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University of Oxford


Ability of brain to protect itself from damage revealed

Researchers at the University of Oxford have identified a natural biological mechanism that allows brain cells to survive during a stroke, enabling the development of potential neuroprotective drugs. The 'endogenous neuroprotection' discovered in rats has shown to increase cell survival by stimulating production of hamartin protein.

SourceUniversity of Oxford·JournalNature Medicine·DateFeb 24, 2013

Gene today, gone tomorrow: Genes for autism and schizophrenia only active in developing brains

A new study published in Proceedings of the National Academy of Sciences reveals that genes linked to autism and schizophrenia are only switched on during early stages of brain development. Researchers used advanced techniques to map gene activity in mouse brains, identifying key populations of subplate neurons and shedding light on th...

SourceUniversity of Oxford·JournalProceedings of the National Academy of Sciences·DateFeb 11, 2013

Routes towards defect-free graphene

A new technique has been developed to grow graphene without defects, enabling the creation of larger sheets with aligned flakes and improved electron flow. This breakthrough has significant implications for industrial-scale graphene manufacturing and the development of graphene-based technologies in electronics, energy, and healthcare.

SourceUniversity of Oxford·JournalACS Nano·DateFeb 1, 2013

Target 'super-spreaders' to stop hepatitis C

A new study suggests that early diagnosis and treatment of Hepatitis C in intravenous drug users can prevent many transmissions by identifying 'super-spreaders' who are highly infectious. By understanding how the virus spreads in these individuals, researchers hope to develop targeted interventions to stop its spread.

SourceUniversity of Oxford·JournalPLOS Computational Biology·DateJan 31, 2013

1000 genomes study is 'guidebook' to how genes vary

The 1000 Genomes Project has sequenced 1,092 human genomes, providing a genetic guidebook to help researchers interpret genetic changes in people with disease. The study found that rare gene variants are restricted to specific geographic regions and can be used to identify individuals at risk of certain conditions.

SourceUniversity of Oxford·JournalNature·DateOct 31, 2012

Single gene cause of insulin sensitivity may offer insight for treating diabetes

A study published in the New England Journal of Medicine reveals that mutations in the PTEN gene can improve metabolism and increase insulin sensitivity in people with Cowden syndrome. The researchers found that those with Cowden syndrome had higher levels of obesity, but the extra weight was caused by extra fat storage, not muscle mass.

SourceUniversity of Oxford·JournalNew England Journal of Medicine·DateSep 12, 2012