Articles tagged with Blood Cells
Researchers found that eliminating or overexpressing the cdx4 gene affected blood-cell formation and Hox gene expression in zebrafish. The study's findings could help reveal how cdx4 fusions disrupt normal hematopoiesis and contribute to human leukemias.
Researchers have discovered a genetic signature, known as the IFN expression signature, associated with severe lupus symptoms. This signature is linked to interferon activity and has implications for developing new therapies to block IFN pathways in patients with severe lupus.
Researchers developed a system to study blood vessel development without mural cells, revealing that angiopoietin-1 partially restores large vessel structure. The study suggests Ang1 is crucial for normal vessel stability and highlights the importance of pericytes in maintaining vascular networks.
A recent study has found that gut bacteria interact with the intestine to regulate blood supply, with Bacteroides thetaiotaomicron stimulating blood vessel development. The research suggests a key developmental program shared by intestinal bacteria and their host is essential for healthy development.
Researchers found that cord blood cells improved neurological function in rats with traumatic brain injury, suggesting a new approach for treating this condition. The cells helped promote brain self-repair by stimulating trophic factors and cytokines, which led to better movement, balance, and reflex responses.
Researchers discovered the ancestral role of VEGF protein guiding developing blood cells to their destinations. The findings suggest that blood vessels may have evolved from blood cells, a theory supported by studies on fruit fly embryos.
Dartmouth Medical School biochemists identify a transport receptor that selects soluble proteins for export from cells, resolving a long-standing puzzle. The discovery opens up new avenues for understanding protein secretion and its role in diseases such as hemophilia.
Researchers found that human umbilical cord blood cells improved motor and sensory abilities in rats after stroke, even when administered a week after onset. The study suggests these cells may be used to treat early stroke and other traumatic brain injuries through less invasive IV administration.
Researchers found that bone marrow-derived cells contribute to tumor blood vessel formation and promote growth. Targeting specific VEGF receptors blocks tumor formation, offering potential new therapeutic approaches.
Researchers discovered that blood vessels signal pancreatic cell differentiation, challenging the long-held assumption that organs develop independently. The study found that removing blood vessels from pancreatic tissue disrupts normal gene expression and insulin production.