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University of California - Berkeley


Cancer vaccine based on pathogenic listeria bacteria shows promise targeting metastases

A genetically engineered listeria bacteria-based vaccine has shown promising results in targeting metastatic cancer cells, inducing a strong innate and acquired immune response. The vaccine, aiming to target pancreatic and ovarian cancers, could potentially be used to prevent recurrence after surgery and chemotherapy.

SourceUniversity of California - Berkeley·JournalProceedings of the National Academy of Sciences·DateSep 29, 2004

When is a mouse like a test tube?

Researchers use a novel chemical reaction in living mice to tag cells and attach tracer molecules to sugars on cell surfaces. This technique could help doctors pinpoint inflamed or cancerous cells for diagnosis. The method allows for the exploration of biosynthetic pathways and the examination of functional consequences.

Dramatic decline of California native frog linked to introduced trout in mountain lakes

A study by UC Berkeley post-doctoral fellow Vance T. Vredenburg shows that non-native trout have devastated native frog populations in high-Sierra lakes, but removing fish allows the frogs to flourish. The mountain yellow-legged frog has declined dramatically due to introduced trout, with only 5,000 adults remaining in its range.

SourceUniversity of California - Berkeley·JournalProceedings of the National Academy of Sciences·DateMay 12, 2004

Bighorn sheep threatened by climate change

A study published in Conservation Biology found that climate change is consistently correlated with extinction among desert bighorn sheep. The researchers identified higher temperatures and decreased precipitation as key factors contributing to the decline of these populations, which are already living on a knife's edge.

SourceUniversity of California - Berkeley·JournalConservation Biology·DateFeb 11, 2004