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Efficacy, pharmacokinetics, and safety of nebulized HL231 inhalation solution in patients with chronic obstructive pulmonary disease: a randomized trial

The study demonstrated that nebulized HL231 at 261 µg/141 µg dose achieved comparable bronchodilation efficacy, pharmacokinetic profiles, and safety outcomes to Ultibro. HL231 showed a clear dose-response relationship with predominantly mild-to-moderate adverse events.

SourceNational Center for Respiratory Medicine·JournalJournal of Thoracic Disease·DateNov 9, 2025

Phenotypes and endotypes in bronchiectasis: a narrative review of progress toward precision medicine

This article reviews bronchiectasis phenotypes and endotypes, exploring their impact on disease management and treatment strategies. Recent research has identified distinct inflammatory endotypes, guiding targeted therapies and improving patient outcomes through personalized approaches.

SourceNational Center for Respiratory Medicine·JournalJournal of Thoracic Disease·TypeLiterature review·DateJul 30, 2025

Chinese Medical Journal Pulmonary and Critical Care Medicine study uncovers trends in the global burden of tracheal, bronchus, and lung cancer

The study found a decreasing trend in the global TBL cancer burden from 1990 to 2019, but regional variations persisted. The burden was highest in upper-middle-income countries and lowest in high-income countries.

SourceCactus Communications·JournalChinese Medical Journal - Pulmonary and Critical Care Medicine·TypeData/statistical analysis·DateJun 22, 2023

Gators breathe like birds

Researchers found that air flows in one direction through alligators' lungs, a trait shared with birds. This unidirectional airflow may have helped archosaurs dominate Earth after the Permian-Triassic extinction, which wiped out 70% of land life.

SourceUniversity of Utah·JournalScience·DateJan 14, 2010