A retrospective study of 1407 VNS Therapy patients found that reducing antiepileptic medications did not impair seizure control. The study analyzed changes in medication use and seizure rates over one year, with no significant differences between groups.
A new study shows that VNS Therapy is more effective in treating epilepsy patients when used earlier in their treatment course, resulting in a three-fold improvement in seizure control. The therapy also improves quality of life indicators such as alertness, mood, and verbal communications.
A new study suggests that routine overnight EEG monitoring is unwarranted for autistic children, as the incidence of Landau-Kleffner syndrome is miniscule. The study found that only a small percentage of patients with autism spectrum disorder exhibit abnormal EEGs during sleep.
A retrospective review of studies on psychological interventions found no direct impact on seizures or quality of life among patients with epilepsy. However, some promising indications were noted regarding reduced anxiety and improved medication compliance.
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Only 25% of patients have been seizure-free for the past year, with many experiencing frequent seizures despite medication attempts. Vagus Nerve Stimulation Therapy (VNS) has shown promise in reducing seizures and improving quality of life.
A study found that vagus nerve stimulation (VNS) increases blood flow in thalamic areas of the brain, leading to improved seizure control. VNS was shown to reduce seizures by up to 91% in patients with partial epilepsy.
The new guidelines recommend increasing use of single antiepileptic drugs before combination therapies, while also addressing special needs for women and older adults. Estimated 2.3 million Americans have epilepsy, with half being female.
Vagus nerve stimulation (VNS) therapy is safe, well-tolerated, and highly effective in reducing seizure frequency in children with refractory epilepsy. The study found significant improvements in quality of life, including alertness, verbal communication, and school performance.
SourcePorter Novelli·JournalJournal of Child Neurology·DateNov 12, 2001
A study published in Pediatrics found that over half of children who followed a ketogenic diet experienced at least a 50% reduction in seizures for three to six years after stopping the diet. Many children were also free from anticonvulsant medication and seizures entirely.
SourceJohns Hopkins Medicine·JournalPEDIATRICS·DateOct 1, 2001
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A new study finds that administering benzodiazepines to patients with status epilepticus en route to the hospital can significantly reduce seizures. Lorazepam was found to be at least as effective, if not more so, than diazepam in treating seizures.
SourceUniversity of California - San Francisco·JournalNew England Journal of Medicine·DateAug 29, 2001
A new study shows that paramedics can effectively treat patients with acute and prolonged seizures using injections of benzodiazepines. Lorazepam was found to be more effective in stopping seizures than diazepam, with 59% of patients responding to the treatment.
SourceNIH/National Institute of Neurological Disorders and Stroke·JournalNew England Journal of Medicine·DateAug 29, 2001
A team of researchers led by Louis J. Ptacek identified a novel gene, mass1, responsible for audiogenic reflex epilepsy in the Frings mouse strain. The gene was found to be mutated in mice with spontaneous seizures triggered by loud noises.
SourceHoward Hughes Medical Institute·JournalNeuron·DateAug 29, 2001
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Researchers at Emory University found that temporal lobectomy significantly reduces complex partial seizures in patients with temporal lobe epilepsy (TLE) who cannot be controlled by medication. However, the procedure is less effective in reducing generalized tonic-clonic seizures, also known as grand mal seizures.
SourceEmory University Health Sciences Center·JournalNeurology·DateDec 24, 2000
A new study by the University of Michigan found that a significant proportion of people with epilepsy may also have undiagnosed sleep apnea, which can disrupt brain function and exacerbate symptoms. The study suggests that addressing sleep apnea through lifestyle and medical interventions may help improve seizure control and quality of...
SourceMichigan Medicine - University of Michigan·JournalNeurology·DateOct 9, 2000
The American Academy of Neurology and the Child Neurology Society recommend EEG evaluation for children with a first nonfebrile seizure, providing insights into seizure type and potential recurrence risk. The guidelines also emphasize individualized evaluations and future research directions.
SourceAmerican Academy of Neurology·JournalNeurology·DateSep 11, 2000
A new study published in Neurology demonstrates that oxcarbazepine is safe and effective enough to be used alone in patients with partial epilepsy who do not respond to other anti-epileptic drugs. The results show that 12% of patients were seizure-free during a four-month trial, offering new hope for those struggling with the condition.
SourceMichigan Medicine - University of Michigan·JournalNeurology·DateJun 25, 2000
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A study by Johns Hopkins Medicine found that 31% of recent popular press articles on epilepsy contained gross mistakes, including inaccurate science and exaggerated treatment claims. The print media often reflect and shape views about epilepsy, but also perpetuate misconceptions that can shame patients.
SourceJohns Hopkins Medicine·JournalNeurology·DateMay 22, 2000
Researchers at Mayo Clinic have discovered a significant link between major depression and seizures in older adults. The study, published in Annals of Neurology, found that individuals with a history of major depression were six times more likely to experience a seizure after age 55.
SourceMayo Clinic·JournalAnnals of Neurology·DateMar 8, 2000
Researchers at the University of Florida have developed a technique to predict certain types of epileptic seizures minutes to hours before they occur. By analyzing brain electrical signals using mathematical formulas from chaos theory, they can identify warning signs of an impending seizure and potentially prevent it with medication or...
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A new study published in Neurology found that lamotrigine significantly reduces partial seizures and secondary generalized seizures in children. The medication has been proven safe and effective, allowing children to participate in daily activities without drowsiness.
SourceAmerican Academy of Neurology·JournalNeurology·DateNov 9, 1999
Researchers at U of T used nonlinear dynamics techniques to predict seizures and identified a dynamic regime - type III intermittency - that takes place during seizures. This approach may improve techniques to control the brain's transition to seizure, offering new hope for patients with intractable epilepsy.
SourceUniversity of Toronto·JournalEuropean Journal of Neuroscience·DateJul 27, 1999
A recent AAP recommendation suggests that young children with simple febrile seizures do not need anticonvulsant medication, instead aiming to prevent unnecessary testing and drug therapy.
SourceUniversity of Kentucky Medical Center·JournalPEDIATRICS·DateJun 28, 1999
A recent study published in the Journal of the American Medical Association found that tens of thousands of hospital patients are improperly treated for hyponatremic encephalopathy, a potentially life-threatening condition caused by low salt concentrations. The correct treatment involves increasing patients' salt concentration intraven...
SourceUniversity of California - San Francisco·JournalJAMA·DateJun 23, 1999
A new study at Johns Hopkins and the University of Maryland provides a tool for physicians to evaluate an epilepsy patient's risk of having an accident while driving. The study found that four illness-related characteristics can predict accidents, including the length of time between seizures.
SourceJohns Hopkins Medicine·JournalNeurology·DateApr 20, 1999
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Scientists at Harvard Medical School have discovered that a member of the MAP kinase family, ERK, may act as a molecular gatekeeper activating excitotoxic pathways. This finding could lead to new drug targets against stroke and other neurodegenerative diseases.
SourceHarvard Medical School·JournalProceedings of the National Academy of Sciences·DateSep 29, 1998
A unique gel formulation of diazepam has been found to reduce the severity of acute repetitive seizure episodes in both children and adults. The treatment, administered through a Quick-Dose delivery system, protects patients from seizure recurrence and enables caregivers to administer treatment privately.
SourceNIH/National Institute of Neurological Disorders and Stroke·JournalNew England Journal of Medicine·DateJun 24, 1998
The RADARS study found rectal diazepam gel to be effective in reducing seizure frequency and improving outcomes for patients with acute repetitive seizures (ARS). Administered by caregivers, the treatment demonstrated minimal potential for serious adverse events, making it a cost-effective option.
SourceNIH/National Institute of Neurological Disorders and Stroke·JournalNew England Journal of Medicine·DateJun 24, 1998
Treating people with epilepsy or seizures who are in remote locations like space, underwater or extended airline flights may be possible through telemedicine. Sleep deprivation and weightlessness can provoke seizures during travel.
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A new study by Columbia University researchers establishes the first mathematically sound definition of epilepsy, requiring two unprovoked seizures for a diagnosis. The study found that patients who have had two seizures are at high risk of recurrence, with a 73% chance of having a third seizure within five years.
SourceColumbia University Irving Medical Center·JournalNew England Journal of Medicine·DateFeb 11, 1998
Researchers are documenting the existence of seizure-alert dogs that claim to detect seizures before they strike, offering hope for people with epilepsy. The study aims to determine if these phenomena are real and reliable, and how dog trainers approach training such dogs.
A new vagus nerve stimulator device has been shown to prevent epileptic seizures in over 30% of patients, with some becoming completely seizure-free. The device, which is battery-operated and inserted just below the collarbone, sends electric current to stimulate the vagus nerve without impairing heart rate or cardiac cycles.
SourceUniversity of North Carolina at Chapel Hill·JournalSeizure·DateAug 13, 1997
Researchers at KU Medical Center developed a technique predicting seizures by analyzing brain activity, potentially leading to new treatment options for patients with epilepsy. The algorithm measures seizure and non-seizure components, allowing for up to three-minute warning before a seizure occurs.
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Researchers at UC Davis found that diets deficient in amino acids can increase seizure severity, shorten time before seizures occur and reduce chemical stimulant needed. The study suggests specific brain regions are influenced by diet components, with implications for treating epilepsy, particularly in underdeveloped countries.