Researchers at University at Buffalo and Italy's University of Trieste found a potential link between Epstein-Barr virus (EBV) infection and the severity of multiple sclerosis (MS). Higher levels of anti-EBV antibodies were associated with increased loss of gray matter and total brain volume over time.
Researchers at University at Buffalo link capsaicin's analgesic effects to PIP2 lipid in cell membranes. The receptor's adaptation property allows it to continuously respond to varying stimuli, providing a novel strategy for developing safe pain-relieving medications.
A four-year prospective cohort study will examine the cognitive and affective consequences of traumatic brain injury (TBI) in Iraq and Afghanistan-era veterans. The study aims to provide evidence-based understanding of TBI's impact on veterans' quality of life, health care use, and community participation.
SnowMan, developed by UB engineers, uses fluid mechanics principles to design roadways less prone to snow drifts. The software provides precise placement of snow fences to mitigate drifting, reducing highway safety risks and winter maintenance costs.
A new IBS treatment developed at University at Buffalo has received $8.5 million to conduct a seven-year, multi-site clinical trial of the program. The trial will test the long-term effectiveness of a self-administered cognitive behavior therapy program and assess its impact on quality of life.
Researchers found that fetuses of obese mother rats developed obesity in adulthood due to altered energy homeostasis and hormone levels. The study suggests that women maintaining optimal conditions during pregnancy may be crucial in preventing adult-onset obesity.
The study uses a systems biology approach to understand carbohydrate structures in cells, leading to new ways to combat inflammatory illnesses. Researchers aim to define novel strategies to perturb the glycome and identify new targets for molecular therapies.
Parents of a child with ADHD nearly twice as likely to divorce by age 8 compared to parents without ADHD. Marriages involving children with ADHD ended sooner than those without ADHD.
A decade-long study by University at Buffalo researchers investigates the physical and mental health effects of policing, revealing high risks of coronary events, cholesterol levels, pulse rates, and diastolic blood pressure. The study also examines shift work's impact on stress and suicide risk in police officers.
A study published in Diabetes Care found that young men with type-2 diabetes have significantly lower levels of testosterone, which can impact fertility, muscle development, and increase the risk of heart disease. The study also highlights the potential clinical implications of low testosterone in these individuals.
A study found that frequent energy drink consumption is associated with increased risk of substance use, unsafe sexual activity, and other forms of risk-taking among college students. Energy drink consumption may serve as a screening indicator for identifying students at risk for problem behavior syndrome.
A new pilot study has shown that a self-administered, at-home cognitive behavioral program can relieve IBS symptoms comparable to office-based therapy. The findings are significant because there are no reliable medicines available to treat the full range of IBS symptoms.
A special issue of International Journal of Forecasting explores various election forecasting models, including those using political futures markets and historical analysis. Researchers discuss the importance of campaign effects and the limitations of predicting outcomes without an incumbent candidate.
A new study found that people who choose not to express their thoughts and feelings after experiencing a collective trauma, such as a school shooting or terrorist attack, may be better off than those who do talk about their feelings. The research suggests that it's okay to keep emotions inside in the immediate aftermath of a tragedy.
A recent study reveals that approximately 2.1% of US youth aged 14-21 exhibit problem gambling behaviors, projecting to around 750,000 young problem gamblers nationwide. The study also found significant correlations between increased gambling involvement and transitioning into adulthood.
Two studies from the University at Buffalo use advanced MRI technologies to identify brain regions linked to Parkinson's disease. The research found that white matter hyperintensities are associated with lower scores on mental tests, suggesting a possible explanation for cognitive impairment in PD.
Researchers at University at Buffalo have found that people with periodontitis who are infected with human papillomavirus (HPV) are at increased risk of developing tongue cancer. The study showed that 63% of patients with tongue cancer also had periodontitis, and 90% of those without HPV also did not have periodontitis.
Researchers have discovered that stem cells isolated from hair follicles can differentiate into smooth muscle cells that grow new vasculature, making them ideal for engineering cardiovascular tissue regeneration. This breakthrough may lead to the development of new treatments for vascular grafts and cardiac tissue regeneration.
Researchers at the University at Buffalo found that taking ibuprofen while taking aspirin for stroke prevention reduces its effectiveness. In a study of 28 patients, all took ibuprofen and had no anti-platelet effect from their daily aspirin.
A study found that restricting children's video time by using a device reduced their BMI significantly over two years. The intervention group showed a steady decline in BMI, while the control group showed an increase followed by a decline.
The BioBlower technology has passed US Department of Defense tests and has been directed to retrofit military platforms with the system. The device destroys airborne pathogens by rapidly heating and compressing contaminated air, providing a more efficient and effective solution than conventional HEPA filters.
Researchers at the University at Buffalo found that up to 20% of patients taking aspirin for stroke and heart attack prevention do not respond to the medication, leading to increased risk of clinical failure. The study also identified factors associated with aspirin resistance, including younger age and underlying vascular disease.
A recent study documents various stigmatizing behaviors by health-care personnel towards HIV-positive patients, including lack of eye contact, disdainful voice tone, and providing substandard care. The study highlights the need for all health-care personnel to be mindful of their actions to prevent misunderstandings and hard feelings.
Researchers used digital imaging techniques to document Greenland's ice sheet dynamics and found significant changes in the glacier's geometry without visible calving events. The new data can impact climate projections and sea-level rise estimates, possibly doubling current projections.
A study found that young women who increased their drinking during the high school-to-college transition were more likely to experience physical and sexual victimization. The majority of freshmen women did not experience any victimization, but those who drank alcohol had substantially higher rates of physical and sexual assault.
Researchers at University at Buffalo found that Celebrex reduces heart rate and induces arrhythmia by inhibiting potassium channels, which are present in the heart, brain, and other tissues. The study suggests that the drug's mechanism of action may be relevant to its cardiovascular side effects.
A new chemical synthesis method based on a rhodium-based catalyst has the potential to dramatically improve the design and production of new drugs. The catalyst can produce large quantities of pharmaceutical products with unprecedented structural entities, making it an enabling technology for drug discovery.
A recent study by University at Buffalo biologists provides the most complete picture to date of the complex biological mechanisms of bacterial viruses infected with Shiga toxin. The research reveals that toxins like Shiga are used by bacteria to become mobile and can lead to more effective treatments for humans infected with it.
A recent study found that electronic patient tracking systems can affect how healthcare providers communicate information and track activities, leading to inefficiencies and workarounds. The manual whiteboard-based system allowed for flexibility in tracking patients, but the computerized system lacked this flexibility, requiring provid...
Researchers at the University at Buffalo are investigating the effectiveness of mindfulness-based stress reduction (MBSR) in treating alcohol dependence. The four-year study aims to develop an increased ability to cope with stress and enhance psychological well-being among alcohol-dependent individuals.
Detailed statistics show that 82% of parents accurately evaluated cigarette smoking, 86% accurately reported alcohol use, and 86% accurately reported marijuana use. However, only 72% accurately reported illicit drug use. Parents can use this knowledge to help themselves cope with teenage substance use.
Researchers found that severely restricting calories can maintain physical fitness into advanced age, reducing visceral fat and improving overall physical function assessments. This approach may slow the progression to physical disability and loss of independence.
Researchers have discovered that cigarette smoking increases brain tissue shrinkage and disease severity in multiple sclerosis patients. The study used MRI scans to compare smokers and nonsmokers with MS, finding significant differences in disability scores and brain volume.
A large group of MS patients with a family history showed more severe brain damage, including more lesions and gray matter damage, compared to those without a family history. This study suggests that genetic factors play a role in disease severity.
Researchers at the University at Buffalo study brain signals and animal models to find tinnitus relief; goal is to identify neural signature of the condition. Potential therapies are being tested using radioactive tracers and unique compounds.
Researchers at University at Buffalo develop automated system to track individuals' likelihood of committing a terrorist act based on biometrics and behavioral indicators. The system aims to identify perpetrators in real-time, providing a numerical score of malfeasance likelihood.
Researchers have developed a novel device that can trap, detect and manipulate the spin of a single electron, overcoming major obstacles in spintronics and quantum computing. The device uses quantum point contacts to steer electrical current and detect trapped spins.
A new study by University at Buffalo researchers found that extreme cherry pickers barely affected retailer profits, with only 1.2% of grocery store customers engaged in this behavior. These 'extreme' shoppers saved an average of 76% of potential savings through their shopping strategies.
Nurses describe competing priorities, balancing family needs, and practicing deterrents such as pay inequity and lack of respect. However, collegial support emerges as a crucial factor in maintaining their dedication to the profession.
University at Buffalo researchers have made significant breakthroughs in genetic engineering of micro-organisms into cellular factories, enabling the production of high-value chemicals and pharmaceutical compounds. The team has successfully produced flavonoids with yields far above previous microbial synthesis efforts.
A new study by University at Buffalo's Research Institute on Addictions found a strong correlation between malt liquor consumption and marijuana use. Young adults who drink malt liquor are more likely to develop alcohol problems and use illicit drugs.
UB researchers discover that certain solvents can significantly impact acid-base interactions, strengthening chemical bonds between molecules. The study suggests a new tool for initiating these interactions in important biological enzymes.
Researchers at the University at Buffalo have found that copper absorption increases when iron levels decrease, suggesting a crucial role for copper in maintaining iron homeostasis. The study aims to understand the molecular mechanisms behind this relationship and its implications for human health.
A study by University at Buffalo endocrinologists found that flavonoids in orange juice suppress destructive oxygen free radicals, reducing oxidative stress and inflammation in healthy participants. The two types of flavonoids, hesperetin and naringenin, inhibited ROS generation by 52% and 77%, respectively.
A randomized clinical trial found that selenium supplementation increased the risk of developing type 2 diabetes by 55%, with higher levels associated with a greater risk. The study suggests that taking high doses of selenium may have detrimental effects in well-nourished populations.
Researchers at Hauptman-Woodward Institute have solved the structure of a novel protein in Pseudomonas, a bacterium that causes cystic fibrosis and tuberculosis. The discovery may lead to the development of new antibiotics to prevent infection in patients with CF and TB.
A 19-year study found that primate tourism practices can lead to adult aggression, disease transmission, and increased infant mortality. The study suggests that range restriction and provisioning for tourists contribute to the problem, making them an inappropriate management strategy.
Researchers at University at Buffalo developed a method to isolate functional smooth muscle cells from bone marrow, which can be used in regenerative medicine for cardiovascular applications. The engineered blood vessels function similarly to native tissue, demonstrating potential as an alternative to venous grafts.
Researchers at the University at Buffalo discovered that high levels of cystatin C can predict an increased risk of developing pre-diabetes. The study, based on the Western New York Health Study, found a three-fold association between cystatin C levels and progression to pre-diabetes.
A new study suggests that women who suffer from morning sickness during pregnancy may be less likely to develop breast cancer later in life. The study found a 30% lower risk of breast cancer among women with nausea and vomiting compared to those without, suggesting potential protective effects against cancer cells.