Articles tagged with Research Impact
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Researchers synthesized over 50 studies to find that mental simulations using visuals or verbal calls to action improve behavioral intentions and behavior. However, the effectiveness varies depending on the modality, frequency, type of consumption experience, and target populations.
Researchers at Ohio State University have developed a new framework for studying neutrino self-interactions using supernovae. They found that in the burst case, unprecedented sensitivity to neutrino self-interactions is possible even with sparse data from SN 1987A and conservative analysis assumptions.
Research identifies key molecular signatures and pathways contributing to skeletal muscle strength loss in females with estrogen deficiency. The study found parallel patterns of inhibition and activation across various signaling pathways, including AMPK and calcium signaling.
Research found integrated behavioral health care improves children's mental health and school performance, supporting the potential benefits of pediatric integrated behavioral health care. The study, which included 51 children served by FQHCs in Massachusetts, showed significant improvements over 12 months.
Researchers developed a 'diversity factor' metric to capture paper's impact on health outcomes for all patients, particularly those in low- or middle-income countries. Most medical papers fail to meet this metric due to lack of diversity among authors and patient populations.
Researchers at NTU Singapore have developed a method to read data stored in antiferromagnets, allowing for potential energy-efficient and high-speed computing. This breakthrough could lead to the creation of new memory chips with improved performance and capacity.
Research reveals that a healthy gut microbiome can play a role in the acquisition and severity of HIV and EBV infections. The study found that animals colonized with resident microbiota had higher rates of HIV infection and increased viral loads, suggesting that altering the gut microbiota could be a potential therapeutic approach to c...
Researchers at West Virginia University are tracing the cause of diabetic heart disease using diabetic animal models to examine mitochondrial function. They hope to understand how faulty protein import affects the mitochondria and explore potential treatments to improve energy production and reduce cardiovascular risk.
The study analyzed the Parnaíba and São Francisco River basins, highlighting vulnerabilities to deforestation, fire, drought, poverty, and climate change. The SEVI index measures socio-environmental vulnerability, revealing 'very high' levels in 53% of the São Francisco basin.
WVU linguists analyze speech recordings to determine how intensity and duration shape pronunciation in American English and Spanish. The two-year study aims to redefine sound patterns across languages.
Researchers developed Fibro-Gel, an injectable hydrogel with tunable release profiles and biocompatibility, addressing limitations of conventional drug delivery via hydrogel. The system promotes wound healing with accelerated rates of new tissue regeneration and de novo tissue formation.
Researchers from Weizmann Institute of Science discovered that a subcategory of brain cells responds to stress in a totally different manner in males and females. The findings could lead to better understanding of health conditions affected by chronic stress, such as anxiety and depression.
Researchers explore CDK9 inhibitors as a promising combination partner in treating hematological malignancies. They discuss the role of cyclin-dependent kinases (CDKs) in these diseases and highlight the potential synergism with other drugs.
Researchers at Brigham and Women's Hospital have designed a probiotic to suppress autoimmunity in the brain, which is at the core of several diseases including MS. The treatment offers a more precise way to target brain inflammation with reduced negative side effects compared to standard therapies.
A WVU team is developing technology to detect and track lethal non-trackable space debris. The project aims to identify objects that can cause mission-ending damage to satellites and other space assets. The researchers will use a digital twin and simulation environment to test and evaluate their findings.
A new study found consistent increases in premature cardiovascular disease (CVD) death and disability due to particulate matter air pollution globally. The analysis, published in the Journal of the American Heart Association, revealed a 8.1% rise in age-standardized CVD deaths attributed to outdoor PM pollution between 1990 and 2019.
A team of scientists studied the impact of radiation on DNA, revealing that damaged areas are separated by a critical distance before breaking. The study found an exponential increase in DNA breakage time with distance, providing crucial information for effective DNA repair processes.
The American Heart Association is funding three new scientific research projects to examine the use of race in formulas that calculate risk and determine treatment for cardiovascular disease. The teams will assess potential bias in risk models, develop statistical methods to correct algorithm bias, and support equitable care.
Researchers found that inhibiting NLRP3 signaling reduces podocyte senescence, improves lifespan, and slows down healthy podocyte aging in mice. This discovery holds promise for treating age-related kidney diseases.
Researchers at the University of Missouri have developed a new method using nanopores to advance discoveries in neuroscience and medical applications. The technique allows for real-time detection of dynamic aptamer-small molecule interactions, which can aid in understanding DNA and RNA diseases and drug discovery.
Research from the University of Bath found that classroom environmental education activities do not necessarily translate to changes in children's attitudes towards animals and the environment. While these activities improved knowledge and awareness, they did not alter attitudes or encourage involvement in conservation efforts.
Dr. McKay will investigate the chemical composition of chromophores in DOM using advanced analytical tools and conduct measurements at the National High Magnetic Field Laboratory. His research aims to enhance predictions regarding DOM behavior and reactivity in the environment.
A UK-Sri Lankan research network aimed to develop research capacities among senior academic staff members from both countries. The training network investigated differences, overlaps, and synergies between Climate Change Adaptation (CCA) and Disaster Risk Reduction (DRR) research communities.
The study found that receiving videos or reminders increased consumption of media content about the issue, increased knowledge about available resources, and reported use of some resources in response to violence. However, long-term attitudes towards gender and marital equity remained unchanged.
A new study published in JNCCN found that the adoption of clinical research results led to a significant increase in the use of shorter adjuvant chemotherapy periods, with CAPOX becoming more widely used. The study also revealed disparities in treatment patterns, with Black patients being more likely to receive shorter chemotherapy reg...
Researchers genetically engineered plants to study lignin biosynthesis, but found a compound called pinoresinol restores growth by affecting root hair production. This suggests a broader function for pinoresinol in plant development beyond just lignin synthesis.
A WVU study found that U.S. cities with new professional sports teams saw increased influenza mortality rates, with the NHL teams causing the largest increase. The researchers analyzed data from 122 cities and controlled for factors like population and temperature to find a significant correlation between team arrival and flu deaths.
A Swansea University-led study found that Welsh breastfeeding rates increased during the pandemic, with a significant correlation between mothers' intention to breastfeed and exclusive breastfeeding duration. The study proposes targeted interventions during pregnancy and policies to support families to improve breastfeeding duration.
A University of Ottawa-led research team has made significant progress in understanding XLP-2, a genetic disorder that affects the immune system. The study reveals two underlying mechanisms: poor expression of Interleukin-6 and compromised T cell survival, which lead to immunodeficiency in patients.
Researchers studied 21 lowland meandering rivers on Earth and ancient Martian riverbeds to understand how climate change impacts river sinuosity. The study found that variable-sinuosity rivers continue changing, while constant-sinuosity rivers reach a steady state.
Researchers at Duke University Medical Center have identified a fatty molecule in breast milk that triggers a process in which stem cells produce new white matter, reversing neurological damage. This finding holds promise for developing therapies to treat preterm babies with cerebral palsy.
Researchers at the University of Gothenburg have developed a new strategy for producing oxygen-tolerant probiotics, including Faecalibacterium prausnitzii, which can improve glucose control. The combination of bacteria increased biomass and butyrate production, making it safe for human consumption.
Researchers have found an unusual ultrafast motion in layered magnetic materials, which could lead to breakthroughs in high-speed nanomotors for biomedical applications. The discovery was made using cutting-edge ultrafast probes and facilities, revealing a mechanical response across the entire sample.
Researchers found that adults who experienced violence, financial stress, or separation from parents as children were more likely to experience physical and cognitive impairments. Adverse childhood experiences can have lifelong consequences, including difficulty walking, carrying out daily activities, and problems with memory.
Researchers found that blocking dopamine transporters during mid-adolescence increases adult aggression, impulsivity, and the behavioral response to amphetamine in mice. Artificially stimulating dopaminergic neurons also exacerbated impulsive behavior in tasks. The study suggests potential harm from stimulant exposure in healthy teens ...
A new study by MU researcher Roy Thompson found that immigrant nurses in long-term care facilities often have more 'human capital' than their American-born counterparts, including language skills and additional certifications. This diversity can improve patient health outcomes and create a more equitable workforce.
The Global Atlas of Literacies for Health (GALH) is an interactive map displaying levels of health literacy and digital health literacy from evidence-based studies. The atlas provides a critical tool for literacy reform, enabling targeted interventions for marginalized groups.
Natural and social scientists must work together to address the climate crisis by understanding the complex interaction between environmental and social changes. The research highlights the importance of studying tipping points in both fields to inform climate change policies and practice.
A new multi-center study found that having a genetic variant in the prealbumin gene alone is not sufficient for diagnosing transthyretin amyloid cardiomyopathy in older Black patients. Researchers suggest that a blood test measuring prealbumin levels may be useful in identifying patients at risk of developing cardiac amyloidosis.
CHOP and Penn Medicine researchers have developed a proof-of-concept model for delivering gene editing tools directly into diseased blood cells within the body. This approach aims to reduce costs and increase access to gene therapies for blood disorders, which currently require chemotherapy and stem cell transplants.
A study examining Facebook users' news feeds found that reducing exposure to content from politically 'like-minded' sources had no measurable effect on political beliefs or attitudes during the 2020 US presidential election. The study also found that participants were exposed to more cross-cutting sources and less uncivil content after...
Researchers have identified KIAA0930 as a key factor causing muscle atrophy in cancer cells, which could lead to the development of new anti-cachexia therapies. The study found that KIAA0930 knockdown cells showed increased muscle mass and weight compared to control cells.
The American Heart Association has funded seven new scientific research projects to explore the connection between migraines, strokes, and cardiovascular disease. The studies will analyze existing datasets using machine learning and aim to create a collaborative group of experts to uncover the causes of increased risk.
Researchers at the University of Virginia Health System discovered that improper calcium signaling in mitochondria accelerates chronic inflammation, leading to age-related conditions. Increasing calcium uptake in macrophages may help prevent harmful inflammation and its effects on the brain.
Dr. Amir Asadi's team embeds patterned nanostructures into high-performance composites to achieve multifunctionality and structural integrity simultaneously. This approach offers a practical and scalable method for creating nanostructured materials with tunable properties, revolutionizing the manufacturing of high-performance composites.
Researchers found that service-based loan repayment programs like NHSC promote more diverse scope of practice, rural practice, and serving medically underserved populations. In contrast, PSLF may be less effective in supporting underrepresented backgrounds and directing physicians to these areas.
The study, published in Advanced Functional Materials, reveals a novel light-activated material that can be used to effectively reshape and thicken damaged corneal tissue, promoting healing and recovery for patients with keratoconus. The technology has tremendous potential to impact millions of people suffering from corneal diseases.
Arizona State University researchers have developed a novel method of using UV-C light to inhibit biofilm growth in almost any space. The team successfully inhibited biofilm growth by delivering UV-C light through side-emitting optical fibers at low irradiance levels, achieving results comparable to continuous light exposure.
Researchers at EMBL Heidelberg discovered that mutations in the RBM20 gene cause familial DCM by disrupting normal RNA splicing, leading to detrimental cytoplasmic granules. Targeted gene editing via CRISPR-Cas9 and restoring nuclear localisation of RBM20 could improve therapy options for patients.
A new multiplex assay has been developed to assess activated p300/CBP in circulating prostate tumor cells, revealing correlations with clinical outcomes and potential therapeutic targets for castration-resistant prostate cancer. The study found that patients with upregulated p300/CBP activity had shorter response times to ARSI therapy.
Dr. Eric Lazartigues has been recognized for his groundbreaking research on salt-sensitive hypertension and the role of the brain renin-angiotensin system in regulating blood pressure. His work has led to a deeper understanding of hypertension's impact on cardiovascular diseases and mortality.
A team of chemists developed a method to generate fluorochemicals without hydrogen fluoride, reducing energy requirements and carbon footprint. The new process mimics natural biomineralization, enabling the synthesis of over 50 different fluorochemicals directly from CaF2.
A study of 290 hospital referral regions found that 53.1% experienced load imbalance due to overcapacity, with Black patients disproportionately affected. The research emphasizes the need for better coordination of patient transfers and real-time data sharing across hospitals.
Researchers analyzed Twitter posts about the Philadelphia beverage tax before and after its implementation, finding a shift from anger to acceptance. The study's findings highlight the potential of social media data to influence public opinion and provide valuable insights for health policy makers.
Aerovy Mobility, a cloud solutions provider for electric aviation, received $140,000 from the Startup Foundry investment. The company plans to use the funds to launch its live operations tool, VEMS, at vertiports and airports worldwide. Uniform Sierra Aerospace, a drone manufacturer for public safety departments, also benefited from th...
Researchers at Politecnico di Milano used fibre optic sensors to monitor water pipelines and detected pressure anomalies caused by water leaks. The study's results confirm the possibility of identifying and localizing small water leaks, offering a potential solution to global water wastage.
Researchers developed a new tool to guide PPIE in health research, covering best practices and checklists for successful engagement. Patient partners played a key role in the study, contributing to the development of the tool and ensuring its relevance.
A large international database analysis found nearly a quarter of esophageal adenocarcinoma patients had normal endoscopies but were still diagnosed within a year. The study suggests using high-quality equipment, rigorous sampling protocols, and future research on biomarker panels to improve screening effectiveness.
Research found that mothers' childhood experiences and pregnancy anxiety are reflected in their 2-year-old children's gut microbiomes, with smaller populations of microorganisms and reduced genetic diversity. These changes may influence children's socioemotional development and brain-gut microbiome connection.
Researchers at Children's Hospital of Philadelphia found that NSAIDs exacerbate C. difficile infections by disrupting epithelial cell mitochondria, sensiting them to toxins. The study shows that NSAIDs and C. difficile toxins work synergistically to increase virulence, leading to increased disease severity and mortality.