Articles tagged with Research Impact
A year-long clinical trial found sustained remission of polymyalgia rheumatica in 28% of patients taking sarilumab, compared to 10% of those on placebo. The treatment showed promise in reducing relapse and improving outcomes for patients tapering their steroid medication.
Research from TU Dortmund University and RWTH Aachen University suggests that marketing academia has focused on identifying new phenomena, but neglected building 'big-picture' frameworks and theories. This limits the field's ability to provide answers to complex marketing problems.
Researchers found changes in microglial cells, a specialized subset of immune cells, that may worsen schizophrenia risk in adolescents. The study, published in Nature Communications, suggests that THC exposure during adolescence can lead to long-lasting negative effects on brain development and function.
Researchers at West Virginia University are studying the effects of acid rain on forests and watersheds, a project involving middle school students. The team aims to understand how ecosystems respond to chronic changes in environmental conditions, including the recovery phase after acid rain stops falling.
Researchers at Istituto Italiano di Tecnologia have developed the world's first rechargeable edible battery, utilizing food-grade materials like almonds and capers. The battery can power small electronic devices for a limited time and has potential applications in health monitoring, food storage, and children's toys.
NTU Singapore has expanded its research collaborations with French partners to push the boundaries of science. The university has inked six new partnerships and renewed existing collaborations across various fields, including quantum physics, nuclear energy, and sustainability.
The University of Cincinnati Cancer Center will support up to nine early-stage researchers with up to $80,000 in funding each over three years. This Institutional Research Grant aims to mentor junior faculty and advance cancer research.
Researchers urge caution due to harmful fungi that contaminate cannabis and hemp flowers, which can cause infections in susceptible individuals. The authors recommend developing a two-tier system to distinguish products intended for medical and recreational use to reduce harm to medical users.
A study by UC San Francisco researchers found that suspension from school is tied to a big drop in grade point average (GPA), especially for Black and Latinx children. The average GPA decline across all students who experienced an exclusionary school discipline (ESD) event was 0.88 points, with Black students seeing the largest decline...
Scientists have developed a technique to restore the function of human-derived GPCR proteins in yeast cells, which could accelerate research and lead to more effective treatments. The approach, using error-prone polymerase chain reaction, introduces random mutations that enhance protein stability and function.
The study, which analyzed data from older adults with peptic ulcer disease, revealed that approximately 1 in 8 individuals developed depression for the first time during the pandemic. Women, those who felt lonely, and those with functional limitations were at higher risk of depression. Targeted screening and intervention are being reco...
Researchers are testing a single target to weaken tumors and strengthen immune cells in pediatric brain tumor patients. The goal is to improve the effectiveness of CAR-T therapy, which has shown promise but also leads to exhaustion of immune cells.
Researchers from Columbia University have validated GLS2's ability to promote ferroptosis in murine models. This study suggests that targeting GLS2 may be a potential therapeutic strategy against liver diseases, particularly hepatocellular carcinoma.
The WVU School of Medicine and Benjamin M. Statler College of Engineering and Mineral Resources will support clinical trials and engineering technology development. The project aims to improve care and rehabilitation for people with neurological disorders through novel physician-engineer programs and human research.
A new electronic health record documentation tool has been shown to improve the accuracy and completeness of clinical documentation for patients undergoing treatment for epilepsy. This tool enables medical providers to identify patients who are failing treatments earlier, allowing for rapid optimization of positive outcomes.
A study by researchers at Keck School of Medicine of USC found that Black cancer survivors experience slowdowns in diagnosis and delivery of care due to exposure to racial discrimination. Positive interactions, such as ready access to providers and displays of empathy, were identified as key factors in improving care.
Researchers from Aarhus University found that current inventory methods rely solely on nitrogen content, neglecting degradability and leading to misleading inventories. The study suggests a distinction between mature and immature crop residues could improve accuracy and target mitigation strategies.
New research from MIT found that germicidal UV lights can produce potentially harmful compounds in indoor spaces. The study suggests that the lights should be used with appropriate ventilation to minimize health risks. Researchers emphasize that the new UV lights are not a replacement for ventilation but rather a complement to it.
Scientists propose new temperature guidelines for data centers that may help reduce energy consumption and save money. Researchers found that raising the temperature to around 41°C could lead to significant savings, with some areas able to rely entirely on free-cooling, reducing energy costs by up to 56%.
Researchers will study the spread of SARS-CoV-2 among deer, including captive and wild populations, as well as its relationship with humans and the environment. The project aims to understand disease ecology in whole systems and inform better management practices for deer producers.
Researchers at Gwangju Institute of Science and Technology (GIST) have developed a deep learning-based biosensing platform called DeepGT, which can accurately quantify nanoscale bioparticles, including viruses. The platform harnesses the advantages of Gires-Tournois biosensors and AI to refine visual artifacts and extract relevant info...
A team of researchers aims to develop drug therapies by targeting genes that affect metabolism in people with Down syndrome, potentially improving their quality of life. The project will focus on the protein SIM2, which has been linked to breast cancer and metabolic changes in individuals with the condition.
A study by Rutgers University finds that gun violence is tied to poverty, unemployment, and racial segregation, leading to poorer health and well-being in disadvantaged neighborhoods. The research highlights the need for long-term investments to reduce firearm-related violence and improve health outcomes.
A recent study reveals 15%-18% of the Brazilian Amazon is at high risk of ecological disruption by 2050. The regions, often near 'deforestation arc', exhibit low research frequencies and are threatened by climate change.
NJIT has received a $6 million NSF grant to translate science and engineering discoveries into market-ready technologies. The grant will fund up to 10 researchers for seed funding of $50,000 to $100,000 per project over four years. NJIT aims to become a regional leader in research translation.
A clinic-based community program improved food security scores, healthy eating behaviors, and depression scores in a vulnerable, food-insecure population. The Geaux Get Healthy Clinical Program provided comprehensive education and access to resources, leveraging community partnerships.
Producing new plastic via advanced recycling of post-use plastic reduces GHG emissions by 18-23% and fossil energy use by 65-70%. The study analyzed 2017-2021 data from eight companies and found a further 40-50% reduction when factoring in current end-of-life practices.
The American Phytopathological Society has created a new series of distinguished reviews in honor of Harold H. Flor, who developed the gene-for-gene concept in plant pathology. The series presents authoritative reviews on molecular plant-microbe interactions, providing a historical perspective and future directions for research.
A study found that daily mindfulness training at home reduced kids' stress levels and negative emotions, while a remote, app-based intervention showed improvements in mental health. Researchers suggest that mindfulness can support mental well-being and promote mental health in diverse children.
A new study finds that faces with acne, especially adult female acne, are perceived as less attractive, trustworthy, confident, successful, dominant, and happy. The study also highlights the emotional and psychological burden experienced by individuals with acne.
New technology enables self-sustaining modules to assemble, disassemble and recycle, offering unprecedented sustainability for electronic devices. The innovation is part of a larger field of Microelectronic Morphogenesis, which aims to replicate living systems through controlled form creation.
Researchers discovered that inhibiting the BRAF/EGFR/MEK pathway significantly reduced cancer stemness and drug resistance in primary colorectal cancer cells. The study also identified a triple combination treatment against BRAF, EGFR, and MEK as a promising approach to block these activities and develop effective treatments.
Researchers from the University of Notre Dame found that social media engagement improves when national and local levels mismatch audiences during recovery phases, increasing user engagement by 29.6%. The study suggests a nuanced approach to content coordination, with national headquarters leading production and local accounts following.
Researchers discovered the STAT3 signaling pathway as a potential target for treating H3K27M-mutant diffuse midline gliomas (DMGs), a uniformly lethal central nervous system malignancy. The current standard of care, including palliative radiation and chemotherapy, remains ineffective in this disease.
The University of Houston has received $5 million in DOE funding to develop high-performance superconducting tapes. The project aims to improve manufacturing efficiency and reduce costs, enabling the technology's widespread adoption in clean energy applications.
The Nuclear Science Advisory Committee has released a new long range plan, prioritizing the capitalization of substantial research investments to advance discovery in nuclear physics. The plan recommends increasing the research budget and continuing effective operation of national user facilities.
Researchers developed a promising strategy to reduce adverse reactions to nanoparticles by using complement inhibitors. The study showed that regulators being studied effectively inhibited complement activation by nanoparticles in human serum in vitro and animal models.
The study reports that UK natural science collections hold over 137 million items and contribute significantly to scientific, commercial, and societal benefits. Digitalizing these collections can unlock a seven- to ten-fold economic return on investment.
A new study published in the Journal of Marketing presents the Comparative Method of Valuation as a more accurate way to measure customers' willingness to pay. The study finds that existing methods can provide vague and inaccurate results due to their inability to capture relevant comparisons or context.
A new study examines cannabis use patterns, motivations, and risk factors among college students at a large public university in the southeastern US. The researchers found that top reasons for cannabis use were relaxation and social pressure, while daily users reported higher quantity of cannabis per day.
A breakthrough technique has been developed by University of Oxford researchers to repair brain injuries using 3D printing. Neural cells can be printed to mimic the architecture of the cerebral cortex, showing structural and functional integration with host tissue.
Researchers classify UGDH as a molecular indicator of tumor progression in multiple cancer types, describing its involvement in key canonical cancer signaling pathways. Methods to inhibit UGDH and its downstream products are also identified.
A new analysis estimates that switching all pet dogs and cats to vegan diets could spare nearly 2 billion land-based livestock animals yearly in the US, and nearly 7 billion globally. This could lead to significant reductions in environmental impacts such as land use, water consumption, and greenhouse gas emissions.
The Keck School of Medicine of USC has received a $2 million grant from the California Institute of Regenerative Medicine to further enhance its cutting-edge cGMP Laboratory. The funding will support the adoption of advanced technologies, including an electronic quality management system and optimized cell therapy manufacturing processes.
A new study aims to identify environmental and social factors contributing to Alzheimer's disease in older Black adults, who are up to two times more likely to develop the condition. Using remote cognitive assessments and biomarkers, researchers hope to gain a better understanding of the biopsychosocial factors behind this disparity.
Researchers created a tiny 3D cell culture model that mimics the function of lymphatic vessels to explore how inflammatory substances affect the lymphatic system. They found that certain cytokines cause cells to tighten their junctions, leading to reduced fluid drainage and swelling. Inhibiting a protein called ROCK2 reversed lymphedem...
Researchers at Northwestern University developed Lattice, a device that simulates human disease in multiple organs to analyze interactions and test new drugs. The technology can replicate complex disease processes, allowing scientists to study the effects of obesity on endometrial cancer, for example.
Researchers at Northwestern University identified a new evolutionarily conserved RNAi-based form of cell death called Death Induced by Survival gene Elimination (DISE), which targets essential survival genes in cancer cells. This mechanism is ancient and effective against all cancers tested.
Researchers found that administering precursors of Elovanoids improved neurological deficit in an experimental model of ischemic stroke. The study identified a cascade of gene responses and sheds light on potential new therapeutic avenues for treating ischemic strokes.
Cancer researchers at University of Cincinnati Cancer Center are exploring a new method called lattice therapy, which delivers higher doses to tumors and lower doses to surrounding tissues. The approach has shown promise in reducing treatment time and improving patient outcomes for head and neck, lung, and brain tumors.
The Human Brain Project has driven outstanding advances in brain research and medicine, producing over 3000 academic publications and 160 digital tools. The EBRAINS infrastructure will remain accessible to the scientific community after the project's end.
The University of Manchester will advance understanding of microbial communities and their impact on the world. The £5.4m project aims to engineer bespoke microbial communities for applications such as CO2 conversion, contributing to a more sustainable Net Zero future.
Researchers propose analysis protocol to evaluate feasibility of silicon-containing batteries with reduced particle size and uniform dispersion. The study finds promising results from innovative synthesis technology and initial efficiencies exceeding 90% with improved lifespan characteristics.
Research highlights the challenges of rural hospital-based maternity unit closures and transportation barriers, leading to delays in care and adverse outcomes. The study suggests that telehealth services can provide a solution to address these disparities in maternal health outcomes.
Researchers found differential activation patterns of the Default Mode Network nodes, with facial movement inducing an inverted positive BOLD pattern in certain areas. Facial recognition and movement uniquely impact brain activity, highlighting their importance in cognitive and social development.
Researchers found that etripamil nasal spray restored normal heart rhythms within 30 minutes in 54% of patients, making it a potential new option for self-treating paroxysmal supraventricular tachycardia. The study showed the medication to be safe and well-tolerated.
A Boston University-led study identified genetic signatures of TB-susceptible and TB-resistant macrophages, leading to a new approach to tweak the immune system to fight the disease. The research could lead to therapies targeting host immunity to tuberculosis.
The article discusses the need to reassess COVID-19 precautions in 2023, particularly for patients with hematologic malignancies. The researchers highlight the increased risk of poor response to vaccination and worse outcomes from COVID-19 infection among these patients.
Researchers at the University of Illinois have successfully tuned graphene surface friction using external electric fields, allowing for dynamic control of friction. This breakthrough could lead to reduced energy consumption in nano- and micro-electromechanical systems and mitigate wear and corrosion of sliding surfaces.
A U of M Medical School professor has received a $3.5 million grant to develop a reproductive health curriculum for Tanzania that addresses the needs of people with disabilities. The project aims to improve healthcare services and build in-country capacity for comprehensive sexual and reproductive healthcare.