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PLOS


Taste sensors keep proteins in order in flies

A set of genes promoting sweet taste sensation also regulate protein management in flies, according to a new study. The finding suggests a connection between taste-related genes and disorders of protein aggregation.

SourcePLOS·JournalPLOS Biology·TypeExperimental study·DateJul 21, 2022

Anti-amyloid drugs and Alzheimer’s disease

A recent PLOS Biology study examines the limitations of current anti-amyloid therapies for Alzheimer's disease, suggesting abnormal microglial function and tau tangles as key mechanisms. The authors review clinical trial results and propose new strategies for treating the disease, bringing hope for a cure.

SourcePLOS·JournalPLOS Biology·TypeLiterature review·DateJul 21, 2022

Beliefs in conspiracy theories may not be increasing

Researchers found no statistically significant evidence that beliefs in conspiracy theories have increased over time, despite popular claims. The study suggests that some conspiracy theories are gaining popularity while others recede into history.

SourcePLOS·JournalPLOS ONE·TypeSurvey·DateJul 20, 2022

Research probes how people control unwanted thoughts

A new study published in PLOS Computational Biology suggests that proactively avoiding associations can help prevent the repetitive looping of unwanted thoughts. Researchers found that most people use reactive control, which can strengthen unwanted thoughts, but also discovered that preemptive control can partially mitigate this effect.

SourcePLOS·JournalPLOS Computational Biology·TypeExperimental study·DateJul 14, 2022

Moderate drinking linked to brain changes and cognitive decline

A study of almost 21,000 people found that moderate drinking is associated with higher iron levels in the brain and poorer cognitive function. Iron accumulation is a potential mechanism for alcohol-related cognitive decline, which can lead to Alzheimer's and Parkinson's diseases.

SourcePLOS·JournalPLOS Medicine·TypeObservational study·DateJul 14, 2022

When your older sibling chooses to stay in education for longer, so do you: new study suggests nature and nurture combine to link siblings' educational attainment

A new study suggests that the relationship between siblings' educational outcomes is influenced by both genetic and environmental factors. The research found that individuals with older siblings are more likely to excel academically, highlighting the complex interplay between nature and nurture.

SourcePLOS·JournalPLOS Genetics·DateJul 7, 2022

Performance-related bonuses for family healthcare workers in Brazil can improve the quality of primary health care, especially in more deprived areas

A study in Brazil found that performance-related bonuses for family healthcare workers can significantly enhance the quality of primary health care, particularly in more disadvantaged regions. The analysis showed a notable difference in outcomes between areas with and without bonus incentives.

SourcePLOS·JournalPLOS Medicine·TypeObservational study·DateJul 7, 2022

Students without disabilities achieve the same academic results with or without classmates with disabilities in Poland, with implications for the future development of inclusive education

A Polish study found that students without disabilities achieve the same academic results when attending classes with students who have disabilities, with implications for inclusive education. The research suggests that the type of inclusion does not affect academic achievement.

SourcePLOS·JournalPLOS ONE·DateJul 6, 2022

Developmentally arrested IVF embryos can be coaxed to divide

A new study published in PLOS Biology found that IVF embryos often undergo genetic and metabolic changes that inhibit development. The researchers discovered that certain embryos enter a senescent-like state, but treating them with resveratrol can help overcome this arrest and promote further development.

SourcePLOS·JournalPLOS Biology·TypeExperimental study·DateJun 30, 2022

Underwater jars reveal Roman period winemaking practices

A multidisciplinary study of Roman period wine jars reveals the use of native grapes for wine production and foreign pine for waterproofing tar pitch. The analysis provides insight into the cultural practices of ancient winemakers in coastal Italy.

SourcePLOS·JournalPLOS ONE·TypeObservational study·DateJun 29, 2022

An engaging leadership style may boost employee engagement

A longitudinal study found that supervisors perceived as engaged leaders enhanced employee engagement via boosted personal psychological resources and team effectiveness. Engaged leaders also fostered a shared perception of available resources, leading to improved job performance.

SourcePLOS·JournalPLOS ONE·TypeSurvey·DateJun 29, 2022

Pollution exposure associated with multimorbidity risk

A new study found that fine particulate matter (PM2.5) exposure is associated with an increased risk of having a cluster of multiple chronic diseases, particularly cardio-metabolic and respiratory conditions. The analysis revealed four distinct multimorbidity clusters, with lower PM2.5 exposure linked to musculoskeletal conditions.

SourcePLOS·JournalPLOS Global Public Health·TypeSurvey·DateJun 29, 2022

College towns saw fewer COVID-19 cases when classes were held online and/or on-campus testing was conducted – suggesting regular tests could reduce future community infections

Researchers found that college towns experienced lower COVID-19 case rates when classes were held online or accompanied by regular on-campus testing. This suggests that implementing regular testing could help mitigate future community infections in these settings.

SourcePLOS·JournalPLOS Digital Health·TypeObservational study·DateJun 23, 2022

Hormones are linked with sleep apnea, snoring in postmenopausal women

A study published in PLOS ONE found an association between reduced estrogen and progesterone levels and increased risk of snoring and obstructive sleep apnea in postmenopausal women. Low estrogen levels were linked to a 19% decreased odds of snoring, while low progesterone levels were associated with a 9% decrease.

SourcePLOS·JournalPLOS ONE·TypeSurvey·DateJun 22, 2022

Uncovering links between grit and cognitive function

Researchers found that people with higher grit scores showed different patterns of cognitive performance, characterized as cautious control, but not necessarily enhanced cognitive ability. Grit was linked to low impulsivity and high mindfulness, related to self-regulation.

SourcePLOS·JournalPLOS ONE·TypeSurvey·DateJun 22, 2022

Language matters when describing weight loss goals

Researchers found that using analytical language when describing weight loss goals led to greater weight loss success and lower dropout rates. Analytical language, such as focusing on what's important and why, was associated with more weight loss and less program attrition.

SourcePLOS·JournalPLOS Digital Health·TypeObservational study·DateJun 16, 2022

Researchers develop a comprehensive atlas of disease mortality

Researchers have developed a comprehensive atlas of disease mortality, providing a resource to estimate reductions in life expectancy for various disorders. The study analyzed data from 7,378,598 people living in Denmark from 2000 to 2018 and generated a panel of epidemiological and mortality metrics.

SourcePLOS·JournalPLOS Medicine·TypeObservational study·DateJun 16, 2022

Red meat consumption may remain high in Finland despite consumer support for plant-based diets

A recent study found that while consumers in Finland express openness to shifting towards a plant-based diet, their purchasing trends reflect a strong preference for red meat. The researchers analyzed individualized purchase data of 29,437 customers and found that red & processed meat accounted for 63% of protein purchases, while plant...

SourcePLOS·JournalPLOS Sustainability and Transformation·TypeObservational study·DateJun 16, 2022

Dog-assisted interventions lead to lower stress levels in children

A new study published in PLOS ONE found that dog-assisted interventions can significantly reduce stress levels in elementary school children, both with and without special needs. The research used salivary cortisol levels to track the effects of dog interactions on stress levels, revealing a decrease in cortisol levels after dog sessions.

SourcePLOS·JournalPLOS ONE·TypeRandomized controlled/clinical trial·DateJun 15, 2022

Study reveals how epilepsy and migraine drug causes birth defects

A study reveals that valproic acid induces cellular senescence in neuroepithelial cells, leading to developmental defects such as spina bifida, facial alterations, and Autism Spectrum Disorder. The researchers found that a specific molecule, p19Arf, is responsible for this effect.

SourcePLOS·JournalPLOS Biology·TypeObservational study·DateJun 14, 2022

Preventing adverse birth outcomes could boost education, income

A new modeling study found that reducing excess prevalence of low birthweight, preterm birth, or small-for-gestational-age birth in low- and middle-income countries could lead to substantial long-term human capital gains. The study estimates potential gains of 20.3 million school years and $68.8 billion in lifetime income per birth coh...

SourcePLOS·JournalPLOS Global Public Health·TypeComputational simulation/modeling·DateJun 8, 2022