Articles tagged with Drug Design
A human factors approach to interface design significantly reduces errors in patient-controlled analgesia. The redesigned device shows a 55% reduction in errors, an 18% improvement in performance time, and a strong preference among nurses.
Researchers have discovered the precise three-dimensional shape of the complex between tamoxifen and the estrogen receptor. This clarifies how estrogens turn on genes and shows precisely how tamoxifen blocks this process, setting the stage for intentional drug design with precise action.
The American Association of Pharmaceutical Scientists has recognized eight researchers with awards for their outstanding contributions to the field. Sung Wan Kim received the AAPS-Dale E. Wurster Research Award in Pharmaceutics for his work on controlled drug delivery systems, while Vincent H.L. Lee was honored with the Distinguished S...
A new approach to experimentation using computer simulation and rapid prototyping could significantly reduce development cost and time in the computer, pharmaceutical, and chemical industries. The study found that firms can save millions of dollars by switching between these methods at the optimal point.
Researchers at Yale University are using computer simulations to design more effective pharmaceuticals by optimizing chemical binding to target proteins. This approach has the potential to improve treatment outcomes for diseases such as dementia, diabetes, and spinal cord injuries.
The Cook GR II Coronary Stent has received FDA clearance for treatment of acute or threatened vessel closure in patients with failed interventional therapy. The stent features a flat metal design and low profile for improved radial strength and trackability.
A prison-release program for HIV-positive women successfully links clients with medical care and substance-abuse treatment on release from prison. The program resulted in a more than 50-percent decrease in the recidivism rate, with women experiencing reduced rates of return to prison within six months and one year.
A large study published in the New England Journal of Medicine found that patients with mild asthma do not need to take albuterol regularly. The study suggests that using albuterol only during symptoms can effectively manage asthma without negative consequences.