Scientists at The University of Nottingham have uncovered a vital new biological clue that could lead to more effective treatments for CNS PNETs, a type of brain tumour predominantly occurring in children. The research found that WNT pathway activation is linked to patient survival and may represent an important new target for treatment.
A three-year study funded by the MS Society is investigating whether infection with hookworms can lead to an improvement in the severity of multiple sclerosis. The trial, which involves 72 patients, aims to determine if the worms can provide a simple, cheap, natural treatment for the condition.
Scientists at the University of Nottingham and the University of California, Berkeley have provided evidence for a new kind of sudden transition between liquid and solid glass. This transformation occurs when molecules are viewed in both space and time, guiding towards methods for producing stronger and longer-lasting glass.
Researchers have recorded the earliest evidence of animal life using Hydropyrolysis technology, dating fossil steroids 635-750 million years old. This discovery suggests that simple multicellular animals existed in shallow waters before the Cambrian explosion.
Dr Catherine Jopling has received a prestigious David Phillips fellowship to investigate the molecular biology of hepatitis C virus. The £1m funding will support her work on miR-122, a specialized liver microRNA that interacts with HCV in an unusual way.
A three-year study using gene knock-out technology aims to discover why C. difficile causes severe disease and kills more people. The HYPERDIFF study will lead to better tests, treatments, and possibly a vaccine.
Researchers are sending worms to the International Space Station to study muscle atrophy in zero gravity. The goal is to understand why astronauts experience dramatic muscle loss and potentially develop new treatments for muscle wasting diseases.
A new study examines the experiences of older people with persistent pain, revealing nearly five million UK residents over 65 are affected. The report highlights ageist attitudes and emphasizes the need for improved assessment and treatment to address this issue.
A new study claims that the Integrated Children's System (ICS) is creating 'latent conditions for error' in front-line children's services, leading to potential harm to vulnerable children. The researchers argue that the system's complexity and pressure to meet deadlines are undermining good social work practice.
The study shows that many young adults in their 16-24 age group face emotional turmoil while juggling caring responsibilities with education and personal life. Personal experiences highlight the need for support and awareness to enable these young individuals to succeed.
Researchers at University of Nottingham identified the tumour suppressor gene LIMD1 as a protector against lung cancer. The study found that LIMD1 was missing in majority of lung cancer samples, indicating its protective role. This breakthrough could lead to early screening techniques and treatments for lung cancer.
Biologists have discovered a sexual cycle in the deadly fungus Aspergillus fumigatus, revealing its ability to adapt to new environments and evade antifungal drugs. This breakthrough could lead to new treatments for patients infected with the fungus, which causes severe asthma and immune deficiency-related deaths.
Researchers are exploring how drugs interact with cells to identify new ways to overcome resistance. By combining physics and mathematics, they aim to control drug delivery and reduce multidrug resistance in diseases like cancer and malaria.
A new study by the University of Nottingham found that good pre-schools followed by high-quality primary schools significantly improve children's development. A stimulating home-learning environment at age 3-4 years is also linked to long-term gains in children's development.
Researchers aim to identify undiscovered genes involved in early breast cancer stages by studying genetic information from thousands of breast samples. The technique could help monitor women at higher risk due to inherited gene defects, reducing mortality from breast cancer.
Carbon nanotubes are used to create a non-volatile memory cell with high speed and low power consumption. The new technology combines the benefits of dynamic and flash memories, overcoming fundamental limits of current memory technologies.
A study by Hayley Frend found that pond snails exhibit handedness in mating behavior, mirroring brain asymmetry pre-programmed by their mother's genes. This discovery sheds light on brain specialization and its importance across species.
Researchers at the University of Nottingham are using MRI technology to investigate whether brain abnormalities can predict drug addiction. The three-year study aims to understand why some people become addicted while others do not, with a focus on the frontal cortex and its role in decision-making.
Researchers found that women place significant importance on altruistic traits when choosing a partner. Altruistic behavior was correlated with stronger preference for such traits in both men and women.
The QResearch database has released a new report on public health indicators, including obesity, smoking, and cholesterol levels in over four million patients. The study finds that smoking rates are highest in deprived areas and that obesity levels continue to rise in the North and Wales.
A three-year research project aims to reduce CO2 emissions from UK homes by upgrading existing properties with low-carbon technologies. The E.ON 2016 House, a fully-equipped test facility, will track energy consumption and emissions data to identify effective improvements.
Researchers will examine organisational systems of 40 companies to understand how culture, leadership, policies, and change affect employee health and productivity. The study aims to improve theory and practice in managing work-related health, with potential implications for policy and national guidance in Europe.
The University of Nottingham is conducting a study to understand women's experiences working through menopause, with the goal of providing useful information for women, employers, and doctors. The research aims to address the significant gap in understanding the effects of menopause on women's working life.
A new research project will develop and test new ways of scanning childhood tumours in depth, giving doctors a more detailed diagnosis and better indication of how to treat the tumour. This project is part of a nationwide investment of £50m to establish cancer imaging centres and research programmes.
A study by the University of Nottingham aims to identify bacterial antigens that could lead to an effective vaccine against Bovine Mastitis. The researchers will use state-of-the-art molecular technology to determine which proteins are essential for infection.
Scientists at the University of Nottingham are investigating a triple cocktail of medicines to lower stroke risk in recovering patients. The study aims to determine if adding clopidogrel to aspirin and dipyridamole improves recovery outcomes.
Researchers are developing a simple blood test to diagnose Alzheimer's disease by identifying biomarkers in the blood. The study aims to provide an early and accurate diagnosis, allowing for effective treatment to be given sooner.
A new five-year research centre will be established in the East Midlands, focusing on improving patient care through innovative healthcare approaches. The Collaborative Leadership in Applied Health Research and Care (CLAHRC) will prioritize patients' needs and translate research findings into practical service improvements.
Research shows that female fallow deer are attracted to deep calls from dominant males, who also have higher mating success. The study found a link between the depth of the call and body size, suggesting size exaggeration may be an evolutionary trait.
Researchers at the University of Nottingham have created a novel technology using fluorescence correlation spectroscopy to detect and track single molecule binding to A3-adenosine receptors. This allows for real-time observation of receptor activity within living cells, shedding light on potential anti-inflammatory drug targets.
A new drug development project aims to create a modified beta-blocker that targets the heart without affecting lungs, benefiting hundreds of thousands of heart patients with respiratory conditions. The treatment has the potential to become the general medicine of choice for all heart patients due to its reduced side effects.
Researchers focus on two muscle fibre types to achieve tastier cuts of meat without sacrificing production values. The study aims to identify genes important in slow muscle growth, enabling farmers to breed naturally flavorful and succulent meat.
A new research project uses computer modeling to look at the best way of using ventilators while minimizing the risk of injury. Real-life data collected from patients will be used to create the models, which could lead to computer management of ventilators for optimal treatment and reduced harm.
A three-year study will investigate how low levels of environmental chemicals affect sheep foetuses and potentially human health. The researchers aim to understand the long-term reproductive effects of exposure to hormone-like chemicals, which could have greater consequences for females than males.
Researchers plan to reduce binge drinking by providing workplace information and employee commitments, with a focus on raising awareness of health effects. They will follow up with employees to assess long-term behavior change.
A major review found that only two per cent of paediatric drug trials had independent safety monitoring committees to detect adverse drug reactions. Clinical drug trials in children are essential for developing medicines and treatments, but greater safety measures and awareness are needed.
Researchers at the University of Nottingham discovered that Aspergillus nidulans fungi can reproduce sexually without a partner. This 'DIY reproduction' allows individuals to produce new offspring by activating internal sexual machinery, bypassing traditional mating.
A new study by researchers at the University of Nottingham found that oral antibiotic treatment can be as effective as injections in treating childhood pneumonia. The study involved 243 children and showed that oral treatment led to reduced pain, shorter hospital stays, and fewer oxygen therapy sessions.
Researchers found that children can solve large number problems without mastering place value or addition facts, using their natural sense of number to perform approximations. This talent can be built upon in the classroom to enhance interest and understanding in elementary mathematics.
A University of Nottingham scientist has won a Royal Society award for his work in developing ways to capture carbon dioxide from the atmosphere. The award recognizes the potential of this technology to play a key role in reducing global climate change and reducing the need to store highly pressurized CO2 underground.
The University of Nottingham has been awarded a £300,000 grant to collaborate with Indian researchers on a four-year project exploring mixture toxicity in living organisms. The project aims to develop a mathematical model predicting how organisms respond to chemical pollution.