News on measuring and increasing the impact of research. Covers research-impact data, AI publishing workflows, open-access programs, and scholarly metrics.
Researchers found that tumor-resident T-cell receptor sequences showed high complementarity with the cancer testis antigen DDX53, suggesting an immune response that selects for DDX53-negative cells. This association was correlated with worse disease-free survival rates, highlighting a potential early esophageal cancer antigen.
A review of 23 years of neuroimaging research finds that screen time affects the pre-frontal cortex and other brain regions involved in executive functions, memory, and processing. Digital experiences may shape children's brains and influence cognitive development, with both positive and negative impacts.
Researchers investigate nanoparticles for cancer treatment, hoping to reduce side effects and improve efficacy. La-Beck's lab aims to understand the body's interaction with nanoparticles and their impact on tumor growth and immune responses.
A study analyzing European Parliament politicians' views on degrowth and green growth reveals a surprising lack of consensus on both sides. Despite its popularity among centre-right MEPs, green growth is seen as a more divisive concept than previously thought, with no clear majority supporting it.
Researchers at Weill Cornell Medicine found that partnering with local religious leaders increased the adoption of family planning methods in Tanzania. The approach, which involves workshops and training for faith leaders, led to a 19% rise in contraceptive uptake in communities where religious leaders participated.
Researchers aim to identify contaminants in ash, soil, and surface waters from the Maui fire, posing risks to human health. The study will also help educate communities on the presence and risk of contaminants, informing prevention measures for future fires.
The American Heart Association's National Hispanic Latino Cardiovascular Collaborative aims to bridge the gap in healthcare disparities affecting underrepresented groups. By empowering Hispanic Latino leaders, the program seeks to eliminate health inequities and improve overall well-being.
Elea Abisamra's STEM writing program at Virginia Tech has been recognized by the journal Cell for its innovative approach to teaching science through storytelling. The program has already helped 95 kids publish books with over 150 tutors as editors, and plans to expand globally.
A UCLA study found that hospitals with high patient diversity are less likely to offer core cancer services, including hospice care, chemotherapy, and robotic surgery. The lack of these resources can impact treatment quality and outcomes for patients diagnosed with cancer.
A study by Dr Lixin Ren found that extracurricular activities have a limited impact on math skills in preschool children, with effects dependent on behavioral regulation and approaches to learning. For children with poor self-regulation skills, structured activities can improve early math skills.
A study of house finches found that sick birds are more social than healthy ones, preferring to eat with their flock. This behavior may be driven by the benefits of group living for sick birds, but also poses a risk to healthy birds due to increased disease transmission.
Researchers have summarized recent advances in enzyme-activated near-infrared fluorescent probes for non-invasive visualization of enzyme dynamics and disease status. These probes offer high specificity, sensitivity, and biocompatibility, making them valuable assets in biomedical research and healthcare.
A comprehensive review study identifies emerging biomarkers that mirror efforts to halt beta-cell autoimmunity, offering potential applications in clinical practice. The study's findings may improve the management of type 1 diabetes during its partial remission phase.
A study by Brown University researchers found that government-sanctioned overdose prevention centers in New York City were not associated with a significant increase in crime. The analysis of five administrative datasets showed no changes in violent crimes, property crimes, or calls for emergency services in the surrounding neighborhoods.
Jenny Wilkerson receives $1.94 million grant to develop novel models and investigate antinociceptive profiles of basal sex hormone alterations in patients with chronic post-op pain. The study aims to answer questions about the impact of altered sex hormone levels on recovery times, drug effectiveness, and long-term health.
A team of researchers from Pitt and Notre Dame have received a $2 million NSF grant to develop 'chiplets' - refurbished integrated chips that can be reused in new products, reducing manufacturing waste and emissions. The project aims to create a more sustainable computing lifecycle by mapping the reuse of decommissioned FPGAs.
A new study reveals that C4 crops are significantly less sensitive to ozone pollution than C3 crops, with potential implications for improving crop productivity and resilience. The research suggests that C4 bioenergy feedstocks can maintain performance in regions with high ozone levels.
Research suggests that diverse forests can capture approximately 226 Gigatonnes of carbon, but this potential can be achieved by incentivizing community-driven efforts to promote biodiversity. Restoration efforts should include natural diversity of species and sustainable practices.
Researchers found that people with overweight or obesity who took semaglutide for over 3 years had a 20% lower risk of heart attack, stroke, or death from cardiovascular disease. The study showed significant weight loss and improved cardiovascular outcomes in adults without diabetes.
A single dose of zilebesiran safely and effectively lowered systolic blood pressure in people with mild-to-moderate high blood pressure for up to six months. The study found significant reductions in daytime and nighttime systolic blood pressure, as well as low rates of adverse events.
A new study suggests that a PCSK9 inhibitor given every 1-3 months may effectively lower bad cholesterol levels in people with non-genetic hypercholesterolemia. The medication, recaticimab, showed similar effectiveness and safety as other PCSK9 inhibitors when administered less frequently.
Researchers adapted a COVID-19 collaboration to monitor near-real-time trends in substance use-related hospital and emergency department visits. Detailed data shows large increases in methamphetamine- and opioid-involved hospital and ED visits among Native American, Black, and multiple-race populations.
Researchers at Rice University have discovered a way to transform a rare-earth crystal into a magnet by using chirality in phonons. Chirality, or the twisting of atoms' motion, breaks time-reversal symmetry and aligns electron spins, creating a magnetic effect.
Yu Yang's NSF-funded research aims to reduce vehicle emissions and promote the use of electric bikes and scooters by developing socially informed traffic signal control systems. The project involves a three-pronged method that uses low-cost mobile air-quality sensing, spatial-temporal graph diffusion learning, and reinforcement learnin...
Ravi Neelipally, a PhD student at the University of Tennessee Institute of Agriculture, is investigating organic wheat-soybean double-cropping systems. His research aims to develop management practices that combat misconceptions surrounding organic farming's productivity and profitability.
The Southwest-Midwest Pediatric Device Innovation Consortium has supported over 200 pediatric device innovators and companies, developing several devices in the past five years. The consortium's portfolio includes real-world evidence research projects using digital tools for collecting and analyzing patient data.
A study published in The Lancet Regional Health - Europe found that ambient temperature is strongly associated with inpatient mortality from respiratory diseases, particularly during the warm season. The research suggests that high temperatures contribute to an increase in fatal hospital admissions, especially in Barcelona.
A University of Houston research team integrated machine learning with SHAP analysis to identify the city's air pollution sources more accurately. The study found that the oil and gas industry had the highest impact on emissions, while shortwave radiation and relative humidity were key influencing factors for overall ozone concentration.
Research highlights the association between traumatic events and insufficient/excessive sleep duration in US children. The analysis of over 100,000 children found that traumatic events magnify the adverse effects of poor sleep on cardiovascular health.
A six-month produce prescription program improved hemoglobin A1c levels, indicating better blood sugar control. Participants also showed improved food security and nutrition security.
Research highlights the importance of supporting family members after cardiac arrest, finding that they face significant emotional, physical, and informational challenges. Studies such as TEMPO found that informational resources improve caregiver knowledge and decision-making abilities.
Researchers from Tohoku University developed a model that simulates fish tail fin motion and reveals the underlying mechanisms behind synchronized swimming. The study found that synchronizing fin movements reduces energy dissipation, but the optimal timing may not always lead to conservation of energy.
A recent study in JAMA Cardiology analyzed data from 15,000 patients and found that enteric coating on aspirin does not change its effectiveness or safety for secondary prevention of cardiovascular events. The study suggests that patients can choose the aspirin formulation that suits them best.
Researchers found restricted abortion access led to more children entering foster care, with a 15% increase for Black and racial minority children. The study used state-level data to evaluate the link between abortion restrictions and foster care entries.
Two reproductive health conditions, polycystic ovary syndrome and dysmenorrhea, are linked to increased cardiovascular disease risk in women. Studies suggest that girls with polycystic ovary syndrome have a 30% higher risk of high blood pressure, while women with dysmenorrhea are twice as likely to experience ischemic heart disease.
A Brown University research team investigated belly flop mechanics, finding that flexible impactors can sometimes increase the maximum impact force on the body, contradicting conventional thinking. The study's findings have implications for naval and marine engineering applications.
A new MU study shows that high school students who attended college-run STEM Career Days were far more likely to have STEM-related career aspirations than those who did not attend. The study highlights the benefits of introducing high school students to STEM opportunities and can help increase diversity in the STEM workforce.
A study published in Oncotarget reveals that HER2 mutant alleles play a crucial role in determining treatment response to neratinib and poziotinib. Researchers found that individual HER2 mutant alleles have distinct effects on therapeutic efficacy, suggesting new targets for breast cancer therapy.
Researchers found that green spaces alleviate extreme heat's negative impacts on human health, while densely packed buildings increase mortality risk. Urban design strategies incorporating different types of greenery are recommended to mitigate heatwave-associated mortality.
Venkat's project aims to reduce attack response time and protect programs from other attacks by developing a 'decoupled' security response system. His approach could help stop emerging zero-day cyberattacks within 24-48 hours, reducing time and dollar costs of frequent patching.
A VCU-led study found that pharmacists' ability to treat patients with hypertension could prevent millions of heart attacks, strokes, and other cardiovascular events. The study estimates a cost savings of $1.1 trillion over 30 years, with significant economic and quality-of-life impacts.
Researchers uncover unique brain network dysfunctions in adolescents with major depressive disorder (MDD), highlighting areas of increased activity and decline. The study's findings hold promise for refining diagnosis and developing new treatment strategies.
A new study by Anglia Ruskin University and University of Oxford highlights the lack of clinical research on severe sight impairment (SSI) among working-age individuals in the UK. The study finds that inherited retinal disorders, such as IRDs, are under-researched despite being a leading cause of SSI certifications in this population.
Researchers at Ohio State University will investigate the role of microglia cells in chronic inflammation and neuronal dysfunction after TBI, with a focus on preventing long-term consequences. The $7.7 million award aims to develop innovative healthcare solutions for traumatic brain injury survivors.
A recent study analyzing global and national trends of atherosclerosis found an increasing trend in incidence from 1990 to 2019, driven by adults aged 20–54. The burden of the disease is particularly concerning in low- and middle-income countries, where it is rising significantly due to lifestyle factors and aging populations.
A new study found that sensory differences exacerbate loneliness and poor mental health in Autistic adults, highlighting the need for inclusive social spaces. The research also showed that financial inequalities and lack of employment opportunities contribute to feelings of isolation among Autistic individuals.
Dr. Olugbenga Ogedegbe has been recognized for his pioneering research on health disparities, chronic diseases, and cardiovascular risk reduction, particularly among Black adults in the US. His work aims to reduce hypertension control and racial inequities in cardiovascular disease outcomes.
A University of Missouri study found that opioid-dependent mothers experience stigma, leading to withdrawal from healthcare and negative outcomes for their infants. The research highlights the need for compassionate support and education to promote better health outcomes.
Dr. Marc A. Pfeffer will receive the 2023 Eugene Braunwald Academic Mentorship Award for his remarkable teaching and mentoring career, which has inspired numerous professionals in cardiovascular medicine. He is credited with directly mentoring 58 individuals throughout their careers.
Dr. Zainab Mahmoud received the 2023 Dr. Nanette K. Wenger Research Goes Red Award for her study identifying racial disparities in specific maternal cardiovascular outcomes. The analysis found higher rates of hospitalizations among Black women, highlighting the need for improved access to care and enhanced postpartum monitoring.
Researchers found that FAAH inhibition reduced breast cancer growth in immunodeficient mice and induced apoptosis of breast cancer cells. The combination of FAAH inhibitors and endocannabinoids was the most effective treatment approach.
Dr. Schwamm, a neurologist at Yale School of Medicine, is recognized for his work on stroke systems of care and telestroke initiatives. He has improved patient outcomes and expanded access to care through his advocacy for telemedicine and digital health solutions.
A new study from Tulane University found that frequent salt consumption is associated with a higher risk of developing Type 2 diabetes. The study surveyed over 400,000 adults and found participants who regularly added salt had a 13% to 39% increased risk of developing the disease compared to those who never or rarely used salt.
A small clinical trial led by the University of Houston demonstrates Riluzole's effectiveness in improving functionality in people with acute spinal cord injuries. The study used an SCI-specific biomarker to show how Riluzole reduces neuron cell damage and improves motor abilities.
The American Heart Association will present Dr. Pradeep Natarajan with the 2023 Joseph A. Vita Award for his groundbreaking research in genetic analysis of cardiovascular disease risk and discovery of new genes responsible for coronary artery disease. His work is propelling the future of preventive cardiovascular medicine.
Researchers found that Singapore's coasts were resilient during high sea-level rise rates due to high sedimentation rates. This study provides new insights into the interplay between rising sea levels and sedimentation.
Dr. Marlene Rabinovitch, a renowned pediatric cardiologist, will receive the 2023 Research Achievement Award for her groundbreaking research on PAH treatment. Her discoveries have led to the identification of neutrophil elastase as a trigger for inflammatory responses and the potential use of immunosuppressant FK506 to restore lung blo...
Researchers found a total of 4,721 proteins altered with age in the murine ovary, including upregulated ECM proteins associated with fibrosis. Age-dependent changes also affect immune response pathways and unique immune cell populations.
Researchers find that halting deforestation and restoring native vegetation are critical for Brazil to achieve its 2050 net zero goal. The study suggests that nature-based solutions can mitigate nearly 80% of Brazil's net zero pledge and reduce carbon emissions by 781 million tons per year.
A new study finds that heat-related cardiovascular deaths may more than double in the US by the middle of the century, with elderly and Black adults being most at risk. The projections suggest that reducing greenhouse gas emissions can mitigate this impact, but infrastructure interventions such as increasing tree cover may also be effe...