Researchers discovered that TRPV3 plays a crucial role in regulating hair growth and skin health. The protein's activation leads to the release of TGF-alpha, which stimulates EGFR, forming a positive signaling loop.
Researchers are developing a computer inspired by the feline brain's ability to recognize faces and learn from experience. The project aims to create a machine that can perform tasks simultaneously, like recognizing faces, while conventional computers rely on sequential processing.
Researchers have taken the first close-up pictures of Epsilon Aurigae's mysterious dark companion, revealing a geometrically thin, dark, dense, but partially translucent cloud. The images show that the basic paradigm was right despite slim probability, and provide new insights into the system's shape and surface characteristics.
A new study found that middle-aged Americans aged 50-64 reported a significant increase in mobility-related difficulties, with over 40% citing health problems as causes. The trend is concerning, as it may lead to increased need for long-term care and societal costs.
A new study by University of Michigan scientists suggests that evolutionary genetic mechanisms underlying changes in form and function are distinct. Researchers found that genes affecting morphology (form) evolved faster than those affecting physiology (function), supporting the idea that morphological changes result from gene expressi...
New research suggests the Andes rose gradually, not abruptly, due to changes in oxygen isotopes and rainfall patterns. Climate modeling experiments supported this conclusion, indicating that increased precipitation rates caused the ratio of oxygen-18 to oxygen-16 to decrease.
Researchers discovered a nearly complete juvenile Diplodocus skull that reveals drastic changes in skull shape during normal growth. The discovery provides new insights into the feeding behavior of young Diplodocus, which may have been choosier browsers selecting high-quality plant parts.
Researchers are using thermography and endoscopy to examine the contents of a 1,000-pound lead coffin found in an ancient Italian city without breaking it. The discovery is significant due to its rarity, with only a handful of examples from this time period existing in Italy.
Researchers at the University of Michigan have developed mini generators that can produce electricity from random, non-periodic vibrations. These devices have the potential to power a range of applications, including remote wireless sensors and surgically implanted medical devices.
The spliceosome, a giant complex of RNA and protein subunits, assembles and operates to remove unwanted genetic material and join the remaining pieces. Researchers spied on the process using FRET and observed reversible contortions in the presence of energy.
University of Michigan engineers have found that light can cause rigid nanoparticles to twist into complex shapes. This discovery could lead to breakthroughs in superchiral materials, invisibility cloaks, and novel applications in drug delivery, microfluidics, and lithography.
Researchers at U-M have solved a long-standing mystery about how insulin-like growth factors (IGFs) work on muscle cells. IGFs promote either muscle cell differentiation or division, depending on oxygen availability.
Researchers found that sea urchins prey on crinoids, a type of marine animal known as sea lilies, and suggested that these interactions drove the development of motility in sea lilies. The study, published in PNAS, provides evidence for an evolutionary arms race between predators and prey dating back over 200 million years.
Researchers develop method to efficiently turn carbon dioxide into carbon monoxide using visible light, a process similar to what organisms naturally do. The technique has potential applications in producing electricity or hydrogen and could be scaled up with mass production of the catalyst.
University of Michigan researchers found a vulnerability in RSA authentication, a widely used encryption method. By manipulating voltage supply to the private key holder, hackers can extract the key and compromise security. The discovery has significant implications for media companies, mobile device manufacturers, and online retailers.
A study of corporate executives found that only 68% took their cholesterol-lowering medication as prescribed. Executives who took statins were twice as likely to meet their cholesterol goals and achieved better outcomes than those who didn't take the medication, even sporadically.
Researchers found that coastal and open-ocean fish have distinct mercury signatures, ruling out the idea that they pick up methylmercury by eating contaminated coastal fish. Instead, they suggest that mercury is deposited into the open ocean and undergoes methylation in low-oxygen microenvironments.
A team of researchers, including University of Michigan paleontologists, has discovered a new species of herbivorous sauropod dinosaur, Abydosaurus mcintoshi. The fossilized remains, found near the Carnegie Quarry in Dinosaur National Monument, provide valuable insights into the evolution of these massive creatures and their diets.
A nearly complete fossilized snake from India, Sanajeh indicus, has been discovered coiled around a sauropod dinosaur egg and a freshly hatched hatchling. The find provides critical information about the early diversification of snakes and how they evolved to eat large prey.
A study by a University of Michigan researcher found that treadmill training can help infants at risk for neuromotor delays walk on the same trajectory as normal children. The intervention reduced toe-walking in affected infants and showed a critical window for improvement between 10-18 months.
Researchers Ivette Perfecto and John Vandermeer argue that small family farms in tropical regions can provide a better way to meet both food production and biodiversity preservation goals. They propose an alternative model, the matrix quality model, which enables plants and animals to migrate between remaining forest fragments.
Researchers at the University of Michigan are exploring plug-in hybrid electric vehicles that can store electricity from the grid or generate it, making them a potential solution for storing excess energy. The team aims to understand how these vehicles can influence the reliability and stability of the electrical grid.
Researchers at the University of Michigan developed an artificial foot that recycles energy wasted in between steps, reducing energy spent per step by 14% compared to conventional prosthetic feet. This innovation could significantly improve walking efficiency for individuals with lower limb amputations.
Researchers developed a new approach to track mercury's movement through Arctic ecosystems using a 'fingerprint' method. The study confirmed mass-independent fractionation occurs during sunlight-driven reactions in snow, allowing for the estimation of mercury loss and retention.
Researchers at the University of Michigan have developed a millimeter-scale, energy-harvesting sensor system that can run for nearly perpetual periods using solar power. The system's low-power processor and innovative voltage conversion method enable it to consume less than 1 nanowatt of power on average.
Researchers at the University of Michigan have shown that small mechanical forces can control gene expression by reducing DNA looping, a common mechanism for gene regulation. The study provides new insights into how cells regulate themselves and could lead to new understandings of diseases such as cancer and cardiac disease.
A new study by researchers at the University of Michigan found that echolocating bats and whales share a similar molecular mechanism for this ability, overturning conventional thinking on convergence. The research focused on the prestin gene, which plays a crucial role in hearing and amplifying sounds.
Researchers developed a device that gently rocks embryos during in vitro fertilization (IVF), improving pregnancy rates in mice by 22%. The procedure may lead to significantly higher IVF success rates in humans, reducing the incidence of twins and triplets.
A strip of paper infused with carbon nanotubes can quickly and inexpensively detect microcystin-LR, a chemical compound produced by cyanobacteria, found in nutrient-rich waters. The biosensor works by measuring the electrical conductivity of the nanotubes in the paper, changing their conductivity when the toxin is present.
The study reveals that RNA molecules' 3D shapes are dictated by their junctions, similar to how anatomical features define arm motion. The researchers also found that drug molecules interact with RNA in predictable ways, with size being a key factor in determining the preferred orientation.
A study published in the Journal of Infectious Diseases found that each additional 1.1 pounds of birth weight decreases tuberculosis risk by 46% among identical twins. The association is stronger for males, with an 87% reduced risk, and sheds light on the developmental origins of health and disease.
Researchers Steven Skerlos and James Winebrake argue that government subsidies for plug-in hybrid electric vehicles (PHEVs) should be tailored to specific locations and consumer characteristics. They found that PHEVs are most effective in areas with low-carbon fuel production, high driving volumes, and poor air quality.
Researchers found that HdeA lets go of unfolded proteins gradually, allowing them to refold instead of clumping together. This unique mechanism allows HdeA to harness energy from the environment, making it a more efficient chaperone.
Researchers have discovered changes in the collagen component of bone that directly relate to bone health. The study uses atomic force microscopy to measure key features of collagen fibrils and found that normal bone contains a distribution of collagen fibril spacings, whereas diseased bone has a different spacing distribution.
A University of Michigan research team analyzed 47 embryonic stem cell lines and found they lacked genetic diversity, with most derived from northern and western European ancestry. The lack of diversity raises concerns about unequal access to therapies for certain groups.
A new study reveals that at least 1,250 and possibly more venomous catfish species exist, with North American species using their venom mainly to defend against predatory fish. The research also sheds light on the evolutionary origins of catfish venom glands.
Researchers at the University of Michigan have discovered a way to stabilize proteins by linking their stability to antibiotic resistance in bacteria. This method enables easy selection for stabilizing mutations, rendering proteins more resistant to unfolding and increasing their practical utility.
Scientists at the University of Michigan discovered that certain pyramid shapes can spontaneously organize into intricate quasicrystals without any external interactions. This finding could lead to the development of new materials with unique properties, such as optical properties useful for communication and stealth technologies.
A new study led by the University of Michigan reveals that polar bears get their nutrition from two main food webs: phytoplankton-based and ice algae-based. The research found that those who primarily eat phytoplankton have higher mercury concentrations, highlighting the importance of understanding Arctic ecosystems.
Researchers explored how changes in water content affect bone's structure and dynamics, revealing dynamical structural changes in collagen. The study's success enables future research into atomic-level behaviors of bone under different conditions.
Researchers discovered a new antioxidant system that shields single cysteine residues from oxidative harm, reducing cancer and heart disease risk
Researchers developed an Android app called PowerTutor to help users compare the power consumption of different applications. The app provides real-time information on how phone components use power, enabling users to make informed decisions about their device's energy efficiency.
Scientists at the University of Michigan have determined the atomic-level structure of a SEVI precursor and found it damages cell membranes to make them more vulnerable to HIV infection. The study provides insights into how SEVI interacts with cell membranes, which may help in developing new treatments for AIDS.
A new study by University of Michigan researchers found that people with less education are more likely to get H1N1 and the flu vaccine may be less effective in them. The study suggests that lower socioeconomic status can make it harder for adults of all ages to fight off new infections.
Researchers at the University of Michigan have developed hybrid molecules that can regulate copper-induced amyloid-beta aggregation, disrupting clump formation and breaking up existing clumps. The new compounds also hold promise in treating Alzheimer's disease and may be able to cross the blood-brain barrier.
A University of Michigan study found that color differences in fruit flies have a common genetic basis with those in humans and chimps. Genetic analysis revealed the tan gene as responsible for part of the color variation within and between species.
A new University of Michigan study reveals that employees with metabolic syndrome (MetS) and associated chronic disease can incur healthcare costs up to $5,867 annually. Employers can prevent these conditions by implementing health risk appraisals and prevention programs, which cost as little as $150 per year.
A University of Michigan survey found that the cost of plug-in hybrid electric vehicles (PHEVs) is a significant predictor of purchase probabilities, even more so than environmental considerations. Economic factors, such as willingness to pay for fuel savings and price premiums, played a crucial role in consumer attitudes towards PHEVs.
Researchers at the University of Michigan have found that genes involved in fin regeneration and heart repair are also required for rebuilding damaged light receptors in the eye. The study suggests that a common molecular mechanism guides the process, no matter what body part is damaged.
Researchers found that individual wasps benefit from being recognizable, as they are less likely to be targeted in aggressive encounters. This finding suggests that diversity may promote group stability, extending beyond wasp societies to potentially influence human facial variation and social interactions.