Articles tagged with Parasites
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A clinical study has confirmed a single gene mutation as the cause of chloroquine-resistant malaria. The study developed a molecular marker that can diagnose individuals with chloroquine-resistant malaria, helping doctors select the best therapy and public health officials set country-wide treatment guidelines.
Researchers found a way to prevent infectious malaria particles from bursting out of their protective sacs by blocking the activity of a protein-snipping enzyme called protease. This discovery suggests that protease inhibitors could be used to treat malaria infection and keep the infectious particles imprisoned until they deteriorate.
Researchers identified a two-step process by which malaria parasites break out of red blood cells, paving the way for developing clinically useful inhibitors. The discovery may lead to promising targets for drug development and improved understanding of the disease.
Researchers have identified a single gene on chromosome 7 of Plasmodium falciparum that makes the most deadly malaria parasite resistant to chloroquine. The pfcrt gene is associated with chloroquine resistance in parasite lines from Asia, Africa, and South America.
Researchers have found a pore-like hole in the membranes of red blood cells infected by Plasmodium falciparum malaria parasite. This discovery may lead to new treatments for malaria, a devastating disease that kills over one million people each year. The study provides a new target for potential new malaria treatments.
Researchers have found pore-like holes in red blood cells infected by Plasmodium falciparum, a deadly form of the malaria parasite. This discovery may lead to the development of new treatments for malaria, a widespread and devastating disease that affects over 40% of the world's population.
A fatal tropical disease has infected large numbers of foxhounds in the US, causing skin lesions, hair loss, and joint issues. At least 12% of dogs have antibodies suggesting exposure to the parasite, with 2% showing a strong response, prompting public health officials to recommend quarantine or euthanasia.
Scientists have developed a fruit fly model to study malaria parasite development, which may lead to the creation of mosquitoes resistant to malaria. The research could also pave the way for better anti-malarial drugs and transmission-blocking vaccines.
Dr. Kisilevsky and his team aim to develop agents that prevent protein-carbohydrate binding, effectively inhibiting malaria parasite infection. The project builds on expertise gained in amyloid and Alzheimer's research, exploring novel ideas at a molecular level.
Researchers at University of Illinois find organelle with acidocalcisome properties, crucial for malaria parasite's existence, and propose using pyrophosphate analogs to target it. This discovery may lead to new treatment options against rapidly resistant malaria.
Scientists have discovered a potential drug target for treating African sleeping sickness by identifying a unique metabolic pathway in the parasite. The discovery offers hope for developing effective treatments for the estimated 500,000 people affected by the disease.
UW researchers find that oscillating magnetic fields can kill malaria parasites by damaging their iron-containing structures. The treatment could be inexpensive and simple, bypassing emerging drug resistance concerns.
Strepsipteran insects have eyes with larger lenses and more receptors, allowing them to sample 'chunks' of the visual field instead of points. This unique structure improves their visual capabilities and is similar to that of extinct arthropods like trilobites.
Researchers found that atovaquone was 100% effective in keeping volunteers bitten by mosquitoes carrying Plasmodium falciparum from developing the disease. Pairing atovaquone with proguanil, an older malaria-fighting drug, provides protection while avoiding drug resistance.
Two studies published in Science suggest that parasites, specifically Riberoria trematodes, are responsible for some frog deformities. Laboratory and field experiments found that parasite infections cause mirror-image limb deformities, distinct from the thigh-knee-thigh-knee pattern caused by retinoids.
Researchers are exploring transgenic mosquitoes capable of transmitting nitric oxide, which can kill parasites. This approach may offer a key to disrupting the complex relationship between mosquitoes and malaria parasites.
A veterinary parasitologist and his team have demonstrated that dogs are definitive hosts for Neospora caninum, a single-celled parasitic organism causing cattle abortions. This discovery has led to recommendations for improved cattle management strategies to reduce economic losses estimated at $35 million per year.
A University of Kentucky researcher has won a five-year extension on his MERIT award to study Leishmania donovani, a parasite that affects millions worldwide. The parasite, transmitted by sand flies, causes leishmaniasis, a disease often fatal and poorly treated.
Researchers found a striking increase in falciparum malaria in northern Honduras, with reported cases rising from 52,110 in 1994 to 75,565 in 1996. The more severe form of the disease accounted for 21% of infected patients, highlighting a significant public health concern.
Researchers discovered Cryptosporidium and Giardia parasites in 7.3% and 11.7% of stool samples from dogs, with puppies under 30 weeks old most affected. Despite no visible symptoms, these parasites can cause serious illness in humans.
Researchers have designed compounds that target Plasmodium falciparum parasites, which cause severe malaria. The new trioxane-based compounds show potential in treating the disease by inducing self-destruction in the parasite, offering a promising alternative to current treatments.
Research suggests that high levels of IgE type antibodies can cause an overactive immune response, leading to cerebral malaria. The study found a genetic link between IgE production and the production of TNF, which can be beneficial but also deadly in excessive amounts.
Scientists have discovered that two parasitic wasps, Spalangia endius and Spalangia nigoraenea, can efficiently control stable and house flies in Illinois. This finding has significant implications for the state's agricultural industry and public health.
Researchers at Johns Hopkins University have developed new chemical compounds that show promise in fighting malaria. The new compounds use the same mechanism to kill the parasite that causes malaria as another more expensive and difficult-to-produce drug, but are much less expensive and easier to produce.