Articles tagged with Aneurysms
Researchers at Michigan Medicine have made significant discoveries on the formation of abdominal aortic aneurysms (AAAs), a leading cause of death worldwide. Two new studies suggest that neutrophils, a type of white blood cell, play a crucial role in AAA formation, particularly in the early stages of the condition.
Researchers developed a classification system to treat thrombotic aneurysms, finding that one-third can be treated surgically with conventional clipping. The study also discovered that bypass and occlusion procedures yield more favorable results for unclippable aneurysms.
A lab study found that administering male sex hormones to female mice increases their susceptibility to developing abdominal aortic aneurysms. The goal now is to identify the target of these hormones to develop drugs that can lower the incidence of life-threatening aneurysms.
Researchers at the Mayo Clinic have identified a specific genetic variation associated with a 10-fold increased risk of a ruptured brain aneurysm. This discovery could lead to the development of a fast and inexpensive blood test to predict stroke risk, saving thousands of lives annually.
A study published in Annals of Neurology found a strong association between dolichoectasia, a rare blood vessel disorder, and small vessel disease, a significant cause of lacunar or 'mini' strokes. The research may offer new insights into the causes and treatment of this condition.
The American College of Physicians recommends one-time ultrasound examination for abdominal aortic aneurysm screening in men aged 65-75 who are smokers. New evidence suggests that large abdominal aneurysms may reduce deaths from ruptured aneurysms. Meanwhile, a study found that the COX-2 inhibitor rofecoxib increases heart attack risk ...
Researchers at Johns Hopkins Medicine have discovered a new syndrome characterized by wide-set eyes, cleft palate, or split uvula, and aggressive swelling of the aorta. Early diagnosis and treatment can prevent aortic rupture and save lives, with surgery often successful if performed promptly.
Researchers found that estrogen significantly reduces MMP-9 enzyme activity in male rat aortas, leading to smaller aneurysms and less damage. The study suggests that host environment is the critical factor in aneurysm formation, with male rats more prone to AAA development.
A new study suggests that endovascular surgery (EVAR) reduces mortality rates by around two-thirds compared to conventional open surgery for large abdominal aortic aneurysms. The study involved over 1000 patients and found that EVAR was associated with lower 30-day mortality rates, but also led to more secondary procedures.
Researchers discovered a link between aneurysm formation and the activation of an asthma inflammation gene. Blocking this pathway may prevent or slow aneurysm progression, potentially using anti-inflammatory drugs used in cardiovascular disease treatment.
A study of 32,372 patients found that coronary artery aneurysms are associated with a high 5-year mortality rate of 29.1%. Experts emphasize the need for aggressive monitoring and modification of coronary risk factors for all patients with angiographic evidence of aneurysms, regardless of size.
A UH-led group of experts has developed new stent designs to minimize complications in the treatment of aortic abdominal aneurysm (AAA) and coronary artery disease (CAD). These innovative stents feature genetically engineered cartilage cell-coated designs and novel mechanical properties that mimic human arteries.
In a groundbreaking clinical trial, OHSU doctors used the Onyx Liquid Embolic System to repair aneurysms in patients with promising results. The new procedure uses a catheter to inject a liquid that solidifies into a spongy mass, sealing off the defect and preventing future ruptures.
The study found that mortality rates are significantly lower for patients with a vascular surgeon performing the operation. High-volume surgeons and hospitals resulted in better outcomes, suggesting that experience counts when it comes to treating aortic aneurysms.
For the first time, a US patient's entire aortic arch has been successfully repaired using this technique. The procedure minimizes complications and allows patients to recover quickly, with a lower risk of death or complications compared to traditional open surgery.
The study found that uninsured patients with abdominal aortic aneurysms are more likely to be diagnosed late, leading to a higher mortality rate. Insured patients who received timely treatment had lower death rates, highlighting the importance of access to regular medical care.
Researchers found that age, gender, and body size are better predictors of aortic aneurysm than previously thought. Atherosclerosis and related risk factors only accounted for 3% of cases, suggesting genetic diseases like Marfan syndrome may play a more significant role.
The ISUIA study found that smaller aneurysms than previously thought may warrant treatment, and endovascular treatment resulted in lower disability and death rates compared to open brain surgery. This suggests additional advantages for patients with specific characteristics.
An international study found that smaller aneurysms (less than seven millimeters) are at low risk for rupture, and patients' age, location of the aneurysm, and history of previous ruptures are key factors to consider. The study also showed that treatment risks increase substantially after age 50 and older.
Detachable coil embolization is a new approach to treating brain aneurysms, offering less invasive treatment with shorter recovery times. The procedure has been shown to reduce mortality rates by 22.6% compared to traditional open surgery for patients with ruptured aneurysms.
The Northwestern Memorial Hospital is leading an international brain aneurysm study to confirm a familial link and identify specific genes responsible for the development of intracranial aneurysms. The goal is to prevent and treat aneurysms early, reducing premature mortality and morbidity associated with this type of stroke.
Researchers have developed a non-invasive imaging method that predicts abdominal aortic aneurysm rupture risk better than traditional methods. The method, which analyzes aneurysm wall stress, was found to be 25 times more accurate in predicting rupture risk than maximum diameter.
A new study led by Alan Scott found that screening men for aortic aneurysms can significantly reduce aneurysm-related deaths. The Multicentre Aneurysm Screening Study showed a relative risk reduction of around 50% among screened men, with a corresponding decrease in absolute risk.
A recent study published in The Lancet found that endovascular coil therapy is significantly more effective than neurosurgical clipping in treating subarachnoid hemorrhage. For patients with suitable conditions, the treatment resulted in a relative reduction of 25% in risk of dependency or death after one year, as well as an absolute r...
The International Subacrachnoid Aneurysm Trial (ISAT) found that inserting platinum coils via an artery reduced dependency or death by nearly a quarter and absolute risk by seven percent compared to surgery. The study involved over 2,000 patients in 43 centers across Europe, North America, and Australia.
The International Subarachnoid Aneurysm Trial (ISAT) study found that coiling significantly reduces death and disability from brain aneurysms. Over 2,000 patients were treated with either surgical clipping or coiling, resulting in favorable outcomes for those receiving the coils.
A new endovascular prosthesis has demonstrated promising results in treating life-threatening conditions such as thoracic aortic aneurysms and dissections. The treatment has shown decreased morbidity and mortality rates, making it available to patients who are not suitable for conventional surgical repair.
A new study suggests that smaller aneurysms are often safer left untreated, with potential benefits including reduced risk of complications and cost savings. The research found nearly 98% survival rate among patients undergoing AAA surgery at participating VA hospitals.
Researchers used EBCT to screen coronary arteries for calcium deposits in former Kawasaki patients. Four out of 18 participants showed positive results, indicating moderate to high risk of coronary artery disease. The study suggests that EBCT can be an effective non-invasive screening method for detecting artery disease in these patients.
The study identified metalloproteinase-9 (MMP-9) as a key player in the development of abdominal aortic aneurysms. The researchers found that MMP-9 production was significantly reduced in patients who took doxycycline, suggesting a potential therapeutic strategy for preventing aneurysm expansion.
A study by UB neurosurgeons found that cigarette smoking is associated with larger brain aneurysms, which can lead to life-threatening complications. The research, published in the journal Neurosurgery, showed that smokers were more likely to develop large aneurysms than non-smokers.
A study by Hennepin County Medical Center found that cocaine users are at a higher risk of developing aneurysms in their heart arteries, with 30% of participants showing the condition. The study suggests that cocaine use causes blood vessel damage and accelerates atherosclerosis, leading to increased cardiovascular health problems.
Researchers found that treating small, asymptomatic, unruptured cerebral aneurysms may increase health risks and death. The study's complex analysis suggested that in some cases, aneurysm treatment is unnecessary, highlighting the need for personalized care.
A study published in The New England Journal of Medicine found that early surgery can reduce death rates from aortic aneurysms by 90% compared to emergency repairs. The study involved 675 Marfan syndrome patients and showed that mortality rates were significantly lower when treatment was initiated earlier.
A study of 270 patients with intracranial aneurysms found that diabetes increases the likelihood of posterior circulation aneurysms, while prior pregnancy is a risk factor for multiple aneurysms. The researchers hope to better detect and treat aneurysms in patients by identifying these risk factors.
The study found that the risk of rupture for small aneurysms (less than 10 mm) is low, especially in patients without a history of subarachnoid hemorrhage. The investigators advise against surgery for most patients with small aneurysms and no history of brain hemorrhage, suggesting monitoring as an alternative.
A new international study has identified that small intracranial aneurysms have a very low probability of rupture if the patient has no history of ruptured aneurysms. Patients with these conditions can live a normal lifestyle with minimal risk while monitoring their aneurysm.
Researchers at Thomas Jefferson University have developed a method to reverse dangerous cerebral vasospasms. The treatment involves administering a drug that dilates cerebral blood vessels, reversing constricting effects within 30 minutes.
A study published in the Journal of Neurosurgery found a significant link between smoking and cerebral blood-vessel damage. Smokers are nearly five times more likely to develop vasospasm, a violent constriction of arterial walls that can lead to stroke-like symptoms.
A recent Cleveland Clinic study found a three-fold increase in gelatinase activity among patients with brain aneurysms, weakening the structural proteins in brain arteries. This discovery could lead to the development of a predictive test and preventive therapy for aneurysm formation.