A review in the Journal of Neurochemistry suggests a link between COVID-19 and Alzheimer's disease, with age being the largest contributing factor. Emerging evidence may further support this association, with research assessing influences on AD neuropathology.
Juvenile crown-of-thorns sea stars (COTS) exhibit high tolerance to heatwave conditions that cause coral bleaching and mortality. This finding suggests they may persist as major coral predators in reefs vulnerable to climate change, threatening coral health.
A new study found that diverse plant species mixtures increase plant productivity, invasion resistance, and soil nitrogen levels. Multispecies mixtures also drive different functions, with legumes benefiting productivity and water availability.
A new study found that an alternative model to identify patients with lung cancer eligible for screening was more accurate than the currently used method based on the United States Preventive Services Task Force (USPSTF) criteria. The PLCOm2012 models had higher sensitivity and identified more people with lung cancer eligible for scree...
A team of Chinese researchers has developed a bio-inspired approach to improve the performance of flexible sodium-ion batteries. By methylating the structural polymer in the hydrogel electrolyte, they significantly increase the salt stability, leading to better battery capacity and cycling performance. The modified hydrogel can absorb ...
Research published in European Journal of Neurology indicates that COVID-19 and COVID-19 vaccination have negligible effects on migraine severity. Among participants who reported worsening migraines, those infected were 2.5-times more likely to be concerned about migraine worsening than those vaccinated.
Rates of opioid prescribing to US adolescents have decreased in recent years, mainly for non-surgical procedures. Opioid prescribing for surgical indications has remained relatively stable during the same period. This analysis of Medical Expenditure Panel Surveys data from 2015-2020 reveals a significant shift in prescribing patterns.
Research in Seattle's Democracy Vouchers program found a significant increase in voter turnout, with candidates relying more on small contributions. The study suggests that public financing programs can help address problems of low voter turnout and disproportionate influence of big donors.
A new intervention for caregivers has been shown to reduce elder mistreatment of older adults with chronic illness, including dementia. The Comprehensive Older Adult and Caregiver Help (COACH) program provides personalized support to caregivers, reducing mistreatment rates from 22.5% to 0%.
Scientists have discovered a suitable combination of chemical compounds that can preserve adult zebrafish hearts for up to 5 days at -10°C. This breakthrough could potentially be used for the preservation of other organs before transplantation, revolutionizing organ donation and increasing the chances of successful transplants.
Researchers have developed a novel supramolecular memristor based on bistable [2]catenanes, which can achieve high-density storage and non-volatile memory capabilities. The memristors demonstrated at least 1000 erase-read-write cycles and switching times comparable to commercial inorganic memristors.
Researchers combined three highly potent cancer drugs in a single prodrug that is activated in tumor cells, resulting in improved efficacy and reduced side effects. The new approach has shown promise as a potential solution to reduce the burden on patients' bodies during cancer treatment.
A study found that 80.3% of patients with metastatic breast cancer who received standard care treatment with alpelisib developed hyperglycemia, with 40.2% experiencing serious hyperglycemia. Lifestyle interventions and medication may help improve blood sugar levels and reduce the risk of needing to discontinue the drug.
A randomized clinical trial shows cognitive-behavioral therapy (CBT) reduces fibromyalgia pain and improves daily living. CBT alters brain connectivity to reduce catastrophizing, a key contributor to fibromyalgia symptoms.
A new study uses AI to predict mortality rates in patients with hip fractures, identifying key biomarkers for poor outcomes. The model achieved accurate predictions using basic blood and lab test data as well as demographic information.
Research on sea-level rise's impact on freshwater mussels reveals that high salt concentrations can be toxic to young mussels. The study provides guidance for conservation programs addressing climate-induced sea level rise and saltwater intrusion, affecting numerous vulnerable species.
A recent clinical trial found that creatine supplementation significantly reduced post-COVID-19 fatigue and improved related symptoms such as loss of taste and breathing difficulties. Creatine levels in leg muscles and the brain also increased after 6 months of intake.
Researchers found that huckleberry patches and forestry road density significantly affect grizzly bears' mortality risk. Securing critical food resources through reduced human access near roads is crucial for bear conservation.
Palliative care and addiction experts agree that clinicians should increase monitoring and continue opioids without tapering in patients with advanced cancer who use stimulants. This approach prioritizes pain control and allows for individualized harm-reduction strategies.
Researchers have developed a new approach to treating herpes by inhibiting an enzyme that releases newly formed virus particles from infected cells. The inhibitors, made of oligosaccharides, significantly reduce the spread of the virus and may also impede cancer metastasis.
A study of 10,258 US adolescents found that victims and perpetrators of cyberbullying were more likely to experience eating disorder symptoms. Cyberbullying was associated with worrying about weight gain, low self-esteem, and body dissatisfaction.
A recent study found that pain in the lower limbs of children and adolescents may indicate the presence or risk of migraines. The study included 100 children with mothers who experienced migraines, with growing pains occurring in half of them. After five years of follow-up, headaches occurred in 76% of participants with growing pains.
Research finds antipsychotics used inappropriately among home-bound patients with Alzheimer's disease, leading to poorer patient outcomes. Commonly used antipsychotic quetiapine is often prescribed based on behavioral symptoms and limited daily activities.
Scientists introduce a novel approach to recover lithium from used LIBs by using aprotic organic solutions to avoid hydrogen gas production and simplify the process. The new method is efficient, inexpensive, and reduces waste, making it an attractive option for sustainable recycling of lithium-ion batteries.
A new artificial olfactory system, integrated on a single chip, detects food spoilage by identifying low levels of hydrogen sulfide and ammonia gases. The system tracks freshness scores in real-time during the spoilage process.
A team of researchers has discovered a particularly efficient molecular structure for solar energy storage materials, which could lead to more efficient solar energy harvesting. The new molecules were identified by screening over 400,000 molecules with the help of machine learning and quantum computing.
A recent analysis of published studies reveals a lack of evidence to determine the dosing, safety, and efficacy of medical marijuana or cannabis-containing products for managing symptoms experienced by children with cancer. The study found that cannabinoids performed better in managing nausea and vomiting, but data are lacking on their...
Most research focuses on treating existing mental health conditions rather than preventing them or promoting mental health. Depression and anxiety disorders are frequently researched outcomes. The findings reveal a lack of evidence-based interventions for child and adolescent mental health in low-resource settings.
New research published in Human Brain Mapping indicates that deafness does not affect the mechanisms and brain circuits supporting social skills. Deaf individuals show greater activation in regions involved in processing visual inputs like signs and lip reading.
A recent study found that cast immobilization is as effective as surgery in treating older adults with arm fractures. After one year, no statistically significant differences were found between the groups in terms of disability or range of motion. The study included 276 patients aged 70–89 years who suffered a distal radius fracture.
Researchers analyzed data from 31 studies and found that cattle face a higher risk of getting tuberculosis from wildlife through indirect interactions. Indirect interaction rates were 154 times higher than direct interaction rates.
The study found that racial and ethnic disparities in cardiometabolic diseases persisted despite social risk factors adjustments. Individuals with a more favorable social risk factor profile had lower rates of lifestyle risk factors and cardiometabolic diseases.
A large study found catheter ablation reduces dementia risk by 48% and death from any cause in patients with atrial fibrillation, regardless of age, sex, or health conditions. The procedure is an important consideration for treatment options.
Researchers developed a new strategy for T-cell-based immunotherapy using aptamers, which directly activates immune cells against cancer cells without genetic modifications. The innovative regulatory circuit establishes an artificial interaction between T cells and cancer cells.
Researchers have developed a molecular 'singlet oxygen battery' that can target and kill methicillin-resistant Staphylococcus aureus (MRSA) bacteria in deep tissue layers. The technology, which does not require external light or oxygen, is highly effective in treating pulmonary infections caused by MRSA.
Researchers found that bacteria with electrically conductive protein threads can corrode iron anaerobically, producing magnetite that facilitates further corrosion. The discovery has significant implications for corrosion protection and suggests taking material properties into consideration.
A study in Cancer Medicine reveals that access to assisted suicide does not decrease conventional suicide among patients with cancer. In fact, the percentage of cancer-associated deaths by assisted suicide increased over time, while conventional cancer-related suicides showed a downward trend.
A new tool called PRESTO identifies patients with psoriasis at high risk of developing psoriatic arthritis. The tool uses a mathematical model to estimate a patient's risk based on factors such as age, sex, family history, and disease severity.
Researchers have identified a protein called Hmga1 that may help prevent bone loss associated with postmenopausal osteoporosis. Increasing the expression of this protein in rats partially reversed bone loss in ovariectomized animals, suggesting its potential as a therapeutic target.
Researchers identified a mutation in the TMCO3 gene in two sisters with short stature, and found it regulates expression of proteins controlling bone growth. A mouse model lacking the gene confirmed its role in longitudinal growth.
A meta-analysis of multiple studies found no association between depression and anxiety and most types of cancer. However, the study found a link between depression and anxiety with a 6% higher risk of developing lung cancer and smoking-related cancers.
A new method called Degradation Upcycling (Deg-Up) recovers aromatic chemicals from polystyrene waste in a two-step process. This approach produces valuable chemicals for the cosmetics and pharmaceutical industries, offering a circular plastics economy solution.
A German research team has successfully developed a novel NMR technique to quantify acute-phase proteins in human serum, which can serve as markers for inflammatory diseases. The study found significant changes in specific acute-phase proteins in patients with COVID-19 or cardiogenic shock, and offers a diagnostic potential.
A study of 29 clinical trials found that MRg-A-SBRT significantly reduces urinary and bowel side effects in prostate cancer patients, with a 44% reduction in urinary and 60% reduction in bowel side effects. This technique uses imaging technology to accurately aim radiation beams at the prostate while avoiding nearby tissue.
A recent analysis of published and unpublished studies found that Functional Family Therapy is not consistently more or less effective than other treatments, including individual, family, and group interventions. The available evidence also raises concerns about the quality of the therapy's evidence base.
Children of parents with work-limiting disabilities experience less upward and more downward economic mobility compared to their peers. However, earlier access to disability insurance benefits may mitigate these disadvantages, as seen in a study of over 52,500 parent-child pairs in the US.
A randomized controlled trial found that Nurse-Family Partnership improved child language and mental health at age 2, with no increase in child injuries or maternal pregnancies. The study involved 739 participants and their children for 2.5 years, providing new evidence on preventing early adverse childhood experiences.
A study of 2,226 US participants found significant racial differences in post-retirement cognitive decline. White men experienced the most pronounced decline, whereas Black women showed minimal loss. College attendance was linked to greater cognitive decline after retirement.
Researchers developed nanoparticles that mimic the glycocalyx pattern to treat inflammatory bowel disease. The treatment reduced symptoms and inflammation in mice with IBD, with specific versions showing significant improvement.
A team of researchers has developed a new LED technology that can detect spoiled food by emitting light in two different wavelength ranges. The modified LEDs use perovskite materials to capture and convert light, allowing for non-invasive imaging of food freshness.