A recent US study found that hip resurfacing surgery is not suitable for all patients, particularly those over 55 or female. The procedure's success depends on a patient's age and gender due to differences in bone quality.
Researchers at Rush University Medical Center discovered that proton channels in basophils respond to agents triggering histamine release, with zinc inhibiting these currents. This finding points to a new approach to reduce the consequences of asthma and allergic reactions.
A new study found that testosterone predominance during menopause is associated with a higher prevalence of metabolic syndrome, which increases the risk of cardiovascular disease. The study suggests that testosterone may play a more significant role in cardiovascular risk than previously thought.
Difficulty sleeping and waking up early are more common in certain ethnic groups during menopause. The study found that Caucasian women were more likely to experience difficulty staying asleep, while Hispanic women were less likely to wake up frequently at night.
Researchers are investigating the effectiveness of dietary changes and complementary medicine to control inflammatory bowel diseases (IBD) flare-ups. The studies aim to find alternative treatments with fewer side effects, targeting stress reduction and gut bacteria balance.
Researchers at Rush University Medical Center present pre-clinical data on a CD26 Inhibitor that increases the efficiency and responsiveness of umbilical cord blood for bone marrow transplants. The technology may improve treatment outcomes for blood cancer patients who require stem cell transplantation.
A study by Rush University Medical Center found that the Z-plasty technique significantly improves nasal airflow and reduces recovery time compared to traditional open rhinoplasty. The minimally invasive procedure shows promise as an effective treatment option for patients with internal nasal valve collapse.
A study by Rush University Medical Center found that elderly patients with chronic illnesses who receive virtual care from a team of medical experts make fewer emergency room visits. This coordinated approach also improves patients' understanding of their medications and enhances communication between physicians.
A novel cell therapy using retinal pigment epithelial cells attached to gelatin bead microcarriers has shown promising results in patients with moderate to advanced Parkinson's disease. The therapy, Spheramine, has been well-tolerated and has improved symptoms such as tremor, rigidity, and balance issues for several years.
A new study finds that depression is a risk factor for Alzheimer's disease, rather than an early sign of its underlying pathology. The research, published in Archives of General Psychiatry, found no increase in depressive symptoms before the clinical diagnosis of Alzheimer's disease.
A recent study published in Nature Medicine found that fetal cells implanted in patients with Parkinson's disease can develop Lewy body pathology, a defining characteristic of the disease. The study suggests that cell replacement strategies for Parkinson's disease may not be effective in the long-term.
A new study by Rush University Medical Center found that women are significantly less likely to be treated with statins, aspirin, and beta-blockers for coronary artery disease compared to men. Despite similar prevalence of adverse drug reactions, the study suggests underutilization of medical therapies may contribute to this disparity.
A study published in the New England Journal of Medicine found that patients who underwent surgery for spinal stenosis showed significant improvement compared to those treated nonsurgically. After two years, 63% of surgical patients experienced a major improvement, while 29% of non-surgical patients reported similar results.
The Otho S.A. Sprague Memorial Institute has awarded Rush a $124,633 grant to support a first-of-its-kind patient-safety project using mediation to resolve disputes and prevent adverse events. The program aims to reduce future medical malpractice actions and improve quality care.
The Otho S.A. Sprague Memorial Institute has awarded Rush University Medical Center a grant to support a first-of-its-kind childhood obesity project. The 18-month pilot program aims to prevent childhood obesity by combining biomedical and psychosocial approaches, involving families and healthcare professionals.
A study by Rush University Medical Center found that half of patients receiving cerebrovascular stents did not adequately respond to clopidogrel. The researchers identified a significant association between older age and diabetes with platelet activity, suggesting these patients may require alternative approaches.
A study at Rush University Medical Center suggests that bubbles may regulate ion channel opening and closing, providing a vital piece of the molecular puzzle. This discovery has significant implications for treating diseases linked to malfunctioning ion channels, such as heart disease and cystic fibrosis.
A large clinical trial found that bevacizumab significantly prolongs progression-free survival for women with recurrent breast cancer when combined with chemotherapy. The study showed a doubling of delay in worsening of the disease and improved remission rates compared to chemotherapy alone.
Findings from two large clinical trials demonstrate significant improvement in patients with multiple myeloma who received Revlimid, an oral cancer drug, compared to those receiving a placebo. The study showed improved median survival and response rates, offering new hope for patients with this challenging disease.
A new study finds that people with Alzheimer's disease experience accelerated cognitive decline after being placed in a nursing home. However, those with prior adult day care experience fare better during the transition. The research suggests that experience in day care programs may help prepare individuals for institutional living.
Researchers at Rush University Medical Center are part of a worldwide effort to create an easy-to-use, affordable test to measure immune systems in HIV-positive patients. The CD4 Initiative aims to provide rapid, robust, and affordable diagnostic tools to healthcare workers in developing countries.
A Phase I study at Rush University Medical Center found that adult stem cell therapy significantly improved heart, lung, and global function in heart attack patients. Patients receiving the therapy experienced a lower number of adverse events and were 75% less likely to experience arrhythmic events compared to those receiving a placebo.
A recent study published in Archives of General Psychiatry found that individuals experiencing loneliness are at a significantly increased risk of developing Alzheimer's disease. The research, conducted over four years, analyzed data from 823 older adults and revealed that loneliness was associated with a 51% increased risk of developi...
Researchers at Rush University Medical Center found significant differences between antihypertensive drugs and their risk of new-onset diabetes. ACE-inhibitors and ARBs prevent diabetes, while diuretics and beta-blockers increase the risk. The study analyzed 22 long-term randomized clinical trials and included 143,153 patients.
The Chicago Parent Program, a successful parenting skills program, aims to reduce child misbehavior by equipping parents with preventive strategies. A new study will explore ways to increase parent participation and provide insights into the cost-effectiveness of the program.
Researchers found that memory problems in older adults are associated with Alzheimer's disease pathology in the brain. The study used memory complaint scores to identify individuals with brain changes linked to Alzheimer's disease, suggesting that memory complaints may serve as an early warning system.
Medicaid patients are less likely to receive recommended cardiac care, including short-term medications and invasive procedures. They also have higher in-hospital mortality rates and are less likely to receive recommended discharge care. The study suggests that system problems and biases may contribute to these disparities.
A study led by Rush University Medical Center found the Perspecta Spatial 3D system enhances radiation treatment planning by providing a better understanding of tumor location and size. The device generates true 3D imagery, allowing for more efficient and natural visualization of anatomical and dose data.
A study of 3,718 residents found that eating at least 2.8 servings of vegetables per day slowed cognitive change by 40% compared to those who consumed less than one serving per day.
Researchers found PPM abuse varies greatly across US states, differing from traditional illicit drug trends. States with large metropolitan areas often have lower abuse rates despite perceptions of city dwellers being more prone to drug use.
A Phase 1 study of CERE-120, a gene therapy product, demonstrated significant symptom reduction in patients with advanced Parkinson's disease, reducing UPDRS motor 'off' scores by approximately 40%. The treatment also showed promising results in improving 'on' time and reducing 'off' time.
A study found that high-fat diets rich in copper are linked to faster cognitive decline in older adults. Those consuming the most saturated and trans fats, along with higher copper levels, showed accelerated mental decline.
A study published in the Journal of Gerontology found that higher blood pressure is associated with a decline in walking ability in older persons. The research, led by Dr. Raj Shah, suggests that controlling blood pressure may help prevent gait difficulties in older adults.
Researchers used gene therapy to deliver glial-derived neurotrophic factor (GDNF) directly to the brain cells of mice with Huntington's disease, protecting neurons from degeneration. The study showed improved behavioral function and reduced symptoms in mice treated with GDNF, suggesting a new approach to forestall disease progression.
Researchers found that melatonin improved sleep efficiency during non-natural sleep periods, but not during natural sleep cycles. The study used 36 healthy young adults who took melatonin supplements to aid sleep at irregular times.
Researchers found that larger social networks are associated with reduced cognitive impairment in people with Alzheimer's disease pathology. The study suggests that healthy interactions with friends and family can have a positive impact on disease prevention.
Researchers are conducting a trial to use mesenchymal stem cells (MSCs) to repair damaged heart muscle after a heart attack. The MSCs can be grown in large numbers and stored for years, allowing a single donation to treat thousands of patients.
A recent study found that tetrabenazine, a medication currently available in Europe and Canada, showed significant improvement in reducing chorea, a hallmark symptom of Huntington's disease. The study involved 84 patients and was led by Dr. Kathleen M. Shannon.
A study found nearly 78% of test subjects had neurofibrillary tangles in the substantia nigra, linked to increased gait impairment. The relationship was independent of dementia status and only affected gait.
A study at Rush University Medical Center found that 96% of patients underwent minimally invasive knee replacement surgery could be discharged the same day without any complications. The key to this success was a comprehensive team approach, including pre-surgical education, optimized care pathways, and post-operative rehabilitation.
Pediatricians report encountering vaccine refusal in 85% of cases, with the most common reasons being safety concerns, philosophical reasons, and religious beliefs. Some physicians may choose to dismiss families from their practice if parental vaccine refusal is not addressed.
A new non-surgical approach combining stent-assisted coil embolization has shown success in treating wide-necked brain aneurysms, improving patient outcomes with minimal recovery time. The procedure has been found to have a high rate of complete closure without compromising the parent vessel.
A new study found that not enough exercise in women can lead to serious heart problems and death, with those who cannot achieve 85% of their age-predicted fitness level being twice as likely to die. The researchers developed a chart for women to interpret their exercise capacity based on normative values for their age.
Researchers found that women have more global AD pathology due to neurofibrillary tangles and experience clinical symptoms of AD nearly 20 times more often than men. This suggests that Alzheimer's disease is stronger in women, potentially linked to estrogen deficiency or other protective factors.
A study of 2,019 middle-aged women found that college education was protective against obesity for white women, but not African American women. The disparity in weight gain persists despite higher educational attainment.
The Rush University Medical Center has been designated as the first HDSA Center of Excellence in Illinois, providing a range of medical and social services to Huntington's disease patients. The center will also explore the creation of a regional network of care providers, including end-of-life care.
A study of 180 Catholic nuns and priests found that nearly half with mild cognitive impairment met pathologic criteria for Alzheimer's disease. Meanwhile, about a quarter had cerebral infarcts, indicating a possible 'reserve' capacity in the brain that prevents cognitive decline despite pathology.
A phase II clinical research study uses VEGF-2 gene therapy to stimulate growth of new blood vessels, relieving angina symptoms. The study aims to improve quality of life for patients with refractory chest pain.
A study of 563 Chicago-area women found that postmenopausal status is associated with a significant decline in pinch strength and marginally significant decline in grip strength. Physical activity may help stave off these declines, possibly due to its influence on metabolic and neurologic mechanisms.
Researchers at Rush University Medical Center are exploring a new gene transfer technique that uses CERE-110 to deliver nerve growth factor to specific areas of the brain affected by Alzheimer's disease. The goal is to prevent cell death and reverse cell atrophy, which may have a widespread effect on the entire brain.