University of Manchester researchers have received £1.6 million in funding to study a group of genes identified as playing a key role in leukaemia. The grant will help analyze the common mechanisms of action for patient benefit, potentially leading to the development of targeted therapies.
Researchers confirmed Einstein's theory of general relativity using observations of a unique pulsar system. The discovery shows that one pulsar is 'wobbling' in space, a effect precisely as predicted by Einstein.
Researchers at the University of Manchester found that able-bodied mobile users replicate errors made by physically impaired desktop computer users, such as pressing wrong keys and clicking incorrectly. The study suggests that software solutions developed for disabled users can be applied to reduce errors on mobile devices.
The University of Manchester will lead a joint planning phase for the Biobanking and Biomolecular Resources Research Infrastructure, linking European biobanks and managing millions of biological samples. The project aims to counter fragmentation in Europe and facilitate access to valuable resources for biomedical research.
A five-year clinical trial has shown that computer-assisted dosage of blood thinning drugs is at least as safe and reliable as those provided by expert medical professionals. The study involved over 13,000 patients and nearly 400,000 INR tests, confirming the effectiveness of computer-assisted dosage.
Research published by The University of Manchester's National Confidential Inquiry into Suicide and Homicide by People with Mental Illness reveals a significant link between alcohol and drug misuse and Scottish suicide and homicide rates. The study found that Scots are almost twice as likely to kill or take their own lives compared to ...
Scientists are using a powerful supercomputer to create a model of normal human language that can read, comprehend, and repeat basic words. The 'Chatter Box' project aims to understand how the brain supports language function and how it breaks down after brain damage.
Large brown seaweeds release inorganic iodine when stressed, contributing to cloud formation and altering coastal climate. This process may lead to 'thicker' clouds with reduced rainfall and a moodier coastal skyline.
Researchers at the University of Manchester have developed tiny liquid crystal devices with graphene electrodes, paving the way for computer and TV displays based on this technology. The graphene-based films are highly transparent and conductive, making them ideal for applications in various electro-optical devices.
Researchers at the University of Manchester found that carrying infants was unlikely to have driven human evolution towards walking upright. Instead, they suggest that this characteristic may have been an adaptation for other benefits, such as freeing up forelimbs to carry objects.
Researchers from the University of Manchester have successfully created the world's smallest transistor using graphene, a one-atom-thick material. The breakthrough paves the way for significant advancements in nanoelectronics and could potentially solve the scaling limitations of traditional electronics.
Scientists have discovered a way to genetically manipulate embryonic stem cells into insulin-producing pancreatic tissue, potentially treating type-1 and type-2 diabetes. The team found that the transcription factor PAX4 encouraged high numbers of stem cells to become beta cells with insulin-producing capabilities.
A new study reveals that some individuals, like slime moulds, are genetically programmed to cheat and benefit from it. In a complex evolutionary arms race, cheaters thrive when non-cheaters fail.
Researchers at the University of Manchester have successfully treated mice with Treacher Collins syndrome, a rare genetic disorder, by preventing premature cell death. The breakthrough could lead to early treatment of at-risk babies in the womb.
Researchers at the University of Manchester are using zebrafish to investigate the causes of Lowe syndrome, a rare genetic disorder affecting only boys. The team aims to identify key factors, including the gene OCRL1, and explore potential treatments for the condition.
A new study published in Nature Genetics reveals that diet and lifestyle can significantly impact the effectiveness of certain drugs, including those used for cancer therapies. The research found that nutrient availability can either enhance or harm cell fitness, depending on the surrounding environment.
A recent study on the burying beetle found that parents instinctively favor older offspring, leading to unequal growth rates among siblings. The researchers believe this bias is due to both increased survival value and dominance in younger siblings.
Researchers at the University of Manchester have pioneered new methods to modify antibiotics' molecular structure, enabling the development of new types of antibiotics capable of combating increasingly resistant bacteria. This innovation provides access to thousands of lipopeptide variants that cannot be produced easily in any other way.
A University of Manchester team discovered that theropod dinosaurs had avian-like air-sac respiratory systems, allowing for efficient oxygen supply. This finding supports the theory that dinosaurs were direct ancestors of birds and had similar characteristics.
Researchers at the University of Manchester have identified a genetic variant on chromosome 6 associated with rheumatoid arthritis. The discovery may influence the behavior of a nearby gene, tumour necrosis factor associated protein (TNFAIP3), which is involved in inflammatory processes.
A 53-million-year-old fossilized spider has been digitally dissected using VHR-CT, revealing internal organs for the first time. The technique has revolutionized the study of amber fossils, providing a unique window into past forest ecosystems.
A new study is working to save the endangered splendid leaf frog by understanding its development and behavior in relation to diet and environment. The researchers are conducting field studies and experiments at Chester Zoo to provide a better idea of the species' nutritional requirements.
Researchers at the University of Manchester examined St Bernard skulls over 120 years and found features that became more exaggerated as breeders selected for desired physical attributes. This suggests sustained evolutionary change under known selective pressures.
Scientists have identified a key gene called Bub 1 that plays a critical role in normal cell division, and deactivating it has been shown to prevent cells from dividing successfully. The team hopes that targeting this gene may selectively kill cancer cells and develop new treatments.
The UK is considering vaccinating schoolgirls against the Human Papilloma Virus (HPV) to prevent cervical cancer. A pilot study led by the University of Manchester aims to assess the acceptability and feasibility of a three-dose vaccine, Cervarix.
A study aims to identify genetic variations associated with radiotherapy side effects, enabling individualized treatment. The research hopes to reduce toxicity while maintaining tumour control.
Researchers have discovered that Notch gene stimulates breast cancer stem cells, which can cause the disease to recur. A potential new drug therapy targeting this gene could lead to a faster treatment in hospital clinics within a few years.
A new method using microwaves can determine the fat content of beef and other meat products, offering a fast and non-invasive alternative to current methods. The technology has potential to reduce waste, save energy, and improve food safety in the industry.
The University of Manchester is leading UK involvement in the £1.1 billion Square Kilometre Array project, which will create a detailed map of the sky and allow astronomers to test Einstein's theory of relativity and search for signs of alien life.
Researchers propose that early humans used efficient bipedal walking rather than chimp-like 'Groucho' walking. Without an Achilles tendon, their ability to run would be severely compromised, with top speeds halved and energy costs more than doubled.
A new study is providing highly successful parenting skills to parents with bipolar disorder, using the Triple P Positive Parenting Programme. The program has been shown to improve behavior in children and increase parental confidence, particularly for those experiencing instability of mood and behavior.
Researchers are working on a £18 million project to change the social habits of living cells, which could help fight diseases like cancer and diabetes. By adjusting cell networking, they aim to reduce disease occurrence and improve health outcomes.
Researchers have developed a laser-based device to measure carbon dioxide, carbon monoxide, and methane emissions directly from vehicle exhausts. This technology has the potential to monitor emissions in real-time, enabling drivers to adjust their driving style and reduce pollution.
Researchers have created graphene-based devices that can detect individual molecules of a toxic gas, offering potential applications for detecting hidden explosives and deadly carbon monoxide. The discovery was made by Dr Kostya Novoselov and Professor Andre Geim at the University of Manchester.
Researchers at the University of Manchester have uncovered the structure of a key pain molecule, P2X receptors, using microscopic slime moulds. This breakthrough could lead to the development of new painkillers for chronic conditions like migraine and backache.
A new invention, Gasclam, can continuously monitor underground methane levels, allowing for more efficient brownfield development. This technology could lead to increased construction on previously restricted sites.
A survey of 401 oncology registrars found that 102 experienced psychiatric morbidity, with depression being a major concern. The study suggests that better support and supervision can alleviate stress and improve performance.
University of Manchester researchers have identified evidence of several new genes behind rheumatoid arthritis (RA), a chronic inflammatory disease that affects nearly all joints. The study, part of the largest ever genetics study, has provided insights into what leads people to develop RA and offers new avenues for treatments.
Researchers at the University of Manchester are developing tools to adapt urban landscapes to heat islands, aiming to increase human comfort and reduce harmful carbon emissions. The SCORCHIO project will provide a detailed picture of how urban 'heat islands' impact temperatures during hot months.
An international team of researchers has been awarded £2 million to study the genetic causes of dwarfism and develop future treatments. The EuroGrow project aims to investigate the most common bone disorders that lead to short stature, with a focus on achondroplasia, pseudoachondroplasia, and spondyloepiphyseal dysplasia congenita.
Researchers used embryonic stem cells to investigate how some tumours migrate to other parts of the body, making treatment more difficult. They found that a crucial change in cell behavior, known as epithelial-mesenchymal transition, allows cancer cells to move and spread.
The University of Manchester is establishing a £3 million research centre to develop fundamental knowledge and techniques for complex systems with discrete and continuous interactions. Researchers aim to create new prediction methods that can be applied in areas like aircraft control and car safety systems.
A 10% increase in urban green space could reduce surface temperatures by as much as 4°C, effectively 'climate proofing' cities. However, this may not significantly impact the amount of rainwater captured and retained by urban areas.
A team of scientists at the University of Manchester found evidence that ancient Egyptian physicians practised a credible form of pharmacy and medicine over 1,000 years before Hippocrates. The researchers discovered medicinal remedies such as honey, resins, and metals with therapeutic merit, many of which remain in use today.
Researchers at the University of Manchester used a laser scanning system to create a detailed 3D model of dinosaur tracks in Spain. The portable RIEGL LMS Z420i scanner allowed for rapid and high-resolution mapping of the fragile site, preserving important information on dinosaur locomotion.
Researchers at the University of Manchester have successfully treated diabetic patients with MRSA-contaminated foot ulcers using green bottle fly larvae. The study found that all but one patient were cured within three weeks, significantly shorter than conventional treatment.
Researchers are developing a new type of particle accelerator that could lead to more effective cancer treatment, greener electricity, and reduced nuclear waste. The CONFORM* project aims to build a non-scaling fixed field alternating gradient (NS-FFAG) accelerator, which has the potential to be used in medical applications, renewable ...
Researchers at the University of Manchester are developing low-cost LED lighting modules that can be used in buildings and on roads, offering a potential 25-50% reduction in energy consumption. The project aims to tackle thermal and electrical issues associated with high-powered LEDs.
A study by University of Manchester researchers reveals that arthritis pain activates the brain's emotional and fear centers, processing emotions and aversive conditioning. The findings suggest a more intense emotional response to arthritic pain compared to experimental pain.
Researchers at the University of Manchester found that older women with breast cancer receive lower levels of care compared to younger women. This includes reduced likelihoods of needle biopsy, surgery, and radiotherapy, which can lead to higher local recurrence rates and mortality.