A clinical trial testing an Ebola vaccine developed on a new cell line is underway in Senegal, aiming to provide a rapid response to outbreaks. The trial uses two vaccines, ChAd3-EBO Z and MVA-EBO Z, which have shown excellent safety profiles and promise for low-cost mass production.
A study suggests that sleep deprivation can prevent the consolidation of traumatic memories, reducing flashbacks. Participants who slept normally experienced more intrusive memories than those who were sleep-deprived.
Researchers found that hierarchical social structures, where individuals follow a single leader with rapid information passing down the 'chain of command', enable pigeon flocks to navigate accurately. This allows for better decision-making even when individual birds make navigation errors.
Researchers analyzed thousands of women's genomes to determine how genes affect the age of first-time mothers and family size. They found that genes account for about 15% of the differences in these outcomes, suggesting an inherited reproductive advantage.
A pioneering Oxford University study using MRI scans found that babies experience pain much like adults, with 18 of 20 brain regions active in adults also active in babies. The study suggests that infants may be more sensitive to pain than adults and highlights the need for improved pain relief guidelines.
A new study by University of Oxford researchers found that excessive video game time is associated with problem behavior in children, while the type of games played has no significant impact. The study suggests that parents should monitor their child's gaming time to minimize potential risks.
Researchers analyzed DNA samples from 64 populations in Europe, Africa, and the Americas to uncover the genetic fingerprints of the slave trade and colonization. The study found that Americans have a complex genetic profile, with varying proportions of African and European ancestry.
A new study reveals that early modern humans relied heavily on the rainforest for their diet, contradicting the long-held assumption that they avoided tropical forests until around 12,000 years ago. The research analyzed teeth dating back 20,000 years and found that nearly all individuals had a diet sourced from the rainforest.
A new brain imaging study has identified a specific brain area, the dorsal posterior insula, directly related to pain intensity. This discovery could help detect pain in people with limited communication abilities.
Researchers measured growth and photosynthesis rates in Amazonian trees during severe droughts, finding a 10% decrease in photosynthesis rates. This decrease did not affect growth rates but led to increased tree deaths and potential climate change acceleration.
A study by University of Oxford researchers exposes shortcomings in the 'index-calibration' method used in tiger and rare wildlife surveys. The team found that this approach can produce inaccurate results, especially with high uncertainty in detection rates. They suggest alternative methods to improve conservation efforts.
A new study by Oxford University scientists reveals that migrating birds 'share the pain' of leading a v-formation, allowing them to take turns saving energy. The research found that individual birds spend an average of 32% of their time benefiting from flying in the updraft produced by another bird's flapping wings.
A new study found that humans carry fewer endogenous retroviruses in their genomes compared to other mammals. This decrease may be attributed to a less bloody evolutionary history, with reduced exposure to blood-borne viruses as humans transitioned from biting during conflicts and hunting.
The GSK/NIH Ebola vaccine candidate has shown a well-tolerated safety profile and generated an immune response in healthy volunteers. Larger trials are necessary to assess whether the immune responses offer protection against Ebola infection and disease.
Researchers studied the 'garden centre spider' to understand how it spins ultra-fine filaments. The spider uses electrically charged threads to create 'catching wool', which is made of thousands of nano-scale filaments that are combed out and charged.
A 415 million-year-old fish fossil suggests that humans and sharks share more primitive features than previously thought. The ancient creature, named Janusiscus, has a mix of cartilaginous and bony fish-like characteristics, which challenges the current classification of sharks as 'primitive'.
Researchers developed a blood test that detects changes in zinc isotopic composition to identify biomarkers of early breast cancer. A pilot study showed promising results, with the ability to detect key differences in zinc caused by cancer.
Researchers found that great tits learn new foraging techniques by observing others in their social network, adopting the dominant behavior and creating a stable tradition. Even when birds discover multiple methods, they tend to conform to the majority behavior, passing it down to the next generation.
Birds use collapsible wing tucks to respond to turbulent air masses, reducing lift and minimizing jolting. Researchers found that this technique could potentially be used in micro air vehicles to maintain stability in windy conditions.
A new study reconstructs the genetic history of HIV-1 group M and concludes that it originated in Kinshasa around 1920. The team's analysis suggests a 'perfect storm' of factors, including urban growth, transport links, and social changes, contributed to the emergence of HIV from Kinshasa and its spread across Africa and the world.
Researchers at Oxford University found that dry roasting peanuts causes chemical modifications that activate the immune system, leading to an allergic response. This discovery may explain the higher prevalence of peanut allergies in Western countries compared to East Asia.
The international standards provide a common set of criteria for healthy growth, allowing for early detection of underweight and overweight babies. This enables targeted nutritional support and treatment to prevent infant mortality and long-term health problems.
A new Oxford University study reveals differences between individual primate brains linked to their social status, with larger brain regions associated with dominance and subordination. The research also found that brain activity patterns vary with position in the social hierarchy.
A study found that the EU's policy on tobacco control shifted in favor of the industry following massive lobbying. The research used automated content analysis to track changes in language used by health groups and industry stakeholders, revealing a significant shift towards industry interests.
A new study by Oxford University found that young people who played video games for less than an hour a day were associated with being better adjusted than those who played more or never. They reported higher sociability and fewer friendship problems compared to heavier gamers.
A new kidney transplant drug has been shown to halve the early risk of rejection, allowing a less toxic regimen of anti-rejection drugs to be used. The study, published in The Lancet, found that alemtuzumab-based induction therapy reduced acute rejection by 69% compared to basiliximab-based induction therapy.
Researchers found that only 8.2% of human DNA has a clear function, with most being 'junk' DNA. This figure challenges the previous claim of 80% functional DNA, highlighting the need for a more precise definition of 'function'.
Physicist Dr David Robert Grimes has derived equations to explain how guitar techniques manipulate pitch, shedding light on string bending, vibrato, and whammy bars. His research provides insights into the physics behind iconic guitarists' sounds.
A study has identified over 27,000 endogenous retroviruses preserved in the genomes of 38 mammal species, including humans. Larger animals have fewer ERVs, suggesting they may have evolved mechanisms to combat cancer-causing mutations.
Researchers found that taking B vitamins had no effect on cognitive decline or reducing the risk of Alzheimer's disease in a meta-analysis of 11 clinical trials involving 22,000 participants. The study suggests that folic acid and vitamin B-12 can lower homocysteine levels, but not prevent the disease.
Researchers captured a genetic snapshot of maize 10 million years ago and traced how it used copied genes to cope with domestication pressures. These gene copies played a vital role in optimizing photosynthesis in maize leaves.
Researchers at Oxford University have developed a new discovery of nano-pixels that can be electrically switched on and off to create high-resolution images. The tiny 'nano-pixels' are just 300 nanometres in size and can be used for applications such as smart glasses, synthetic retinas, and foldable screens.
A new study reveals that users tend to be swayed by recent activity of their friends on Facebook, rather than relying on best-seller lists. The researchers developed a mathematical model to capture the dynamics at play, finding that the 'copycat' tendency plays a strong role in online behavior.
A new study published in The Lancet found that partial knee replacement surgery is safer than total knee replacement, with fewer life-threatening complications and deaths. Patients who undergo partial knee replacement are less likely to experience major complications such as heart attacks, strokes, or deep infections.
A landmark study by Oxford University researchers found that babies' bone growth in the womb and their length and head circumference at birth are strikingly similar globally when born to educated, healthy, and well-nourished mothers. The study involved almost 60,000 pregnancies across eight urban areas worldwide.
Astronomers have discovered three closely orbiting supermassive black holes in a galaxy over four billion light years away. The system's tight configuration suggests that these closely-packed black holes are far more common than previously thought.
Researchers developed a computer programme that recognizes facial features in photographs to diagnose rare genetic disorders. The algorithm improves accuracy by learning from a growing bank of photographs and identifying clusters of patients with the same condition.
Research by University of Oxford links recession to significant rise in suicides across EU, Canada, and USA between 2008-2010. The study suggests that job loss, home repossession, and debt are major risk factors leading to suicide during economic downturns.
Researchers at the University of Oxford have developed a simple and quick MRI technique that can detect people with early-stage Parkinson's disease with 85% accuracy. The new approach uses resting-state fMRI to analyze brain connectivity in the basal ganglia, identifying those who are at risk before symptoms appear.
Researchers found that spider silk can be tuned to a wide range of harmonics, allowing spiders to detect vibrations from prey and mates. This unique property could inspire new technologies such as tiny sensors.
Researchers used high-powered lasers to create table-top supernovae, recreating the explosive events that occur when stars reignite or collapse. The experiments revealed irregular 'knotty' features and intense radio and X-ray emissions, confirming a theory about the interaction between magnetic fields and interstellar material.
Research by Oxford University psychiatrists found that serious mental illnesses can cut life expectancy by 10-20 years, comparable to the risks associated with heavy smoking. The study emphasizes the need for governments and healthcare systems to address mental health disparities and provide accessible services.
In a study published in Science, researchers found that fruit flies accumulate information before making decisions, suggesting a level of intelligence. The study identified a key gene, FoxP, involved in this process, which may also be linked to human cognitive development and language abilities.
A team of scientists has identified cancer stem cells in patients with myelodysplastic syndromes, a malignant blood condition that frequently develops into acute myeloid leukemia. The study provides conclusive evidence for the existence of cancer stem cells and suggests that targeting these cells could lead to effective treatment.
A study found that dinosaurs showed rapid rates of body size evolution in early forms, but these slowed down over time. However, the evolutionary line leading to birds continued to change size at this rate for 170 million years, producing new ecological diversity not seen in other dinosaurs.
Researchers at Oxford Health NHS Foundation Trust and the University of Oxford conducted a UK study on the use of ketamine intravenous infusions in people with treatment-resistant depression. The study found that 29% of patients experienced benefit that lasted at least three weeks, while 15% took over 2 months to relapse.
Researchers created 3D X-ray movies of a blowfly's flight muscles, showcasing their complex movements and control. The study provides new insights into how flies manage to perform aerobatic maneuvers with precision, opening up possibilities for innovation in micro air vehicles.
A review of 64 randomized controlled trials found no consistent evidence that home care visits improve the lives of elderly individuals. The studies, conducted over the last 20 years, involved nearly 29,000 people aged over 65 and examined various outcomes such as mortality rates, falls, hospitalization, and quality of life.
A randomized controlled trial by the University of Oxford found that higher levels of omega-3 DHA in the diet are associated with better sleep in healthy children. The study, which involved 362 children aged 7-9, showed that supplements improved sleep duration and reduced waking episodes.
Researchers at University of Oxford are using patient stories to stimulate change in healthcare. They've found that small changes, such as clocks on the wall for intensive care patients or more comfortable pillows, can greatly improve patient experience. This approach brings compassion and dignity back to the fore.