Researchers at the University at Buffalo found that consuming a high-fat meal causes an increase in inflammatory components in the blood. However, taking antioxidant vitamins E and C before consumption can nullify this effect.
A new study by University at Buffalo researchers found that insulin sensitizer rosiglitazone (Avandia) has a significant anti-inflammatory effect in Type 2 diabetes patients. The drug decreased levels of oxygen free radicals and inflammatory markers, reducing the risk of heart disease.
Researchers found that volcanic eruptions can completely reverse the influence of sunspots on global climate, contradicting previous assumptions about their relationship. By studying ice cores, they discovered that explosive volcanic activity coincides with correlation reversals between sunspot activity and climate.
A new study by UB researchers provides the first scientific proof that handwriting is unique to each individual, setting a significant standard for handwriting analysis in forensic applications. The team's software system can distinguish with 96% confidence whether two documents were written by the same person or different people.
A Canadian debate over for-profit hospitals has been informed by a study showing these facilities have significantly higher mortality rates compared to non-profit hospitals. The analysis of 38 million patients found that the profit motive leads to reduced staffing and limited care, resulting in increased mortality.
A study found that drinking white wine recently and over a lifetime was associated with better lung function. The researchers think the antioxidants in wine account for this positive effect. Wine consumption was linked to higher levels of protective antioxidants in the blood, which may help protect lung health.
A new study funded by a $350,000 grant aims to examine how alcohol impairs women's ability to recognize and respond to risk of sexual aggression. The research will provide information on resistance strategies to help women engage in safer dating situations.
Researchers at the University at Buffalo's Buffalo Neuroimaging Analysis Center are providing new insights into multiple sclerosis using advanced MRI brain imaging methods. They have found that the brain's gray matter, where higher functioning is centered, is involved in MS and has identified a potential target for treatment.
Researchers at the University at Buffalo have developed a new semiconducting material that exhibits key properties for spintronic devices, including ferromagnetism and hysteresis. This breakthrough could lead to faster processing speeds, non-volatility, and potentially quantum computing capabilities.
A UB study finds that early nutritional modification programs metabolism, predisposing to obesity. High carbohydrate diets led to changes in islet cells, overproduction of insulin, and alterations in the insulin secretory pathway.
A study by Timothy Sullivan found that homeless urban Guatemalan street children have a similar average body mass index (BMI) to American children, suggesting better health and survival rates despite harsh conditions. The research challenges previous assumptions about the negative impact of homelessness on child health.
Scientists at University at Buffalo used chitinase to identify the extracellular transport signal of cholera toxin, a crucial step in understanding how bacteria cause disease. The researchers found that only a portion of a specific region of the protein was essential for its secretion.
A study suggests that insulin can suppress a pro-inflammatory transcription factor that promotes clot formation in blood vessels. Insulin infusion reduced levels of tissue factor and plasminogen activator inhibitor-1, key players in the development of human and mouse atherosclerosis.
A team of UB researchers has discovered a novel peptide in human saliva with potent antimicrobial activity against various types of bacteria and fungi, including drug-resistant strains. The peptide, labeled MUC7 20-mer, shows activity at very low concentrations and little toxicity to mammalian cells.
A study of German subjects found periodontal disease bacteria in carotid artery samples, supporting the 'infectious burden' hypothesis that oral infection plays a role in atherogenesis. The study also identified multiple types of bacteria, suggesting a complex relationship between gum disease and cardiovascular disease.
Researchers from the University at Buffalo School of Dental Medicine found no relationship between long-term exposure to dental aerosols and respiratory illness among dental students. The study, which analyzed data from over 800 students, suggests that breathing in mists spun off by drills may not cause respiratory problems.
Research found that people who habitually sleep more than 8 hours a night and those who need daytime naps have a 50% increased risk of dying, with nearly three times the risk from stroke. The study suggests an underlying sleep disorder may be to blame.
A UB team has demonstrated a breakthrough in three-photon pumped frequency upconversion, producing fluorescent emissions with higher energy than the laser's pumping photon. This process enables efficient light production for applications such as optical imaging, bioimaging, diagnostics and photodynamic therapy of deep tissue tumors.
University at Buffalo researchers have developed reusable chemical sensors that can detect hundreds of chemicals in an area smaller than a dime. The new technology uses pin-printing to create xerogel-based sensors, which are rigid materials with intricate networks of nanoscopic pores.
Researchers developed a detailed hazard map for Pico de Orizaba, Mexico's highest mountain, using advanced technologies and computer simulations. The map reveals three levels of hazard based on probability, enabling local authorities to prepare for various events such as landslides, mudflows, and eruptions.
Researchers at the University at Buffalo have performed simulations that mimic hydrocarbon combustion, demonstrating a defining feature of combustion and gaining insights into the two-way interaction between chemistry and turbulence. The work aims to develop more realistic models of fluid mechanics and chemistry involved in combustion.
A study of 2,600 Americans found that between 1-2% have a compulsive gambling problem, with rates higher among minorities and lower-income individuals. Problem drinkers are 23 times more likely to also have a gambling issue.
UB researchers found that Ritalin can cause long-lasting changes in brain cell structure and function, similar to other stimulant drugs. The study suggests that Ritalin's effects may outlast the initial dose, leading to concerns about its long-term impact on the brain.
Theoretical physicists at UB have developed a system that can reduce the amplitude of physical impact by 95-98 percent, and harness dissipated energy into usable thermal energy. The research has potential applications in bridge, ship, and building protection, as well as harnessing energy from natural phenomena.
Researchers investigating cumulative effect of maternal cocaine use on infants' mental development, examining interactions with environment, family violence, and substance co-use. The study aims to understand how children develop self-regulation and control impulses.
Researchers at the University of Buffalo have discovered that cells 'wiggle' at high speeds when exposed to voltage changes, without relying on special proteins or lipids. This fundamental property of cells opens up new avenues for studying cell motility and its potential applications in medicine.
A new study by University at Buffalo researchers found that insulin can reduce pro-inflammatory components in the bloodstream while increasing anti-inflammatory components. The results suggest that insulin may have anti-atherosclerotic effects and potentially reduce the risk of heart attack, contrary to previous assumptions.
A UB study found that Mexican Americans who primarily speak Spanish and are less 'Americanized' are significantly less active during leisure time. This disparity is associated with acculturation, which affects physical activity habits.
Research finds that fathers' alcohol abuse and depression are associated with emotional and behavioral problems in children, including anxiety and depression. The study also highlights the importance of considering maternal depression when evaluating the effects of paternal alcohol abuse.
A study by UB researchers found that more than half of survivors diagnosed with uncontrolled high blood pressure still had hypertension, and 46% of those with dangerously high cholesterol continued to have high levels. This highlights the need for improved secondary prevention strategies in the US population.
A study published in Ethnicity and Disease found that cocaine use and hypertension are major risk factors for brain hemorrhage in young African Americans. The researchers also discovered that the incidence of intracerebral hemorrhage is nearly 50 times higher in African Americans than in white patients.
Researchers found a significant association between chronic respiratory disease and periodontal disease in the Third National Health and Nutrition Examination Survey. Poor oral health worsens respiratory function and may increase risk of serious lower-respiratory-tract infections.
Researchers at the University at Buffalo have developed a computer program that can analyze handwriting and determine authorship with high accuracy. The software uses scientific criteria to quantify performance and increase confidence in identifying writers, which is essential for admitting handwriting evidence in U.S. courts.
A specific protein isolated from Chilean tarantula venom shows promise as a basis for new drugs to prevent atrial fibrillation, a major cause of death following a heart attack. The research demonstrates the physiological function of mechanosensitive ion channels in the heart for the first time.
A new study from the University at Buffalo reveals that obese individuals carry a massive oxidative load that increases their risk of heart disease. Severe calorie restriction decreases free radical production by over 50%, reducing the risk of developing heart disease without medication.
The Hauptman-Woodward Medical Research Institute and University at Buffalo have received $3.13 million to develop new methods for determining protein structure, crucial for designing new drugs. Researchers will use X-ray crystallography and NMR spectroscopy to determine protein structures.
Researchers found a cellular signaling system that responds to THC and anandamide regulates sperm functions required for fertilization in humans. Heavy marijuana users may jeopardize fertility by overloading this natural signaling system.
University at Buffalo chemists found that nitric oxide is highly reactive with ethanol, making it a potentially more insidious pollutant. The study's findings provide new insights into how solvation affects chemical reactions and could help scientists better tailor lab experiments.
A new UB study reveals a significant association between breast cancer risk and physical characteristics of insulin resistance, including abdominal fat distribution and higher-than-normal male and female sex hormones. Women with increased waist-to-hip ratio and oily skin are at greater risk of developing breast cancer.
Massive sheets of lava produced by flood basalt eruptions generated intense heat, pushing ash and gas into the upper atmosphere and causing dramatic global-scale climate shifts. These events are now believed to have contributed to mass extinctions, including those that wiped out dinosaurs.
A recent study found that 57% of women who drank in bars reported experiencing verbal or physical aggression. Women should be aware of their own risky behaviors and the bar environment's impact on aggression.
Researchers at the University at Buffalo have found that a combination of fish oil and vitamin E reduces inflammation-inducing cytokines in mice with rheumatoid arthritis. This study suggests that these nutrients may delay symptoms and improve function for patients with this disease.
A University at Buffalo study has found that people with severe gum disease are twice as likely to suffer a stroke due to blocked arteries. Periodontal disease was associated with an increased risk for cerebrovascular events, particularly non-hemorrhagic strokes.
A prospective study of 10,786 Italian women found a 40% lower risk of breast cancer in premenopausal women with the C-2 estrogen metabolism pathway, which produces less active by-products. Lifestyle changes such as physical activity and a low-fat diet high in cruciferous vegetables may shift estrogen metabolism from high-risk to low-risk.
A recent UB study found no association between high-normal iron levels and risk of death due to cardiovascular disease, coronary heart disease or heart attack. However, black men with low levels of excess iron were at three times the risk of death from any cause.
Children born prematurely are 3 to 4 times more likely to be educational underachievers than full-term children. Targeted educational intervention programs can help maximize their academic potential. The study controlled for age, race, maternal education, and foster-care placement.
Researchers found that children with a parent who had a premature heart attack showed structural and functional abnormalities in their arteries as young as 6 years old. These changes included thickened vessel walls and decreased reactivity, which can lead to atherosclerosis and increase the risk of heart disease.
The University at Buffalo is leading a $10 million DARPA project to develop specific ferromagnetic materials for use in spintronics. The goal is to create magnetic semiconductors and prototype devices to exploit electron spin properties, enabling new functions in data processing, storage, and communications.
Researchers at the University at Buffalo found that impaired pulmonary function was associated with increased risk of mortality over a nearly 30-year period. The study showed that individuals with poorer lung function were more than twice as likely to die, highlighting the importance of regular lung function testing
Elaine M. Hull receives a $602,759 Independent Scientist Award to expand her research on hormone and neurotransmitter interactions in the brain. She aims to clarify how gonadal hormones influence neurotransmitter release in the medial preoptic area, essential for male copulation in all vertebrate species.