A research team has developed a reliable and economical method for studying proteins with sugar molecules attached to them in blood and tissue samples. The method uses commercially available magnetic particles and has the potential to aid in disease diagnosis and treatment.
The NIST/EPA/NIH EI Mass Spectral Library 2026 and NIST MS/MS Spectral Library 2026 are now available in various formats, providing expanded GC-MS and LC-MS coverage for laboratories to analyze mass spectra with high confidence. These libraries support evolving analytical workflow needs and deliver broader coverage and flexibility.
The 2026 release expands coverage of emerging novel psychoactive substances, including synthetic cannabinoids, fentanyl analogs, and pharmaceutical drugs. The database provides comprehensive and up-to-date support for forensic, toxicology, and drug surveillance workflows.
Wiley has expanded its spectral libraries with major updates to IR, Raman, and LC-MS collections, delivering researchers enhanced capabilities for faster and more confident compound identification. The expansion brings over 9.5 million high-quality spectra, including 1 million IR spectra and 161,000 Raman spectra.
ChromSolutions Ltd collaborates with Wiley to expand access to advanced untargeted analysis technologies for scientists in chromatography and spectroscopy. The partnership enables customers to benefit from more comprehensive tools for data analysis, enhancing productivity and confidence in complex samples.
Researchers developed a reliable and affordable purification technique for chromatography using calcium chloride, applying to organic compounds like amines and peptides. The technique has shown promising results in purifying APIs with high accuracy.
The new AEC-MS protocol provides comprehensive analysis of highly polar and ionic metabolites, improving molecular specificity and selectivity. This innovation has led to new applications in metabolomics, including studies on gut microbiome metabolism and energy substrate utilization.
An international team of researchers established standardized guidelines for analyzing oxylipins, bioactive lipids related to inflammation and disease. The guidelines aim to improve reproducibility in laboratories and facilitate the transfer of scientific discoveries to clinical practice.
The Wiley Registry has received a significant update with the addition of over 17,500 new spectra. The collection now boasts a total of 913,000 high-quality mass spectral data points. These updates enhance the database's comprehensive coverage and reliability, benefiting researchers in various fields.
Researchers at CNRS have discovered that chemical intermediates of the citric acid cycle can form spontaneously in interstellar ice. This finding suggests that the raw materials necessary for life could be present in space and potentially delivered to Earth.
SourceCNRS·JournalProceedings of the National Academy of Sciences·DateApr 21, 2025
Researchers developed a sustainable method of synthesizing diphenylmethanol derivatives using Chinese alumina, reducing waste and costs. The new method recycles alumina by washing it with water and drying between usages, making it an environmentally friendly alternative.
The study reveals that carbon storage in soil depends on the spatial distribution of pores, with a higher concentration of carbon found near pores. The researchers used X-ray CT to visualize pore systems and found that microbial activity decreases with increasing distance from the pores.
Researchers at the University of Copenhagen found hundreds of chemical substances in tap water stored in reusable plastic bottles, including some potentially harmful to human health. The study revealed that machine washing and dishwasher use can increase the leaching of toxic substances from the plastic.
Researchers discovered a new family of prenylated volatile sulfur compounds responsible for the characteristic skunky smell of cannabis. The findings suggest these compounds could have medicinal properties and are being investigated further.
Engineers from the University of Delaware develop procedure to purify monoclonal antibodies with 43% higher productivity, thanks to understanding of adsorption affinity and its role in protein transport into ion-exchange beads. This breakthrough could lead to reduced waste during expensive drug manufacturing process.
Researchers at RIT are refining lab-on-chip devices to analyze diseases faster and more cost-effectively. Blanca Lapizco-Encinas is improving the separation of biological cells and biomolecules using a combination of chromatography principles and dielectrophoresis.
Researchers at Berkeley Lab have developed a novel method to study the membranes of living cells by using size-based chromatography. This approach allows them to probe supramolecular structures in cell membranes at the nanometer length scales, providing insights into how spatial organization affects cellular function.
Researchers at Berkeley Lab have developed a portable system for highly sensitive multi-dimensional chemical analysis by pairing NMR/MRI technology with microfluidic chromatography. This breakthrough enables real-time peak detection and chemical shift information for small molecules, demonstrating the unique power of magnetic resonance...
Scientists at Rensselaer Polytechnic Institute used nuclear magnetic resonance (NMR) to understand and improve an important protein purification process. The study validated the effectiveness of multimodal chromatography, a method that separates proteins from their surrounding materials using molecular glue.
Yeung's contribution to the Humane Genome Project in the early 1990s helped turn it into a complete database in less than 10 years. He developed methods to miniaturize capillary electrophoresis, allowing for faster identification speeds and higher electric fields.
David Nelson, pioneer of chromatography data systems, recognized for promoting public understanding of analytical chemistry and its role in world economies. His work demonstrated the benefits of personal computers in analytical chemistry, benefiting forensic science, pharmaceutical drug discovery, and environmental remediation.