A new study finds that exposure and response prevention (EX/RP) therapy for OCD improves cognitive control by strengthening connections between brain networks. This breakthrough sheds light on the mechanisms underlying EX/RP's effectiveness in treating OCD, paving the way for targeted therapies.
The Human Brain Project has achieved remarkable progress, delivering an open research infrastructure that will have a transformative impact in Europe and beyond. The project's legacy can be seen in its leading digital brain atlases, advanced brain simulation platforms, and outstanding advances in neuromorphic computing and AI.
Researchers have discovered a bidirectional interaction between amyloid-beta protein and sulfatides that may play a key role in the development of Alzheimer
Research found that higher cortical excitability is recorded during the systolic phase of the cardiac cycle, suggesting a link between heartbeats and neural processing. This study has implications for treatments of depression and stroke, where TMS pulses stimulate nerve cells.
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A Virginia Tech scientist has identified a molecule in the hypothalamus region of the brain linked to stress-induced emotional overeating. The discovery may lead to new therapy targets for alleviating emotionally triggered eating.
The ultra-high resolution NexGen 7T scanner allows neuroscientists to see functional MRI features 0.4 millimeters across, enabling the study of brain circuitry underlying different diseases with higher spatial resolution. This will help track signals propagating through the brain and reveal underlying causes of developmental disorders.
A study by the University of Ottawa found that various long-term memory types, such as semantic and episodic memory, rely on the same brain network to varying degrees. The research used neuroimaging techniques to compare brain activity across different memory conditions.
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Researchers argue that the brain does not create new functions in previously unrelated areas but instead utilizes existing latent capacities. They provide alternative explanations for observed changes in brain activity following injury or deficit.
Researchers found that babies as young as four months old display enhanced somatosensory brain activity when a touch is preceded by an object moving towards them. This suggests that even in the first few months of life, babies can sense their surroundings and understand how their bodies interact with space.
Scientists studied how players' brains react when working together in a computer game called Pacman. They found that the brain's response is linked to the player's role during cooperation.
A novel AI system analyzing brain MRI scans can diagnose autism in children between 24 and 48 months with a 98.5% accuracy rate. This technology enables early detection of autism, potentially leading to improved independence, IQs, and therapeutic outcomes.
UTEP researchers develop a therapy based on caffeic-acid derived from spent coffee grounds to protect brain cells from damage. The treatment has potential to prevent neurodegenerative disorders such as Alzheimer's and Parkinson's by removing free radicals and inhibiting amyloid protein aggregation.
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A study published at the Radiological Society of North America annual meeting found that higher amounts of visceral abdominal fat in midlife are associated with increased risk of Alzheimer's disease. The research also showed that this type of fat is linked to brain inflammation, which may contribute to the development of the disease.
Researchers created an AI system with physical constraints to develop brain-like features, such as hubs and flexible coding schemes. The system solved a maze navigation task by combining multiple pieces of information, similar to human brains. This study sheds light on how physical constraints shape differences in brain organization.
Researchers at University of Pittsburgh and KU Leuven identified 30 genetic regions associated with head shape, shedding light on the biological basis of craniosynostosis. The study also found that many genes play key roles in early head formation and bone development.
Researchers at the University of Wisconsin-Madison have successfully generated human norepinephrine neurons from stem cells using a key protein called ACTIVIN-A. These LC-NE neurons may serve as models for disease in humans, enabling scientists to screen drugs and answer questions about neurodegeneration.
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A review of 23 years of neuroimaging research finds that screen time affects the pre-frontal cortex and other brain regions involved in executive functions, memory, and processing. Digital experiences may shape children's brains and influence cognitive development, with both positive and negative impacts.
Elea Abisamra's STEM writing program at Virginia Tech has been recognized by the journal Cell for its innovative approach to teaching science through storytelling. The program has already helped 95 kids publish books with over 150 tutors as editors, and plans to expand globally.
Multimodal neuromonitoring (MNM) tracks blood flow, pressure, oxygen and glucose levels in the brain to inform treatment decisions. MNM has improved clinical outcomes for patients with severe traumatic brain injuries at the University of Cincinnati.
A new study reveals that exposure to ultrafine particles from traffic alters the expression of many genes in human olfactory mucosa cells. The study found that different fuels and engines cause distinct effects on cell function, with renewable diesel causing less adverse effects than fossil diesel.
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Scientists have found that microglia play a crucial role in regulating the number of cells that become neurons in the brain, enhancing our understanding of brain development and disorders. The discovery also reveals a unique pathway through which microglia interact with other brain cells, involving cholesterol transfer.
A new study found that neuroinflammation is a key feature of the brain response to blast exposure, affecting regions associated with memory retrieval, executive functioning, and sensory processing. Increased blast exposure also relates to reductions in volume and thickness of brain structures.
Research suggests that global warming can affect brain development and plasticity, as well as lead to changes in cognitive function and overall health. The study calls for further investigation into the impact of extreme weather events on brain structure and behavior.
A recent study published in the Proceedings of the National Academy of Sciences found that AI's deep convolutional neural networks can identify faces but struggle to capture other important information like emotional state and trustworthiness. Brain activity scans revealed a weak correlation between AI's codes and human brain represent...
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A new study has identified a brain connectivity variate that predicts psychiatric disorders in adolescents. The finding provides evidence for a transdiagnostic brain-based measure underlying individual differences in developing psychiatric disorders in early adolescence.
The UTSA MATRIX AI Consortium has received a $2 million grant to create new AI models that rapidly learn, adapt, and operate in uncertain conditions. The team aims to bridge the gap between human brain processing efficiency and current AI limitations, enabling more efficient and adaptive AI systems.
A new USC study reveals that variants of the autism-linked gene SYNGAP1 can disrupt early brain development in the cortex, a region involved in higher-order cognitive functions. The research found that disease-causing variants of SYNGAP1 alter the cells' cytoskeletons and lead to disorganized neural circuits.
Researchers found that the brain can distinguish between human error and non-error outcomes in as little as 1,000 milliseconds. In cases of human error, the brain takes additional time to catalog the mistake and inform the body to avoid repeating it.
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A longitudinal study found that nine-to-10-year-old children who drink daily caffeinated soda are twice as likely to try alcohol within a year. Daily caffeine intake is associated with low working memory and high impulsivity, recognized risk factors for substance use disorders.
Researchers at Trinity College Dublin discovered that autism-induced maternal immune response alters brain development and prevents infantile amnesia. Memories formed during infancy can be permanently reinstated through light-activated neural pathways in adults.
Regular cannabis users show a greater understanding of others' emotions, while their brains exhibit stronger connections between regions related to emotional sensing. This study suggests potential therapeutic applications for conditions involving social interaction deficits.
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Two new studies by experts at Georgia State University's TReNDS Center highlight the potential of brain imaging to identify biomarkers for cognitive developments and psychiatric issues in adolescent brains. The research team analyzed functional network connectivity across scans and found associations with various health measures, inclu...
A study found that women using oral contraceptives had a thinner ventromedial prefrontal cortex than men, which is thought to sustain emotion regulation. The effects of COCs on brain development and emotional regulation are still not well understood, highlighting the need for further research.
Researchers found that changing treatment can lead to significant improvement in mobility and quality of life for patients with advanced Parkinson's disease. A nationwide registry is planned to develop scientifically sound guidelines for combination therapies.
A new speech prosthetic developed by Duke neuroscientists and engineers can translate brain signals into spoken words, improving communication for people with neurological disorders. The device achieved an accuracy rate of 40% in predicting intended speech from 90 seconds of brain activity.
Researchers at DZNE and Charité developed a novel treatment for autoimmune encephalitis by reprogramming white blood cells to target misdirected antibodies. The new therapy, called CAAR-T cells, has shown accuracy in laboratory studies and is planned for clinical trials.
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Researchers at Ohio State University will investigate the role of microglia cells in chronic inflammation and neuronal dysfunction after TBI, with a focus on preventing long-term consequences. The $7.7 million award aims to develop innovative healthcare solutions for traumatic brain injury survivors.
Greater PTSD symptoms were associated with higher carotid atherosclerosis and brain small vessel disease among midlife women. Women carrying the APOEɛ4 gene showed poorer cognitive performance in response to PTSD.
Scientists have discovered a genetic pathway between the heart and brain tied to fainting, suggesting that the heart sends signals back to the brain that can change its function. The study found that vagal sensory neurons play a key role in fainting, with their activation leading to rapid pupil dilation, suppressed heart-rate and breat...
A large brain autopsy study of women who experienced intimate partner violence found substantial vascular and white matter damage, but no evidence of chronic traumatic encephalopathy. The study also revealed significant medical comorbidity, including cardiovascular and cerebrovascular disease.
A recent study from Ohio State University Wexner Medical Center and colleagues found that Rumination-focused Cognitive Behavioral Therapy (RF-CBT) can reduce rumination in adolescents. The study also showed correlated shifts in brain connectivity, suggesting that RF-CBT can help young people break the painful mental loops that contribu...
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Research from the University of East Anglia found that children who are too short for their age can suffer reduced cognitive ability due to differences in brain function as early as six months. The study discovered a link between stunted growth and disrupted visual working memory, making them more easily distracted.
A brain-computer interface (BCI) has been successfully used to restore control of home devices for a patient with ALS, allowing the individual to navigate a communication board and smart devices without recalibration. The BCI device was implanted on the surface of the brain areas responsible for speech and upper limb function, enabling...
Researchers found that people with cocaine addiction have weaker signals when receiving rewards, disrupting the brain's ability to learn from experiences. This dysregulation is linked to reduced activity in the ventral striatum and orbitofrontal cortex.
Researchers found that neural signaling during online exchanges was substantially suppressed compared to face-to-face conversations. The study used imaging tools to track brain activity in real-time, revealing increased coordination of neural activity and enhanced face processing ability during in-person interactions.
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A new study from UTHealth Houston has found that the posterior temporal cortex and inferior frontal cortex are crucial for semantic integration during reading. This discovery may help illuminate the inner dynamics of aphasia, a disorder affecting language expression and comprehension.
Researchers at King's College London are studying the effects of maternal prenatal exposure to COVID-19 infection on children's brain development. The six-year study will explore how the maternal immune system affects fetal brain development and identify potential impacts on childhood outcomes.
An international team recorded real-time chemical activity in the human brain using clinical electrodes, providing insights into the brain's chemistry and its implications for various medical conditions. The groundbreaking methodology has opened a window to never-before-seen brain activity.
The WVU School of Medicine and Benjamin M. Statler College of Engineering and Mineral Resources will support clinical trials and engineering technology development. The project aims to improve care and rehabilitation for people with neurological disorders through novel physician-engineer programs and human research.
Researchers found that hierarchical cortical organization is impaired in people with schizophrenia, leading to disruptions in processing stimuli from the external world. This disruption affects secondary processing of sensorimotor-visual gradients, explaining behavioral and clinical symptoms of the disease.
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The 3rd annual Frontera User Meeting showcased the power of the NSF-funded supercomputer in various domains of science. Researchers presented findings on projects utilizing Frontera's capabilities, including compound storm surge models and nonlinear earthquake simulations. Additionally, scientists leveraged the system to analyze anonym...
Researchers developed a nanotechnology method to deliver medication through the blood-brain barrier, overcoming its selectivity and expanding therapeutic options for glioblastoma treatment. The technique demonstrated improved tumor shrinkage and survival rates in mice, paving the way for further preclinical studies.
Researchers found that deep neural networks often respond the same way to images with no resemblance to the target, generating unnatural signals. The models develop unique invariances that are different from human perceptual systems, causing them to perceive pairs of stimuli as similar despite their differences.
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Researchers created the first 'multiome' atlas of brain cell development in the human cerebral cortex, revealing specific changes in chromatin structure that precede gene expression. The study pinpointed regions associated with genes linked to neuropsychiatric disorders like schizophrenia and bipolar disorder.
Researchers developed a neural network model to accelerate detection of brain rhythms, reducing feedback signal delay from 500ms to 10ms. The approach shows promise for treating attention deficit disorder and epilepsy.
A massive research consortium has created the largest human brain cell atlases to date, revealing over 3,000 different kinds of brain cells. This breakthrough study provides new insights into the cellular organization of the human brain and its modular, functional nature.
Researchers have created detailed cell maps of the human brain and nonhuman primate brain, paving the way for new generation of treatments for mental disorders. The study reveals a comprehensive inventory of brain cells, their organization, and gene regulation, setting the stage for developing targeted therapies.
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Researchers assembled an atlas of hundreds of cell types that make up a human brain in unprecedented detail. The study uses techniques originally developed for mice to identify brain cell subtypes in human brains.
Researchers found that ordinary sleepers can pick up verbal information and respond to it by contracting facial muscles, even during most stages of sleep. The study suggests that standardized communication protocols may be possible with sleeping individuals to better understand mental activity changes during sleep.
Researchers mapped gene switches and brain cell types associated with various neuropsychiatric disorders, including schizophrenia and bipolar disorder. The study also developed AI tools to predict the influence of individual high-risk gene variants on disease.