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University of Florida


Scientists get look at genes' defensive playbook

Researchers analyzed gene activity in volunteers exposed to a bacterial product, identifying previously unknown relationships among genes involved in blood cell responses to infection. The study provides valuable insights into the human genomic response to inflammation, which can be fatal in severely burned or injured patients.

SourceUniversity of Florida·JournalNature·DateAug 31, 2005

Micro-molecule plays big role in birth defects

Scientists with the UF Genetics Institute found that eliminating microRNAs from specific tissues can reveal their vital role in healthy development. The technique may provide insight into human birth defects and has potential applications in studying the function and malfunction of microRNAs, a crucial part of human gene expression.

SourceUniversity of Florida·JournalProceedings of the National Academy of Sciences·DateJul 19, 2005

Manatee eyes could be window to health status

Scientists are exploring the relationship between manatee tears and blood vessel formation to better understand the animals' immune system. The study found that manatees have a thick, mucusy tear film rich in antimicrobial components, which may help protect against pathogens.

SourceUniversity of Florida·JournalVeterinary Ophthalmology·DateJun 21, 2005

For first time, brain cells generated in a dish

Researchers at the University of Florida have successfully generated brain cells in a dish, a breakthrough that could lead to new treatments for neurological disorders. The discovery identifies the true stem cell, which can be used to produce a limitless supply of brain cells to potentially heal damaged brain function.

SourceUniversity of Florida·JournalProceedings of the National Academy of Sciences·DateJun 13, 2005

Epilepsy by the numbers

Researchers have developed a mathematical way to translate brain wave readings into simple terms to help doctors identify newborns at risk for epilepsy. The new tool uses quantitative EEG analysis to pinpoint abnormal brain activity in real-time.

Exercise in cold water may increase appetite, UF study finds

Researchers found that exercising in cold water led to a 44% higher caloric intake compared to warm water or resting periods. The study suggests that environmental conditions during exercise may influence post-exercise appetite, and individuals should consider the kinds of foods they eat after exercise.

SourceUniversity of Florida·JournalInternational Journal of Sport Nutrition and Exercise Metabolism·DateMay 4, 2005

New drugs for bad bugs

University of Florida researchers have developed a patent-pending method to improve antibiotic development, combining testing of various drug concentrations at the site of infection with laboratory analyses and mathematical models. This approach aims to reduce the lengthy and expensive trial-and-error process that can take years.

No blind mice, thanks to UF scientists

Researchers successfully silenced SDF-1's signal in mice with simulated retinopathy, effectively halting the growth of new blood vessels. The study could lead to a treatment option using routine injections of an antibody-blocking substance into a patient's eye.

SourceUniversity of Florida·JournalJournal of Clinical Investigation·DateJan 6, 2005