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Initiative seeks to bridge research and care related to mental illness

A new initiative brings together findings from mental health research and clinical care to develop better treatments for psychological disorders. The National Institute of Mental Health's Research Domain Criteria provides a framework for this approach, which is highlighted in an article about RDoC-oriented research.

SourceWiley·JournalPsychophysiology·DateFeb 16, 2016

Heart arrhythmia drug may fight plaque buildup in blood vessels

Researchers found that digoxin decreased levels of total cholesterol and triglycerides by 41% and 54%, respectively, in mice treated with high-dose digoxin. Digoxin also lowered LDL-cholesterol levels by 20%. The study suggests a potential link between the drug and reduced plaque buildup.

SourceWiley·JournalBritish Journal of Pharmacology·DateFeb 16, 2016

Discovery could lead to new treatment strategy against TB

Scientists have uncovered the 3D structure of an enzyme crucial for Mycobacterium tuberculosis survival. This discovery could lead to the development of new compounds targeting the ketol-acid reductoisomerase (KARI) enzyme, which is only present in bacteria and plants.

SourceWiley·JournalFEBS Journal·DateFeb 16, 2016

Photographs and music lessen patients' anxiety before surgery

A new study reveals that viewing photographs combined with listening to music can significantly reduce patients' anxiety before surgery. The findings suggest playing videos with photos and music in preoperative waiting rooms as a simple and affordable way to improve care without medications or invasive treatments.

SourceWiley·JournalJournal of Advanced Nursing·DateFeb 16, 2016

New evidence gives women informed choice in the prolapse surgery debate

A new Cochrane systematic review provides comprehensive insights into the surgical treatment of vaginal prolapse, comparing tissue repair with artificial mesh. The study found that while mesh reduces awareness of prolapse, its overall benefit is small and comes with increased risks, including reoperation and bladder injury.

SourceWiley·JournalCochrane Database of Systematic Reviews·DateFeb 8, 2016

Where infants sleep may affect how long they are breastfed

A study of 678 women found that frequent bed-sharing with infants and a strong motivation to breastfeed were linked to longer breastfeeding durations. This challenges recommendations against bed-sharing due to SIDS fears, suggesting these practices may hinder some mothers from achieving their breastfeeding goals.

SourceWiley·JournalActa Paediatrica·DateFeb 5, 2016

Cancer drug helps combat asthma in mice

Dasatinib, a cancer treatment, reduces inflammation and improves lung mechanics in mice with allergic asthma. The drug targets tyrosine kinases involved in asthma's signaling pathways.

SourceWiley·JournalBritish Journal of Pharmacology·DateFeb 1, 2016

Lupus may contribute to pregnancy-related complications

A new study found that lupus during pregnancy is associated with higher rates of preeclampsia, hypothyroid disease, stroke, and infection among women. The study also reveals worse infant outcomes, including preterm birth, infection, and mortality.

SourceWiley·JournalArthritis Care & Research·DateFeb 1, 2016

Using LEGO® blocks to develop stretchable electronics

Researchers developed a tensile tester using LEGO blocks, showcasing their potential for prototyping stretchable and flexible electronics. The innovative approach combines cost-effective machinery design with easy handling, comparable to commercial testing devices.

SourceWiley·JournalAdvanced Science·DateJan 19, 2016

When older adults stop driving, they may experience health declines

A new review suggests that stopping driving in older adults can contribute to various health problems, including depression. The decision to stop driving is often accompanied by declining cognitive and physical functions, highlighting the need for personalized plans to maintain mobility and social functions.

SourceWiley·JournalJournal of the American Geriatrics Society·DateJan 19, 2016

Socio-economic status may impact care of children with epilepsy

Children with lower socio-economic status have reduced access to neurology visits and increased emergency department visits due to transportation and employment barriers. These disparities highlight the need for additional support to reduce costly hospitalizations and improve specialist care access.

SourceWiley·JournalEpilepsia·DateJan 19, 2016

Too much sugar during adolescence may alter brain's reward circuits

A study in rats suggests that over-consuming sugary foods during adolescence can lead to reduced activity in the nucleus accumbens, a key hub of the brain's reward circuitry. This alteration could have long-lasting implications for individuals and may contribute to the development of substance abuse or eating disorders later in life.

SourceWiley·JournalEuropean Journal of Neuroscience·DateJan 19, 2016

Surgical treatment restores penis length

A new study reveals that surgical treatment can effectively restore penile length and improve erectile dysfunction in patients with Peyronie's disease. The 'sliding technique' and penile prosthesis implantation showed promising results, with an average lengthening of 3.2 cm.

SourceWiley·JournalBJU International·DateJan 13, 2016

Asthma in many adolescents is not an allergic disease

New research reveals that many adolescents with asthma do not have elevated levels of eosinophils or neutrophils, which are typically associated with inflammation. This finding has significant implications for the development of alternative treatments for asthmatics.

SourceWiley·JournalRespirology·DateJan 13, 2016

What's in store for survivors of childhood cancers that affect vision?

A new study reveals that adult retinoblastoma survivors are at higher risk of developing various medical problems, including second cancers, compared to unaffected individuals. Despite this, the majority of survivors report excellent general health and minimal long-term impact on their psychological or socio-economic outcomes.

SourceWiley·JournalCancer·DateJan 11, 2016