A study published in The Journal of Clinical Endocrinology and Metabolism found that excess glucose consumption stimulates the generation of free radicals, which can damage cells lining blood vessels. The researchers also observed a decrease in levels of a-tocopherol, a powerful antioxidant.
Insulin reduces expression of molecule promoting inflammation and clogging of arteries, increasing production of vasodilator nitric oxide. The study's findings indicate insulin may have an antiatherosclerotic role, potentially protecting people at risk of CVD.
Anthony Auerbach, a University at Buffalo biophysicist, has been awarded a $2.7 million Jacob Javits Neuroscience Investigator Award to continue his distinguished research on cell communication and synapses. His focus will be on understanding acetylcholine receptors, proteins that facilitate chemical messages across brain synapses.
The University at Buffalo will host a global conference on environmental health, bringing together over 500 researchers and experts from around the world. The conference aims to assess the worldwide disease burden caused by environmental problems and build connections among health centers in Pan America and globally.
A recent UB study found that the 'healthy worker effect' can skew results of health studies involving workers, particularly among female nuclear-weapons workers. The study suggests that this bias must be taken into account to obtain accurate results, emphasizing the need for appropriate comparisons and consideration of unexposed workers.
A University at Buffalo study found that a woman's biology, specifically age at first menstruation and first live birth, are major predictors of resolved fertility in fertile women, not lifestyle habits. Women over 30 at first live birth were three times more likely to take longer than a year to conceive.
A study by Scott Coffey found that cocaine withdrawal symptoms are relatively mild and decrease steadily over time, with improvements in depression, anxiety, and energy levels.
A UB study found that obese children are more likely to have high levels of triglycerides and low levels of protective cholesterol, increasing the risk of heart disease later in life. The research, which analyzed data from over 4,000 children, suggests that monitoring body mass index is crucial for early detection of dyslipidemia.
A new study by the University at Buffalo has found that African Americans and Mexican Americans experience significantly poorer oral health than white Americans. The research, based on national data from 1988-94, shows that nearly half of African American men and one-third of African American women had periodontal disease, compared to ...
A University at Buffalo study found that men with testicular cancer are two-thirds less likely to have fathered a live infant and nine times more likely to have been diagnosed as infertile than healthy controls. The research contradicts earlier findings that showed no relationship between fertility and testicular cancer diagnosis.
A University at Buffalo study shows that exercise training improves muscle function and protects against injury in aging animals. Regular exercise can help prevent frailty in seniors by strengthening muscles and reducing the risk of injury.
Researchers at University at Buffalo develop a system that allows physicians to store information about their touch during an exam using virtual reality. This data can be accessed by other physicians, enhancing clinical palpation and enabling more accurate diagnoses.
Researchers identify a component of Chilean tarantula venom that specifically blocks stretch-activated channels, implicated in various physiological processes. This peptide toxin shows promise in treating conditions such as congestive heart failure, heart attacks, and brain tumors.
A new NIH clinical advisory statement recommends using systolic blood pressure as the primary criterion for diagnosing and treating hypertension in middle-aged and older Americans. This shift aims to improve outcomes by targeting systolic pressure, which is associated with a higher risk of heart disease.
Researchers at UB School of Dental Medicine found a strong link between obesity and gum disease, with overweight individuals showing a 50% increased risk of severe periodontal disease. The study also suggests that bacteria in the mouth may contribute to insulin resistance, increasing the risk of Type 2 diabetes and heart disease.
Researchers found calcified plaque in 7.5% of participants, doubling risk of death from cardiovascular disease compared to those without plaque. This discovery moves towards using panoramic dental radiographs as a screening tool for all cardiovascular disease.
A study found that mothers with alcohol and drug problems tend to be more punitive towards their children, using aggressive disciplinary strategies. This research highlights the need for interventions that address not only individual substance abuse but also family dynamics.
A study by UB neurosurgeons found that cigarette smoking is associated with larger brain aneurysms, which can lead to life-threatening complications. The research, published in the journal Neurosurgery, showed that smokers were more likely to develop large aneurysms than non-smokers.
A University at Buffalo professor is using the case-study approach to revolutionize the teaching of science, resulting in improved student attendance and engagement rates. The grant will establish a national center for case study teaching in science, providing faculty with training and resources.
Researchers at the University at Buffalo have developed a new method to study protein dynamics in transition states, shedding light on the structural changes during activation. This breakthrough could lead to new drug development and insights into conditions like congenital myasthenia syndrome.
A new software game is being launched to address the lack of computer educational activities for girls, particularly those from underrepresented groups. The game, 'The Adventures of Josie True,' features a colorful and multiethnic educational playground that introduces historical characters in their own historically accurate milieu.
The University at Buffalo has received a four-year, $3.8 million grant from the Howard Hughes Medical Institute to develop two new research centers, including a Center for Genomics and Proteomics and a Center for Single-Molecule Biophysics. Five new faculty members will be hired to further develop this area.
UB scientists discovered that soft spots on volcanoes can collapse and trigger devastating mudflows that can travel up to 80 miles. The research highlights the danger of older volcanoes with hydrothermal fluids, which change rock structure and make them more vulnerable to collapse.
A new University at Buffalo study shows that a single dose of Adderall can effectively manage children's behavior and performance throughout an entire school day. The results suggest that 14 out of 16 kids who responded to medication could get by on once-a-day doses of Adderall, skipping the mid-day dose.
Researchers found that chronic alcohol abuse in late adulthood damages Purkinje neurons by reducing message traffic between neurons, but the damage is mostly reversible. The study also suggests a connection between alcohol-induced brain changes and abnormal movements seen in alcoholics, such as unsteady gait and tremors.
Children with juvenile arthritis who participated in an eight-week resistance exercise program showed significant improvements in functional ability, with some experiencing a 200% increase. The program also reduced pain, disability, and medication use.
Millions of defective low-rise buildings in the US lead to high annual losses from windstorms, with recent hurricanes causing $70 billion in damages. A symposium aims to develop a national plan for wind-hazard mitigation and improve building codes.
A University at Buffalo study found that pet dog or cat owners experienced significantly reduced cardiovascular measures during stressful situations compared to non-pet owners. The study showed that having a pet helped to stabilize heart rate and blood pressure in response to mental stress.
Researchers at UB used a fluorescent probe to track the uptake of AN-152, a cancer drug linked to a peptide hormone carrier, by human breast-cancer cells. The study provides evidence that AN-152 directly enters cancer cells, accumulates in the nucleus and associates with chromosomes.
Researchers at the University at Buffalo have found that melatonin speeds up bone formation and increases production of bone matrix proteins, suggesting a potential link to osteoporosis prevention. The study used mouse and rat cells to demonstrate the role of melatonin in promoting bone growth.
A University at Buffalo study found no association between DDE-contaminated sport fish and shorter lactation periods. Women who ate Lake Ontario fish had lower DDE levels in their breast milk, contradicting initial expectations.
Biologists at the University at Buffalo discovered that the presence of a fertile female in the next nest can cause a male to stray, leaving his mate unguarded. The phenomenon is linked to local breeding synchrony, where multiple females lay eggs in the same area.
A new study by University at Buffalo exercise scientists reveals that dehydration can induce bronchospasm before exercise and exacerbate exercise-induced asthma. Researchers found that individuals with asthma are more sensitive to dehydration, leading to reduced respiratory capacity and increased difficulty during physical activity.
A University at Buffalo study found that men recovering from a heart attack who are at the highest risk of a second attack are also the least likely to participate in an exercise program. These men tend to be overweight, have high cholesterol and triglyceride levels, and smoke tobacco.
Researchers in UB's Center of Excellence for Document Analysis and Recognition aim to establish a scientific basis for whether handwriting is unique to each individual. The new tools will enable law-enforcement investigators to analyze handwriting in documents, potentially identifying writers and suspects in criminal cases.
A study by the University at Buffalo found that a very-low-fat diet can suppress the immune system of trained runners, making them more susceptible to infections. The researchers discovered that high-fat diets, on the other hand, enhanced certain components of the immune system and reduced inflammation.
Researchers developed smart concrete that changes electrical resistance in response to strain or stress, allowing for real-time vehicle weighing. The technology has the potential to reduce costs and increase efficiency in highway monitoring.
University at Buffalo engineers develop virtual-factory software called UB VR-Fact! that allows companies to design and simulate large-scale plants virtually. The software uses mathematical algorithms and models to simulate factory layout, production, and identify potential bottlenecks.
A case-control study found that frail elderly who received assistive devices and home adaptations had higher levels of independence at the end of a 18-month study. The treatment group spent significantly less on health care, with average costs $14,173 per person compared to $31,610 in the control group.
A recent UB study found that women eating Lake Ontario fish have higher levels of PCBs and pesticides in their breast milk than non-fish-eaters. The study, conducted on lactating women in the New York State Angler Cohort, shows a decline in toxicant concentrations with increasing number of children and time spent breastfeeding.
Research finds patients treated for Hodgkin's disease as children are nine times more likely to develop a second cancer, with specific types of cancer at higher risk. The study suggests regular screening is necessary to monitor patients' lifetime health.
A new study by researchers at University at Buffalo found that babies born with a congenital growth hormone deficiency are of normal length at birth. The study suggests that growth hormone deficiency does not affect fetal growth, and that persistence of hypoglycemia and jaundice are clues for evaluation of pituitary hormones. Replacing...
A new study published in UB's School of Health Related Professions found that female collegiate soccer players performed longer at a higher intensity on a diet composed of 35% fat than on lower-fat diets. The women showed no increase in weight, body fat, or blood pressure despite consuming a higher amount of fat.
A UB Study found no correlation between male consumption of Lake Ontario fish contaminated with PCBs and pesticides, and delayed conception in women. The study analyzed data from 785 women who had conceived between 1991-93, but did not find a significant link to conception delay, despite concerns about potential reproductive effects.
Researchers found that treating the inner ear with leupeptin before exposure to high-level noise reduced sensory hair cell loss by 60%. However, leupeptin offered no protection against the damaging effects of carboplatin.
A new study has found that Adderall lasts longer than Ritalin in treating ADHD symptoms, and is at least as effective. The trial involved 25 children who took part in an eight-week program and showed significant improvements in social behavior and academic performance with both medications.
A three-year exercise program significantly lowered mortality rates among men who had suffered a heart attack. The study found that increased physical work capacity during the trial period was associated with reduced risk of death at every time period.
Researchers at University at Buffalo discovered that aerosol clusters can amplify chemical reactions, creating carcinogenic by-products from benign reagents. The study may provide a better understanding of how air pollution forms and inform regulation strategies.
Researchers found a direct dose-response relationship between alcohol consumption and gum disease severity. Low antioxidant vitamins like selenium increased the risk of gum disease by 13-fold.
Research from the University at Buffalo School of Dental Medicine found a significant association between periodontal disease and insulin resistance in non-diabetics. The study also showed that individuals with severe gum detachment had a higher risk of developing chronic lung diseases.