Researchers are investigating the correlation between a fading sense of smell and the onset of Parkinson's disease. The study, which draws from research demonstrating that first-degree family members have a slight increase in risk, will monitor relatives 50 years or older for early detection.
A recent study published in Academic Emergency Medicine found that using a 64-slice CT scanner to evaluate low-risk chest pain patients in the emergency room is more cost-effective than current standard of care. The study shows improved patient outcomes and reduced costs by avoiding overnight stays in observation units and cardiac stre...
A recent study led by Northwestern Memorial physician Virginia Kaklamani suggests that variations of the adiponectin gene may increase a woman's risk of developing breast cancer. This discovery could lead to the development of a genetic testing model to predict breast cancer risk more accurately.
Researchers are enrolling patients in a new study that transplants stem cells from a kidney donor's bone marrow into the recipient, with the goal of gradually eliminating the need for antirejection drugs. The study aims to improve post-transplant quality of life for recipients.
A recent study by Northwestern researcher Nalini Rajamannan reveals that bone growth, rather than wear and tear, is the primary cause of heart valve disease. This active process can be treated with medications similar to those used for coronary artery disease, offering new options for prevention and treatment.
The BRITE-MD trial aims to determine the accuracy of technology in predicting patient response to antidepressants, which could lead to faster recovery times. Preliminary analysis suggests high accuracy rates, but the study is currently recruiting participants.
A new clinical trial at Northwestern Memorial Hospital aims to evaluate the effectiveness of combining chemotherapy and radiation therapy with Avastin in reducing tumor size and increasing survival rates. The two-year study will enroll 40 participants with localized pancreatic cancer.
A study published by Northwestern Memorial HealthCare found that high-dose chemotherapy and autologous stem cell transplant can result in disease remission and improvement or salvage of residual organ function in the majority of patients with life-threatening lupus. The treatment's lower toxicity rate compared to previous studies may b...
A four-month study found that art therapy sessions improved eight out of nine symptoms in cancer patients, with significant reductions in pain, tiredness, and anxiety. Patients reported feeling energized and benefited from the creative process as a form of expression.
Researchers identified 17 cases of hypersensitivity reactions caused by drug-eluting stents, with symptoms including rash and difficulty breathing. The study concludes that the polymer coating on the stent is the most probable cause of these reactions.
Researchers followed nearly 6,000 women with metabolic syndrome over nine years, finding that cardiorespiratory fitness reduced overall deaths and heart disease-specific deaths to rates similar to those without the condition. Higher levels of cardiorespiratory fitness were associated with lower risk factors and improved heart health.
A new study estimates that S. aureus infections cause an average of 292,045 hospital stays per year, resulting in 3 times longer stays, triple the total charges, and five times higher risk of in-hospital death compared to non-infected patients. The study also found that antibiotic-resistant strains are becoming increasingly common.
Researchers developed a nomogram for women's exercise capacity based on age and stress test results, providing an accurate assessment of mortality risk. The study found that using the men's nomogram in women resulted in false positives, highlighting the need for personalized fitness assessments.
A new study suggests that ICD therapy can be beneficial for patients with recently diagnosed cardiomyopathy, reducing overall mortality risk. The findings support earlier implantation of ICDs in this patient population.
A Northwestern Memorial HealthCare study identified a gene variant TGFBR1*6A associated with a high risk of colorectal cancer. The variant was found to be more prevalent among patients without a mutation in other genes, suggesting its potent contribution to familial cases.
Researchers discovered that TGFBR1*6A gene variants significantly increase breast cancer risk in women over 50, with a 69% higher risk for those with low TGF-beta activity levels. The findings may help predict breast cancer risk in a large subset of the population and inform genetic testing options.
A Northwestern Memorial study finds that smart pump technology alone has limited potential to improve patient safety, but integrating it with EHRs and other technologies can significantly reduce errors. The hospital is developing a robust two-way communication system to verify physician orders in real-time.
A recent study presented at ACC Scientific Sessions found that even minor decreases in serum sodium levels significantly impact mortality rates among heart failure patients. Improving sodium levels during hospitalization was associated with improved outcomes and reduced mortality rates.
Researchers found that getting an epidural when the cervix is less than four centimeters dilated does not increase the cesarean delivery rate and provides significantly better pain relief. The study also showed shorter labors in the early epidural group compared to those who received standard narcotics.
A study confirms that implantable cardioverter-defibrillators (ICDs) are more effective in preventing sudden cardiac death than medical therapies for heart failure patients without coronary artery disease. The ICDs have shown a relative 35 percent decrease in overall mortality among these patients.
A study by Northwestern Memorial HealthCare found that non-cardiologists prescribed fewer medications to heart patients, including ACE inhibitors and beta-blockers, than cardiologists. The study suggests that cardiologists are more likely to order diagnostic tests without increasing hospital stays.
A 12-month study found that people and dogs lost an average of 11 pounds and 12 pounds respectively, with the combined dog/owner group showing higher participation rates. The program improved quality of life through increased exercise and strengthened human-animal bonds.
Researchers at Northwestern Memorial Hospital are testing a new Transcranial Magnetic Stimulation (TMS) treatment for major depression. The study aims to prove the effectiveness of TMS as a treatment alternative and compare its effects with placebo, with the goal of securing FDA clearance for clinical use.
A recent study found that nearly 82% of participants who gained 15 pounds or more over 15 years developed metabolic syndrome, a group of metabolic risk factors linked to increased heart disease risk. Weight stabilization is recommended as a key public health strategy.
A pilot study found that ductal lavage detected only half of the cancers in breasts with known cancer. The procedure's effectiveness is limited by poor agreement between cytologic analysis and microscopic results. Mammography and physical examination remain the most effective methods of early detection.
Visilizumab shows promise in treating severe ulcerative colitis by blocking processes that lead to colon inflammation and damage. The new therapy offers an alternative to invasive surgery for patients with severe UC.
A Northwestern Memorial Hospital study demonstrates that medication reconciliation reduces patient harm and is cost-effective. Pharmacists play a critical role in reconciling medication discrepancies, which can occur during patient transfers or discharge.
A study published in NEJM found that rapid rise in PSA levels prior to diagnosis is a stronger indicator of prostate cancer death than the actual PSA level. Early and annual testing are recommended for men with high PSA velocity to detect potential aggressiveness of cancers.
The Northwestern Memorial Hospital is testing a stomach 'pacemaker' system that reduces hunger and helps obese patients lose weight. The system, manufactured by Transneuronix, uses electrical stimulation to induce feelings of fullness.
Women are more likely to develop lung cancer, with longer survival rates compared to men. Estrogen signaling and hormonal factors may play a role in these differences.
A new study aims to determine if abciximab can improve function in patients with ischemic strokes up to six hours after onset. The treatment, which prevents blood platelets from forming clots, could provide a new approach for treating patients who wake up from sleep with a stroke.
A study by Northwestern Memorial Hospital suggests that CPOE systems with significant clinical decision support and pharmacist involvement can improve medication safety. However, the system's limitations in artificial intelligence mean that human oversight remains crucial to prevent prescribing errors.
A new study reveals that doctors offer tamoxifen primarily to women with higher risk profiles, despite those with lower side effect risks not being offered the drug. The research highlights a need for better educational strategies to help women make informed decisions about chemoprevention.
A Phase II study investigates the effectiveness of black cohosh and red clover in alleviating hot flashes and other menopausal symptoms. The study aims to provide an evidence-based response for women seeking alternatives to hormone replacement therapy.
A new study finds aromatase inhibitors can significantly reduce endometriosis severity and pain, offering a more effective treatment with fewer side effects. The treatment involves taking letrozole along with progestin for six months, resulting in improved symptoms and reduced estrogen production.
A study by Northwestern Memorial researchers found that taking baby aspirin or enteric-coated aspirin with Plavix provides a good blood-thinning effect, similar to full adult-dose aspirin. The results suggest that combining these medications can enhance the effectiveness of Plavix in reducing vascular events.
A recent study found that the TGFBR1*6A gene is associated with a 26% increase in cancer risk, particularly for breast, ovarian, and colon cancers. The study's findings suggest that genetic testing and counseling can help identify individuals at high risk and provide targeted prevention strategies.
The Northwestern Memorial Hospital is leading an international brain aneurysm study to confirm a familial link and identify specific genes responsible for the development of intracranial aneurysms. The goal is to prevent and treat aneurysms early, reducing premature mortality and morbidity associated with this type of stroke.
A Northwestern Memorial HealthCare-led study presents data demonstrating calcification in human tissue as the primary cause of aortic valve blockages. Statin therapy may delay progression and reduce need for surgical replacement.
Researchers found baby aspirin to be less effective in reducing the risk of stroke compared to adult and coated formulas. The study suggests that age and gender play a role in a person's response to aspirin, with women being more effective than men.