Researchers developed a time-resolved cryo-ET method to capture snapshots of cultured neuronal synapses. The study identified a 'kiss-shrink-run' pathway that unifies the debated 'kiss-and-run' and 'full-collapse' fusion mechanisms, providing a structural basis for efficient synaptic transmission.
SourceShenzhen Institute of Advanced Technology, Chinese Academy of Sciences·JournalScience·TypeExperimental study·DateOct 23, 2025
Researchers at KAIST successfully clarified the three-dimensional, vortex-shaped polarization distribution inside ferroelectric nanoparticles using atomic electron tomography. This discovery has implications for ultra-high-density memory devices with capacities over 10,000 times greater than existing ones.
SourceThe Korea Advanced Institute of Science and Technology (KAIST)·JournalNature Communications·TypeExperimental study·DateMay 30, 2024
The São Paulo School of Advanced Science on Cryogenic Electron Microscopy will be held at the University of São Paulo from July 10-27, 2023. The event will cover theoretical and practical foundations of advanced CryoEM techniques, featuring renowned researchers and hands-on practical sessions.
SourceFundação de Amparo à Pesquisa do Estado de São Paulo·DateFeb 6, 2023
Researchers developed IsoNet, a software package solving intrinsic 'missing-wedge' problem and low signal-to-noise ratio issues in cryoET. IsoNet uses iterative self-supervised deep learning to perform missing-edge correction and denoise tomographic data.
SourceUniversity of Science and Technology of China·JournalNature Communications·DateNov 17, 2022
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Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.
Researchers used high-resolution micro-CT scans to reveal key features in Palaeospondylus fossils, placing it as an early ancestor of tetrapods. The study resolves long-standing evolutionary mysteries, including the lack of teeth and dermal bones in the fossil record.
Researchers from the Max Planck Institute have obtained the first high-resolution 3D image of the muscle protein nebulin using electron cryo-tomography. The structure reveals that each nebulin repeat binds with an actin subunit, acting as a ruler to dictate filament length and interacting with neighboring actin subunits to stabilize it.
SourceMax Planck Institute of Molecular Physiology·JournalScience·TypeExperimental study·DateFeb 18, 2022
A team of researchers has solved the structure of the HIV capsid alone and in complex with host factors using a novel approach. The breakthrough could lead to the development of capsid-targeting antivirals, providing new hope for those affected by HIV/AIDS.
SourceDiamond Light Source·JournalScience Advances·TypeImaging analysis·DateNov 19, 2021
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KAIST researchers have developed a deep learning approach to accurately determine the 3D surface atomic structure of nanoparticles. The method enhances precision by nearly 70% and improves surface atom identification, enabling the study of catalytic properties at the atomic scale.
SourceThe Korea Advanced Institute of Science and Technology (KAIST)·JournalNature Communications·DateMay 12, 2021
Scientists at Graz University of Technology have successfully imaged surface phonons in three dimensions, revealing the spatial distribution of electromagnetic fields near nanosurfaces. This breakthrough could lead to improved thermal conduction, sensor technology, and energy storage.
SourceGraz University of Technology·JournalScience·DateMar 29, 2021
Researchers at MIT and partners have created detailed 3D images of kerogen's internal structure, improving predictions of oil and gas recovery. The study reveals that mature kerogen has smaller pores connected by a network allowing for easier extraction.
SourceMassachusetts Institute of Technology·JournalProceedings of the National Academy of Sciences·DateNov 13, 2018
Researchers have developed a new transmission electron microscopy technique that can determine the 3D position of individual atoms with atomic resolution. The technique uses image intensity measurements to reconstruct the atomic potentials, allowing for more quantitative reconstruction of weakly scattering samples.
Researchers have developed a high-speed electron tomography technique that sets new standards for 3D imaging of the nanoworld. The method enables visualization of dynamic processes and structures with sub-nanometre precision, opening up new horizons in life sciences and soft matter research.
SourceForschungszentrum Juelich·JournalScientific Reports·DateOct 5, 2015
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Meta Quest 3 512GB enables immersive mission planning, terrain rehearsal, and interactive STEM demos with high-resolution mixed-reality experiences.
Researchers have made a significant breakthrough in understanding the microscopic electronic structure of cuprate superconductors, a key step towards achieving room-temperature superconductivity. The study reveals a stripe-like pattern in the static electron configuration, which differs from previous theoretical models.
SourceCanadian Light Source, Inc.·JournalScience·DateMar 19, 2015
Researchers at NIBIB have developed a new technique called BF STEM tomography, which allows for high-resolution 3D imaging of thicker specimen samples. This enables the visualization of larger internal structures in cells, providing greater insight into cell organization and function.
SourceNIH/National Institute of Biomedical Imaging & Bioengineering·DateSep 3, 2009
Researchers at Caltech used electron tomography to study the transport of antibodies from mother's milk to newborns' bloodstream. The findings revealed that antibodies are shuttled through large vesicles and form 'tangled messes' before being delivered into the bloodstream.
SourceCalifornia Institute of Technology·JournalNature·DateOct 10, 2008
The 3D-EM Network of Excellence aims to image macromolecules and molecular machines at atomic resolution, fostering innovation in European EM research. The network will provide training, a structural database, and user-friendly software to enhance structural analysis.
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