A study of breast cancer patients in North Carolina found that Black patients experienced longer treatment delays than non-Black patients, with those living in higher-risk regions facing twice the risk. The researchers suggest that healthcare system structure, rather than patient characteristics, may be to blame for these delays.
A new study suggests that acupressure before surgery can reduce anxiety, while acupuncture during surgery may provide additional relief from severe pain. The research found that patients who received these treatments had better recovery scores and lower levels of pain and anxiety compared to those who received standard care.
Researchers have created a supercapacitor that combines high power and energy density using a 'breathing' electrode with chlorine gas. The new device achieves rapid charge separation and mass transfer, increasing its energy storage capacity.
A new method for rapid and specific antibody detection has been introduced, using programmable gene circuits, cell-free transcription, and electrochemical detection. The system can detect antibodies in complex samples such as blood serum and is adaptable for a wide variety of other antibodies.
Researchers have created a strong and recyclable biodegradable polyester that breaks down fully to its starting materials using mild chemical or biological processes. The new material has similar crystallinity to high-density polyethylene and retains beneficial mechanical properties.
A recent study found that pregnant Black women who felt upset by racism in the 12 months prior to delivery had significantly higher odds of depression. The study, which analyzed survey questions from 7,328 women, also highlighted the importance of respectful maternity care.
Scientists created Cyborg Cells by combining synthetic polymer networks with bacterial cells, giving them enhanced stress resistance and ability to invade cancer cells. This breakthrough demonstrates the therapeutic potential of Cyborg Cells for various applications.
A phase 2 clinical trial using boiled peanuts followed by roasted peanuts showed promising results in desensitizing 80% of children with peanut allergies. Treatment-related adverse events were reported in 61% participants.
Researchers have developed a system using microvesicles from algae that promote skin cell proliferation and migration, leading to increased collagen synthesis. The findings show promising results for the treatment of wounds and skin regeneration.
Research published in Journal of the American Geriatrics Society indicates social isolation is common among older U.S. adults and increases their likelihood of developing dementia. Nearly one-quarter of participants were socially isolated, and being isolated was associated with a 28% higher risk of dementia over 9 years.
Researchers found that combination therapy of buprenorphine and naloxone was as safe as buprenorphine alone during pregnancy, with similar outcomes in maternal health and newborn health. Larger studies are needed to confirm these findings.
A freely available measure of autism symptoms can help screen for autism and monitor changes over time in symptoms. The Autism Symptom Dimension Questionnaire (ASDQ) was applied to 1,467 children and adolescents, including 104 with autism spectrum disorder, and found to be reliable and valid.
A study found that residents living near occupied areas during the Occupy Central Movement in Hong Kong became more liberal and supportive of pro-democracy camps, with the phenomenon lasting long after the protest. The researchers attribute this to the 'on-site' effect, which increases sympathy for protesters.
Research published in Developmental Medicine & Child Neurology reveals a link between maternal diabetes and neurodevelopmental disorders such as autism, ADHD, and intellectual disability in children. Type 1 and type 2 diabetes were associated with increased risks of these conditions, while gestational diabetes was linked to autism spec...
A systematic review and network meta-analysis found that acupressure has a greater effect on reducing sleep disturbance in patients with cancer. The study suggests that nurses should be trained in acupressure to help patients experiencing sleep problems. The analysis included 24 randomized controlled trials involving 2,002 patients.
Bicycle-related injuries in the US decreased over time, with an increasing rate of injuries among older patients, particularly head injuries and fractures. Helmet wearing is crucial regardless of age to prevent such injuries.
New research reveals that California nursing homes exposed to wildfire risks have poorer compliance with emergency preparedness standards. The study found that 83.9% of these facilities had at least one deficiency compared to 76.9% of unexposed ones.
A new recycling process has been developed to convert Nylon-6 into ε-Caprolactam with over 95% selectivity and 90% yield, eliminating the need for solvents or toxic chemicals. This breakthrough offers a promising solution for managing plastic waste.
A recent study found that many young cancer survivors decline HPV vaccination due to concerns about safety, importance, and timing. The research aims to address these concerns and provide health care providers with messaging tools to encourage survivors to receive the vaccine.
A team of researchers from Lithuania has developed organic dyes showing a particularly long afterglow after being excited by light. The new material exhibits persistent thermally activated delayed fluorescence and long phosphorescence at room temperature, enabling color-tunable room-temperature organic afterglow.
A team of researchers has discovered that reactive boron compounds can efficiently target and activate molecular nitrogen, converting it to ammonium chloride at room temperature without metals or hydrogen gas. This radical-based approach opens up possibilities for ammonia production without fossil-based raw materials.
Researchers genetically engineered a microbial community that can convert CO2 into sugar and produce useful chemicals, effectively acting as a living carbon sink. The community, consisting of bacteria and cyanobacteria, produces chemicals with a negative carbon balance.
Researchers have identified three new genes, SHMT1, FAM120B, and ICA1L, and their expressed proteins that may be involved in the development of multiple sclerosis. The study provides new insights into the mechanisms underlying the disease and prioritizes promising targets for future therapy research.
Researchers developed magnetic microrobots that can bind and isolate S. aureus from milk, improving dairy safety. The 'MagRobots' use antibodies to target the bacteria, allowing for efficient pathogen isolation while preserving naturally occurring microbes.
A recent systematic review found that inclusion neither increases nor decreases learning and psychosocial adjustment in children with multiple disabilities. Individual assessments are crucial to determine each child's specific needs. The study highlights the importance of personalized approaches to support children with special needs.
Persistent pain was common among US adults aged 65+, with declines in physical function (64% persistent pain, 59% intermittent) and well-being (48% persistent pain, 45% intermittent). Cognitive decline was not significantly affected. The study highlights the importance of access to effective treatment for persistent pain in older adults.
Researchers found that low irisin blood levels could represent an early prognostic marker of muscle atrophy in microgravity environments. The study also suggested that irisin may help prevent the onset of atrophy and aging of skeletal muscle during bed rest.
New research reveals that reducing racial wage gaps would boost overall income by up to 4%. Closing these gaps would alleviate skill misallocation, unemployment, and improve labor market efficiency. The study aims to highlight the economic benefits of addressing inequality in the workplace.
A recent study identified several characteristics associated with a higher likelihood of post COVID-19 condition diagnosis. These include female sex, previous mental health disorders, and asthma. The study also found that use of outpatient care was substantially elevated among individuals with post COVID-19 condition.
The Cochrane review analyzed data from 41 randomized controlled trials of 12 different COVID-19 vaccines, involving 433,838 people worldwide. The review found that most vaccines reduced the risk of COVID-19 infection and severe disease, with few reported side effects.
Research highlights importance of long-term screening and healthy lifestyle behaviors in reducing cardiovascular disease risk among young cancer survivors. Factors such as sociodemographic status, income, education, smoking status, and physical activity levels are associated with increased or decreased CVD risk.
Researchers have developed a chemical-biological method to upcycle polyethylene waste into valuable and complex compounds of pharmacological interest. Genetically engineered fungi convert carboxylic diacids derived from PE waste into natural products, including asperbenzaldehyde, citreoviridin, and mutilin.
A team of researchers has developed a bioorthogonal molecular system that selectively transports nitrite ions to the endoplasmic reticulum, where they are released, triggering cell death in cancer cells. The system demonstrates synergistic effects with various cancer therapy drugs.
A recent study found metabolic perturbations in young nonhuman primates' liver and skeletal muscle after maternal obesity during pregnancy, even after a normal diet was introduced post-weaning. The study identified 58 altered metabolites in the liver and 46 in skeletal muscle, suggesting long-term health consequences.
A team of researchers has discovered that a reaction sequence from the reverse Krebs cycle can take place without enzymes under metal or meteorite catalysis. The study suggests that simple organic molecules existed on early Earth, even before life as we know it developed.
Nucleic acid therapies aim to treat genetic disorders and diseases, but delivering therapeutics is a significant challenge. Researchers are investigating nanoparticle delivery systems to target specific cells and sub-cellular compartments for effective delivery.
Men with metabolic syndrome had nearly four-fold higher risk of developing gout compared to those without MetS. Recovery from MetS reduced incident gout risk by nearly half.
Black patients were more likely to experience cognitive impairments, mobility issues, and vision problems after a heart attack. Functional impairments disproportionately affected Black patients and were associated with higher mortality rates.
Early application of skin moisturizers is an effective strategy for preventing atopic dermatitis (AD) in high-risk infants. A systematic review and network meta-analysis found that three types of emollients, including cream, emulsion, and mixed types, are comparable in preventing AD; however, emollient emulsion may be the optimal option.
A systematic review and meta-analysis of ADC clinical trials found that 91.2% of patients experienced treatment-related adverse events, with serious side effects including neutropenia, hypoesthesia, and thrombocytopenia. The study highlights the need for clinicians to address these toxicities in ADCs' use.
Researchers used native top-down mass spectroscopy to study the interplay between glycans and oligomerization in various therapeutic hormones and cytokines. They found that glycans significantly stabilize some proteins, such as tumor necrosis factor-α, while others, like interferon-β, are independent of glycosylation status.
Researchers report positive results from the first placebo-controlled trial of anifrolumab, a human monoclonal antibody targeting type I interferon receptor in patients with lupus. Treatment with anifrolumab was well-tolerated and sustained reduction in lupus disease activity.
A phase 2 clinical trial has generated promising results for deucravacitinib, an oral inhibitor of tyrosine kinase 2 (TYK2), in patients with active lupus. The study found that patients treated with deucravacitinib experienced significant improvements in disease activity, with response rates ranging from 34% to 58% compared to placebo.
A recent clinical trial shows that genicular nerve blocks provide short-term pain relief for patients with knee osteoarthritis. Patients who received the blocks reported significant improvement in pain scores, particularly at weeks 2 and 4.
Researchers have introduced novel ZnSe/ZnS quantum dots that efficiently drive challenging organic transformations with low toxicity. The secret to their success lies in their core/shell structure and variable coatings that can store light energy.
A recent study found that exposure to fine particulate matter during pregnancy is associated with delays in children's gross motor, fine motor, and personal-social development. The study of 17,683 infants in Taiwan suggests that protection from air pollution should start during pregnancy.
Climate change poses a significant threat to southwestern US reptile and amphibian populations, with limited-dispersal species facing the greatest vulnerability. The study suggests that prioritizing conservation efforts for these species may be crucial to mitigating habitat loss.
Urban-living Indigenous children and young people in high-income countries are disproportionately affected by atopic dermatitis and bacterial skin infections, which can lead to serious complications. This systematic review highlights the need for co-designed research with Indigenous communities to address these health inequities.
A study published in the Journal of the American Geriatrics Society found that antiepileptic prescribing to US nursing home residents with Alzheimer's Disease and dementia increased between 2015 and 2019. In contrast, antipsychotic and opioid prescribing rates declined during this period
A study found that top YouTube and TikTok videos on prostate cancer screening recommendations have low to moderate quality consumer health information. Black and Hispanic representation was underrepresented in most videos, and high-risk racial groups were not discussed adequately.