Research finds antipsychotics used inappropriately among home-bound patients with Alzheimer's disease, leading to poorer patient outcomes. Commonly used antipsychotic quetiapine is often prescribed based on behavioral symptoms and limited daily activities.
Scientists introduce a novel approach to recover lithium from used LIBs by using aprotic organic solutions to avoid hydrogen gas production and simplify the process. The new method is efficient, inexpensive, and reduces waste, making it an attractive option for sustainable recycling of lithium-ion batteries.
A new artificial olfactory system, integrated on a single chip, detects food spoilage by identifying low levels of hydrogen sulfide and ammonia gases. The system tracks freshness scores in real-time during the spoilage process.
A team of researchers has discovered a particularly efficient molecular structure for solar energy storage materials, which could lead to more efficient solar energy harvesting. The new molecules were identified by screening over 400,000 molecules with the help of machine learning and quantum computing.
A recent analysis of published studies reveals a lack of evidence to determine the dosing, safety, and efficacy of medical marijuana or cannabis-containing products for managing symptoms experienced by children with cancer. The study found that cannabinoids performed better in managing nausea and vomiting, but data are lacking on their...
Most research focuses on treating existing mental health conditions rather than preventing them or promoting mental health. Depression and anxiety disorders are frequently researched outcomes. The findings reveal a lack of evidence-based interventions for child and adolescent mental health in low-resource settings.
New research published in Human Brain Mapping indicates that deafness does not affect the mechanisms and brain circuits supporting social skills. Deaf individuals show greater activation in regions involved in processing visual inputs like signs and lip reading.
A recent study found that cast immobilization is as effective as surgery in treating older adults with arm fractures. After one year, no statistically significant differences were found between the groups in terms of disability or range of motion. The study included 276 patients aged 70–89 years who suffered a distal radius fracture.
Researchers analyzed data from 31 studies and found that cattle face a higher risk of getting tuberculosis from wildlife through indirect interactions. Indirect interaction rates were 154 times higher than direct interaction rates.
The study found that racial and ethnic disparities in cardiometabolic diseases persisted despite social risk factors adjustments. Individuals with a more favorable social risk factor profile had lower rates of lifestyle risk factors and cardiometabolic diseases.
A large study found catheter ablation reduces dementia risk by 48% and death from any cause in patients with atrial fibrillation, regardless of age, sex, or health conditions. The procedure is an important consideration for treatment options.
Researchers developed a new strategy for T-cell-based immunotherapy using aptamers, which directly activates immune cells against cancer cells without genetic modifications. The innovative regulatory circuit establishes an artificial interaction between T cells and cancer cells.
Researchers have developed a molecular 'singlet oxygen battery' that can target and kill methicillin-resistant Staphylococcus aureus (MRSA) bacteria in deep tissue layers. The technology, which does not require external light or oxygen, is highly effective in treating pulmonary infections caused by MRSA.
Researchers found that bacteria with electrically conductive protein threads can corrode iron anaerobically, producing magnetite that facilitates further corrosion. The discovery has significant implications for corrosion protection and suggests taking material properties into consideration.
A study in Cancer Medicine reveals that access to assisted suicide does not decrease conventional suicide among patients with cancer. In fact, the percentage of cancer-associated deaths by assisted suicide increased over time, while conventional cancer-related suicides showed a downward trend.
A new tool called PRESTO identifies patients with psoriasis at high risk of developing psoriatic arthritis. The tool uses a mathematical model to estimate a patient's risk based on factors such as age, sex, family history, and disease severity.
Researchers have identified a protein called Hmga1 that may help prevent bone loss associated with postmenopausal osteoporosis. Increasing the expression of this protein in rats partially reversed bone loss in ovariectomized animals, suggesting its potential as a therapeutic target.
Researchers identified a mutation in the TMCO3 gene in two sisters with short stature, and found it regulates expression of proteins controlling bone growth. A mouse model lacking the gene confirmed its role in longitudinal growth.
A meta-analysis of multiple studies found no association between depression and anxiety and most types of cancer. However, the study found a link between depression and anxiety with a 6% higher risk of developing lung cancer and smoking-related cancers.
A new method called Degradation Upcycling (Deg-Up) recovers aromatic chemicals from polystyrene waste in a two-step process. This approach produces valuable chemicals for the cosmetics and pharmaceutical industries, offering a circular plastics economy solution.
A German research team has successfully developed a novel NMR technique to quantify acute-phase proteins in human serum, which can serve as markers for inflammatory diseases. The study found significant changes in specific acute-phase proteins in patients with COVID-19 or cardiogenic shock, and offers a diagnostic potential.
A study of 29 clinical trials found that MRg-A-SBRT significantly reduces urinary and bowel side effects in prostate cancer patients, with a 44% reduction in urinary and 60% reduction in bowel side effects. This technique uses imaging technology to accurately aim radiation beams at the prostate while avoiding nearby tissue.
A recent analysis of published and unpublished studies found that Functional Family Therapy is not consistently more or less effective than other treatments, including individual, family, and group interventions. The available evidence also raises concerns about the quality of the therapy's evidence base.
Children of parents with work-limiting disabilities experience less upward and more downward economic mobility compared to their peers. However, earlier access to disability insurance benefits may mitigate these disadvantages, as seen in a study of over 52,500 parent-child pairs in the US.
A randomized controlled trial found that Nurse-Family Partnership improved child language and mental health at age 2, with no increase in child injuries or maternal pregnancies. The study involved 739 participants and their children for 2.5 years, providing new evidence on preventing early adverse childhood experiences.
A study of 2,226 US participants found significant racial differences in post-retirement cognitive decline. White men experienced the most pronounced decline, whereas Black women showed minimal loss. College attendance was linked to greater cognitive decline after retirement.
Researchers developed nanoparticles that mimic the glycocalyx pattern to treat inflammatory bowel disease. The treatment reduced symptoms and inflammation in mice with IBD, with specific versions showing significant improvement.
A team of researchers has developed a new LED technology that can detect spoiled food by emitting light in two different wavelength ranges. The modified LEDs use perovskite materials to capture and convert light, allowing for non-invasive imaging of food freshness.
Researchers found a solid deposited from ammonia and methane plasma can catalyze reactions to produce early biomolecules, such as imines, using sunlight. Nitrogen-doped graphite was used as the catalyst in these reactions.
A new study reveals Indigenous men in Canada are more likely to be diagnosed with advanced prostate cancer and experience cancer spread, despite universal healthcare access. Researchers identify key infrastructure changes needed to improve screening and treatment outcomes.
Researchers have developed a hybrid battery system that stores electricity and produces valuable chemicals, such as furfuryl alcohol and furoic acid. The new battery increases the cost efficiency of the battery system, making it a step towards improving the sustainability and cost-effectiveness of rechargeable batteries.
Researchers analyzed data on 34,789 endometrial cancer cases from Florida and the French Caribbean, finding that Caribbean Black women had the lowest rates for both subtypes. Non-endometrioid types were most common among US Black women, with rates increasing yearly for all groups.
Research suggests that bamboo can be converted into bioethanol and biogas, offering an attractive alternative to fossil fuels. The chemical composition of bamboo varies across species, highlighting the need for further research on selecting optimal species for biomass production processes.
A study published in Brain and Behavior found that humor therapy reduced symptoms of depression and anxiety in participants from various countries. The analysis included 2,964 participants and nine different countries, suggesting that humor therapy may be a feasible complementary alternative for clinicians, nurses, and patients.
Higher testosterone levels during adolescence enhance emotion control, but decrease in young adulthood; the study suggests a shift in testosterone's role across developmental periods. The findings may be related to mood disorders that arise during adolescence.
New research suggests optogenetics could restore regular heart rhythm without shocks, improving prognosis and quality of life for AF patients. Light therapy has shown promising results in rats, indicating potential translatability to humans.
Researchers have developed a new approach to treating tumors using 'self-immolative' polyferrocenes that trigger a fatal cycle of oxidative stress in cancer cells. In experiments, these copolymers inhibited tumor growth with negligible side effects, offering potential for chemodynamic therapy.
A review highlights the importance of supporting breastfeeding in India, where one-quarter of the world's children are born. The authors express concern that excessive concern about infant allergies may be undermining mother-infant bonding, breastfeeding, and child nutrition.
Inadequate household water can cause a range of adverse effects on children's health, including the spread of disease, interruptions to growth and development, and school absenteeism. This highlights the need for inclusive policies addressing water poverty and its impact on child well-being.
Researchers at Cornell University have developed a novel strategy for making recyclable polyolefins by introducing masked double bonds, known as 'Trojan horse' functional groups. These polymers can be chemically deconstructed and re-polymerized without losing quality.
Researchers have developed a sonodynamic cancer immunotherapy based on semiconducting polymer nanoparticles that can be activated by ultrasound, effectively treating orthotopic pancreatic cancer in mouse models. The treatment induces immunogenic cell death and kills cancer cells without causing excessive immune responses.
Researchers found that coronaviruses, like SARS-CoV-2, bind to individual monomeric ACE2 receptors on host cells, rather than forming dimers or oligomers. This interaction is sufficient for infection and contributes to the virus's high infectiousness.
A recent study published in the journal CANCER found that supplemental ultrasound screening can detect breast cancers missed by mammography, but it requires careful targeting of high-risk groups. Women with dense breasts are at higher risk of interval invasive breast cancer, and clinicians should consider other breast cancer risk facto...
A study published in the Journal of the American Geriatrics Society found that a 5-year increase in muscle fat stored in the thigh muscle is associated with faster cognitive decline. The research suggests that muscle adiposity plays a unique role in cognitive decline, distinct from other types of fat or muscle characteristics.
A new study found an association between lower extremity spasticity and cryptorchidism treatment in boys with cerebral palsy. Boys with more severe spasticity were especially likely to have had the surgery, suggesting a potential link between affected muscles and testicle development.
A new study found that combining conventional speech therapy with singing can improve voice problems in individuals with Parkinson's disease. The tele-rehabilitation program showed significant improvements in voice intensity and Voice Handicap Index scores, suggesting a more effective treatment approach.
Daily evening recovery may improve employees' wakefulness and calmness at work, but these benefits subside during the workday. Higher quality recovery on evenings has been linked to better sleep quality, which in turn contributes to improved mood.
A team of researchers found that a hydrogen sulfide donor adjuvant can disrupt mitochondrial respiration, suppressing heat shock protein production and making tumor cells more sensitive to photothermal therapy. This approach led to the eradication of tumors in laboratory mice with breast tumors within just a few days.
A team of researchers used 3D-electron diffraction/micro-crystal diffraction to determine the structure of Levocetirizine dihydrochloride, an over-the-counter oral antihistamine. This breakthrough allows for a better understanding of its properties and potential applications.
A recent study analyzing US FDA PATH data found a correlation between current tobacco use and symptom burden among adult cancer survivors. However, symptoms were not related to the desire to quit smoking. The findings suggest that better management of cancer symptoms may help survivors quit smoking.