A University of Manchester engineer has pioneered a way to make single-layered planar plastic transistors and diodes using fast and simple printing techniques. This could lead to the production of information displays that can be rolled up, intelligent tickets for public transport systems, and electronic stamps for letters and packages.
Scientists have developed tiny gel particles that can be injected into damaged intervertebral discs to restore mechanical properties and regain mobility. The 'microgels' have the potential to offer a non-surgical alternative to spinal fusion surgery, reducing recovery time and preserving disc flexibility.
Scientists have discovered that anti-fungal drugs can kill the TB bacteria, potentially effective against emerging drug-resistant strains. The study found that chemicals called azoles target a specific enzyme in the TB bacterium, leading to its death.
Researchers at The University of Manchester have developed a new type of technology using the world's thinnest material, which can be used to sieve gases and make ultra-fast electronic switches. The discovery has significant implications for the development of medical drugs, as it will potentially allow the rapid analysis of atomic str...
Researchers at the University of Manchester have developed a new type of transistor made from graphene, which is only one atom thick and less than 50 atoms wide. This innovation could lead to the development of faster computer chips by allowing for the rapid miniaturization of electronics.
Researchers in Manchester and London are working on a £1.5m project to create more efficient solar cells using inexpensive materials and novel fabrication methods. The goal is to produce demonstration hybrid solar cells with the potential to be mass-produced and achieve an energy conversion efficiency of ten percent.
A genome-wide study of 1,200 families with multiple cases of autism has identified a previously unidentified region on chromosome 11 and implicated genes affecting glutamate neurons. The findings provide new insights into the genetic basis of autism and offer potential routes to breakthroughs in treatments.
A major 20-year study has cast doubt on the assumption that orthodontic treatment improves psychological well-being. The study found that orthodontic treatment had little positive impact on participants' psychological health and quality of life in adulthood, contradicting widespread beliefs among dentists.
Scientists have uncovered the molecular structure of cartilage's collagen fibrils, a key factor in osteoarthritis. The discovery could lead to treatments that prevent fibril deterioration and ultimately alleviate joint pain.
Researchers have developed an automated method to identify osteoporosis sufferers in routine dental x-rays, which could help diagnose the disease earlier. The software measures jaw cortex widths, alerting dentists to potential cases, with a success rate comparable to specialist consultants.
A study by the Human Pain Research Group at the University of Manchester found that individuals' expectations and beliefs play a crucial role in their response to pain relief. The researchers discovered that 67% of volunteers who expected pain relief continued to perceive less pain after applying a placebo cream, highlighting the power...
Research led by the National Drug Evidence Centre found that problem drug use is declining in some areas previously considered 'hot spots' in the UK. The study suggests that younger people are being recruited into the problem drug use population at a faster rate, leading to a decline in incidence rates.
Researchers have identified a new key step in how the Polo kinase enzyme functions, confirming its potential as a target for anti-cancer drug development. The study sheds light on how the enzyme helps cells divide and multiply in an uncontrolled manner to form tumors.
Dr Nigel W Brown's Aquacart system uses Nyex material to remove toxic organic contaminants from wastewater, promising a solution to global water pollution concerns. The technology has the potential to meet challenges of new legislation and be applied to various industrial processes.
A study found that schizophrenia patients respond equally well to older psychiatric drugs as newer, costlier alternatives. The NHS-funded trial revealed little benefit from switching to second-generation anti-psychotics despite their higher market share.
A new genetic theory suggests that certain offspring characteristics can only be explained by genetic cooperation between maternal and paternal genes. This challenges the prevailing view of a parental power struggle, instead proposing that positive interactions between mothers and their offspring drive imprinting patterns.
Researchers at the University of Manchester have discovered that Manchester commuters inhale their biggest daily dose of harmful traffic fumes during the morning rush hour. The air pollution traps particles near ground level, which can be toxic to human health.
The University of Manchester will develop innovative new counter-terrorism technologies using £multi-million pounds in funding from the Home Office. The project aims to improve detection, identification and decontamination of chemical, biological and radiological materials.
The University of Manchester won a $500,000 prize for its innovative approach to knowledge transfer and collaboration with industry. The university's Faculty of Engineering and Physical Sciences was awarded the grant to support concept studies, short projects, and an incubator scheme for companies.
The University of Manchester and University of Sheffield are using interactive video conferencing to improve the teaching of mathematics to PhD students. The project aims to provide a broader and deeper knowledge of math, enabling students to compete with international peers for key jobs and positions.
Researchers at the University of Manchester have made a breakthrough in developing a new class of cancer drugs that target the Aurora B enzyme, which helps cells divide and can lead to uncontrolled cell growth in cancer. Early clinical trials suggest the drug's toxicity is mild, offering a revolutionary new way to treat cancer.
Researchers identified IRF6 as a key gene causing cleft lip and palate disorders. The team also discovered that targeting this gene during pregnancy could lead to normal skin cell development.
Researchers at The University of Manchester are developing new techniques using cultured human cells to identify carcinogens and reduce the need for animal testing. The project aims to increase confidence in pre-animal tests and minimize false positives.
Early mammals' eyes have only one version of the photoreceptor gene that detects light, unlike birds, fish, and amphibians with two versions. This suggests they may have been nocturnal creatures.
Researchers identified three proteins that determine an individual's hair pattern during embryonic development. They also found that hyperactivating one of these proteins in mice led to abnormal fur growth, providing insights into male-pattern baldness and ectodermal dysplasia.
Researchers have identified three genetic variants associated with an increased risk of cot death, also known as SIDS. The study found that babies born with these specific variants are up to 14 times more likely to die from the condition.
Researchers at the University of Manchester have developed a topical treatment against human papilloma virus (HPV) that could potentially prevent cervical cancer. The treatment uses a protease inhibitor already licensed for oral administration, which can selectively kill HPV-infected cells when applied directly to the cervix.
Researchers found that taller, faster-growing children are more vulnerable to the effects of an obesogenic environment. The study, which surveyed 50,000 three-year-olds, showed a strong relationship between child growth and obesity.
Researchers created a 3D computer simulation to mimic the complex process of reopening collapsed airways. The study found that 'fluid inertia' plays a crucial role in assessing the pressure required to reopen blocked airways, which is essential for preventing lung damage.
Researchers aim to understand how complex visual scenes are encoded by the brain using a new computer model. The computer will mimic nerve cell interactions and track patterns of neural spikes in real-time.
Researchers are developing drugs called Allergen Delivery Inhibitors (ADIs) to stop allergens from entering the body. These ADIs promise to be significantly better than current treatments, which only ease symptoms rather than preventing allergic reactions.
A new theory suggests that two-thirds of people diagnosed with schizophrenia have suffered physical or sexual abuse, making it a major cause of the illness. The research argues that trauma, not just genetic predisposition, contributes to schizophrenic symptoms.
A University of Manchester team has discovered a protein potentially involved in the spread of tumors. The researchers believe their findings could lead to new approaches to treating breast cancer by blocking the protein's actions.
Researchers have discovered a connection between a protein that prevents cancer in humans and lifespan in nematode worms, suggesting that this protein may determine how long we live. The 'checkpoint proteins' also appear to play a role in cell division and could be used to develop new strategies for treating neurodegenerative diseases.
Scientists at the University of Manchester have identified a previously unknown mechanism by which glucose blocks brain cells responsible for regulating wakefulness. This finding has implications for understanding and treating disorders such as narcolepsy, obesity, and addiction.
A novel therapeutic approach has been discovered by the University of Manchester team, using a DNA-binding protein to stimulate genes and promote nerve growth. The preclinical results have been encouraging, with initial-stage clinical trials in the US showing promising progress in managing diabetic neuropathy.
Researchers at the University of Manchester are investigating molecular mechanisms behind retinoschisis to find a cure. They will build on existing research to develop new treatments and diagnostic tests for this genetic disorder.
Researchers at the University of Manchester have identified seawater in volcanic gas samples from the Earth's mantle, supporting the theory that seawater is subducted deep into the Earth. The study reveals that up to 10% of the Earth's oceans have been absorbed into the planet since its formation.
Scientists have made significant breakthroughs in understanding how proteins are transported across cell membranes, a process fundamental to all living organisms. The findings could lead to new insights into the treatment of type-2 diabetes and other diseases.
Researchers have provided new insight into enzyme function through detailed experimental observations and theoretical analysis. Their findings suggest that enzymes use quantum mechanical tunnelling to overcome energy barriers, which could lead to improved pharmaceuticals and manufacturing processes.
A new wound monitor uses hybrid sensor technology to detect bad bacteria in the air emitted from a wound, enabling rapid and non-invasive infection diagnosis. The device aims to improve early detection of infections, reducing discomfort for patients with severe burns, skin ulcers, or gaping wounds.
Researchers at the University of Manchester have created a new bio-gel for 3D cell culture that mimics natural cell scaffolds. The gel, made from dipeptides, has potential applications in wound healing and regenerative medicine.
A study of fossilized spiders from the Baltic and Dominican regions provides new insights into ancient spider ecologies. The research found that web-spinning spiders were larger in Baltic amber than in Dominican amber, with the size difference attributed to the type of trees in each region.
A recent study found that 67% of teenage and young adult cancer patients successfully banked their sperm, despite initial obstacles such as anxiety and lack of knowledge. The researchers emphasized the importance of incorporating fertility preservation into treatment plans for these patients.
Researchers have found a naturally occurring mutant chicken called Talpid with a complete set of teeth, similar to those of crocodiles. The team successfully induced teeth growth in normal chickens by activating dormant genes, paving the way for potential applications in tissue regeneration and tooth replacement.
The device uses four sensors to analyze air composition and alert waste management companies to methane gas and odor levels, creating a healthier environment for local communities.
Researchers have identified genome sequences for three species of Aspergillus fungus, shedding light on their role in disease and potential for new treatments. The findings may help develop diagnostic tests and prevent allergies and diseases like pneumonia and sinusitis.
A £6m grant has been awarded to develop new methods for processing, forming, joining, and surface engineering of aluminium, titanium, and magnesium. The project aims to create lighter, more environmentally-friendly vehicles using these materials.
A team of scientists has successfully created a new material that induces magnetic vibrations at visible light frequencies, allowing for the creation of ultra-small optical lenses and miniature lasers. This breakthrough could lead to significant advancements in optics, optoelectronics, and biosensing.
Researchers have successfully tested Einstein's relativity theory using ultra-thin Graphene, a material created by extracting graphite via pencil-tracing. This breakthrough enables direct experiments to test relativistic ideas, potentially leading to groundbreaking discoveries.