A large randomized clinical trial found no association between selenium supplementation and reduced risk of coronary heart disease, stroke, or cardiovascular deaths. The study of 1,004 participants in low-selenium areas showed no difference in endpoints based on baseline selenium levels.
UB researchers have discovered an agent, L-AP4, that activates group III metabotropic glutamate receptors and reverses damage caused by rotenone. The findings could lead to a new treatment for Parkinson's disease.
Researchers at University at Buffalo have determined that the temperature difference between air and water controls the amount of mist at Niagara Falls. The study found that a higher temperature difference results in a thicker and more substantial mist plume, contrary to previous reports linking high-rise hotels to increased mist levels.
A recent study found that only 11% of seniors in Western New York have dental insurance, with financial need being a major barrier to receiving dental care. The study also showed significant disparities in access to dental care between urban and rural areas.
A new method by University at Buffalo engineers calculates the expected cost of managerial neglect in processes with variability, such as supply chains. The model can help managers justify investments for improvement and save up to 50% in costs over three years.
A study of 407 children with early childhood cavities found that only 8.2% were underweight and 16.5% at risk of being overweight in 2000. In contrast, more recent data showed a higher percentage of overweight children, suggesting a connection between poor diet and tooth decay and childhood obesity.
The study found that manipulating a specific signaling pathway in the AT1 receptor altered animal behavior, increasing salt intake without water consumption. This suggests that intracellular events can regulate behavioral states, providing new insights into angiotensin's role in mammalian behaviors.
The study found that antibiotics and synthetic hormones can increase antibiotic resistance and disrupt endocrine functions. Researchers identified key metabolites from commonly prescribed medications and hormone replacement therapy, highlighting the need for optimized wastewater treatment processes to remove these compounds.
Researchers found PDT to be highly effective against drug-resistant bacteria and fungus, including S. mutans and Candida species, with minimal doses of light required to kill nearly all organisms.
A study found that higher-than-normal levels of IL-1-beta in saliva are associated with increased bone loss. Osteonectin levels inversely correlate with bone loss, suggesting this marker may measure periodontal health. The researchers hope to develop a biomarker test for early detection and monitoring.
A study published in Pediatrics found that children who underwent surgery for obstructive sleep-disordered breathing (OSDB) due to enlarged adenoids experienced a significant increase in excess weight, averaging 13% over 12.6 months. This weight gain may be linked to reduced motor activity and poor sleep quality after the surgery.
A study of 2,805 US workers found that 1.8% have consumed alcohol before work and 7.1% drink during the day, with men and younger workers more affected. Most workplace alcohol use is infrequent, but its impact on productivity and safety is significant.
A study of over 79,000 women found that prepregnancy obesity rates increased by 9.2% between 1999 and 2003, linked to higher risks of gestational diabetes, hypertension, preeclampsia, and labor complications. The trend was observed regardless of age, ethnicity, or socioeconomic factors.
A new study by the University at Buffalo, Yale University, and Oregon Health and Science University found that hospital-level care can be provided at home for less money and with fewer clinical complications. The program, called Hospital at Home, resulted in fewer important clinical complications, greater satisfaction, and lower total ...
A University at Buffalo medicinal chemist is working to develop rules for targeting RNA, which could lead to the design of efficient compounds to inhibit specific RNA sequences. This approach has the potential to treat diseases such as cancer and genetic disorders, offering a more targeted alternative to DNA-based treatments.
Researcher Harvey Arbesman links acne and dairy products to the presence of iodine in milk. Studies have shown significant iodine levels in various countries' dairy products. Iodine intake has been linked to acne exacerbation since the 1960s.
Scientists have discovered male water fleas in a lab, revealing that pesticides can induce sex change and affect populations of fish and other organisms. The finding highlights the importance of considering non-target species in environmental monitoring and management.
Researchers found that pravastatin increased endogenous stem cells for cardiac repair, independent of cholesterol-lowering action. High doses improved cardiac function and coronary blood flow in hibernating myocardium, a condition where heart cells reduce their function due to insufficient blood flow.
A recent study published in the journal Hypertension has found a significant association between fatty liver and an increased risk of hypertension and cardiovascular disease. The research suggests that GGT levels are strongly affected by weight and body fat distribution, particularly in overweight participants with central obesity.
Body checking in youth hockey was found to cause relatively few injuries compared to unintentional collisions with boards or players. Despite this, researchers recommend delaying body checking until players are at least 16 years old due to increased injury rates among 13-year-olds.
A new study at the University at Buffalo will explore the impact of cooling on exercise performance in people with multiple sclerosis (MS). The researchers aim to determine which cooling method is most effective and improve physical functioning and cardiovascular health.
A study found that nearly two-thirds of heavy smokers' sperm failed a test measuring fertilizing capacity, with those who smoked more cigarettes per day showing lower fertility rates. The research suggests that heavy smoking overloads the nicotine receptor in human sperm and testes, leading to a decline in fertilizing potential.
Destabilization of microtubules interferes with NMDA receptor action, affecting cognition and emotion. Dysfunction of this regulation may provide a potential mechanism underlying many mental disorders.
The researchers have developed two rapid-solution synthesis methods that can produce robust, water-dispersible quantum dots for bioimaging and organically soluble quantum dots ready for sequestration into a polymer host. The new synthesis methods are scalable and can be used to produce large quantities of quantum dots.
A study published in Addictive Behaviors suggests that shame, not guilt, is related to substance-abuse problems. The research found that individuals prone to shame may use alcohol and other drugs to cope with feelings of self-blame, while those who experience guilt are less likely to develop substance-use problems.
Researchers at the University at Buffalo have identified microtubules as a critical target for treating Parkinson's disease, which is caused by damage to these intracellular highways. The study found that protecting microtubules can prevent the toxic effects of rotenone on dopamine-producing neurons.
According to Campbell, increased voter turnout was a key factor in the 2004 Republican victory. Nearly 60% of eligible voters participated, with competitive states experiencing higher turnout rates. The study also notes that party polarization and incumbent advantage will play significant roles in the 2008 election.
The piecework system, used in large textile factories, eliminates daily wages and overtime, leaving workers with extremely low pay and long working hours. Workers must constantly compete for work, fostering distrust and tension among them.
A study by Robert L. Wagmiller found that highly concentrated joblessness among black men is produced by the multidimensional layering of segregation, creating unique challenges for neighborhoods and employment opportunities. The research highlights the negative impact of residential location on employment futures.
University at Buffalo scientists developed nanoparticles that delivered genes to adult brain stem/progenitor cells in vivo with no observable toxic effect. The technique may allow repairing brain cells damaged by disease, trauma, or stroke. This breakthrough demonstrates the potential for non-viral vectors in gene therapy.
The first year of marriage marks a significant change in relationships, leading to altered dynamics that influence marijuana use. Husbands are more likely to start or resume smoking if their wives do, while wives' influence on husbands is less pronounced.
Researchers found M. catarrhalis responsible for 10% of COPD exacerbations, with potential to develop vaccines to prevent infections in patients. The study involved 104 adults with COPD and identified 120 episodes of M. catarrhalis infections associated with flare-ups.
A team of researchers has developed a high-throughput method using GFT-NMR to solve protein structures in just 10-20 days per protein. This breakthrough could lead to major advancements in structural biology, enabling the study of membrane proteins and developing new medicines.
New research from University at Buffalo biologists found that female butterflies are attracted to the sparkle created by ultraviolet reflectivity of pupils in male butterfly wings, not the size of the eyespots. Females prefer a set of narrowly defined features, such as eyespot pupils measuring approximately half a millimeter.
A recent study found that living near a casino increases the risk of problem gambling, with a 90% increase in odds for those within 10 miles. Social and environmental influences also play a role, with respondents from disadvantaged neighborhoods reporting higher rates of problem gambling.
A study by Thomas H. Feeley found that 80% of college students want to learn more about organ donation, and 57 have signed up. However, only 11% of the total student population has done so. The researchers suggest tailoring information campaigns to address different segments of the student population.
Research found that premenopausal women with higher birth weights (above 8.5 pounds) and those who were not breastfed as infants have an almost two-fold increased risk of developing breast cancer. Breastfeeding during infancy was found to be protective against breast cancer in these high-risk groups.
A new search engine, Unintended Information Revelation (UIR), has been developed to uncover hidden information within documents. It uses concept chain graphs to find connections between seemingly unrelated concepts and can reveal sensitive data.
Researchers found that combining methylphenidate patch with behavior modification was superior to either treatment alone, achieving greater improvement in child behavior. The study also showed significant reductions in medication dosages needed, making it ideal for administering lower doses over time.
Researchers successfully amplify a phenomenon predicted by computer simulations, challenging the idea that equilibrium states are impossible in nonlinear systems. The discovery also sheds new light on the Young's modulus of materials.
A study found that exposure to traffic emissions at menarche (first menstrual period) and first birth was associated with increased breast cancer risk in premenopausal and postmenopausal women, respectively. The findings support the hypothesis that early-life exposures contribute to breast cancer risk.
Researchers found that rat fetuses exposed to a high-carbohydrate diet in utero developed increased insulin levels, appetite stimulation, and obesity. The study suggests that such malprogramming could be interrupted if the mother's weight and insulin levels are normalized before pregnancy.
A survey of 415 senior citizens in Western New York found that more than half faced barriers to seeing a dentist, with finances and anxiety being major concerns. The study suggests that dentists should discuss these barriers with their patients to improve access to dental care.
Histatin binds to TRK1p membrane protein, regulating potassium ion flow and killing fungal cells by preventing ion regulation. The finding paves the way for developing a more effective Candidiasis drug.
A new study by University at Buffalo researchers found that panoramic X-rays have limited value and can be used selectively in some cases. The study, which evaluated 1,000 panoramic X-rays, revealed that lesions in sinus cavities, soft tissue of the neck, and upper jaw bone were not always picked up on full-mouth-series X-rays.
A new study suggests that PET scanning is more accurate than SPECT in detecting heart disease, leading to a significant decrease in the use of invasive procedures like angiograms and bypass surgery. This could result in cost savings of up to 25% for patients managed with PET scanning.
A new study suggests that ingestion of afterbirth may modify specific opioid-receptor systems in the brain, facilitating the onset of maternal behavior. The research, led by UB professor Mark Kristal, aims to determine how endogenous opioid activation during pregnancy and delivery influences maternal behavior.
A novel sensor has been developed to measure tiny changes in cell volume, providing real-time results for antibiotic sensitivity testing. The technology, known as 'cell volume cytometry,' is highly sensitive and can detect changes in cell dimensions never seen before in living cells.
Researchers have developed an efficient new strategy to synthesize a natural marine product with promising anti-tuberculosis activity, overcoming challenges of conventional chemistry. The breakthrough enables the production of gram quantities in just days, paving the way for developing potential anti-inflammatory and anticancer agents.
Researchers at the University at Buffalo are conducting a 12-week study to evaluate the effectiveness of an amino acid supplement in reducing hot flashes in postmenopausal women. The trial will compare the active treatment with a placebo, and results may offer an alternative to hormone replacement therapy.