Articles tagged with Research Impact
Researchers at IU School of Medicine have discovered a critical gene mutation in the PLCG2 gene that heightens the risk of Alzheimer's disease. The study found specific rare variants that elevated or reduced the susceptibility to the disease, shedding light on the genetic underpinnings.
Researchers discovered that a small subpopulation of AIB1-expressing cells in breast cancer enables invasion and metastasis. The study suggests that these subpopulations play a crucial role in tumor growth and spreading to distant sites.
A comprehensive review of over 70 years of menopause science emphasizes the need for more research into symptom timeline and treatment effectiveness. The authors advocate for holistic, individualized approaches addressing physical and mental health impacts of menopause.
A new study reveals that a hotel's own sentiment score and its competitor's sentiment score have a significant impact on booking performance. Hotels that improve their own sentiment score by 1% can increase bookings by .38%, while those that improve their competitors' sentiment score by 1% can decrease bookings by .25%. The research al...
Researchers discovered that aging alters the pancreas's circadian rhythm by reorganizing its transcriptome. The study found that fibroblasts play a crucial role in regulating this reorganization, which affects the organ's resilience to aging-related pathologies.
Researchers found that infected individuals with multiple strains of the T. cruzi parasite were better able to control the disease, while those with a progressive form had fewer strains. This discovery provides a new framework for developing more effective treatments and vaccines.
The University of Miami has been awarded a $23.57 million grant from the National Institutes of Health (NIH) to join the Environmental influences on Child Health Outcomes (ECHO) Program. The research team will investigate how stress experienced by parents can affect their children's development.
A new study by Yale researchers found that despite reductions in fine particulate air pollution, racial and ethnic minorities still experience disproportionately high rates of cardiovascular disease-related deaths. The study found that Black people face the highest burden, with a mortality rate 4.59 times higher than white people in 2001.
A team of researchers at Dartmouth's Geisel School of Medicine has been awarded a $16.2 million grant to study inequities in healthcare for adults with Alzheimer’s disease and related dementias, with a focus on racialized and marginalized populations. The five-year renewal grant will explore how intersecting identities affect treatment...
Researchers at the University of Miami Miller School of Medicine identified distinct genomic events responsible for resistance to anti-BCMA and anti-GPRC5D immunotherapies in multiple myeloma. Mutations in the extracellular domain of BCMA impede T-cell binding without affecting protein expression or downstream signaling.
Researchers at University of Oxford have developed a miniaturized soft power source that can alter the activity of cultured human nerve cells, paving the way for miniature bio-integrated devices. The device uses internal ion gradients to generate energy, producing a current that persists for over 30 minutes.
The study validates a comprehensive genomic profiling assay, NeXT Dx, which detects single nucleotide variants, indels, copy number alterations, and gene fusions. The assay demonstrates high analytic sensitivities and specificity, providing personalized recommendations critical to clinical decision-making.
A team of international scientists found that coral reefs, marshes, and mangroves could be destroyed within the next 30 years from rising sea levels. Coastal habitats are essential for protecting coastlines, trapping carbon, and supporting millions of coastal residents.
The patented cooling pads designed by Purdue researchers improve feed intake and milk output in sows and increase piglet weaning weight. The technology also maintains boar semen quality and reduces heat stress abnormalities.
The American Heart Association introduces principles for data sharing to advance patient outcomes, highlighting transparency and privacy concerns. The new policy statement aims to protect patients' sensitive information while facilitating valuable research discoveries.
A new CNIC study confirms that controlling traditional cardiovascular risk factors can prevent Alzheimer's disease and dementia. Maintaining a low cardiovascular risk is linked to preserved cerebral glucose metabolism, indicating better brain health.
Researchers at the Laureate Institute for Brain Research found significant effects of floatation-therapy on body image and anxiety in patients with anorexia nervosa. The study showed immediate and sustained reductions in body image dissatisfaction and improved anxiety, which remained after treatment and lasted up to six months.
The guidance paper outlines reliable methods and research practices for improving evidence syntheses. It emphasizes the need for proper education in methodology and cautions against relying solely on appraisal tools and software programs.
The Norwegian approach to prison reform focuses on building relationships and trust, reducing solitary confinement. In a US pilot program, residents spent more time outside their cells, with a 74% drop in assaults and an 86% decrease in staff use-of-force incidents.
Research found that e-cigarette manufacturers use psychographic targeting to appeal to new users based on lifestyles and attitudes, particularly among low-risk young adults. The study suggests that stricter marketing regulations are needed to reduce exposure to these advertisements and minimize the risk of initiation.
A new study found that people who received free produce prescriptions experienced increased fruit and vegetable consumption, leading to improved body mass index, blood sugar, and blood pressure levels. This research suggests that produce prescription programs may be an effective way to address food insecurity and promote health.
Researchers propose integrated metasurfaces that can be combined with standard optical components like LEDs and LCDs for commercialization. Collaboration between industry and academia is crucial for developing innovative optical platforms.
A study by Pennington Biomedical Research Center and Woman's Hospital found that pregnant women in Louisiana were more likely to exceed recommended weight gain levels during the pandemic, with a 3-7% increase. This rise in non-optimal gestational weight gain may have long-term impacts on maternal and infant health.
The Graphene Flagship project has produced significant contributions to Europe's GDP and GVA, with an estimated return on investment of 14.5-fold. By 2030, the project aims to create over 81,000 jobs internationally.
New research led by Nansi Boghossian found that sickle cell disease contributes to racial disparities in severe maternal morbidity, with Black individuals at least 1.5 times more likely to experience complications. The study suggests preconception care and management are critical for improving pregnancy outcomes for patients with sickl...
A new MU study highlights the protective role of innate lymphoid cells and interferons in reducing neurological effects of Brucellosis. The findings could lead to improved diagnostics and therapies for neurobrucellosis, a condition that can cause long-term neurological complications.
A WVU astronomer is searching the Milky Way for debris left behind by supernovas, with $331,170 in NSF funding. He hopes to discover new supernova remnants using radio wavelength data from telescopes and machine-learning software.
Rapid Reviews Infectious Diseases will extend the successful preprint review model of Rapid Reviews COVID-19 to new research on infectious diseases like monkeypox, dengue fever, or herpes. The journal aims to accelerate the validation and diffusion of robust scientific findings through rapid peer review.
A new study published by the University of Rhode Island's Graduate School of Oceanography reveals extensive microplastic storage in Narragansett Bay, with an estimated 1,000 tons stored in the top 5 cm of its floor. The buildup has occurred over the last 10-20 years, primarily due to littering and runoff of single-use plastic items.
A new study by Harvard Pilgrim Health Care Institute found that residence in neighborhoods with higher opportunity or lower vulnerability is associated with a decreased risk of pediatric asthma. The study used a geographically diverse cohort of over 10,000 children and examined associations between neighborhood attributes and asthma in...
Research has clarified how starch granules form in wheat seeds, unlocking diverse potential benefits for various industries. The discovery of the enzyme PHS1 crucial for B-type granule initiation offers opportunities to create variations in starch for different food and industrial applications.
A microscopic crack in platinum grew and then 'healed' itself by getting shorter after repetitive stretching, confirming Dr. Michael Demkowicz's 2013 prediction. The experiment used nanocrystalline metals with a small grain size, which allows for microstructural features to interact with cracks.
Atrial fibrillation patients in the UK are now 50% less likely to die from heart attacks and strokes than at the start of the millennium. The study revealed significant health inequalities, with socioeconomically deprived patients facing a higher risk of mortality.
Researchers Elzbieta Izbicka and Robert T. Streeper discuss the evolution of cancer drug development, highlighting recent progress and emerging challenges due to environmental factors. They also examine how artificial intelligence may impact future drug development.
Researchers from Mount Sinai found that Asian Americans have a significantly high exposure to PFAS, with median exposure scores 89% higher than non-Hispanic whites. The study used advanced data science methods to account for complex exposure sources and heterogeneity across different groups.
Researchers at the University of Manchester are enhancing bioprinting technology to create new skin, bone, and tissue for transplantation in space. The project aims to protect astronauts' health from diseases like osteoporosis caused by microgravity exposure.
Researchers from Zhejiang University have discovered that Polygonatum sibiricum contains a significant amount of fructo-oligosaccharides, approximately 30% of the dry rhizome. These prebiotics promote gut health by fostering beneficial bacteria growth.
Researchers found a significant increase in pediatric trauma admissions during the COVID-19 pandemic, with younger patients and falls from moderate heights being more common. Blood alcohol levels were also higher in patients aged 14-18 years old, suggesting targeted interventions to curb alcohol use may be needed
A special section of WORK journal provides insights into the overlap and differences between ME/CFS and Long COVID, highlighting the importance of early recognition of post-exertional malaise (PEM) for symptom management. Researchers emphasize the need for specialized care and pacing as a therapeutic strategy to improve quality of life.
Climate impacts like dry summers causing tree growth reduction and increased mortality in the Black Forest. The study found a peak in tree mortality in 2019, with mortality rates exceeding 40% of sustainable annual growth.
Researchers discuss the essential role of macrophages in metastatic growth of lung colonies in melanoma, highlighting their importance in clearing challenges to tissue integrity and promoting growth-related processes. The authors emphasize the need for targeted therapies against macrophages to combat untreatable metastasis.
Researchers at UCSF and UC Berkeley have developed a brain-computer interface (BCI) that allows a woman with severe paralysis from a brainstem stroke to speak through a digital avatar. The system can decode brain signals into text at nearly 80 words per minute, making it a vast improvement over commercially available technology.
A new study found that catheter ablation significantly lowers the incidence of cardiovascular events and death in very old patients with nonvalvular atrial fibrillation. The researchers compared 208 patients who underwent AF ablation with those who received medical therapy only, finding a lower risk of both cardiovascular events and de...
The University of Tennessee Extension will address health disparities related to poor nutrition, physical activity, and obesity in seven rural Tennessee counties. The CDC's High Obesity Program funding aims to reduce chronic diseases by improving access to fresh foods and opportunities for physical activity.
Researchers from Zhejiang University discovered that Polygonatum sibiricum is devoid of noticeable starch, with approximately 30% of its dry rhizome consisting of fructo-oligosaccharides. These findings could revolutionize the understanding of Polygonatum's nutritional value and product development.
A new study finds SARS-CoV-2 infection significantly associated with development of high blood pressure in hospitalized adults. Persistent high blood pressure was more common in people with COVID-19 than influenza, highlighting potential long-term cardiovascular risk.
A recent study published in Neuron reveals that Noelin proteins play a crucial role in learning and memory formation in the mammalian brain. The study found that these proteins act as 'universal anchors' controlling the distribution and dynamics of AMPA receptors, which are essential for synaptic plasticity.
The new Southern Center for Maternal Health Equity will develop innovative approaches to reduce pregnancy-related complications and deaths in the Gulf South. The center aims to promote maternal health equity and address disparities in maternal mortality rates, particularly among Black pregnant and postpartum people.
A study by Diamond Light Source reveals that mixtures of Zn-aggregates/micro-polymers leach out from commercial products containing Zinc Oxide, harming aquatic life. Microplastics can carry zinc particles, which can be ingested by fish and other organisms.
A new MIT study reveals that soft technology features, such as permitting practices and supply chain management, contribute less than 15% to total cost declines in solar energy systems. Improving these processes could accelerate cost savings in the clean energy transition.
New research from the University of Ottawa's Telfer School of Management suggests that managing public transit projects requires a comprehensive approach considering rational, psychosocial, and political dimensions. This involves engaging stakeholders, including non-users, to ensure societal impact and cost-effectiveness.
Researchers expand simple view of reading framework using meta-analytic structural equation modeling, validating its effectiveness for SFL learners. Decoding skills and language comprehension skills are identified as primary components for effective SFL reading instruction.
Researchers used radiocarbon dating and time-series modeling to study the timing and causes of megafauna extinctions at Rancho La Brea Tar Pits. The team found that a sharp decline in population occurred between 13,070 to 12,900 years ago, coinciding with warming and drying climate change and increased fires sparked by humans.
A new study estimates that cancer screenings have saved the US at least $6.5 trillion and led to 12 million more years of life, with significant economic impact from breast, colon, cervical, and lung cancer screenings.
Glutamine metabolism plays a crucial role in cancer cell growth and survival, with its inhibition shown to block cancer cell growth in vivo and in vitro. A recent editorial paper suggests that glutamine dysregulation may also impact the tumor microenvironment, potentially leading to increased oxidative stress and cancer cell death.
A new technique converts kale waste into phytochemicals for use in health and personal care products, preserving potency and using non-toxic solvents. The method reduces energy consumption and emissions, making it attractive for industry adoption and supporting a circular economy.
Brazilian researchers discovered an enzyme that can replace traditional catalysts in the production of aviation biokerosene, increasing renewable biofuel output. The enzyme, OleTP RN, promotes deoxygenation and is selective for different sizes and types of carbon chain.
A new study published in the Journal of the American Heart Association found that people who experience pain after a heart attack are more likely to die within the next 8.5 years. The study analyzed data from over 18,300 adults who had a heart attack and found that moderate or extreme pain was linked to a higher mortality risk.
Researchers developed a novel method using Google Trends to assess player popularity and demonstrated its improvement in predicting market value. The method involves calculating six indicators of popularity that can be compared among players, improving accuracy when incorporated with other factors.
Researchers synthesized over 50 studies to find that mental simulations using visuals or verbal calls to action improve behavioral intentions and behavior. However, the effectiveness varies depending on the modality, frequency, type of consumption experience, and target populations.