Researchers found that ground cinnamon can reverse biomechanical changes in mice with Parkinson's disease by protecting neurons and normalizing neurotransmitter levels. Cinnamon is metabolized into sodium benzoate, an FDA-approved drug used to treat hepatic metabolic defects.
A recent study suggests that chronic disruption of circadian rhythms may contribute to inflammatory bowel disease and other harmful conditions. Consuming a high-fat, high-sugar diet can worsen the effects of circadian rhythm disruption on intestinal flora.
The NeuroPace RNS System uses responsive stimulation to suppress seizures before they begin, reducing seizure frequency by up to 50%. The device is surgically placed and coupled with a unique electrode placement planning system that facilitates precise targeting of the seizure focus.
African-Americans may be at a higher risk for developing Alzheimer's disease due to biologic and cultural factors. Researchers emphasize the need for increased participation of African-American participants in research studies to better understand the disease.
The prevalence of antibiotic-resistant bacteria, particularly ESBL-producing bacteria, is increasing in US children, raising concerns about dwindling treatment options. These infections can lead to longer hospital stays, higher healthcare costs, and increased mortality.
A newly-developed dietary fiber with a slow release mechanism may alleviate IBS symptoms and improve gut health, targeting the distal colon where colon cancer and other diseases occur.
Neurological researchers have discovered a significant link between abdominal fat and memory loss, finding that the same protein controlling fat metabolism in the liver also resides in the memory center of the brain. This study suggests that people with high levels of abdominal fat may be at risk for memory-related problems later in life.
A new study by Rush University Medical Center found that mobility shoes significantly reduced knee loading in osteoarthritis patients, even after the shoes were no longer worn. The study suggests that footwear choice may be an important consideration in managing knee osteoarthritis.
A new study by Rush University Medical Center researchers found that a sudden decrease in testosterone levels may cause Parkinson's-like symptoms in male mice. Testosterone supplementation reversed the pathology in the mice. The study suggests that preserving testosterone levels may be important to prevent Parkinson's disease.
A recent study by Rush researchers found that older adults subjected to elder abuse face a greater risk of hospitalization than their non-abused peers. The study, which analyzed data from over 6,600 community-dwelling older adults, showed that reported elder abuse was independently associated with increased rates of hospitalization.
Researchers at Rush University Medical Center found that buphenyl increases beneficial proteins in the brain, protects neurons, and improves memory and learning in mice with AD-like pathology. The study offers a promising avenue for treating Alzheimer's disease.
The study found that increased breast milk intake by 10 milliliters per kilogram per day reduced the odds of sepsis by almost 20%. Breast milk also lowered NICU costs by $20,000 to $32,000 per day. This research is significant for its economic impact on risk of infection and related hospital care costs.
Researchers at Rush University Medical Center identified a chemokine known as monocyte chemoattractant protein-1 (MCP)-1 and its receptor, chemokine receptor 2 (CCR2), as central to the development of osteoarthritis pain. This finding could lead to new treatments for this debilitating condition.
People who experienced hunger as children had slower cognitive decline than those who never went hungry, with African American participants showing a significant protective effect. The study suggests calorie restriction or selective survival effects may be responsible for this finding.
A retrospective study found that regular mammography screening can help eliminate the disparity in breast cancer mortality between black and white women. Women screened regularly were more likely to have hormone receptor-positive breast cancers, suggesting early detection can blunt negative prognostic biological characteristics.
Researchers found a medication to be effective in addressing social withdrawal and challenging behaviors in fragile X syndrome patients. The study suggests potential implications for individuals with autism spectrum disorder, who also experience significant social deficits.
A new study published in Neurology suggests that emotional neglect in childhood is associated with a higher risk of stroke in adulthood. The study found that individuals who experienced moderately high levels of childhood emotional neglect were nearly three times more likely to develop a stroke than those with lower levels.
Experts say that younger men with erectile dysfunction are twice as likely to develop cardiovascular disease. A thorough non-invasive cardiovascular disease evaluation is recommended for all men diagnosed with organic ED due to low testosterone levels and other risk factors.
Researchers at Rush University Medical Center have discovered alpha-synuclein protein in the intestinal wall of patients with early Parkinson's disease, but not healthy subjects. This finding may lead to pre-motor diagnosis and accurate biomarkers for tracking its progress.
A new study found that people who reported greater purpose in life exhibited better cognition than those with less purpose, even as plaques and tangles accumulated. This suggests that engaging in meaningful activities promotes cognitive health in old age.
A new study by Rush University Medical Center found that daily physical activity is associated with a reduced risk of Alzheimer's disease and cognitive decline. The study, which tracked the activities of 716 older individuals over 3.5 years, showed that those in the bottom 10% of daily physical activity were more than twice as likely t...
A new study by Rush University Medical Center found that lung cancer screening with low-dose spiral CT scans can detect early-stage disease and reduce cancer-related deaths. The study estimates that commercial insurers should consider providing this benefit to high-risk individuals, which could lead to significant cost savings.
Researchers found that memory decline speeds up in the last two-and-a-half years of life compared to previous stages, with mentally active individuals showing better cognitive health. Activities such as reading and playing board games were linked to preserved memory during late life.
The survey found that 81% of employers target lifestyle habits such as physical activity, tobacco use, and weight management. Employers that tracked screening results reported measurable improved outcomes in blood pressure, cholesterol levels, and body mass index.
A new study published in Neurology suggests that hospitalization in older adults is associated with a faster rate of cognitive decline. The study, which analyzed data from 1,870 participants over 12 years, found that overall cognitive function declined more than twice as fast after a first hospital stay.
A large prospective study indicates that chronic air pollution may accelerate cognitive decline in older adults, particularly in women. Higher levels of particulate matter exposure were associated with significantly faster cognitive decline over a four-year period.
A new treatment for hemophilia A has shown significant reductions in bleeding events and infusion frequency, particularly in children and adolescents. The study suggests that prophylaxis is the optimal treatment for patients with severe hemophilia, improving quality of life.
A team of scientists led by Thomas E. DeCoursey discovered a gene in dinoflagellates that controls voltage-gated proton channels, found also in humans and other species, with bioluminescence and potential applications in controlling deadly red tides
Researchers at Rush University Medical Center found a link between low vitamin B12 levels and reduced brain volumes in older adults. Cognitive tests revealed lower scores among participants with high vitamin B12 deficiency markers.
Patients with narrowed brain arteries who received intensive medical treatment had fewer strokes and deaths than those who received a brain stent. Medical management was found to be the most effective treatment option for preventing stroke prevention.
A study found that microscopic lesions in 30% of older brains without diagnosed disease could cause common signs of aging, such as slower walking and balance issues. The researchers suggest that undiagnosed small vessel disease needs additional tools for detection.
Rush researchers identified a molecule, an antibody, in the bloodstream of infertile women that could be used to screen for high-risk individuals or those with early-stage ovarian cancer. Significant levels of mesothelin antibodies were found in women with premature ovarian failure and ovulatory dysfunction.
Researchers propose a new counseling model that views obesity as a result of neurobehavioral processes, rather than personal choice or willpower. The approach highlights three key factors: food reward, inhibitory control, and time discounting, and recommends strategies to help patients overcome these challenges.
A new clinical trial is underway to examine the efficacy of STX209, a medication that has shown promise in improving social behaviors in people with Fragile X syndrome. The trial, which includes adults and children, aims to assess the safety and tolerability of the drug in treating social withdrawal symptoms.
A Rush University Medical Center scientist is studying cinnamon's effects on multiple sclerosis, a disease that attacks the central nervous system. The research aims to understand how cinnamon's anti-inflammatory property may counteract the disease process in mice.
A clinical trial published in the New England Journal of Medicine reveals that a vaccine combined with Interleukin-2 improves response rate and progression-free survival for patients with advanced melanoma. The vaccine stimulates the immune system to recognize and attack tumor cells, resulting in increased survival rates.
Research at Rush University Medical Center found that frequent social activity may help prevent or delay cognitive decline in old age. Socially active participants showed reduced rates of cognitive decline compared to less active individuals.
Researchers found that thinner brain areas associated with Alzheimer's can predict dementia and disease development. The study analyzed MR images from two groups, revealing a threefold increased risk of Alzheimer's among those with the thinnest cortical areas.
Researchers have identified four new genes linked to Alzheimer's disease, adding to the existing understanding of its causes. The findings, published in Nature Genetics, provide key information for developing treatments and preventive measures.
The Chicago Antimicrobial Resistance and Infection Prevention Epicenter (CARPE) program aims to reduce healthcare-associated infections, antibiotic resistance and other adverse events. Researchers will use data from electronic health records to develop practice guidelines and policies to control antibiotic use.
Researchers at Rush University Medical Center are testing a gene therapy product called CERE-120 to evaluate its effectiveness in reducing symptoms of Parkinson's disease. The treatment involves delivering the human gene for neuturin directly to degenerating dopamine neurons in the brain.
Researchers at Rush University Medical Center found that a three-minute diluted betadine lavage and skin painting with a 10% betadine solution nearly eliminated early deep post-operative infections in total knee and hip joint replacement surgeries. The rate of infection was reduced from 0.97% to 0.15%.
Research at Rush University Medical Center found that higher levels of social activity decrease the risk of developing disability in old age. Participants who reported a high level of social activity were twice as likely to remain free of daily living disabilities compared to those with low social activity.
A new study published in Science Translational Medicine found that a drug called AFQ056, developed by Novartis Pharmaceuticals, showed promising results in treating Fragile X syndrome. The treatment improved symptoms in some patients with a specific DNA marker, and was well-tolerated without safety problems.
A new study reveals how HIV evades the body's natural defense system by hiding a critical protein from natural killer cells. The research opens up a promising new target for HIV drug therapies.
A study by Rush University Medical Center researchers found structural brain changes in individuals at risk for Alzheimer's disease. Those who progressed to the disease showed thinning of cortical areas receiving input from a specific brain region.
Researchers at Rush University Medical Center are exploring the mechanisms of stroke recurrence in patients with intracranial atherosclerotic disease. The MoSIS trial aims to identify causes of strokes in these patients, which is estimated to occur in 25% within two years of initial stroke.
A study published in Brain Stimulation found that transcranial magnetic stimulation (TMS) is an effective, long-term treatment for major depression. The therapy was shown to be durable in the majority of patients and prevented relapse when reintroduced as an adjunct to medication.
Researchers at Rush University Medical Center have identified neutral sphingomyelinase as a key player in the progression of Alzheimer's disease. By inhibiting this protein, they were able to prevent activated brain cells and beta-amyloid from killing neurons.
A study published in Neurology found that mild memory changes are caused by brain lesions associated with Alzheimer's and other dementias, contradicting the long-held notion that age is a primary factor. The study involved over 350 participants and showed a rapid decline in cognitive function in the last four to five years of life.