Articles tagged with Radiation Poisoning
Researchers have developed an oral therapy that protects healthy tissue from radiation while preserving radiation's ability to destroy cancer cells. The therapy, called XOlacta, is packaged in milk-derived extracellular vesicles and can be administered orally, reducing damage to tissues and preserving tumor treatment effectiveness.
A major new study has found that severe asthma patients are often battling other health conditions, with nearly all suffering from at least one major issue. The study identified three distinct profiles linked to how well asthma is controlled and the treatments needed, offering potential breakthroughs for improving care.
A patient with adenoid cystic carcinoma was successfully treated with step-and-shoot proton arc therapy at Corewell Health William Beaumont University Hospital. The treatment showed minimal side effects, including only light skin discoloration, and the patient remains cancer-free.
Filipino researchers have discovered that Taal volcanic ash can be used as a sustainable and lightweight alternative to expensive materials like concrete and lead. The natural presence of iron-rich minerals in the ash gives it strong radiation attenuation properties, making it effective for shielding against harmful X-rays and gamma rays.
A novel approach transforms treatment for pancreatic cancer by repurposing WR-2721 to protect healthy tissue from radiation damage. Phase 1 and 2 clinical trials are underway to evaluate the safety and efficacy of the new therapy, which could add years of survival to patients.
The AstroRad vest employs high-density polymers to shield vital organs from radiation exposure, addressing cancer and radiation sickness risks. The wearable technology has undergone extensive testing through the ISS National Lab, leading to significant enhancements in its design and functionality.
Researchers developed a highly accurate way to predict the best treatment for patients with meningioma based on patterns of gene expression. The new approach could change treatment for nearly 1 in 3 people with meningioma, reducing radiation side effects and improving patient outcomes.
Researchers studied genetic differences between two Chornobyl dog populations living near the nuclear power plant and 16.5 km away. They found significant genetic distinctions, with 391 outlier regions indicating potential genetic repair mechanisms. The study may provide insights into human adaptability to environmental disasters.
Opaganib, an oral small molecule pill, shows potential as a nuclear radiation injury therapeutic for homeland security medical countermeasures and antitumor radiotherapy. The compound protects normal tissue from radiation damage and improves antitumor activity and response to chemoradiation.
Researchers at Ohio State University Wexner Medical Center are developing non-invasive biomarkers for radiation exposure using Raman spectroscopy and mass spectrometry-based methods. The project aims to improve early detection and risk assessment of radiation exposure, which can lead to serious health problems and delayed consequences.
A new testing method has shown promise in rapidly identifying radiation sickness based on biomarkers measured through a single drop of blood. The test uses microRNAs to quantify the actual radiation dose absorbed, allowing for early and real-time identification of the condition to enable timely clinical interventions.
A UMass Amherst researcher argues that a historical investigation error led to the adoption of the LNT model, which challenged fundamental beliefs about ionizing radiation effects. The corrected research supports a threshold rather than linear dose response for carcinogens.
Long-term clinical data supports the efficacy of PRRT in treating neuroendocrine tumors, improving tumor response rates and progression-free survival. To minimize toxicity, steps such as timing of therapy, patient selection criteria, dose optimization, and adequate monitoring can be taken.
Researchers found that weak doses of gamma radiation increase the lifespan of drosophila flies by 7.6% in females and 3.4% in males. The study suggests that understanding the genetic mechanisms behind this effect could lead to new ways to prevent aging in humans.
A new study by Rutgers researchers reveals that eliminating the eEF2K enzyme could strengthen healthy cells, making them resilient to cancer treatment. This breakthrough may lead to more powerful treatments with fewer debilitating side effects, paving the way for improved cancer therapies.
A study in Nature Medicine reveals that boosting a protein pathway in the body's blood-making system can protect against radiation poisoning. The researchers found that pharmacologic enhancement of the Thbd-aPC pathway can accelerate recovery of hematopoietic progenitor cell activity and reduce harmful effects in mice.
A two-drug combination therapy, involving a fluoroquinolone antibiotic and rBPI21, has shown promising results in mice with radiation exposure. The treatment was effective even when administered a day after the exposure, offering hope for rapid response to public health threats.
Hermann Muller knowingly lied about safe levels of radiation exposure, says UMass researcher Edward Calabrese. Muller's suppression of evidence led to the adoption of a linear dose-response model that has shaped radiation and chemical exposure regulations.
A study on Alexander Litvinenko's care reveals that hospital staff involved in routine daily activities, such as handling patient blood and urine samples, were at higher risk of radiation contamination. The findings suggest that more attention should be given to infection control practices during these daily activities.
Researchers discover natural compound acetyl resveratrol protects mice from radiation damage, potentially overcoming existing drug's limitations. The substance can be easily produced in large quantities and administered orally.
A recent study found that combining radiation and chemotherapy for nasopharyngeal carcinoma increases treatment-related toxicities and non-cancer deaths. Patients treated with combined therapies experienced a higher acute toxicity rate compared to those treated with radiation alone.
Researchers at UNC Health Care have identified a simple, non-toxic pill that decreases radiation toxicity when given after radiation exposure. The drug, called PQ, temporarily stops bone marrow cells from dividing, protecting against radiation-induced damage.
Researchers found that inhibiting NF-kappa B reduced radiation toxicity in zebrafish embryos, offering a potential therapeutic strategy for cancer patients receiving radiation therapy. The study also suggests that downmodulating NF-kappa B activity may be more beneficial than completely ablating it to protect against radiation effects.
Researchers identified a gene expression profile associated with late radiation toxicity, correctly classifying 63% of patient populations. The study suggests that some patients are genetically predisposed to develop late-radiation toxicity and provides clues about molecular pathways involved.
Women with BRCA 1 or 2 mutations may not have to fear radiation therapy due to no increased incidence of side effects. The study suggests similar recurrence rates and survival after five years, with additional treatment keeping cancer in check.
TAPET technology, a genetically altered Salmonella bacteria, shows improved antitumor activity when combined with radiation therapy. The NIH/NCI-funded SBIR grant aims to confirm this benefit in animal studies and develop a 'triple play' treatment for solid tumors.
Researchers found that combining low doses of angiostatin with standard radiation therapy improves response rates without increasing toxicity. The combination causes significant growth inhibition in animal models, even in mice with large tumors.
Researchers have found that radiation exposure can be passed down through generations, affecting cell growth and reproduction. The study used a sensitive model to demonstrate that male mice exposed to radiation may pass on detrimental effects to their children, grandchildren, and great-grandchildren.
Researchers at the University of Pennsylvania School of Medicine have identified a novel death-receptor gene called KILLER/DR5 that responds to chemotherapy and radiation by killing cancer cells. The discovery provides new insights into how cancer cells are killed after treatment, with potential implications for improving cancer therapy.