Researchers found that participants who closely adhered to a DASH-style diet were less likely to develop depression than those who did not. The study, funded by the National Institutes of Aging, evaluated 964 participants and showed an association between a healthier diet and lower rates of depression.
A study published in Movement Disorders found that lower levels of alpha-synuclein protein in cerebrospinal fluid are associated with postural instability and gait difficulty in Parkinson's disease patients. The study also suggests that lower beta-amyloid levels may be related to memory problems in Parkinson's patients.
Higher levels of lifestyle physical activity are associated with increased gray matter volume in the brain of older adults. The study found a significant correlation between daily activities such as household chores, walking dogs, and gardening and improved cognitive function.
A quality improvement project found that 80% of patients completed advance directives after discussing their wishes with a hospital-based chaplain. Chaplain-facilitated conversations provided patients with peace of mind and reduced family member guilt, as they documented their wishes in a shared document.
Researchers at Rush University Medical Center developed the MIND diet to promote brain health, which has been associated with reduced Alzheimer's risk and slower cognitive decline. Study results show that stroke survivors who adhered to the diet had substantially slower rate of cognitive decline compared to those who didn't.
A research team at Rush University Medical Center is working on a simple blood test to detect non-small cell lung cancer with 90% accuracy. The goal is to identify biomarkers that can detect the disease earlier and reduce late-stage diagnoses, improving treatment outcomes.
A study published in Neurology suggests that consuming daily leafy green vegetables can help preserve memory and thinking skills as people age. The research found that those who ate more leafy greens showed a slower rate of decline on cognitive tests, equivalent to being 11 years younger in age.
A randomized clinical trial found that high-intensity exercise three times a week slows worsening of Parkinson's symptoms, while moderate intensity workouts have no effect. The study suggests that high-intensity exercise may be an effective treatment for delaying disease progression.
Researchers found that high levels of suPAR are a reliable predictor of kidney damage in children, similar to adults. The protein is associated with increased risk of kidney loss and progression in children with mild to moderate kidney disease.
A new clinical investigation is testing whether genetic screening can identify patients with a specific mutation who are the best candidates for deep brain stimulation surgery. The study aims to determine how this genetic information can inform surgical decisions and potentially improve outcomes for Parkinson's disease patients.
A study of 930 older adults found that non-elective hospitalizations accelerated cognitive decline by 60%, while elective hospitalizations had no association. Researchers highlight the need for attention on hospitalization as a risk factor for dementia and cognitive decline in older adults.
Researchers found that high suPAR protein levels combine with common genetic mutation to trigger disease onset and define rate of progression. The study used large cohorts of black patients with genetic risk factors for chronic kidney disease and found that plasma suPAR levels predict renal function decline.
Researchers discovered how dying cells alert neighbors to replace them, a process called compensatory proliferation signaling (CPS). Specialized vesicles containing the CrkI protein travel to neighboring cells and cause them to create new cells.
A new combination immunotherapy has shown promise in treating advanced kidney cancer, with the potential to identify biomarkers for many cancers. The study's principal investigator, Dr. Timothy Kuzel, hopes that this treatment will help more patients benefit from immunotherapy.
Researchers discovered two genes, UNC5C and ENC1, associated with aging individuals' better memory and brain function despite accumulated brain pathologies. The study used genetic analysis of 979 organ donors' brain tissue to identify these genes and provide potential new targets for developing medications to enhance brain resilience.
Researchers developed a new vending machine system with a 'delay' bar and LED screen to display delay times for unhealthy snacks. The DISC system led to a 2-5% increase in healthy snack purchases without harming total sales volume or revenue, offering a viable option for vending machine owners.
A new gene variant has been identified in the PTPRD gene that is associated with the accumulation of neurofibrillary tangles (NFTs) in the brain. The study found that this variant affects more than one mechanism of tangle accumulation and may be a key target for developing therapies targeting Tau pathology.
Researchers have identified a new compound that binds to CD11b and enhances its ability to suppress TLR signaling, reducing inflammation in lupus patients. The study found that the compound can override genetic defects associated with ITGAM mutations, offering a personalized approach to treating lupus.
A study found that sleep-tracking devices can be misleading, leading to increased anxiety and poor sleep habits. While these devices may have benefits when used correctly, they can also hinder efforts by therapists to assist patients with sleep disorders.
A new study called Latino Core aims to learn about the aging process and risk factors for Alzheimer's disease in older Latino adults. The study will enroll over 300 participants and include yearly visits, memory exams, and brain donation to understand the pathophysiology of dementia in this population.
A randomized, Phase III study will enroll 600 people with suboptimal diets to evaluate the effects of a specific diet on cognitive abilities and brain health. The MIND diet, which includes foods like fish, berries, nuts, and leafy greens, aims to improve brain health by developing new dietary guidelines.
A study published in Nature Medicine identifies bone marrow-derived immature myeloid cells as the source of suPAR, a reliable marker for chronic kidney disease. Elevated suPAR levels have been linked to future chronic kidney disease, potentially enabling early intervention and prevention of recurrence after transplant.
Interventional radiologists at Rush University Medical Center have developed methods to remove filters that previously couldn't be removed, achieving a 100% retrieval rate. The team uses specialized tools and medical expertise to perform minimally invasive procedures.
Research reveals that African American and Latino children have significantly higher rates of corn, shellfish, and fish allergies compared to white children. The study found that wheat allergy is also more common among African American children, potentially contributing to higher rates of anaphylaxis and emergency room visits.
Researchers have developed a new cancer treatment called photoimmunotherapy that combines the immune system with laser energy to target and destroy cancer cells. This innovative technique delivers precise, lethal payloads with minimal collateral damage.
Despite extensive research supporting mother's own milk as most effective option for low birthweight infants, numerous barriers persist in NICUs. Common issues include ineffective breast pumps, inadequate freezer space, and lack of investment in evidence-based practices to optimize milk volume.
Research conducted by Rush University Medical Center found that patients with hypothyroidism who have normal TSH levels are more likely to take antidepressants, be less physically active, and exhibit lower energy levels. These findings indicate that persistent symptoms may not be solely in the patient's head.
A study by Rush University Medical Center found discrepancies in hospital rankings due to faulty data, which can skew safety scores down. The authors suggest that rating systems try to account for severity of illness but often rely on flawed metrics.
A study by Rush researchers found that TDP-43, a previously recognized pathologic protein, is more likely to result in diagnosed Alzheimer's dementia when combined with plaques and tangles. Mixed pathologies increase the risk of developing Alzheimer's dementia above and beyond just having these brain abnormalities.
Researchers from Rush University Medical Center found that diseased blood vessels in the brain may contribute more significantly to Alzheimer's disease dementia than previously believed. The study analyzed medical and pathologic data on 1,143 older individuals and found an association between worsening brain vessel diseases and higher ...
A new study published in the New England Journal of Medicine found that patients with severe hemophilia A who received human plasma-based treatments developed inhibitors at a lower rate than those who received recombinant Factor VIII. This could lead to more effective treatment options for families affected by this rare genetic condition.
A study published in Neurology found that eating seafood at least once a week can help mitigate age-related cognitive decline. Participants who consumed more seafood showed slower rates of decline in semantic memory and perceptual speed, while those with the APOE-ε4 gene showed an even stronger protective association.
Researchers at Rush University Medical Center are conducting a five-year randomized trial to test the MIND diet's effects on cognitive decline and Alzheimer's disease incidence. The study will enroll 600 individuals aged 65+ and evaluate the diet's impact on brain structure, cognition, and health outcomes.
Researchers at Rush University Medical Center found that moderate seafood consumption was associated with less Alzheimer's disease pathology, including lower amyloid plaques and tangles. Seafood intake was only linked to reduced harm when individuals had a specific genetic profile, highlighting the need for personalized nutrition advice.
A recent study at Rush University Medical Center found acupuncture to be a safe and effective adjunctive integrative medicine treatment for chronic pain in pediatric patients. The study included 55 children aged 7-20 who experienced chronic pain conditions, with significant reductions in pain levels and related health issues.
A study in New England Journal of Medicine found that suPAR, a circulating protein, can reliably predict chronic kidney disease up to five years before symptoms appear. High suPAR levels are associated with an increased risk of developing the disease, which affects over 15% of people in the US.
Aging-related changes in physical condition and life circumstances can lead to financial vulnerabilities, which may result in substantial loss of resources. The term age-associated financial vulnerability (AAFV) describes a pattern of behavior placing older adults at risk for considerable loss of resources.
A nationwide study found a significant increase in CRE infections among US children aged 1-5, with rates rising from 0% to 4.5% between 1999 and 2012. The greatest increase was seen in intensive care units, where isolates of CRE in the bloodstream increased from zero to 3.2% during the study period.
A Phase 1 clinical trial is assessing the safety and activity of a special cell therapy for individuals with complete cervical spinal cord injuries. The therapy uses oligodendrocyte progenitor cells derived from human embryonic stem cells to potentially improve motor or sensory function.
A recent study found that older adults who followed the MIND diet more rigorously showed equivalent cognitive abilities to those 7.5 years younger, suggesting a potential delay of dementia's onset. The MIND diet emphasizes brain-healthy food groups and limits unhealthy foods, with berries being a key component.
The Chicago Ebola Resource Network (CERN) shares expertise, resources, and risk to anticipate and respond to Black Swan events. Collaborative efforts among academic medical centers and public health leaders resulted in efficient programs with reduced disruption to routine patient care.
The project aims to equip hospital chaplains with research skills, enabling them to guide, evaluate and advocate for spiritual care. This will advance outcome-oriented chaplaincy care and align with the growing body of evidence connecting religion and spirituality with better patient outcomes.
A study found that removing clots in severe strokes, combined with medication, improves blood flow and may lead to better long-term outcomes. The treatment shows promise as a game-changer for certain types of stroke patients.
A new diet, MIND, shows reduced risk of Alzheimer's by 35-53% in participants who adhered moderately well, with benefits from brain-healthy food groups and limits on unhealthy foods. Long-term consistent adherence is crucial for optimal protection.
The Roadmap Epigenomics Project has released new annotations of the human genome, which may hold the key to understanding and combating diseases. By mapping epigenetic signatures associated with complex traits, researchers aim to better understand how genes change and develop effective treatments for Alzheimer's disease.
A new standard of care for soft tissue sarcomas has been established through a study that shows image-guided radiotherapy can reduce long-term side effects while maintaining survival rates. The treatment delivers smaller radiation doses to tumors, minimizing exposure to surrounding healthy tissue.
A study published in the Journal of Clinical Investigation found that a genetic polymorphism may be responsible for why standard treatments for hypothyroidism fail some patients. The researchers suggest that personalized medicine could lead to effective treatment for all patients, and identify potential targets for new therapies.
Researchers are developing new tests to track changes in cognitive functioning of people with intellectual disabilities, including those with Fragile X and Down syndromes. The tests will assess processing speed, memory, attention, and language skills.
A new blood test has been identified as a potential predictor for focal segmental glomerulosclerosis (FSGS), a devastating form of kidney disease. The test, called FAST, uses high-density protein tests to detect antibodies against specific antigens that are significantly increased in patients at risk for FSGS.
A new study by Rush University Medical Center researchers found that depression is independently associated with an increased risk of developing dementia. The study suggests that targeting and treating depression could help prevent or delay cognitive decline in older adults.