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Overactive microRNAs block fat cell development in progeria

A new study found that miR-145-5p and miRNA-27b-3p interfere with fat cell formation in children with Hutchinson-Gilford progeria syndrome, a rare and fatal premature aging disorder. These microRNAs silence genes required for fat cell growth and function, suggesting they could be a promising therapeutic strategy to restore fat tissue.

Missing protein keeps mice slim, even on a high-fat diet

Researchers found that CD44-deficient mice stayed lean despite a high-fat diet, while control mice developed obesity. The study suggests CD44 inhibitors could serve as a complementary treatment for obesity and related metabolic disorders.

Apple iPhone 17 Pro

Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.

New cells could be key to treating obesity

Researchers have identified a population of mesothelial-like cells in omental adipose tissue that limit fat cell formation, offering new insights into the mechanisms underlying obesity. These cells secrete Insulin-like Growth Factor Binding Protein 2, which inhibits adipogenesis and regulates metabolic behavior.

SAMSUNG T9 Portable SSD 2TB

SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.

Turning an old enemy into a helpful friend

A study by EPFL researchers found that the KRAB domain-containing zinc finger protein Zfp30 initially repressed a retrotransposon, but later evolved to activate genes involved in fat-cell formation instead, surprising scientists

CalDigit TS4 Thunderbolt 4 Dock

CalDigit TS4 Thunderbolt 4 Dock simplifies serious desks with 18 ports for high-speed storage, monitors, and instruments across Mac and PC setups.

Red wine, fruit compound could help block fat cell formation

A compound found in red wine and fruits can block the development of immature fat cells, according to a Purdue University study. The compound, piceatannol, alters gene expressions and insulin action during adipogenesis, delaying or inhibiting the formation of mature fat cells.

Fat gene discovered

Researchers identify PPARgamma2 as critical player in fat cell differentiation process. The discovery provides a molecular target for rational drug design to combat obesity.