Researchers found that high weight prior to diagnosis was associated with poorer survival, particularly in women who had never smoked. Weight gain after diagnosis also increased the risk of recurrence and death, especially among normal-weight women.
A review of nutritional modalities for treating epilepsy suggests that diets high in fat and polyunsaturated fatty acids may be effective in controlling seizures. The Atkins diet has shown promise as an easier-to-follow alternative to the ketogenic diet, although its success depends on implementation.
Scientists developed a high-pressure photoelectron spectroscopy system to study chemical underpinnings of everyday catalytic, biological, and ecological phenomena. They found that negatively charged ions concentrate at the surface of salt grains as they dissolve in water.
A Johns Hopkins Medicine study found that pilots with a DWI history have a 43% higher crash risk than their counterparts without one. The researchers analyzed over 300,000 pilots and tracked their flying records, concluding that background checks can effectively predict and prevent crashes.
Researchers at New York University have discovered over 150 additional genes required to make an embryo, bringing the total estimated number of genes needed to around 2,600. The study also sheds light on how these genes work in humans and provides clues for understanding human diseases.
The report lists 58 substances as 'known human carcinogens' due to evidence from human studies, including HBV, HCV, and HPV. Eleven new substances have been added to the list of 'reasonably anticipated human carcinogens', including naphthalene, MeIQx, and lead.
A study published in PLOS Biology found that E. coli bacteria, which reproduce symmetrically, have a reduced growth rate, decreased offspring formation, and increased risk of dying compared to cells inheriting new poles.
A study published in Pacing and Clinical Electrophysiology journal confirms catheter ablation is safe for patients, with no significant damage to cardiac nerves. The procedure is now a standard therapy for various arrhythmias, including SVT, atrial fibrillation, and AV nodal re-entrant tachycardia.
Chemists in Australia have created a molecule called the 'superbowl' that can carry large molecules of medicinal value, including painkillers and chemotherapy drugs, to specific areas of the body. The molecule shows promise for precision drug delivery and may one day improve medical treatments and save lives.
A team of scientists has published a near-complete genome analysis of rice, revealing a whole-genome duplication event that may have played a role in the origin of grasses. The study provides important insights into the evolution of rice and its possible impact on human history.
The new privacy rule has reduced biomedical research recruitment to an average of 2.5 to 5.7 women per week, significantly impacting the field's progress in understanding preeclampsia and its devastating effects on pregnant women. Dr. Ness calls for modifications to the rule itself to standardize institutions' interpretation.
Researchers at the University of Houston discovered a zebrafish that glows in response to light, shedding light on biological clocks. The per3-luc zebrafish contains genetic material that enables its circadian rhythm without parental influence.
A study published in the Journal of Thrombosis and Haemostasis found that moderate amounts of alcohol can reduce cardiovascular risk in women, particularly those who are postmenopausal. The research suggests that low to moderate wine consumption may have a favorable effect on cardiovascular events in this demographic.
A study of 3,107 older adults found that screening for osteoporosis using a bone density test reduced the incidence of hip fractures by 36% compared to usual medical care. The study provides new evidence for the effectiveness of osteoporosis screening in preventing fractures.
A meta-analysis of 156 studies found that heavy alcohol drinking is strongly associated with an increased risk of primary liver cancer, breast cancer, large bowel cancer, and other related diseases. The risks are shown to increase with the amount of alcohol consumed, but no threshold below which no effect is evident.
Scientists at Northwestern University have developed a new diagnostic test for Alzheimer's disease using bio-bar-code amplification technology. The test can detect miniscule amounts of a toxic protein in human cerebrospinal fluid, which may be responsible for early neurological deterioration.
Researchers uncover key mechanisms behind puberty, revealing that a specific gene and protein interact to trigger hormone secretion. The study provides new insights into human development and may help prevent precocious or delayed puberty.
Researchers at MCG Medical Center are studying a bioartificial kidney that can mimic the functions of natural kidneys, reducing mortality rates in ICU patients. The device, developed by Dr. H. David Humes, uses billions of donor kidney cells to filter waste and regulate various bodily processes.
Researchers found that treatment with Viagra increases therapeutic levels of nitric oxide in heart cells, stabilizing mitochondria and reducing cell death. This may lead to new treatments for patients with heart failure where loss of cells is primarily due to apoptosis.
Researchers at Duke University Medical Center discovered that an inability of red blood cells to relax blood vessels through the release of nitric oxide is a major factor behind sickle cell disease symptoms. Restoring nitric oxide to blood cells may serve as a useful method for treating the disease.
Researchers developed a model linking Huntington's disease mutation to cell death, revealing calcium signaling as a key defect. A new drug, enoxaparin, prevented inappropriate calcium release and cell death in mouse neurons carrying the mutant huntingtin gene.
The AAAS has selected five science reporters from Africa to receive fellowships and training at the 2005 Annual Meeting. The program aims to encourage outstanding young science journalists and support their coverage of science and health topics in developing countries.
A Canadian Medical Association Journal article evaluates the economic impact of sirolimus-eluting stents, finding they are cost-effective in high-risk patients. However, their use is associated with a similar or higher cost per quality-adjusted life-year compared to other medical treatments.
UCI's undergraduate research programs will receive a $900,000 funding boost from the National Science Foundation and National Institutes of Health. The programs, launching this summer, will allow students to conduct interdisciplinary research in biomedical and health promotion fields.
Researchers analyzed Al-Sayyid Bedouin Sign Language (ABSL), a community of 3,500 deaf and hearing people, revealing a distinct grammatical structure that establishes systematic relations among words. ABSL follows a Subject-Object-Verb order, differing from English and other languages in the region.
At least 33% of patients with congestive heart failure who receive specialized pacemakers fail to respond, highlighting the need for more research in selecting candidates. This study suggests that traditional pacemaker implantation may not be effective for patients with previous heart attacks.
The American College of Physicians recommends one-time ultrasound examination for abdominal aortic aneurysm screening in men aged 65-75 who are smokers. New evidence suggests that large abdominal aneurysms may reduce deaths from ruptured aneurysms. Meanwhile, a study found that the COX-2 inhibitor rofecoxib increases heart attack risk ...
Researchers have created a new tool to investigate the components of the circadian clock in vertebrates using transgenic zebrafish that luminesce in sync with their periodicity. The study reveals that aspects of circadian rhythms develop in specific stages, rather than being hardwired into the embryo.
Researchers found that deleting pro-inflammatory enzyme IkB kinase â (Ikk-â) from immune cells' macrophages improves insulin sensitivity, offering hope for new type II diabetes treatments. The study suggests targeting myeloid cells and their macrophages as a potential strategy for treating the disease.
Researchers at Duke University Medical Center have identified a gene defect that causes Charcot-Marie-Tooth disease, a prevalent and inherited nerve disorder. The discovery provides new insights into the nervous system and may lead to the development of targeted therapies for this debilitating disease.
Researchers discover viral DNA sequence in MMTV Env protein that transforms mouse breast cells. The study suggests a potential new mechanism for virus-induced breast cell transformation.
Researchers have developed a new fluorine-18 labeled imaging agent, nifrolidine, which binds to a receptor involved in cognition and learning. This receptor is also linked to nicotine addiction and lung cancer, making it a potential target for early Alzheimer's disease diagnosis and treatment.
Researchers create a new mathematical model that explains the relationship between friction and motion, suggesting that traditional braking methods may not be the most effective. The findings could lead to improved road safety by optimizing brake performance.
Researchers have devised a thermometer that can measure granular temperature based on the degree of agitation of its component particles. The discovery could lead to better understanding of powders and particulate materials in industries such as pharmaceuticals, food processing, and construction.
A new study found that the transcription factor c-Myb regulates hematopoiesis at multiple points, controlling HSC self-renewal and proliferation. This breakthrough has significant implications for developing compounds to regulate stem cell fate decisions, a potential game-changer for stem cell therapy.
A recent study sheds light on the disparities in pain care faced by minority groups, including African Americans and Hispanics. The research reveals that these individuals often receive inadequate pain management, contributing to worse health outcomes.
Substances in wine have been shown to share the characteristics of ethanol, preventing blood clotting and providing cardio-protective effects. Additionally, wine has been found to reduce mortality from cancer compared to other alcoholic beverages, thanks to its antioxidant properties.
Scientists at UCSB study the relationship between recent severe storms and increased oil emissions from the Coal Oil Point seep field. Researchers estimate current oil emissions are many times pre-storm levels, with new areas of seepage appearing and gas driving the flow.
A study of 25 northern British Columbia women reveals three key coping mechanisms: becoming hardy, making the best of the North and supplementing it. These strategies involve self-reliance, spiritual beliefs, outdoor activities and social support networks.
A new nanoscale diagnostic technique has been developed to detect possible traces of Alzheimer's disease in cerebrospinal fluid. The procedure uses magnetic and DNA particles to identify biomarkers, which could lead to early diagnosis and effective treatment if proven successful.
Research suggests that erectile dysfunction (ED) is a significant public health concern associated with cardiovascular medicine. Early recognition of ED in high-risk populations can lead to early diagnosis of cardiovascular risk factors and subclinical vascular disease.
Researchers propose a new naming system for bird neurosystems, revealing similarities to mammalian brains. The revised nomenclature reflects recent discoveries in neural processing and behavior, highlighting the cognitive abilities of birds comparable to those of mammals.
Researchers estimate that progesterone therapy could reduce the rate of recurrent preterm birth in the US by about 2%, preventing around 10,000 premature births annually. The study's findings are based on a clinical trial showing a significant reduction in preterm birth risk among women with a history of spontaneous preterm birth.
Researchers at the University at Buffalo are conducting a 12-week study to evaluate the effectiveness of an amino acid supplement in reducing hot flashes in postmenopausal women. The trial will compare the active treatment with a placebo, and results may offer an alternative to hormone replacement therapy.
The ASBMB-Avanti award recognizes Dr. Dowhan's work on lipid-protein interactions, which has expanded our understanding of lipids' roles in cellular processes. His research has established the molecular basis for new lipid functions and impacts a wide range of investigators.
Researchers have successfully measured the back-flow effect in Brownian motion, a phenomenon Einstein predicted but overlooked 100 years ago. The discovery uses optical tweezers technology to detect this effect, confirming a key aspect of Brownian motion theory.
Researchers found that chaos and noise are essential for maintaining marine ecosystems, allowing plankton blooms to flourish even in suboptimal conditions. By adding noise to a system, it can become synchronized and sustained, contrary to previous assumptions.
Researchers found that excessive build-up of succinic acid in mitochondria triggers a sequence of events leading to tumour growth. The study increases understanding of molecular basis of several types of cancer, crucial for developing new prevention, diagnosis and treatment methods.
A randomized controlled trial found that amoxicillin was more effective than placebo in treating middle ear infections in children, but showed no significant difference in adverse events or recurrence rates. The study suggests that antibiotics may be a useful treatment option for this common childhood illness.