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Life Sciences

Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.

447,757 articles | 2542 topics

Health and Medicine

Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.

431,843 articles | 751 topics

Social Sciences

Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.

260,756 articles | 745 topics

Physical Sciences

Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.

257,913 articles | 1552 topics

Applied Sciences and Engineering

Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.

225,386 articles | 998 topics

Scientific Community

Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.

193,043 articles | 157 topics

Space Sciences

Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.

29,662 articles | 175 topics

Research Methods

Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.

21,889 articles | 139 topics

Mathematics

Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.

3,023 articles | 113 topics

Do genes respond to global warming?

A recent study published in PLOS Biology found that climate change can shape genetic diversity in mammals. Researchers analyzed fossil samples and contemporary data from two mammal species, the Montane vole and northern pocket gopher, and discovered that climate-induced habitat alterations influenced variation in genetic diversity.

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UAB creates the first Internet server to search for genetic diversity

Researchers at Universitat Autonoma de Barcelona have developed the PDA web service, allowing scientists to analyze genetic diversity in different individuals and species. The server enables the search for small variations in genomes, providing valuable information for studying illnesses with a genetic origin.

Some re-established elk herds lack genetic diversity of ancestors

Research at Purdue University found that re-established elk herds in Pennsylvania and California have lost significant amounts of genetic diversity due to poor management and small reintroduction numbers. This loss can make them more vulnerable to environmental changes, highlighting the importance of effective herd management.

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Genes that paint fly derrieres hint at convergence

Researchers found a common gene, Bric-a-brac2, responsible for diverse pattern and color pigmentation across 13 fruit fly species. The study suggests that similar genetic mechanisms govern body plans in related animals.

New study rebuts claims about Icelandic genetic heterogeneity

Researchers from deCODE Genetics and the University of Oxford found that genetic drift, not admixture, has shaped Iceland's gene pool. The study suggests that small effective population size and relative isolation have contributed to Iceland's unique genetic characteristics.

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Maize's starch pathway found limited

The study found limited genetic diversity in maize's starch pathway, making it harder to increase yields. To address this, researchers suggest incorporating genes from teosinte or using transgenics as alternative methods for improving crop diversity and productivity.

DNA may hold clues to Red Tide origins

Campbell and co-investigator John Gold aim to pinpoint geographic points of origin for toxic algae using hypervariable DNA markers. They hope to predict when and where red tides may occur along the Texas coast by analyzing genetic diversity within bloom populations.

New threat to commercial fishing

Researchers found a decline in genetic diversity in Tasman Bay's New Zealand snapper population, starting from the 1950s when it began to be commercially fished. The 'virgin' population showed a significant decline in six of seven microsatellite loci, raising concerns about the sustainability of commercial fishing industries.

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Fragmentation can make seedlings wimpy

Research in tropical dry forests reveals that fragmentation decreases seedling quality, with reduced germination rates and smaller leaves. Despite the negative effects, isolated trees can still serve as genetic stepping stones for pollinating moths and gene flow between populations.

Discovery overturns long-held genetic belief

Scientists challenge textbook example of natural selection eliminating variation from closely linked genes; Chromosome 4 has multiple regions with varying levels of recombination. High levels of genetic diversity are found on this previously thought 'non-recombining' chromosome.

Giant pandas have plenty of genetic diversity

Research found giant pandas have moderate genetic diversity compared to other carnivores, with some populations showing signs of isolation. To ensure the species' survival, conservation efforts focus on restoring gene flow among populations through natural corridors and ecological restoration.

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Human Genome project leaves much of human variation unsampled

The Human Genome project has a limited representation of global genetic diversity due to an inadequate sample size from sub-Saharan Africa. This exclusion ignores the worldwide genetic variation and evolutionary history of the human species, according to anthropologist Todd R Disotell.

Success of introduced Argentine ants tied to reduced genetic variation

Biologists at UCSD discovered that the Argentine ant's ability to thrive in California is due to its low genetic diversity, which allows it to recognize and accept individuals from the same colony. This has led to the formation of a single, large 'supercolony' that dominates native species.

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Researchers take major step in identifying gene differences

A study analyzing human genes reveals a wide range of sequence changes associated with blood pressure control and potential disease susceptibility. The research identified 50% of the changes that lead to protein structure alterations, suggesting their involvement in human disease.

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Scientists Issue Call To Save Bornean Rhino

The study confirms the Bornean rhino's genetic distinctness from other Sumatran rhinos, with a 1% difference in genetic code, making interbreeding unlikely. Only 50-100 animals remain, and conservation efforts are needed to protect them.

Humble Pocket Gophers Shed Light On The Genetic Fortitude Of Cheetahs

A recent study using pocket gophers found that individuals with low genetic variation accepted skin grafts from each other, while those with higher genetic diversity rejected them. This suggests that cheetahs and other genetically impoverished species may be more vulnerable to disease outbreaks.

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