A new study assesses the environmental safety of three topical antiseptic compounds, finding high margins of safety for two of them. Researchers conclude that these substances are unlikely to cause ecological harm, providing a sound basis for interpreting future environmental data.
A new study found that racial resentment significantly motivates Americans to express confidence in misinformed beliefs about policy issues associated with race, such as human-caused climate change and COVID-19 origins. In contrast, this effect was not observed for less racially charged topics like childhood vaccine safety.
The risk of death from infective endocarditis (IE) among young US residents aged 15-44 years has doubled in the last two decades. IE cases among younger patients and those who inject drugs have increased, with mortality rates increasing by 50%.
A study published in the American Journal of Agricultural Economics estimates that access to food pantries provides a value of $600-$1,000 per client household annually. The collective value of food pantry access among pantry client households may be between $19 billion and $28 billion dollars annually.
Researchers have discovered a synthetic sulfide mineral that converts heat into electricity efficiently and safely. The novel material, composed of copper, manganese, germanium, and sulfur, shows two crystal structures within the same material and has a stable temperature range up to 400 degrees Celsius.
SourceWiley·JournalAngewandte Chemie International Edition·TypeExperimental study·DateNov 8, 2022
A study has identified a subset of early-stage melanoma patients with almost no risk of death, potentially contributing to overdiagnosis. The researchers used cancer registry data and developed models to identify patients with a very low risk of mortality.
A phase II clinical trial has demonstrated the effectiveness of nivolumab, an immune checkpoint inhibitor, in treating advanced cutaneous squamous cell carcinoma. The study found a significant response rate of 58.3% among patients who received nivolumab, supporting its use as a standard therapy for this disease.
The COVID-19 pandemic has led to a significant shift in Americans' opinions toward government and markets, with increased support for bigger government and redistribution. Despite this, the authors found no evidence that this shift will lead to specific policies or government functions.
A new system has been developed to deliver ultrasound stimulation to the brain in awake, naturally behaving mice, allowing researchers to evaluate its effects on sleep and working memory. This advance will help scientists test different ultrasound treatment protocols in mouse models of diverse neurological conditions.
A recent analysis found that higher BMI in adolescent men is strongly associated with developing early atrial fibrillation, as well as subsequent worse clinical outcomes after diagnosis. Men with higher BMIs had significantly increased risks of mortality, heart failure, and ischemic stroke.
A recent analysis found that individuals at risk for rheumatoid arthritis and those with the disease have higher blood levels of antibodies against Prevotella copri, a bacterial strain typically found in the gut. This study suggests that targeted therapies may be developed to prevent or treat the disease.
Most healthy infants can digest lactose as is, but excessive use of hypoallergenic and lactose-reduced formulas is noted. Analysis found 5.5% of formula purchased was hypoallergenic and 59% lactose-reduced, with lactose being only 47% of the carbohydrate source in formulas.
A recent analysis found that older U.S. adults with poor prognosis cancers had preexisting conditions such as functional impairment and difficulty with mobility before diagnosis. These conditions can impact their physical function and quality of life.
A recent study found no association between women's caffeine consumption and pregnancy or live birth rate after fertility treatments. However, moderate alcohol consumption (84g/week) was associated with decreased pregnancy and live birth rates in both men and women undergoing IVF/ICSI treatment.
A new potential antitumor drug, TRIP, causes rapid protein aggregation, hyperactivating the unfolded protein response and leading to programmed cell death in ovarian cancer cells. The Fe-S cluster biogenesis factor NUBP2 is identified as the probable starting point for the cellular processes triggered by TRIP.
SourceWiley·JournalAngewandte Chemie International Edition·TypeExperimental study·DateOct 12, 2022
Research reveals that individuals with inflammatory breast cancer are at a higher risk of brain metastases, which can lead to improved survival rates and quality of life. The study suggests that patients with triple-negative breast cancer face an even higher risk, emphasizing the need for earlier detection and more aggressive treatment.
Researchers analyzed 351 Chinese firms from 2006 to 2019, finding that female CEOs were associated with environmentally sustainable policies. The presence of female directors on the board strengthened this relationship. These findings suggest women's leadership can promote social and environmental benefits for stakeholders.
SourceWiley·JournalCorporate Social Responsibility and Environmental Management·DateOct 5, 2022
A study published in the Journal of the American Geriatrics Society found that individuals with type 2 diabetes who exhibit psychological resilience experience fewer hospitalizations, better physical functioning, and a lower likelihood of becoming frail. Psychological resilience also appears to mitigate aging-related concerns.
A recent analysis published in Contemporary Economic Policy found that 6-week paid family leave in California saved 339 infant lives from 2004-2008. The study also revealed a significant reduction in post-neonatal mortality rates for infants with married mothers and boys.
Research reveals forest elephants disperse seeds over long distances, aiding timber species regeneration. Logging can be part of conservation efforts when planned and legally conducted.
A study published in the Review of Development Economics found that investments in high-quality education for rural farm people are crucial to breaking the cycle of low soil health and human capital development. Annual returns to schooling in Malawi were 3-4% after correcting for various factors.
A collection of studies examines how horse owners' behaviors affect equine health, including colic recognition, disease treatment, and vaccination. Disseminating this knowledge could lead to improved veterinary care and positive changes in horse welfare.
A study found that excessive physical activity during adolescence is associated with abnormal leg alignment, which can develop into a physiological adaptation to load where the shin bone meets the knee. This abnormal alignment may increase the risk of future injuries and osteoarthritis if modified during critical periods of growth.
A successful collaboration implemented pediatric early warning systems (PEWS) in 36 Latin American hospitals, training over 11,100 clinicians and improving cancer outcomes. PEWS use was maintained for up to 18 months after implementation, with high-quality results.
The Event Horizon Telescope collaboration successfully captured an image of the black hole at the center of our galaxy, a major breakthrough in astrophysics. This achievement will enable scientists to test fundamental predictions of general relativity and gain insights into the formation and evolution of galaxies.
The US Supreme Court's decision to overturn Roe v. Wade may limit medical treatment options for patients with rheumatic diseases, as abortion bans take effect in more states. Providers will need to balance evidence-based clinical recommendations with personal and professional risks of violating reproductive rights.
A new guideline published in Clinical & Experimental Allergy aims to improve the testing process for penicillin allergies among patients. The guidelines provide recommendations on patient selection, risk stratification, and drug provocation testing, aiming to reduce errors and ensure accurate diagnosis.
Research suggests that stress can affect a woman's probability of becoming pregnant within a menstrual cycle. Women with higher levels of chronic stress had lower fecundability rates compared to those with lower levels. The study found that women with an allostatic load score of 5-6 had a 59% reduction in fecundability.
A cohort study of Chinese older adults found that sleeping for more than 8 hours increases dementia risk by 69% and going to bed before 9 PM doubles the risk. The study suggests monitoring cognitive function in those with prolonged sleep timing.
Researchers have found that delivering a cellular metabolite via tiny particles called nanoliposomes can augment the beneficial effects of certain anti-leukemia drugs in models of acute myeloid leukemia. The study also uncovered several mechanisms behind these effects.
A team of researchers has created a novel catalyst with single gold atoms that selectively converts carbon dioxide into methane. The catalyst, which anchors to an ultrathin zinc–indium sulfide nanolayer, exhibits high activity and CH4 selectivity when exposed to sunlight.
SourceWiley·JournalAngewandte Chemie International Edition·TypeExperimental study·DateSep 14, 2022
A new analysis reveals that mandatory prescription drug monitoring programs (PDMPs) do not significantly impact retail opioid sales across eight commonly prescribed opioids. The findings suggest that PDMP implementation is best considered as part of a broader policy response to the opioid crisis.
Researchers from the European Insomnia Network found that outdoor nighttime temperatures outside thermal comfort can affect human sleep. To combat this, try keeping a bedroom below 25 degrees Celsius, using fans instead of air conditioning, and staying hydrated during heatwaves.
New research published in Environmental Toxicology and Chemistry found that green household consumer products (HCPs) can be either less toxic or more toxic than their conventional counterparts. The study involved testing various HCPs on grass shrimp and Daphnia Magna, a type of freshwater crustacean.
Poor periodontal health is linked to a higher risk of cognitive decline and dementia. Tooth loss alone increases the odds of cognitive decline by 23% and dementia risk by 13%.
The International Journal of Dermatology calls on dermatologists to take action against climate change by reducing carbon emissions through increased use of telehealth. The authors also emphasize the need for funding prioritization for climate-health research to improve healthcare sustainability and decarbonize the profession.
A study published in the Journal of Bone and Mineral Research found that adults with osteoporosis are at a higher risk of developing cardiovascular disease. The research identified several key risk factors, including older age, smoking, and use of anti-hypertensive medications.
A recent study published in Arthritis & Rheumatology found that losing weight can help combat the structural defects of knee osteoarthritis. Researchers analyzed data from over 9,683 knees and discovered a significant association between reduced body mass index (BMI) and lower incidence and progression of knee osteoarthritis.
A new titanium-based photocatalyst overcomes production inefficiencies in polyethylene furandicarboxylate (PEF), a biobased plastic replacement for PET. The catalyst increases efficiency by shifting light absorption to the visible range, reducing unwanted byproducts and requiring less UV light.
SourceWiley·JournalAngewandte Chemie International Edition·TypeExperimental study·DateAug 26, 2022
A Japanese team has introduced a molecular cage with 'caps' that can confine certain rare-earth-metal ions, including lanthanum and europium, for isolation or recycling. The critical feature of the cage is its two 'caps' that cover the openings and bind to the ions through hydrogen bridges and electrostatic interactions.
SourceWiley·JournalAngewandte Chemie International Edition·TypeExperimental study·DateAug 22, 2022
Working-aged adults with and without a history of cancer reported healthier behaviors and steady health insurance status during the first year of the COVID-19 pandemic. The prevalence of unhealthy behaviors decreased, including insufficient sleep and smoking, while self-rated health improved among all groups.
A study found that elevated blood levels of chemokine CXCL9 predict the risk of osteoporotic hip fracture in men. Researchers discovered a significant association between CXCL9 and hip fractures in a cohort of Chinese men, highlighting the potential for early interventions targeting CXCL9 to prevent hip fractures.
Guidelines for diagnosing and managing Pollen Food Syndrome (PFS) have been developed to distinguish it from primary allergies and manage dietary restrictions. The guideline highlights the need for more research on health-related quality of life and novel treatments, including food immunotherapy.
Researchers found that adults with low blood urate levels are more likely to have low skeletal muscle mass and strength. This association is also linked to a higher risk of early death, particularly due to weight loss and adverse body composition.
A comprehensive review of water quality trading programs worldwide reveals that agricultural production remains largely unregulated, hindering their effectiveness. The authors suggest that nudging political will and creating regulatory drivers can help evolve water quality trading into a cost-effective pollution control instrument.
A new study found that 72% of methylmercury concentration variance in largemouth bass can be explained by land cover types. Monitoring efforts should focus on ecoregions with increased sensitivity to atmospheric mercury deposition.
A recent paper by Darren Grant found favoritism in order assignment in various contests, including Texas and West Virginia primary elections. The author applied statistical methods to detect this behavior, which was often overlooked despite its significant impact on outcomes.
A recent study published by Wiley suggests that biological sex differences are the primary reason for higher cancer rates in men compared to women. The study analyzed data from 171,274 males and 122,826 females aged 50-71 years and found that incidence was lower in men only for thyroid and gallbladder cancers.
A large population study found a 14% increased risk of developing Crohn's disease among children born via cesarean section. The study suggests an association between cesarean section and altered gut microbiome, warranting further research.
SourceWiley·JournalActa Obstetricia Et Gynecologica Scandinavica·DateAug 4, 2022
A new study published in Clinical & Experimental Allergy reveals a 4-fold increase in allergy clinics for children in the UK, but most are small and vary in services offered. The research highlights the need for standardized care through national networks and simulation training to ensure safe service provision.