Researchers discovered a correlation between rare POLE mutations in bowel cancers and improved patient outcomes. These tumours are less likely to recur, particularly when diagnosed at an early stage.
Researchers suggest combining genetics and cognitive bias studies to better understand mental health, finding that shared genes can make individuals prone to both positivity and negativity.
New research reveals that newborn ducklings can learn to identify and follow abstract relational concepts, such as 'same' and 'different', without reinforcement training. This ability was previously known only in highly intelligent animals like apes and parrots.
Researchers at the University of Oxford have made breakthrough in treating HIV by targeting its dormant cells. A novel protein called ImmTAV has been shown to effectively kill latently infected cells in laboratory conditions.
Researchers used genetic sequencing to track gonorrhea infections across borders, revealing that 3/4 of cases in Brighton could be linked to earlier local cases. The study also found evidence of gonorrhoea spreading to and from Brighton from the rest of the UK and the US.
Researchers found that Brazilian capuchins used stones as hand-held hammers and anvils to pound open hard foods, creating recognizable cashew processing sites. The tools were made from smooth, hard quartzite stones and dark-colored residues confirmed the use of cashew nuts.
Researchers from Oxford University used computer simulations to demonstrate how chaotic bacterial swarming can be organized to power microscopic rotors and devices. The study found that densely packed bacteria can spontaneously assemble into a 'bacterial windfarm' capable of generating persistent mechanical power.
A study published by the University of Oxford found that man-made climate change was responsible for hundreds of deaths in two European cities during a 2003 heatwave. The research used computer simulations and health impact assessments to estimate the number of premature deaths attributed to climate change.
In a groundbreaking study, pea plants were found to make choices that take into account environmental variance, similar to animal behavior. The plants grew more roots in pots with variable nutrient levels when conditions were poor and more roots in constant pots when conditions were good.
A study published in Psychological Medicine identified risk factors that can predict post-traumatic stress disorder (PTSD) and major depression among emergency services workers. Early assessment can help offer targeted training to improve resilience, reducing episodes of mental illness and improving long-term health.
A team of researchers at Oxford University has identified four genes that play a crucial role in early human development. These genes, known as Argfx, Leutx, Dprx and Tprx, are activated for an extremely brief period, when the embryo is a tiny ball of 8-16 cells. They then switch off, controlling the 'first gear' of embryonic growth.
A new exploration technique has discovered significant helium reserves in Tanzania, providing a much-needed supply to address the growing demand. The discovery could fill over 1.2 million medical MRI scanners, alleviating a critical shortage of this vital element.
Researchers found MAIT cells can bypass specific receptors to react to cytokine combinations, previously only known for fighting bacteria. The discovery suggests MAIT cells could be involved in defending against or reducing the effects of viruses.
A study published in Pediatrics found that exclusive breastfeeding improved heart volume and function in premature babies, with those consuming more breastmilk having better outcomes as adults. The research suggests that breastfeeding may be able to mitigate the negative effects of premature birth on cardiac development.
A study by Oxford researchers found that exposure to green light rapidly induces sleep, whereas blue and violet lights delay sleep. The role of melanopsin, a pigment regulating the body clock, was confirmed as essential for these effects.
Researchers found that archerfish can distinguish between up to 44 new faces, demonstrating impressive visual recognition capabilities. The study suggests that simple brains may be capable of complex tasks like facial recognition.
A new study reveals that human activity has shaped the world's landscapes for thousands of years, leading to significant extinctions and ecosystem changes. The research highlights four major phases of human impact, including global expansion, agriculture, island colonization, and urbanization.
Oxford University researchers found that infants' cuteness appeals to all senses, triggering caregiving behaviors vital for infant survival. This study reveals the complex choreography of slow, deliberate prosocial behaviors eliciting fundamental brain pleasure systems.
Researchers at Oxford University have identified the oldest known population of plant root stem cells, preserved in a 320 million-year-old fossil. These ancient stem cells provide unique insights into the evolution of roots and their role in shaping the Earth's climate.
A new paper proposes that dogs were domesticated independently from two distinct wolf populations on opposite sides of the Eurasian continent. Genetic analysis reveals a genetic separation between modern dog populations in East Asia and Europe.
Researchers identified the mediodorsal thalamus as a key brain area involved in rapid information processing and decision-making. The study found that monkeys with lesions to this area struggled to adapt their behavior and make informed choices.
Researchers identified Asian crop remains in Madagascar, providing archaeological evidence of Southeast Asian colonization over 1,000 years ago. Genetic research confirms the connection between Malagasy speakers and Austronesian language families.
Researchers at University of Oxford have identified two long intergenic noncoding RNA genes associated with an increased likelihood of developing bacteraemia when infected with Streptococcus pneumoniae. The genetic variants carry a doubled risk, highlighting the importance of diverse population studies.
A new phenomenon dubbed 'red geysers' has been identified in galaxies, which host low-energy supermassive black holes driving intense interstellar winds. These winds prevent gas from cooling and condensing into stars, maintaining quiescence in galaxies.
Researchers found that taking aspirin immediately after a minor 'warning' event significantly reduced the risk of major stroke over the next few days. The study showed that aspirin also reduced the severity of early strokes by about 70-80%.
Researchers discovered a unique 'hybrid' material in spider webs that maintains tautness even under stress. By mimicking this process, they created composite fibres with solid and liquid properties.
New research from the University of Oxford used bacteria to show that acquiring duplicate copies of genes can provide a template for developing new traits. Gene duplication has been proposed as playing a key role in innovation since the 1970s, but these findings add important empirical evidence to support this theory.
A study from Kings College London and Oxford University found that training in concrete processing can reduce PTSD symptoms by altering the way people think about traumatic memories. Concrete processing involves focusing on how a situation is unfolding, whereas abstract processing involves analyzing why something is happening.
The study found that venomous and endangered species, as well as those with higher body mass or posing a threat to humans, tend to be more interesting overall. The top 10 reptiles accessed on Wikipedia in 2014 were dominated by fearsome species like the Komodo dragon, saltwater crocodile, and king cobra.
Researchers estimate cheetah populations in the Maasai Mara to be lower than previously thought, with an average of 1.28 adult cheetahs per 100km2. The 'spatially explicit' method used can distinguish between visiting and resident animals, providing a more accurate count.
Research at University of Oxford found that individuals with more friends have a higher pain tolerance due to increased endorphin release, which promotes social bonding and pleasure. Additionally, the study discovered correlations between fitter people, those with higher stress levels, and smaller social networks.
A pioneering gene therapy has restored vision to patients with a rare form of genetic blindness for up to four years, providing sustained improvement and raising hopes for a cure. The treatment involves injecting a virus into the eye to deliver billions of healthy genes, replacing a key missing gene.
A meta-analysis of nine randomized trials found that Mindfulness-Based Cognitive Therapy (MBCT) is an effective treatment option for preventing major depression relapse. Participants who received MBCT had a 31% lower risk of relapse compared to those who did not receive the therapy.
Research from the University of Oxford found that schools with higher proportions of female students and university-educated parents have more eating disorders among their students. Eating disorders affect 5.7% of adolescent girls in Sweden, with serious consequences including early death.
The study found that a lack of adequate mentors and role models for women is a significant deterrent to pursuing a career in medical research. Additionally, women who were exposed to medical research during their training were more likely to pursue a research career.
A clinical trial of the experimental Ebola drug TKM-130803 has shown that it does not improve survival in adults with severe Ebola infection. Despite this, the study suggests that the drug may have a benefit for patients with less severe disease.
A new study by researchers at the University of Oxford and the University of Toronto has found that upgrading roads and joining them to the city grid can dramatically increase land and property prices, leading to improved financial security for poor households. This infrastructure project in the Mexican city of Acayucan resulted in a 7...
The £43m study will create the biggest collection of scans of internal organs, transforming the way scientists study diseases like dementia, arthritis, cancer, heart attacks, and strokes. This will give new perspectives on preventing and treating multi-faceted conditions.
Scientists at Oxford University have identified biomarkers that could indicate TB risk and provide clues to assess the effectiveness of potential new vaccines. The discovery was made using immune correlates, also known as biomarkers, which can be measured in the blood.
New research from Oxford and Cornell Universities reveals that people's moral judgments are based on absolute rules, even when given more time. Those who adhere to these moral absolutes are seen as more trustworthy and valued in social situations, suggesting an evolutionary basis for this preference.
A 7-year study of half a million Chinese adults found that eating fresh fruit daily was associated with reduced cardiovascular mortality, with strong associations seen in both men and women. The findings suggest that widespread consumption of fresh fruit could prevent hundreds of thousands of cardiovascular deaths annually.
Researchers analyzed the genetic makeup of Zika viruses in Brazil, finding a single introduction date of May-December 2013. The study suggests a correlation between Zika virus and microcephaly cases, but more research is needed to establish causation.
Researchers propose using 'sticky molecules' like IgA to target good bacteria in the gut, preventing pathogenic species from taking hold. This approach has the potential to reduce inflammation and prevent diseases such as Crohn's and ulcerative colitis.
Researchers aim to collect and analyze 100,000 TB samples to create a database of MDR-TB genes, enabling faster diagnosis using whole genome sequencing. The project, CRyPTIC, will take around five years to complete and could potentially save lives by providing the right treatment.
A new prediction model uses three separate readings and basic patient characteristics to provide an adjusted blood pressure reading with high accuracy. The model correctly classified 93% of cases, outperforming existing guidelines in identifying hypertension.
Researchers at Oxford University found that transcranial direct current stimulation (tDCS) significantly improved motor skills in stroke patients. The study showed that tDCS reinforced training, leading to greater recovery and increased brain activity in relevant areas.
A study published in Annals of Internal Medicine found that quitting smoking abruptly is more likely to lead to long-term success than gradual reduction. After assessing 697 smokers for four weeks and six months, the research revealed a 25% higher quit rate for those who stopped all at once.
Researchers are testing SPI-1005, an oral drug containing ebselen, as a potential treatment for bipolar disorder. The treatment has shown promise in addressing the lack of effective options for patients with this condition.
New research reveals that ichthyosaurs, highly diverse during their reign, were negatively affected by global changes leading to their extinction. A two-phase event suppressed ecological diversity and wiped out the group at the beginning of the Late Cretaceous period.
A new clinical trial has begun at Oxford and Sheffield to test a potential vaccine for prostate cancer. The vaccine aims to stimulate the immune system's attack on cancer cells by recognizing a specific protein found on their surface. If successful, future studies will assess its effectiveness in preventing disease progression.