Articles tagged with Aneurysms
Researchers confirmed a genetic variant linked to significantly increased risk of aortic dissection or full rupture. Patients with the mutation may benefit from earlier surgical therapy before an aortic dissection occurs.
A new study published in The Lancet found that US patients with ruptured abdominal aortic aneurysms have higher survival rates compared to English NHS patients. The research reveals that American hospitals offer more surgical treatments, resulting in 13% fewer deaths, whereas English hospitals were less likely to perform such procedures.
Researchers at UC San Diego have found that the health risks to pregnant women with a history of Kawasaki disease (KD) are low with proper management and care. The study, published in British Journal of Obstetrics and Gynaecology, also notes that the long-term risk for adults with KD is not known.
A Kaiser Permanente study found that an EHR-based screening program for abdominal aortic aneurysms (AAAs) reduced the number of unscreened at-risk men by over 50% in 15 months. The program used electronic health records to signal providers that patients needed screening, leading to a significant decrease in unscreened patients.
A new multilayer stent may revolutionize the treatment of aortic aneurysms in the US, offering improved outcomes and reduced need for surgical bypass grafts. The device has already shown promising results in European trials, with patients experiencing similar or better outcomes than those treated with traditional stents.
Research using a mouse model of Loeys-Dietz syndrome reveals that enhanced TGF-beta signaling contributes to the development of aortic aneurysms. Treatment with Angiotensin II type 1 receptor antagonists shows promise in ameliorating aortic aneurysm progression.
Researchers discover embolic material, polyvinylpyrrolidone (PVP), at site of fatal brain hemorrhages occurring days after aneurysm treatment. PVP is suspected to have traveled through vasculature from PED delivery site to location where hemorrhage occurred.
A rare glimpse into President Taft's weight loss journey with a modern approach to treating obesity, and how lifestyle changes can prevent diabetes in high-risk patients. Unruptured brain aneurysms are common but few cause harm.
Researchers identify markers that can predict rupture in abdominal aortic aneurysms, including dense white blood cells and C-reactive protein levels. The study suggests that PET/CT scans with positive uptake could provide diagnostic support for surgery, while negative uptake may indicate safe avoidance of unnecessary procedures.
A telestroke service increased the rate of effective tissue plasminogen activator (tPA) therapy for patients with acute ischemic stroke treated at community hospitals. This improvement in care resulted from the use of remote presence technology, allowing stroke specialists to consult on patient care without specialized equipment.
Researchers identified a chemical compound that reduces vasospasm and allows oxygen-filled blood to flow into the brain. The study found that the compound keeps glutamate 'in check,' preventing dangerous constriction of blood vessels.
A Finnish population-based study found that hypertensive smoking women have an exceptionally high risk of a fatal brain bleeding, with a rate 20 times higher than never-smoking men. The study identified new risk factors for Subarachnoid Haemorrhage (SAH), including previous myocardial infarction and elevated cholesterol levels in men.
A study published in Neurosurgery found that bone morphogenetic protein (BMP) increases the risk of benign tumors, particularly those affecting the nervous system. In contrast, BMP has no association with an increased risk of malignant cancers.
A new UCLA study finds that brain aneurysms of any size can grow and increase the risk of rupture. Tobacco smoking and larger initial aneurysm size are also linked to growth and higher rupture risks.
A study found that cerebral aneurysms of all sizes are 12 times more likely to rupture if they grow in size. The researchers observed growth in nearly 18% of asymptomatic cerebral aneurysms and found a strong association between aneurysm growth, initial size, and tobacco smoking.
Revascularization procedures have reduced the need for amputations in peripheral arterial disease patients by 40% over two decades, according to Mayo Clinic research. The study analyzed patients with leg pain and found that as use of revascularization rose, the amputation rate dropped.
Researchers found a 'weekday effect' in mortality rates for patients undergoing elective surgery, with higher risks at the weekend and end of working week. The study suggests poorer quality of care may contribute to this, particularly for patients with more diseases or previous admissions.
Researchers at UCLA successfully treated two patients with severe ventricular arrhythmias using a minimally invasive technique normally employed in treating brain aneurysms. The coil embolization procedure helped stop the electrical storms and eliminate the blood supply to the affected area, allowing the heart to return to normal rhythm.
Surviving patients with ruptured aneurysms have persistent problems in key areas affecting quality of life, including mobility and anxiety/depression. Long-term follow-up care plans are necessary to address these challenges.
For most patients with small aneurysms, surveillance intervals can be extended, reducing the number of scans from 15 to 7 per year, without significantly increasing rupture risk. The study found that men's rupture risk increased by a factor of 1.9 for every 0.5-cm increase in baseline AAA diameter.
A recent study published in Neurosurgery found that pregnancy and delivery do not increase the risk of brain aneurysm rupture. In fact, women with unruptured aneurysms have a high rate of cesarean deliveries, which may be unnecessary. The study also suggests that prompt treatment after rupture can help decrease poor outcomes.
Researchers confirm the value of the Pipeline embolization device in treating difficult-to-reach brain aneurysms. The study showed that the device is a safe and effective tool for patients, with 68% achieving complete occlusion of their aneurysm.
A research team led by Professor Zamaneh Kassiri has discovered that boosting TIMP3 levels can prevent the development of abdominal aneurysms. The study found that a protein called MMP2, despite being a contributor to heart and vascular disease, did not cause aneurysms when combined with TIMP3 deficiency.
A new study led by Johns Hopkins Medicine found that long-term survival rates for patients undergoing abdominal aneurysm repair with either open or less-invasive endovascular procedures are comparable. However, the research suggests that elderly patients may not benefit from the minimally invasive operation.
The Pipeline embolization device shows encouraging results in patients with certain types of difficult-to-treat brain aneurysms, including a 68% complete blockage rate. However, the data also show substantial risks, including major complications and fatal bleeding, particularly for aneurysms in specific locations.
A Mayo Clinic study found that endovascular repair has a low rate of complications, even in high-risk patients. Researchers analyzed data from 1,008 consecutive patients and found a lower mortality rate than open-abdominal surgery when aneurysms ruptured.
A new study found that the endovascular technique for repairing ruptured abdominal aortic aneurysms does not conclusively improve survival rates. The study, published in the Journal of Vascular Surgery, compared outcomes between patients who underwent emergency endovascular surgery and those who had open surgery.
Researchers from UTHealth and France have discovered a gene defect linked to systemic complications including life-threatening thoracic aortic disease and intracranial aneurysms. The new syndrome is similar to Marfan and Loeys-Dietz syndromes but distinct in its genetic cause.
A patient registry has yielded crucial data on the clinical features and outcomes of fibromuscular dysplasia (FMD), a non-inflammatory vascular disease. The study found that 91% of patients are women diagnosed in their prime of life, with an average delay in diagnosis of four years from symptom onset.
Research published online first in the Journal of NeuroInterventional Surgery found a link between early menopause and an increased risk of cerebral aneurysms. Women who entered menopause at a younger age were more likely to develop brain aneurysms, while later menopause and hormone replacement therapy reduced the risk.
Specialized care from experienced teams reduces the chance of immediate death and disability by 30% for patients with bleeding brain aneurysms. Patients who receive this treatment have better long-term survival and quality of life.
A new study found that contrast-enhanced ultrasound is a highly effective method for monitoring patients after endovascular repair for abdominal aortic aneurysms. The technique offers real-time exploration without ionizing radiation or kidney damage, supporting its integration in EVAR follow-up.
Researchers found carotid endarterectomy to be a safe, less expensive treatment option for certain patients at risk for stroke. Mayo Clinic neurosurgeons also present findings on intracranial dural arteriovenous fistulas and giant aneurysms using flow diversion.
A minimally invasive interventional radiology treatment called endovascular aortic repair is associated with lower mortality rates and shorter hospital stays compared to open surgical repair for ruptured aneurysms. The study found that women had worse outcomes after the procedure, highlighting the need for further research in this area.
Two tiny molecules, miR-21 and miR-29b, have been found to strengthen the aorta during bulge growth, reducing abdominal aortic aneurysms in mice. The team believes this could lead to a new treatment for the disease.
Researchers identified 27 genetic variants in 19 genes associated with brain aneurysms, including collagen 5-A2 linked to Ehlers-Danlos syndrome. Whole exome sequencing allowed for targeted screening of affected families, offering potential for personalized risk assessment and prevention strategies.
The experimental drug clazosentan reduced the risk of blood vessel spasm in patients with a brain aneurysm. Patients on higher doses of the drug experienced a significant reduction in vasospasm-related complications, including neurological deficits and respiratory issues.
Outcomes for unruptured brain aneurysms treatment have remained stagnant over the last 10 years, attributed to minimally invasive endoscopic coiling procedures at lower-volume community hospitals. These procedures lead to inferior outcomes and increased technical shortcomings or errors in judgment.
A team of researchers found that brown fat in adult men burns energy to generate body heat when exposed to cold temperatures, but not at warm temperatures. This discovery has significant implications for the human obesity epidemic, suggesting that increasing brown fat is unlikely to lead to weight loss and instead highlights the need f...
UBC researchers have created a monitoring technique for brain aneurysms using platinum implants as antennas to detect blood levels and indicate implant failure. This approach may enable patients to check their condition at home, reducing the need for invasive procedures.
A new study has identified that using less invasive spinal, epidural, and local/monitored anesthesia care is better than general anesthesia for elective endovascular repair of infrarenal abdominal aortic aneurysms. This results in reduced pulmonary complications and shorter hospital stays.
A comprehensive analysis of medical outcomes research found that few brain aneurysm patients receive specialized care at high-volume stroke centers. Patients who receive care in experienced centers are more likely to have definitive repair and good recovery.
A study found that patients with BAV have an increased risk of aortic dissection, with a 8.4 times higher risk compared to the general population. The 25-year risk of aortic surgery was also high, at 53%. The researchers highlight the importance of close monitoring and early recognition for prevention.
A new study by UTHealth and BCM researchers identified a common genetic variant associated with an increased risk of thoracic aortic aneurysms and acute aortic dissections. The variant, located on chromosome 15q21.1, involves the FBN1 gene, which is also linked to Marfan syndrome.
A study by Johns Hopkins physicians found that stents can prevent brain aneurysms from recurring after minimally invasive coiling procedures. The research suggests that stenting can make coiling a more promising option for the 30,000 people diagnosed with brain aneurysms each year in the US.
Researchers are working on developing new treatments for brain aneurysms using gel-based delivery systems and mathematical modeling. The goal is to prevent the growth of aneurysms and improve cardiovascular health outcomes, ultimately reducing mortality rates from heart disease and stroke.
A study found that people with duplications in chromosome 16's 16p13.1 region are at 12-fold increased risk of thoracic aortic aneurysms and dissections. Researchers from UTHealth and Baylor College of Medicine discovered this association, which may lead to aggressive forms of the disease and require closer monitoring.
Research published in the Journal of NeuroInterventional Surgery suggests that taking oral contraceptives or hormone replacement therapy may reduce the risk of developing cerebral aneurysms. The study found that women with cerebral aneurysms were less likely to have taken these medications and had an earlier average age of menopause.
New study provides clearer picture of cellular signals contributing to aortic aneurysm progression in Marfan syndrome. Losartan alters these signals by blocking TGF-beta's partner, angiotensin II receptor.
Researchers at Johns Hopkins Medicine have made significant progress in understanding the mechanisms behind losartan's protective effects against life-threatening aortic aneurysms in patients with Marfan syndrome. By identifying key proteins involved in the disease process, the team has found new targets for potential treatments.
A University of Cincinnati researcher won a prestigious award for his study on familial intracranial aneurysms and their genetic connection. The research found that concordance in the location of aneurysms within families was higher than between families, suggesting a heritable component to anatomic vulnerability.
Researchers identify 47 copy-number variant regions associated with sporadic and familial aortic aneurysms (TAAD), highlighting disrupted smooth muscle function as key mechanism. The findings have significant implications for other adult-onset cardiovascular disorders, suggesting potential targets for screening and prevention.
Researchers discovered that asthma drugs can block cysteinyl-leukotrienes, reducing vessel wall breakdown and dilation. This could lead to the development of new treatments for aortic aneurysms, potentially saving lives and reducing surgical complications.
A new study suggests that oral contraceptives and hormone replacement therapy may reduce the incidence of brain aneurysms in women. The study, conducted at Rush University Medical Center, found strong similarities between women with unruptured and ruptured aneurysms, including lower estrogen levels.
Radiologists must consider the diagnostic value of multiplanar reconstructions to accurately diagnose superior mesenteric artery aneurysms. Contrast administration can help distinguish aneurysms from pancreatic masses, which may have similar density or intensity signals on unenhanced CT scans and MRI.
A new study published in Neurology shows that people with a common heart defect called bicuspid aortic valve (BAV) are more likely to develop brain aneurysms. The research found that 9.8% of individuals with BAV had brain aneurysms, compared to 1.1% of those without the condition.
Researchers identified KLF15 as a genetic factor regulating both heart failure and aneurysm disease. The study found that deficiency of this gene predisposes individuals to these cardiovascular diseases, but also discovered potential therapeutic targets through the inhibition of p53.
A Yale-led team has discovered three new genetic factors that significantly increase the risk of developing brain aneurysms. The study analyzed over 20,000 subjects and found that individuals carrying these variants are up to seven times more likely to suffer an aneurysm than those with no risk factors.
A new study reveals that the utilization of minimally invasive aneurysm repair varies by region due to patient risk factors and physician experience. The study found a strong correlation between higher-risk patient populations and physicians more experienced in treating aneurysms.
Researchers found that smoking significantly increases the risk of an intracranial aneurysm in people who carry common gene variants. The risk increased by more than five-fold when combined with smoking, highlighting the importance of quitting to reduce genetic susceptibility.