice, which may lead to the development of a screening test and therapy for families affected by inherited hearing loss. The discovery brings scientists closer to understanding the intricate choreography of genes and proteins involved in human hearing development.
The Center for Molecular Imaging will combine cutting-edge imaging technologies with new knowledge about genes and proteins to develop ways of seeing cancer as it begins, grows, and is killed. The laboratory discoveries made by its scientists could accelerate everything from diagnosis to the development of future medications.
Researchers have discovered stem cells in the adult peripheral nervous system, which can persist into adulthood and give rise to thousands of neurons, glial cells, and smooth muscle cells. This finding has significant implications for understanding the development and repair of the peripheral nervous system.
Researchers have discovered that LINE-1 elements, which make up 17% of human DNA, can cause broad-spectrum mutations by deleting genetic material. In cultured human cancer cells, these elements can delete large segments of DNA, including regions as big as the BRCA1 gene.
Researchers at Michigan Medicine have discovered a new predictive marker, HIP1, associated with an increased risk of developing prostate and colon cancer. HIP1 levels were found to rise significantly in tumor cells, making it a potential target for therapy.
Researchers have discovered a gene associated with both macular degeneration and retinitis pigmentosa, two eye diseases affecting different segments of vision. The RPGR gene is linked to early-onset macular degeneration primarily affecting males.
A genetic mutation in the NOG gene causes autosomal dominant stapes ankylosis, a rare hearing loss syndrome with similar symptoms to otosclerosis. The syndrome is characterized by skeletal abnormalities and may require different treatment options.
The U-M Depression Center will expand outreach activities, automate treatment reporting, and coordinate care through trained specialists to improve depression treatment. The gift also enables the development of strategies for improving treatment adherence, a key factor in successful treatment outcomes.
Researchers will use tiny devices called nanosensors that can detect early signs of radiation-induced cell damage. The sensors, which pass easily through blood membranes, aim to avoid problems with current implantable sensors and eliminate blood sampling.
A team of researchers has established the first-ever gene profile of the aging human retina, revealing expression changes in genes involved in stress response and energy metabolism. The study's findings may help scientists understand how age predisposes individuals to age-related diseases such as AMD.
The U-M artificial lung has improved blood flow and reduced risk of clotting, showing encouraging results in sheep tests. The device could potentially bridge lung disease patients to transplant, reducing the average wait time from two years.
A study by researchers at Michigan Medicine found that nearly 38% of top-ranked US hospitals have fast-food franchises on their premises. The authors express concern that this serves a contradictory message to health promotion and may contribute to rising obesity rates in the US.
A new brain-scan study confirms fibromyalgia patients do experience severe pain, with measurable pain signals in their brains. The study uses fMRI scans to identify areas of the brain most active during pain, providing a road map for future research on the disease.
Researchers at U-M have discovered that inflammatory cytokines are the primary cause of graft-versus-host disease, which can be prevented by neutralizing these proteins. The study's findings offer new hope for patients undergoing bone marrow transplants, with human clinical trials currently underway.
A study by Michigan Medicine researchers found that 11% of doctors are willing to misrepresent patient information to obtain HMO approval for surgery or additional procedures. The 'hassle factor' plays a significant role in this behavior, with more physicians willing to deceive if the appeal process is longer or more burdensome.
A study by Michigan Medicine found that ER doctors can safely give stroke clot-busters, but patients need to reach the ER quickly. The study showed a complication rate similar to dedicated stroke teams, with 7% serious bleeding complications.
Scientists discovered that some human LINE-1 elements, known as junk DNA, can jump into chromosomes with broken strands and repair the damage. This finding raises questions about the potential benefits of these ancient genetic elements to human cells.
Researchers found that while Medicaid kids use the ER for non-urgent care more frequently than expected, a shift to managed care has actually reduced these instances. The studies also revealed that nearly half of parents' decisions to visit the ER were logical, based on their child's condition and available resources.
Historical evidence suggests that smallpox vaccination poses significant risks to certain populations, including children under one year old and those with compromised immune systems. Researchers estimate that 25% of the US population would need to be excluded from a vaccination campaign due to high-risk factors.
Researchers found that immunizing 50-75% of Americans aged 1-30 could save hundreds of lives compared to ring vaccination alone. The study suggests mass vaccination campaigns targeting young people may be cost-effective in preventing deaths from a potential smallpox attack.
A large randomized controlled study of e-mail communication between physicians and patients found that messages from patients were appropriate and needed by doctors. Patients sent an average of 49 messages per 100 scheduled visits, but the sharp increase didn't lead to a corresponding drop in calls or no-shows.
A study by Michigan Medicine researchers found that Katie Couric's 2000 colonoscopy on-air campaign significantly increased colon cancer screenings, with a 19% rise and sustained increases for 40 weeks. The 'Couric Effect' suggests celebrity influence can drive public behavior change.
A test to detect the RhoC protein has shown promising early results, detecting invasive cancers with high specificity and identifying tiny tumors that have already metastasized. The study aims to identify early-stage cancer that could be vulnerable to aggressive treatment, potentially leading to improved patient outcomes.
Scientists at Michigan Medicine have discovered that leptin is linked to blood clot formation, particularly in obese individuals. Knowing how to block this interaction could help prevent heart attacks and strokes.
Researchers at the University of Michigan have identified a gene, AMACR, which triggers production of a specific enzyme involved in fat metabolism. The protein is detected in over 95% of localized prostate cancer cells and shows high sensitivity and selectivity ratings for diagnostic purposes.
A study of 145 heart patients found that 74% used complementary and alternative medicine (CAM) therapy, with 60% using supplements or mind-body techniques. Many patients took prescription medications and CAM substances together, posing a risk of bleeding problems, including gastrointestinal bleeding or surgical complications.
A Michigan Medicine-led study has successfully improved the odds that patients receive life-saving treatments after a heart attack. The study, GAP (Guidelines Applied in Practice), used reminders, checklists, and educational materials to boost adherence to American College of Cardiology guidelines. As a result, hospitals saw significan...
A new study reveals a strong link between children's sleep problems and behavioral issues like hyperactivity and inattention. The research, published in the journal Pediatrics, found that children who snore often are nearly twice as likely to have attention and hyperactivity problems.
University of Michigan scientists have identified a protective mechanism that allows anthrax spores to remain dormant in soil for decades. The study found that germination requires the coordinated activity of multiple genes, receptor proteins, and amino acids in two simultaneous signaling pathways.
Researchers found that neural stem cells migrate to injured brain areas in response to acute brain injuries, such as strokes. This self-repair mechanism could potentially lead to new treatments for brain-related disorders.
A study of Maya children in the US found nearly half are overweight and 42% are obese, with TV and computer gaming linked to a higher risk. The disparity is attributed to American acculturation and socioeconomic factors, highlighting the need for targeted interventions.
The University of Michigan Medical School is addressing mounting clinical and economic pressures through its Innovations in Medical Education program. The four-part mission focuses on improving teaching in medical education, with research documenting increased productivity in publication and teaching effectiveness.
Researchers argue that English should be the primary language for space travelers due to its international significance and potential for genetic diversity. Despite this, changes in vocabulary may occur during the journey, particularly with new words being coined and old ones falling out of use.
The U-M Medical School is developing an interdisciplinary CAM curriculum, integrating theory, evidence, and practice to enhance learning. The program aims to increase medical students' knowledge of CAM, promoting a deeper understanding of the healing relationship between physician and patient.
Researchers found that inhibiting acid production made stomachs more vulnerable to bacterial invasion and gastritis. The study suggests that antibiotics are the best way to kill bacteria causing gastritis and eliminate inflammation. Inhibiting acid production can actually trigger an inflammatory response, making gastritis worse.
A recent study found that most popular melanoma web sites had incomplete facts about the disease, with around one in eight sites having inaccuracies. The study suggests that Web users should be cautious when searching for health information online and guide themselves toward reputable sources.
A new study suggests that smaller hospitals can perform heart bypass surgeries with similar outcomes to high-volume hospitals for low-risk patients. Moderate- and high-risk patients, however, should still seek major medical centers with high-bypass volumes to minimize mortality risk.
Pediatricians and family doctors are concerned about the high cost of new vaccines, insurance delays, and unequal access to these life-saving shots. The survey found that many doctors are hesitant to recommend the pneumococcal conjugate vaccine due to its financial burden.
A survey of over 400 doctors found that nearly a third would assist with lethal injections, highlighting the need for education on ethical guidelines and professional obligations. The study's authors warn that physicians' personal opinions on capital punishment may not align with their professional duties.
Researchers identified a mutated WFS1 gene responsible for low-frequency sensorineural hearing loss, which can lead to severe hearing aids requirements. The discovery may be common in the general population and could connect with other conditions like Meniere's Disease.
A study by Michigan Medicine researchers found that high oxygen levels can be toxic to stem cells, converting muscle cells into fat cells. This discovery has important clinical implications for the treatment of obesity and diabetes, as it may be related to aging and oxidative stress conditions.
Researchers have made a breakthrough discovery about the development of rod and cone photoreceptors, the light-sensitive cells in the retina that initiate vision. The study found that the retinal protein Nrl acts as a 'molecular switch,' signaling cells to develop into rods rather than cones.
Scientists have found a gene responsible for a rare form of hereditary spastic paraplegia, a condition that slowly robs children of their ability to walk. The discovery has opened the door to better diagnosis and treatment of the disorder, as well as insights into other spinal cord problems.