Articles tagged with Chromatin
Researchers found that mutated MeCP2 protein represses genes, specifically targeting imprinted genes like DLX5, leading to misregulation of neurotransmitter GABA production. The study links specific defects in chromatin folding to Rett Syndrome for the first time.
Researchers at The Wistar Institute have discovered a family of molecular complexes involved in the repression of extensive sets of tissue-specific genes. These complexes share two core subunits, including histone deacetylase and BHC110, which operate as co-repressors to maintain gene silencing.
New research at the University of Illinois Chicago found that chromatin, not proteins, provides structural support for chromosomes during cell division. The study used a novel methodology involving DNA digestion and glass tube pipettes, which may help unlock the puzzle of how cells divide.
Researchers have found a new piece of the gene expression puzzle, revealing how histone proteins interact with each other and with other molecules to regulate gene activity. The discovery sheds light on potential causes of male infertility and highlights the complex mechanisms at play in chromatin.
A recent discovery by Dr. Kathrin Muegge and colleagues has revealed that a protein called Lsh is required for normal genome-wide methylation during development. The study suggests that chromatin structure plays a crucial role in regulating DNA methylation, which is essential for gene expression and cellular function.